Mutant huntingtin affects the rate of transcription of striatum-specific isoforms of phosphodiesterase 10A

European Journal of Neuroscience

Volumn 20, Issue 12, 2004, Pages 3351-3363

  Hu, Haibei ^a   McCaw, Elizabeth A ^a   Hebb, Andrea L O ^a   Gomez, Geraldine T ^a   Denovan Wright, Eileen M ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Huntington's disease; Quantitative RT PCR; R6 transgenic mice; RNase protection assay

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HUNTINGTIN; ISOENZYME; MESSENGER RNA; MUTANT PROTEIN; NEURON RESTRICTIVE REGULATORY ELEMENT; PHOSPHODIESTERASE; PHOSPHODIESTERASE 10A; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; EXON; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC CONSERVATION; HUNTINGTON CHOREA; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYADENYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY; RNA STABILITY; RNA TRANSCRIPTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSGENE; TRANSGENIC MOUSE;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CORPUS STRIATUM; HUMANS; HUNTINGTON DISEASE; ISOENZYMES; MALE; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOSPHORIC DIESTER HYDROLASES; SUBSTRATE SPECIFICITY; TRANSCRIPTION, GENETIC;

EID: 10944265363     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2004.03796.x     Document Type: Article

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