Skin application of ketoprofen systemically suppresses contact hypersensitivity by inducing CD4+ CD25+ regulatory T cells

Journal of Dermatological Science

Volumn 53, Issue 3, 2009, Pages 216-221

  Atarashi, Kenji ^a,b   Mori, Tomoko ^a   Yoshiki, Ryutaro ^a   Kabashima, Kenji ^a   Kuma, Hidekazu ^b   Tokura, Yoshiki ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b HISAMITSU PHARMACEUTICAL CO INC   (Japan)

Author keywords

Contact hypersensitivity; Immunosupression; Ketoprofen; Regulatory T cell

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; HAPTEN; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; KETOPROFEN; MESSENGER RNA; OXAZOLONE; PICRYL CHLORIDE; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL ACTIVITY; CELL TRANSFER; CONTACT ALLERGY; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; IMMUNOSUPPRESSIVE TREATMENT; LYMPH NODE CELL; MOUSE; NONHUMAN; PHOTOTHERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SKIN SENSITIZATION;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD; ANTIGENS, CD4; DERMATITIS, CONTACT; DINOPROSTONE; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HAPTENS; INTERLEUKIN-10; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; KETOPROFEN; LYMPH NODES; MICE; MICE, INBRED BALB C; OXAZOLONE; PICRYL CHLORIDE; T-LYMPHOCYTES, REGULATORY;

EID: 58649090228     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2008.10.011     Document Type: Article

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