Both acute and chronic buspirone treatments have different effects on regional 5-HT synthesis in Flinders Sensitive Line rats (a rat model of depression) than in control rats

Neurochemistry International

Volumn 54, Issue 3-4, 2009, Pages 205-214

  Nishi, Kyoko ^a   Kanemaru, Kazuya ^a   Hasegawa, Shu ^a   Watanabe, Arata ^a   Diksic, Mirko ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

5 HT synthesis increase; 5 HT1A agonist; Depression model; Tracer measurements; Tryptophan analog

Indexed keywords

BUSPIRONE; SEROTONIN;

ACUTE DRUG ADMINISTRATION; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CHRONIC DRUG ADMINISTRATION; CONTROL GROUP; CONTROLLED STUDY; DEPRESSION; DORSAL RAPHE NUCLEUS; DRUG EFFECT; EXPERIMENTAL MODEL; FLINDERS RESISTANT LINE RAT; FLINDERS SENSITIVE LINE RAT; FRONTAL CORTEX; HIPPOCAMPUS; MEDIAN RAPHE NUCLEUS; NONHUMAN; OLFACTORY NUCLEUS; PARIETAL LOBE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; RAT STRAIN; RETICULAR FORMATION; SEROTONINERGIC SYSTEM; SOMATOSENSORY CORTEX; SPRAGUE DAWLEY RAT; SUBSTANTIA NIGRA; UPREGULATION; VISUAL CORTEX;

ANIMALS; BRAIN; BRAIN MAPPING; BUSPIRONE; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; GENETIC PREDISPOSITION TO DISEASE; IMMUNITY, INNATE; RATS; RATS, INBRED STRAINS; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN; SEROTONIN AGONISTS; SPECIES SPECIFICITY; UP-REGULATION;

RATTUS;

EID: 60949084197     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2008.10.010     Document Type: Article

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