Synthesis and evaluation of 4-(N,N-diarylamino)piperidines with high selectivity to the δ-opioid receptor: A combined 3D-QSAR and ligand docking study

Drug Design and Discovery

Volumn 17, Issue 1, 2000, Pages 34-50

  Podlogar, Brent L ^b   Poda, Gennady I ^c   Demeter, David A ^d   Zhang, Sui Po ^a   Carson, John R ^a   Neilson, Lou Anne ^a   Reitz, Allen B ^a   Ferguson, David M ^c  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b BAYER CORPORATION   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d DOW AGROSCIENCES LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; DELTA OPIATE RECEPTOR; MU OPIATE RECEPTOR; PIPERIDINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BINDING SITE; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; LIGAND BINDING; MALE; MOLECULAR DYNAMICS; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; LIGANDS; MALE; MOLECULAR SEQUENCE DATA; PIPERIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; RATS, WISTAR; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU;

EID: 0034125253     PISSN: 10559612     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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