Constitutive activation of the δ opioid receptor by mutations in transmembrane domains III and VII

Journal of Biological Chemistry

Volumn 274, Issue 26, 1999, Pages 18574-18581

  Befort, Katia ^a   Zilliox, Christelle ^a   Filliol, Dominique ^a   Yue, ShiYi ^b   Kieffer, Brigitte L ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b Astra Research Centre Montreal   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; BREMAZOCINE; DELTA OPIATE RECEPTOR; DELTORPHIN; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE;

ANIMAL CELL; ARTICLE; CHEMICAL BOND; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY;

AMINO ACID SUBSTITUTION; ANIMALS; CELL MEMBRANE; COS CELLS; ENKEPHALIN, LEUCINE-2-ALANINE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); LIGANDS; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NALTREXONE; NARCOTIC ANTAGONISTS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, OPIOID, DELTA; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0033603318     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.26.18574     Document Type: Article

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