Inhibition of peptidylglycine α-amidating monooxygenase by exploitation of factors affecting the stability and ease of formation of glycyl radicals

Journal of the American Chemical Society

Volumn 126, Issue 41, 2004, Pages 13306-13311

  Barratt, Brendon J W ^a   Easton, Christopher J ^a   Henry, David J ^a   Li, Iris H W ^a   Radom, Leo ^a,b   Simpson, Jamie S ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; FREE RADICALS; HORMONES;

FREE RADICAL BROMINATIONS; MONOOXYGENASE; RADICAL STABILIZATION ENERGY;

ENZYMES;

ALPHA AMIDATING ENZYME; GLYCINE DERIVATIVE; GLYCOLIC ACID; HORMONE PRECURSOR; PEPTIDE HORMONE; RADICAL; UNSPECIFIC MONOOXYGENASE;

AMINATION; AMINO ACID SUBSTITUTION; ARTICLE; BIOSYNTHESIS; BROMINATION; CATALYSIS; ENERGY; ENZYME BINDING; ENZYME INHIBITION; HORMONE SYNTHESIS; MOLECULAR STABILITY; PROTEIN DEGRADATION;

BROMOSUCCINIMIDE; FREE RADICALS; GLYCINE; HYDROCARBONS, BROMINATED; KINETICS; MIXED FUNCTION OXYGENASES; MULTIENZYME COMPLEXES; THERMODYNAMICS;

EID: 6044274627     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja046204n     Document Type: Article

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