-
1
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
Campisi J, D'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007 ; 8 : 729-40.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 729-740
-
-
Campisi, J.1
D'Adda di Fagagna, F.2
-
2
-
-
44349136891
-
Telomere dysfunction and tumour suppression: The senescence connection
-
Deng Y, Chan SS, Chang S. Telomere dysfunction and tumour suppression: the senescence connection. Nat Rev Cancer 2008 ; 8 : 450-8.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 450-458
-
-
Deng, Y.1
Chan, S.S.2
Chang, S.3
-
3
-
-
41549149451
-
Cellular senescence in vivo: A barrier to tumorigenesis
-
Prieur A, Peeper DS. Cellular senescence in vivo: a barrier to tumorigenesis. Curr Opin Cell Biol 2008 ; 20 : 150-5.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 150-155
-
-
Prieur, A.1
Peeper, D.S.2
-
4
-
-
33645526114
-
Oncogene-induced senescence: Putting the brakes on tumor development
-
Braig M, Schmitt CA. Oncogene-induced senescence: putting the brakes on tumor development. Cancer Res 2006 ; 66 : 2881-4.
-
(2006)
Cancer Res
, vol.66
, pp. 2881-2884
-
-
Braig, M.1
Schmitt, C.A.2
-
5
-
-
2342570379
-
Hallmarks of senescence in carcinogenesis and cancer therapy
-
Shay JW, Roninson IB. Hallmarks of senescence in carcinogenesis and cancer therapy. Oncogene 2004 ; 23 : 2919-33.
-
(2004)
Oncogene
, vol.23
, pp. 2919-2933
-
-
Shay, J.W.1
Roninson, I.B.2
-
6
-
-
33845338765
-
Cellular senescence and cancer treatment
-
Schmitt CA. Cellular senescence and cancer treatment. Biochim Biophys Acta 2007 ; 1775 : 5-20.
-
(2007)
Biochim Biophys Acta
, vol.1775
, pp. 5-20
-
-
Schmitt, C.A.1
-
7
-
-
29244485921
-
The senescent side of tumor suppression
-
Collado M, Serrano M. The senescent side of tumor suppression. Cell Cycle 2005 ; 4 : 1722-4.
-
(2005)
Cell Cycle
, vol.4
, pp. 1722-1724
-
-
Collado, M.1
Serrano, M.2
-
8
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000 ; 100 : 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
9
-
-
34447636233
-
Remodeling chromatin for senescence
-
Adams PD. Remodeling chromatin for senescence. Aging Cell 2007 ; 6 : 425-62.
-
(2007)
Aging Cell
, vol.6
, pp. 425-462
-
-
Adams, P.D.1
-
10
-
-
33847703331
-
Cellular senescence and chromatin organisation
-
Narita M. Cellular senescence and chromatin organisation. Br J Cancer 2007 ; 96 : 686-91.
-
(2007)
Br J Cancer
, vol.96
, pp. 686-691
-
-
Narita, M.1
-
11
-
-
34047205692
-
SUMO is growing senescent
-
Bischof O, Dejean A. SUMO is growing senescent. Cell Cycle 2007 ; 6 : 677-81.
-
(2007)
Cell Cycle
, vol.6
, pp. 677-681
-
-
Bischof, O.1
Dejean, A.2
-
12
-
-
34247580184
-
Telomeres limit cancer growth by inducing senescence: Long-sought in vivo evidence obtained
-
Sedivy JM. Telomeres limit cancer growth by inducing senescence: long-sought in vivo evidence obtained. Cancer Cell 2007 ; 11 : 389-91.
-
(2007)
Cancer Cell
, vol.11
, pp. 389-391
-
-
Sedivy, J.M.1
-
13
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R, Fumagalli M, Cicalese A, et al. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 2006 ; 444 : 638-42.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
-
14
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J, Rezaei N, Liontos M, et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 2006 ; 444 : 633-7.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
-
15
-
-
0042420304
-
DNA damage foci at dysfunctional telomeres
-
Takai H, Smogorzewska A, de Lange T. DNA damage foci at dysfunctional telomeres. Curr Biol 2003 ; 13 : 1549-56.
-
(2003)
Curr Biol
, vol.13
, pp. 1549-1556
-
-
Takai, H.1
Smogorzewska, A.2
de Lange, T.3
-
16
-
-
2442511752
-
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
-
Herbig U, Jobling WA, Chen BP, et al. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Mol Cell 2004 ; 14 : 501-13.
-
(2004)
Mol Cell
, vol.14
, pp. 501-513
-
-
Herbig, U.1
Jobling, W.A.2
Chen, B.P.3
-
17
-
-
14044255880
-
Activation of the DNA damage response by telomere attrition: A passage to cellular senescence
-
Reaper PM, di Fagagna F, Jackson SP. Activation of the DNA damage response by telomere attrition: a passage to cellular senescence. Cell Cycle 2004 ; 3 : 543-6.
-
(2004)
Cell Cycle
, vol.3
, pp. 543-546
-
-
Reaper, P.M.1
di Fagagna, F.2
Jackson, S.P.3
-
18
-
-
0037102234
-
Different telomere damage signaling pathways in human and mouse cells
-
Smogorzewska A, de Lange T. Different telomere damage signaling pathways in human and mouse cells. EMBO J 2002 ; 21 : 4338-48.
-
(2002)
EMBO J
, vol.21
, pp. 4338-4348
-
-
Smogorzewska, A.1
de Lange, T.2
-
19
-
-
40249100323
-
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
-
Young AP, Schlisio S, Minamishima YA, et al. VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400. Nat Cell Biol 2008 ; 10 : 361-9.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 361-369
-
-
Young, A.P.1
Schlisio, S.2
Minamishima, Y.A.3
-
20
-
-
23244447893
-
Tumour biology: Senescence in premalignant tumours
-
Collado M, Gil J, Efeyan A, et al. Tumour biology: senescence in premalignant tumours. Nature 2005 ; 436 : 642.
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
-
21
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen Z, Trotman LC, Shaffer D, et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 2005 ; 436 : 725-30.
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
-
22
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C, Vredeveld LC, Soengas MS, et al. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 2005 ; 436 : 720-4.
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.2
Soengas, M.S.3
-
23
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
Braig M, Lee S, Loddenkemper C, et al. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 2005 ; 436 : 660-5.
-
(2005)
Nature
, vol.436
, pp. 660-665
-
-
Braig, M.1
Lee, S.2
Loddenkemper, C.3
-
24
-
-
34247581288
-
Short telomeres limit tumor progression in vivo by inducing senescence
-
Feldser DM, Greider CW. Short telomeres limit tumor progression in vivo by inducing senescence. Cancer Cell 2007 ; 11 : 461-9.
-
(2007)
Cancer Cell
, vol.11
, pp. 461-469
-
-
Feldser, D.M.1
Greider, C.W.2
-
25
-
-
36248952723
-
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis
-
Guo X, Deng Y, Lin Y, et al. Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J 2007 ; 26 : 4709-19.
-
(2007)
EMBO J
, vol.26
, pp. 4709-4719
-
-
Guo, X.1
Deng, Y.2
Lin, Y.3
-
26
-
-
42449156430
-
Cibler les télomères pour forcer les cellules cancéreuses à rentrer en sénescence.
-
Londono-Vallejo A, Lenain C, Gilson E. Cibler les télomères pour forcer les cellules cancéreuses à rentrer en sénescence. Med Sci (Paris) 2008 ; 24 : 383-9.
-
(2008)
Med Sci (Paris)
, vol.24
, pp. 383-389
-
-
Londono-Vallejo, A.1
Lenain, C.2
Gilson, E.3
-
27
-
-
0037086268
-
DNA damage is able to induce senescence in tumor cells in vitro and in vivo
-
Te Poele RH, Okorokov AL, Jardine L, et al. DNA damage is able to induce senescence in tumor cells in vitro and in vivo. Cancer Res 2002 ; 62 : 1876-83.
-
(2002)
Cancer Res
, vol.62
, pp. 1876-1883
-
-
Te Poele, R.H.1
Okorokov, A.L.2
Jardine, L.3
-
28
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue W, Zender L, Miething C, et al. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007 ; 445 : 656-60.
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
-
29
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura A, Kirsch DG, McLaughlin ME, et al. Restoration of p53 function leads to tumour regression in vivo. Nature 2007 ; 445 : 61-5.
-
(2007)
Nature
, vol.445
, pp. 61-65
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
-
30
-
-
38849168162
-
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
-
Wajapeyee N, Serra RW, Zhu X, et al. Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 2008 ; 132 : 363-74.
-
(2008)
Cell
, vol.132
, pp. 363-374
-
-
Wajapeyee, N.1
Serra, R.W.2
Zhu, X.3
-
31
-
-
33746616991
-
Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
-
Kortlever RM, Higgins PJ, Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat Cell Biol 2006 ; 8 : 877-84.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 877-884
-
-
Kortlever, R.M.1
Higgins, P.J.2
Bernards, R.3
-
32
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
Kuilman T, Michaloglou C, Vredeveld LC, et al. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 2008 ; 133 : 1019-31.
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
-
33
-
-
44649120132
-
Chemokine signaling via the CXCR2 receptor reinforces senescence
-
Acosta JC, O'Loghlen A, Banito A, et al. Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 2008 ; 133 : 1006-18.
-
(2008)
Cell
, vol.133
, pp. 1006-1018
-
-
Acosta, J.C.1
O'Loghlen, A.2
Banito, A.3
-
34
-
-
0033215242
-
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
-
Olumi AF, Grossfeld GD, Hayward SW, et al. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999 ; 59 : 5002-11.
-
(1999)
Cancer Res
, vol.59
, pp. 5002-5011
-
-
Olumi, A.F.1
Grossfeld, G.D.2
Hayward, S.W.3
-
35
-
-
0041968702
-
Integrating epithelial cancer, aging stroma and cellular senescence
-
Krtolica A, Campisi J. Integrating epithelial cancer, aging stroma and cellular senescence. Adv Gerontol 2003 ; 11 : 109-16.
-
(2003)
Adv Gerontol
, vol.11
, pp. 109-116
-
-
Krtolica, A.1
Campisi, J.2
-
36
-
-
34249017255
-
Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: Stress-induced premature senescence does not increase effect
-
Liu D, Hornsby PJ. Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect. Neoplasia 2007 ; 9 : 418-26.
-
(2007)
Neoplasia
, vol.9
, pp. 418-426
-
-
Liu, D.1
Hornsby, P.J.2
-
37
-
-
34248197982
-
Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion
-
Liu D, Hornsby PJ. Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion. Cancer Res 2007 ; 67 : 3117-26.
-
(2007)
Cancer Res
, vol.67
, pp. 3117-3126
-
-
Liu, D.1
Hornsby, P.J.2
-
38
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005 ; 120 : 513-22.
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
39
-
-
38549116786
-
Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis
-
Dean JP, Nelson PS. Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis. Br J Cancer 2008 ; 98 : 245-9.
-
(2008)
Br J Cancer
, vol.98
, pp. 245-249
-
-
Dean, J.P.1
Nelson, P.S.2
-
40
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
Beausejour CM, Krtolica A, Galimi F, et al. Reversal of human cellular senescence: roles of the p53 and p16 pathways. EMBO J 2003 ; 22 : 4212-22.
-
(2003)
EMBO J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
-
41
-
-
0038342441
-
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
-
Sage J, Miller AL, Perez-Mancera PA, et al. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature 2003 ; 424 : 223-8.
-
(2003)
Nature
, vol.424
, pp. 223-228
-
-
Sage, J.1
Miller, A.L.2
Perez-Mancera, P.A.3
-
42
-
-
33750510904
-
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
-
Takahashi A, Ohtani N, Yamakoshi K, et al. Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence. Nat Cell Biol 2006 ; 8 : 1291-7.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1291-1297
-
-
Takahashi, A.1
Ohtani, N.2
Yamakoshi, K.3
-
43
-
-
33845299892
-
Stem cells, senescence, neosis and self-renewal in cancer
-
Rajaraman R, Guernsey DL, Rajaraman MM, Rajaraman SR. Stem cells, senescence, neosis and self-renewal in cancer. Cancer Cell Int 2006 ; 6 : 25.
-
(2006)
Cancer Cell Int
, vol.6
, pp. 25
-
-
Rajaraman, R.1
Guernsey, D.L.2
Rajaraman, M.M.3
Rajaraman, S.R.4
-
44
-
-
35348952095
-
Cancer: A matter of life cycle ?
-
Erenpreisa J, Cragg MS. Cancer: a matter of life cycle ? Cell Biol Int 2007 ; 31 : 1507-10.
-
(2007)
Cell Biol Int
, vol.31
, pp. 1507-1510
-
-
Erenpreisa, J.1
Cragg, M.S.2
-
45
-
-
18844403409
-
La sénescence : Une barrière télomé rique à l'immortalité ou une réponse cellulaire aux stress physiologiques ?
-
Gire V. La sénescence : une barrière télomé rique à l'immortalité ou une réponse cellulaire aux stress physiologiques ? Med Sci (Paris) 2005 ; 21 : 491-7
-
(2005)
Med Sci (Paris)
, vol.21
, pp. 491-497
-
-
Gire, V.1
-
46
-
-
33750039375
-
Régulation de p16INK4a, sénescence et oncogenèse.
-
Chien WW, Ffrench M. Régulation de p16INK4a, sénescence et oncogenèse. Med Sci (Paris) 2006 ; 22 : 865-71.
-
(2006)
Med Sci (Paris)
, vol.22
, pp. 865-871
-
-
Chien, W.W.1
Ffrench, M.2
-
47
-
-
34547133255
-
Réactivation de p53 dans les tumeurs : Une stratégie antitumorale prometteuse.
-
Toledo F, Bluteau O, Simeonova I. Réactivation de p53 dans les tumeurs : une stratégie antitumorale prometteuse. Med Sci (Paris) 2007 ; 23 : 565-7.
-
(2007)
Med Sci (Paris)
, vol.23
, pp. 565-567
-
-
Toledo, F.1
Bluteau, O.2
Simeonova, I.3
-
48
-
-
60149090173
-
Les cytokines préviennent les tumeurs via un mécanisme de sénescence cellulaire.
-
Gaumont-Leclerc MF, Ferbeyre G. Les cytokines préviennent les tumeurs via un mécanisme de sénescence cellulaire. Med Sci (Paris) 2009 ; 25 : 138-40.
-
(2009)
Med Sci (Paris)
, vol.25
, pp. 138-140
-
-
Gaumont-Leclerc, M.F.1
Ferbeyre, G.2
|