Analgesic activity and selectivity of isothiocyanate derivatives of fentanyl analogs for opioid receptors

Life Sciences

Volumn 65, Issue 15, 1999, Pages 1589-1595

  Bi Yi, Chen ^a,b   Wen Qiao, Jin ^a,b   Jie, Chen ^a,b   Xin Jian, Chen ^a,b   You Cheng, Zhu ^a,b   Zhi Qiang, Chi ^a,b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

Author keywords

Analgesia; Binding selectivity; Bioassay; Fentanyl analogs; Isothiocyanate derivatives; Opioid receptors

Indexed keywords

ANTINOCICEPTIVE AGENT; BETA HYDROXYMEFENTANYL; CARFENTANIL; DELTA OPIATE RECEPTOR; FENTANYL DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; MEFENTANYL; NALOXONE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL TISSUE; ARTICLE; CHEMICAL MODIFICATION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG INHIBITION; DRUG STRUCTURE; EVOKED MUSCLE RESPONSE; INHIBITION KINETICS; MOUSE; NONHUMAN; RECEPTOR AFFINITY; RECEPTOR BINDING;

AMIDES; ANALGESICS, OPIOID; ANIMALS; FENTANYL; ISOTHIOCYANATES; MALE; MICE; MUSCLE CONTRACTION; NOCICEPTORS; PAIN MEASUREMENT; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; VAS DEFERENS;

ANIMALIA;

EID: 0033520501     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(99)00404-X     Document Type: Article

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