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Volumn 23, Issue 6-7, 2007, Pages 565-567

The activation of p53 in tumors: A promising strategy against cancer;Réactivation de p53 dans les tumeurs: Une stratégie antitumorale prometteuse

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; DNA; DOXYCYCLINE; ESTROGEN RECEPTOR; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P53; SHORT HAIRPIN RNA; TAMOXIFEN;

EID: 34547133255     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20072367565     Document Type: Note
Times cited : (4)

References (15)
  • 1
    • 33845270990 scopus 로고    scopus 로고
    • Regulating the p53 pathway: In vitro hypotheses, in vivo veritas
    • Toledo F, Wahl GM. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat Rev Cancer 2006 ; 6 : 909-23.
    • (2006) Nat Rev Cancer , vol.6 , pp. 909-923
    • Toledo, F.1    Wahl, G.M.2
  • 2
    • 33846148980 scopus 로고    scopus 로고
    • Outcomes of p53 activation: Spoilt for choice
    • Vousden KH. Outcomes of p53 activation: spoilt for choice. J Cell Sci 2006 ; 119 : 5015-20.
    • (2006) J Cell Sci , vol.119 , pp. 5015-5020
    • Vousden, K.H.1
  • 3
    • 33645465694 scopus 로고    scopus 로고
    • Controversial Chinese gene-therapy drug entering unfamiliar territory
    • Jia H. Controversial Chinese gene-therapy drug entering unfamiliar territory. Nat Rev Drug Discov 2006 ; 5 : 269-70.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 269-270
    • Jia, H.1
  • 4
    • 33646799132 scopus 로고    scopus 로고
    • Strategies for therapeutic targeting of the p53 pathway in cancer
    • Wiman KG. Strategies for therapeutic targeting of the p53 pathway in cancer. Cell Death Differ 2006 ; 13 : 921-6.
    • (2006) Cell Death Differ , vol.13 , pp. 921-926
    • Wiman, K.G.1
  • 5
    • 33845901313 scopus 로고    scopus 로고
    • MDM2 inhibitors for cancer therapy
    • Vassilev LT. MDM2 inhibitors for cancer therapy. Trends Mol Med 2007 ; 13 : 23-31.
    • (2007) Trends Mol Med , vol.13 , pp. 23-31
    • Vassilev, L.T.1
  • 6
    • 33747819484 scopus 로고    scopus 로고
    • ARF and p53: An unsettled case
    • Sherr CJ. Divorcing ARF and p53: an unsettled case. Nat Rev Cancer 2006 ; 6 : 663-73.
    • (2006) Nat Rev Cancer , vol.6 , pp. 663-673
    • Divorcing, S.C.J.1
  • 7
    • 33750590095 scopus 로고    scopus 로고
    • Inactivation of the p53 pathway in retinoblastoma
    • Laurie NA, Donovan SL, Shih CS, et al. Inactivation of the p53 pathway in retinoblastoma. Nature 2006 ; 444 : 61-6.
    • (2006) Nature , vol.444 , pp. 61-66
    • Laurie, N.A.1    Donovan, S.L.2    Shih, C.S.3
  • 8
    • 33645769536 scopus 로고    scopus 로고
    • A mouse p53 mutant lacking the proline rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network
    • Toledo F, Krummel KA, Lee CJ, et al. A mouse p53 mutant lacking the proline rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network. Cancer Cell 2006 ; 9 : 273-85.
    • (2006) Cancer Cell , vol.9 , pp. 273-285
    • Toledo, F.1    Krummel, K.A.2    Lee, C.J.3
  • 9
    • 33644778697 scopus 로고    scopus 로고
    • Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo
    • Francoz S, Froment P, Bogaerts S, et al. Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo. Proc Natl Acad Sci USA 2006 ; 103 : 3232-7.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 3232-3237
    • Francoz, S.1    Froment, P.2    Bogaerts, S.3
  • 10
    • 33746640122 scopus 로고    scopus 로고
    • Balancing Mdm2: A Daxx-HAUSP matter
    • Ronai Z. Balancing Mdm2: a Daxx-HAUSP matter. Nat Cell Biol 2006 ; 8 : 790-1.
    • (2006) Nat Cell Biol , vol.8 , pp. 790-791
    • Ronai, Z.1
  • 11
    • 33646343474 scopus 로고    scopus 로고
    • An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors
    • Brummelkamp TR, Fabius AW, Mullenders J, et al. An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors. Nat Chem Biol 2006 ; 2 : 202-6.
    • (2006) Nat Chem Biol , vol.2 , pp. 202-206
    • Brummelkamp, T.R.1    Fabius, A.W.2    Mullenders, J.3
  • 12
    • 33845185824 scopus 로고    scopus 로고
    • Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo
    • Ringshausen I, O'Shea C, Finch AJ, et al. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. Cancer Cell 2006 ; 10 : 501-14.
    • (2006) Cancer Cell , vol.10 , pp. 501-514
    • Ringshausen, I.1    O'Shea, C.2    Finch, A.J.3
  • 13
    • 33846899456 scopus 로고    scopus 로고
    • Restoration of p53 function leads to tumour regression in vivo
    • Ventura A, Kirsch DG, McLaughlin ME, et al. Restoration of p53 function leads to tumour regression in vivo. Nature 2007 ; 445 : 661-5.
    • (2007) Nature , vol.445 , pp. 661-665
    • Ventura, A.1    Kirsch, D.G.2    McLaughlin, M.E.3
  • 14
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • Xue W, Zender L, Miething C, et al. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007 ; 445 : 656-60.
    • (2007) Nature , vol.445 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3
  • 15
    • 33845611951 scopus 로고    scopus 로고
    • Modeling the therapeutic efficacy of p53 restoration in tumors
    • Martins CP, Brown-Swigart L, Evan GI. Modeling the therapeutic efficacy of p53 restoration in tumors. Cell 2006 ; 127 : 1323-34.
    • (2006) Cell , vol.127 , pp. 1323-1334
    • Martins, C.P.1    Brown-Swigart, L.2    Evan, G.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.