Free radical trapping as a therapeutic approach to neuroprotection in stroke: Experimental and clinical studies with NXY-059 and free radical scavengers

Current Drug Targets: CNS and Neurological Disorders

Volumn 4, Issue 2, 2005, Pages 109-118

  Green, A Richard ^a   Ashwood, Tim ^b  

^a ASTRAZENECA   (United Kingdom)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Cerebral ischemia; Ebselen; Edaravone; Free radicals; Hemorrhagic stroke; Ischemic stroke; NXY 059; Stroke; Subarachnoid hemorrhage; Tirilazad

Indexed keywords

DISUFENTON SODIUM; EBSELEN; FREE RADICAL; NORPHENAZONE; PHENYTOIN; TIRILAZAD;

ANTIOXIDANT ACTIVITY; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; DISEASE SEVERITY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; DRUG RESPONSE; DRUG TOLERABILITY; GLASGOW COMA SCALE; HUMAN; INTRACRANIAL PRESSURE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; REVIEW; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STEADY STATE; STROKE; SUBARACHNOID HEMORRHAGE;

EID: 18044379722     PISSN: 1568007X     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568007053544156     Document Type: Review

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