Docking studies suggest ligand-specific δ-opioid receptor conformations

Journal of Molecular Modeling

Volumn 15, Issue 3, 2009, Pages 267-280

  Micovic, Vuk ^a   Ivanovic, Milovan D ^b   Dosen Micovic, Ljiljana ^b,c  

^a Institute of General and Physical Chemistry   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c Institute for Chemistry   (Serbia)

Author keywords

Delta opioid receptor; Docking simulation; Ligand receptor interactions; Molecular modeling

Indexed keywords

1,2,3,4,4A,5,12,12AALPHA OCTAHYDRO 4AALPHA (3 HYDROXYPHENYL) 2 METHYLQUINOLINO[2,3 G]ISOQUINOLINE; 3 (2 CYCLOPROPYLMETHYL 1,2,3,4,5,6,11,11A OCTAHYDROPYRIDOL[4,3 B]CARBAZOL 4A YL)PHENOL; 3 HYDROXY 6,7 DIDEHYDRO 4,5ALPHA EPOXY 17 METHYL 14BETA (3 METHYL)BUTYL 6,7,2',3' INDOMORPHINAN; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; 6 ETHYL 8A (3 HYDROXYPHENYL) 3 METHYL 4,4A,5,6,7,8,8A,9 OCTAHYDRO 1 PYRROLO[2,3 G]ISOQUINOLINE 2 CARNOXYLIC ACID DIETHYLAMINE; 7 BENZYLIDENENALTREXONE; 7 SPIROINDANYLOXYMORPHONE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTA OPIATE RECEPTOR ANTAGONIST; MEFENTANYL; MEFENTANYL ISOTHIOCYANATE; NALTRIBEN; NALTRINDOLE; OPIATE AGONIST; OPIATE ANTAGONIST; SB 206848; SB 219825; SNC 67; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING ENERGY; BINDING SITE; COMPUTER SIMULATION; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; ENERGY; LIGAND BINDING; MOLECULAR DOCKING; POINT MUTATION; PRIORITY JOURNAL;

BINDING SITES; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECEPTORS, OPIOID, DELTA; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 59149102761     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-008-0396-7     Document Type: Article

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