Mechanistic investigation of peptidylglycine α-hydroxylating monooxygenase via intrinsic tryptophan fluorescence and mutagenesis

Biochemistry

Volumn 42, Issue 23, 2003, Pages 7133-7142

  Bell, Joseph ^a,b   El Meskini, Rajaâ ^a   D'Amato, Darlene ^a   Mains, Richard E ^a   Eipper, Betty A ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CRYSTALLOGRAPHY; FLUORESCENCE; MUTAGENESIS; PH EFFECTS;

TRYPTOPHAN FLUORESCENCE;

PROTEINS;

ALPHA AMIDATING ENZYME; COPPER; OXYGEN; TRYPTOPHAN; TYROSINE;

ACIDITY; ALKALINITY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTALLOGRAPHY; ELECTRON TRANSPORT; ENZYME ACTIVITY; FLUORESCENCE; KINETICS; PRIORITY JOURNAL; REACTION TIME; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY;

ANIMALS; BINDING SITES; CATALYSIS; CELL LINE; CHO CELLS; COPPER; CRICETINAE; GLYCINE; KINETICS; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; OLIGOPEPTIDES; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; TRYPTOPHAN;

EID: 0037793356     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034247v     Document Type: Article

References (34)

1. Blain, I., Slama, P., Giorgi, M., Tron, T., and Reglier, M. (2002) J. Biotechnol. 90, 95-112.
2. Decker, H., and Terwilliger, N. (2000) J. Exp. Biol. 203, 1777-1782.
3. McGuirl, M. A., and Dooley, D. M. (1999) Curr. Opin. Chem. Biol. 3, 138-144.
4. Prigge, S. T., Mains, R. E., Eipper, B. A., and Amzel, L. M. (2000) Cell. Mol. Life Sci. 57, 1236-1259.
5. Garcia-Borron, J. C., and Solano, F. (2002) Pigm. Cell Res. 15, 162-173.
6. Jaron, S., and Blackburn, N. J. (1999) Biochemistry 38, 15086-15096.
7. Boswell, J. S., Reedy, B. J., Kulathila, R., Merkler, D. J., and Blackburn, N. J. (1996) Biochemistry 35, 12241-12250.
8. Jaron, S., and Blackburn, N. J. (2001) Biochemistry 40, 6867-6875.
9. Reedy, B. J., and Blackburn, N. J. (1994) J. Am. Chem. Soc. 116, 1924-1931.
10. Eipper, B. A., Quon, A. S. W., Mains, R. E., Boswell, J. S., and Blackburn, N. J. (1995) Biochemistry 34, 2857-2865.
11. Freeman, J. C., Villafranca, J. J., and Merkler, D. J. (1993) J. Am. Chem. Soc. 115, 4923-4924.
12. Kulathila, R., Merkler, K. A., and Merkler, D. J. (1999) Nat. Prod. Rep. 16, 145-154.
13. Kulathila, R., Consalvo, A. P., Fitzpatrick, P. F., Freeman, J. C., Snyder, L. M., Villafranca, J. J., and Merkler, D. J. (1994) Arch. Biochem. Biophys. 311, 191-195.
14. Blackburn, N. J., Rhames, F. C., Ralle, M., and Jaron, S. (2000) JBIC, J. Biol. Inorg. Chem. 5, 341-353.
15. Prigge, S. T., Kolhekar, A. S., Eipper, B. A., Mains, R. E., and Amzel, L. M. (1999) Nat. Struct. Biol. 6, 976-983.
16. Kolhekar, A. S., Keutmann, H. T., Mains, R. E., Quon, A. S. W., and Eipper, B. A. (1997) Biochemistry 36, 10901-10909.
17. Kolhekar, A. S., Bell, J., Shiozaki, E. N., Jin, L., Keutmann, H. T., Hand, T. A., Mains, R. E., and Eipper, B. A. (2002) Biochemistry 41, 12384-12394.
18. Bell-Parikh, L. C., Eipper, B. A., and Mains, R. E. (2001) J. Biol. Chem. 276, 29854-29863.
19. Prigge, S. T., Kolhekar, A. S., Eipper, B. A., Mains, R. E., and Amzel, L. M. (1997) Science 278, 1300-1305.
20. Fersht, A. (1985) Enzyme structure and mechanism, W. H. Freeman and Co., New York.
21. Segel, I. H. (1975) Enzyme kinetics: behavior and analysis of rapid equilibrium and steady-state enzyme systems, John Wiley and Sons, New York.
22. Lakowicz, J. R. (1999) Principles of fluorescence spectroscopy, Kluwer Academic/Plenum, Boston.
23. Clayton, A. H., and Sawyer, W. H. (2002) Eur. Biophys. J. 31, 9-13.
24. Cioni, P., and Strambini, G. B. (2002) Biochim. Biophys. Acta 1595, 116-130.
25. O'Halloran, T. V., and Culotta, V. C. (2000) J. Biol. Chem. 275, 25057-25060.
26. Walsh, C. (1979) Enzymatic Reaction Mechanisms, W. H. Freeman and Co., San Francisco.
27. Tamburini, P. P., Jones, B. N., Consalvo, A. P., Young, S. D., Lovato, S. J., Gilligan, J. P., Wennogle, L. P., Erion, M., and Jeng, A. Y. (1988) Arch. Biochem. Biophys. 267, 623-631.
28. Jaron, S., Mains, R. E., Eipper, B. A., and Blackburn, N. J. (2002) Biochemistry 41, 13274-13282.
29. Driscoll, W. J., Konig, S., Fales, H. M., Pannell, L. K., Eipper, B. A., and Mueller, G. P. (2000) Biochemistry 39, 8007-8016.
30. Francisco, W. A., Merkler, D. J., Blackburn, N. J., and Klinman, J. P. (1998) Biochemistry 37, 8244-8252.
31. Francisco, W. A., Knapp, M. J., Blackburn, N. J., and Klinman, J. P. (2002) J. Am. Chem. Soc. 124, 8194-8195.
32. Brenner, M. C., and Klinman, J. P. (1989) Biochemistry 28, 4664-4670.
33. Kaufman, S. (1974) J. Psychiatr. Res. 11, 303-316.
34. Friedman, S., and Kaufman, S. (1965) J. Biol. Chem. 240, 4763-4773.