-
1
-
-
47749141560
-
ATR: An essential regulator of genome integrity
-
Cimprich KA and Cortez D. ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol 2008; 9:616-27.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
2
-
-
34247251276
-
building a trigger of ATR-mediated DNA damage response
-
and double-stranded DNA
-
Zou L. Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response. Genes Dev 2007; 21:879-85.
-
(2007)
Genes Dev
, vol.21
, pp. 879-885
-
-
Single, Z.L.1
-
3
-
-
33746775293
-
Translesion synthesis in mammalian cells
-
Lehmann AR. Translesion synthesis in mammalian cells. Exp Cell Res 2006; 312:2673-6.
-
(2006)
Exp Cell Res
, vol.312
, pp. 2673-2676
-
-
Lehmann, A.R.1
-
4
-
-
2442417331
-
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: A possible mechanism for the polymerase switch in response to DNA damage
-
Kannouche PL, Wing J and Lehmann AR. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol Cell 2004; 14:491-500.
-
(2004)
Mol Cell
, vol.14
, pp. 491-500
-
-
Kannouche, P.L.1
Wing, J.2
Lehmann, A.R.3
-
5
-
-
6344288785
-
Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination
-
Watanabe K, et al. Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. Embo J 2004; 23:3886-96.
-
(2004)
Embo J
, vol.23
, pp. 3886-3896
-
-
Watanabe, K.1
-
6
-
-
33646234739
-
Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest
-
Bi X, et al. Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest. Mol Cell Biol 2006; 26:3527-40.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3527-3540
-
-
Bi, X.1
-
7
-
-
43249094413
-
Chk1 and Claspin potentiate PCNA ubiquitination
-
Yang XH, Shiotani B, Classon M and Zou L. Chk1 and Claspin potentiate PCNA ubiquitination. Genes Dev 2008; 22:1147-52.
-
(2008)
Genes Dev
, vol.22
, pp. 1147-1152
-
-
Yang, X.H.1
Shiotani, B.2
Classon, M.3
Zou, L.4
-
8
-
-
29444454665
-
Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1
-
Garg P and Burgers PM. Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1. Proc Natl Acad Sci USA 2005; 102:18361-6.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18361-18366
-
-
Garg, P.1
Burgers, P.M.2
-
9
-
-
33645708319
-
Regulation of monoubiquitinated PCNA by DUB autocleavage
-
Huang TT, et al. Regulation of monoubiquitinated PCNA by DUB autocleavage. Nat Cell Biol 2006; 8:339-47.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 339-347
-
-
Huang, T.T.1
-
10
-
-
29144501653
-
Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts
-
Leach CA and Michael WM. Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts. J Cell Biol 2005; 171:947-54.
-
(2005)
J Cell Biol
, vol.171
, pp. 947-954
-
-
Leach, C.A.1
Michael, W.M.2
-
11
-
-
33745629358
-
Postreplication repair and PCNA modification in Schizosaccharomyces pombe
-
Frampton J, et al. Postreplication repair and PCNA modification in Schizosaccharomyces pombe. Mol Biol Cell 2006; 17:2976-85.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 2976-2985
-
-
Frampton, J.1
-
12
-
-
33845959940
-
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities
-
Chang DJ, Lupardus PJ and Cimprich KA. Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities. J Biol Chem 2006; 281:32081-8.
-
(2006)
J Biol Chem
, vol.281
, pp. 32081-32088
-
-
Chang, D.J.1
Lupardus, P.J.2
Cimprich, K.A.3
-
13
-
-
18244371925
-
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
-
Byun TS, Pacek M, Yee MC, Walter JC and Cimprich KA. Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev 2005; 19:1040-52.
-
(2005)
Genes Dev
, vol.19
, pp. 1040-1052
-
-
Byun, T.S.1
Pacek, M.2
Yee, M.C.3
Walter, J.C.4
Cimprich, K.A.5
-
14
-
-
0037178740
-
Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects
-
Sogo JM, Lopes M and Foiani M. Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects. Science 2002; 297:599-602.
-
(2002)
Science
, vol.297
, pp. 599-602
-
-
Sogo, J.M.1
Lopes, M.2
Foiani, M.3
-
15
-
-
29544437558
-
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
-
Lopes M, Foiani M and Sogo JM. Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol Cell 2006; 21:15-27.
-
(2006)
Mol Cell
, vol.21
, pp. 15-27
-
-
Lopes, M.1
Foiani, M.2
Sogo, J.M.3
-
16
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou L and Elledge SJ. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 2003; 300:1542-8.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
17
-
-
31444452984
-
ATRIP associates with replication protein A-coated ssDNA through multiple interactions
-
Namiki Y and Zou L. ATRIP associates with replication protein A-coated ssDNA through multiple interactions. Proc Natl Acad Sci USA 2006; 103:580-5.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 580-585
-
-
Namiki, Y.1
Zou, L.2
-
18
-
-
41149165416
-
Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks
-
Tsuji Y, et al. Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks. Genes Cells 2008; 13:343-54.
-
(2008)
Genes Cells
, vol.13
, pp. 343-354
-
-
Tsuji, Y.1
-
19
-
-
55849091416
-
Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells
-
Niimi A, et al. Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proc Natl Acad Sci USA 2008; 105:16125-30.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16125-16130
-
-
Niimi, A.1
-
20
-
-
40649097306
-
Activation of ubiquitindependent DNA damage bypass is mediated by replication protein a
-
Davies AA, Huttner D, Daigaku Y, Chen S and Ulrich HD. Activation of ubiquitindependent DNA damage bypass is mediated by replication protein a. Mol Cell 2008; 29:625-36.
-
(2008)
Mol Cell
, vol.29
, pp. 625-636
-
-
Davies, A.A.1
Huttner, D.2
Daigaku, Y.3
Chen, S.4
Ulrich, H.D.5
-
21
-
-
0345564858
-
Replication protein A-mediated recruitment and activation of Rad17 complexes
-
Zou L, Liu D and Elledge SJ. Replication protein A-mediated recruitment and activation of Rad17 complexes. Proc Natl Acad Sci USA 2003; 100:13827-32.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13827-13832
-
-
Zou, L.1
Liu, D.2
Elledge, S.J.3
-
22
-
-
0037080675
-
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
-
Zou L, Cortez D and Elledge SJ. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev 2002; 16:198-208.
-
(2002)
Genes Dev
, vol.16
, pp. 198-208
-
-
Zou, L.1
Cortez, D.2
Elledge, S.J.3
-
23
-
-
33644757806
-
TopBP1 activates the ATR-ATRIP complex
-
Kumagai A, Lee J, Yoo HY and Dunphy WG. TopBP1 activates the ATR-ATRIP complex. Cell 2006; 124:943-55.
-
(2006)
Cell
, vol.124
, pp. 943-955
-
-
Kumagai, A.1
Lee, J.2
Yoo, H.Y.3
Dunphy, W.G.4
-
24
-
-
43049160831
-
Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp
-
Fu Y, et al. Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp. Cell 2008; 133:601-11.
-
(2008)
Cell
, vol.133
, pp. 601-611
-
-
Fu, Y.1
-
25
-
-
47749148089
-
A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function
-
Scorah J, et al. A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function. J Biol Chem 2008; 283:17250-9.
-
(2008)
J Biol Chem
, vol.283
, pp. 17250-17259
-
-
Scorah, J.1
-
26
-
-
33846327177
-
Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors
-
Gotter AL, Suppa C and Emanuel BS. Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors. J Mol Biol 2007; 366:36-52.
-
(2007)
J Mol Biol
, vol.366
, pp. 36-52
-
-
Gotter, A.L.1
Suppa, C.2
Emanuel, B.S.3
-
27
-
-
34147201111
-
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement
-
Unsal-Kacmaz K, et al. The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol 2007; 27:3131-42.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3131-3142
-
-
Unsal-Kacmaz, K.1
-
28
-
-
0042865938
-
S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex
-
Katou Y, et al. S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex. Nature 2003; 424:1078-83.
-
(2003)
Nature
, vol.424
, pp. 1078-1083
-
-
Katou, Y.1
-
29
-
-
53149135030
-
Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint
-
Lou H, et al. Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Mol Cell 2008; 32:106-17.
-
(2008)
Mol Cell
, vol.32
, pp. 106-117
-
-
Lou, H.1
-
30
-
-
33746408535
-
Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress
-
Wang X, et al. Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell 2006; 23:331-41.
-
(2006)
Mol Cell
, vol.23
, pp. 331-341
-
-
Wang, X.1
-
31
-
-
33746047485
-
Chk1 is required to maintain claspin stability
-
Chini CC, Wood J and Chen J. Chk1 is required to maintain claspin stability. Oncogene 2006; 25:4165-71.
-
(2006)
Oncogene
, vol.25
, pp. 4165-4171
-
-
Chini, C.C.1
Wood, J.2
Chen, J.3
-
32
-
-
33645825609
-
Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase
-
Petermann E, et al. Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase. Mol Cell Biol 2006; 26:3319-26.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3319-3326
-
-
Petermann, E.1
-
33
-
-
10744230485
-
Global mapping of the yeast genetic interaction network
-
Tong AH, et al. Global mapping of the yeast genetic interaction network. Science 2004; 303:808-13.
-
(2004)
Science
, vol.303
, pp. 808-813
-
-
Tong, A.H.1
-
34
-
-
0038506000
-
Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53
-
Osborn AJ and Elledge SJ. Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. Genes Dev 2003; 17:1755-67.
-
(2003)
Genes Dev
, vol.17
, pp. 1755-1767
-
-
Osborn, A.J.1
Elledge, S.J.2
-
35
-
-
3543031002
-
Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage
-
Xu H, Boone C and Klein HL. Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage. Mol Cell Biol 2004; 24:7082-90.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7082-7090
-
-
Xu, H.1
Boone, C.2
Klein, H.L.3
-
36
-
-
24044552287
-
Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53
-
Tourriere H, Versini G, Cordon-Preciado V, Alabert C and Pasero P. Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53. Mol Cell 2005; 19:699-706.
-
(2005)
Mol Cell
, vol.19
, pp. 699-706
-
-
Tourriere, H.1
Versini, G.2
Cordon-Preciado, V.3
Alabert, C.4
Pasero, P.5
-
37
-
-
23944507608
-
Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork
-
Calzada A, Hodgson B, Kanemaki M, Bueno A and Labib K. Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev 2005; 19:1905-19.
-
(2005)
Genes Dev
, vol.19
, pp. 1905-1919
-
-
Calzada, A.1
Hodgson, B.2
Kanemaki, M.3
Bueno, A.4
Labib, K.5
-
38
-
-
24044463869
-
Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae
-
Szyjka SJ, Viggiani CJ and Aparicio OM. Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae. Mol Cell 2005; 19:691-7.
-
(2005)
Mol Cell
, vol.19
, pp. 691-697
-
-
Szyjka, S.J.1
Viggiani, C.J.2
Aparicio, O.M.3
-
39
-
-
34948812991
-
Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase
-
Hodgson B, Calzada A and Labib K. Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase. Mol Biol Cell 2007; 18:3894-902.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 3894-3902
-
-
Hodgson, B.1
Calzada, A.2
Labib, K.3
-
40
-
-
32244447176
-
The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae
-
Mohanty BK, Bairwa NK and Bastia D. The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 2006; 103:897-902.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 897-902
-
-
Mohanty, B.K.1
Bairwa, N.K.2
Bastia, D.3
-
41
-
-
48749128133
-
Claspin promotes normal replication fork rates in human cells
-
Petermann E, Helleday T and Caldecott KW. Claspin promotes normal replication fork rates in human cells. Mol Biol Cell 2008; 19:2373-8.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2373-2378
-
-
Petermann, E.1
Helleday, T.2
Caldecott, K.W.3
-
42
-
-
34047261441
-
Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint
-
Yoshizawa-Sugata N and Masai H. Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint. J Biol Chem 2007; 282:2729-40.
-
(2007)
J Biol Chem
, vol.282
, pp. 2729-2740
-
-
Yoshizawa-Sugata, N.1
Masai, H.2
-
43
-
-
33845320139
-
Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function
-
Chou DM and Elledge SJ. Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. Proc Natl Acad Sci USA 2006; 103:18143-7.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18143-18147
-
-
Chou, D.M.1
Elledge, S.J.2
|