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Volumn 58, Issue , 2007, Pages 89-106

Acute ischemic stroke: Overview of recent therapeutic developments

Author keywords

Clot retrieval; Hemorrhage; Intracranial clot lysis; Perfusion mismatch; Thrombolysis

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ALTEPLASE; CITICOLINE; DISUFENTON SODIUM; GADOLINIUM; HEPARIN; HEPARINOID; LOW MOLECULAR WEIGHT HEPARIN; PLACEBO; PROUROKINASE; FIBRINOLYTIC AGENT; NEUROPROTECTIVE AGENT; TISSUE PLASMINOGEN ACTIVATOR;

EID: 34047103073     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.med.58.070605.115306     Document Type: Review
Times cited : (40)

References (62)
  • 2
    • 0034793573 scopus 로고    scopus 로고
    • Trend of stroke hospitalization, United States, 1988-1997
    • Fang J, Alderman MH. 2001. Trend of stroke hospitalization, United States, 1988-1997. Stroke 32:2213-20
    • (2001) Stroke , vol.32 , pp. 2213-2220
    • Fang, J.1    Alderman, M.H.2
  • 3
    • 16844376360 scopus 로고    scopus 로고
    • Guidelines for the early management of patients with ischemic stroke: 2005 guidelines update. A scientific statement from the Stroke Council of the American Heart Association/American Stroke Association
    • Adams H, Adams R, Del Zoppo G, Goldstein LB. 2005. Guidelines for the early management of patients with ischemic stroke: 2005 guidelines update. A scientific statement from the Stroke Council of the American Heart Association/American Stroke Association. Stroke 36:916-21
    • (2005) Stroke , vol.36 , pp. 916-921
    • Adams, H.1    Adams, R.2    Del Zoppo, G.3    Goldstein, L.B.4
  • 4
    • 0037383268 scopus 로고    scopus 로고
    • Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association
    • Adams HP, Adams RJ, Brott T, et al. 2003. Guidelines for the early management of patients with ischemic stroke: a scientific statement from the Stroke Council of the American Stroke Association. Stroke 34:1056-83
    • (2003) Stroke , vol.34 , pp. 1056-1083
    • Adams, H.P.1    Adams, R.J.2    Brott, T.3
  • 5
    • 0035105629 scopus 로고    scopus 로고
    • Perfusion thresholds in human cerebral ischemia: Historical perspective and therapeutic implications
    • Baron JC. 2001. Perfusion thresholds in human cerebral ischemia: historical perspective and therapeutic implications. Cerebrovasc. Dis. 11(Suppl. 1):2-8
    • (2001) Cerebrovasc. Dis , vol.11 , Issue.SUPPL. 1 , pp. 2-8
    • Baron, J.C.1
  • 6
    • 18244365100 scopus 로고    scopus 로고
    • Transient ischemic attack with infarction: A unique syndrome?
    • Ay H, Koroshetz WJ, Benner T, et al. 2005. Transient ischemic attack with infarction: a unique syndrome? Ann. Neurol. 57:679-86
    • (2005) Ann. Neurol , vol.57 , pp. 679-686
    • Ay, H.1    Koroshetz, W.J.2    Benner, T.3
  • 7
    • 0033485522 scopus 로고    scopus 로고
    • Recombinant tissue plasminogen activator (Alteplase) for ischemic stroke within 3 to 5 hours after symptom onset. The ATLANTIS Study: A randomized controlled trial
    • Clark W, Wissman S, Albers GW, et al. 1999. Recombinant tissue plasminogen activator (Alteplase) for ischemic stroke within 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. JAMA 282:2019-26
    • (1999) JAMA , vol.282 , pp. 2019-2026
    • Clark, W.1    Wissman, S.2    Albers, G.W.3
  • 8
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • National Institute of Neurological Disorders and Stroke, rt-PA Stroke Study Group
    • National Institute of Neurological Disorders and Stroke, rt-PA Stroke Study Group. 1995. Tissue plasminogen activator for acute ischemic stroke. N. Engl. J. Med. 333:1581-87
    • (1995) N. Engl. J. Med , vol.333 , pp. 1581-1587
  • 9
    • 3042637490 scopus 로고    scopus 로고
    • Stroke care delivery in institutions participating in the registry of the Canadian Stroke Network
    • for the investigators of the registry of the Canadian Stroke Network
    • Kapral MK, Laupacis A, Phillips SJ, et al. for the investigators of the registry of the Canadian Stroke Network. 2004. Stroke care delivery in institutions participating in the registry of the Canadian Stroke Network. Stroke 35:1756-62
    • (2004) Stroke , vol.35 , pp. 1756-1762
    • Kapral, M.K.1    Laupacis, A.2    Phillips, S.J.3
  • 10
    • 33746876034 scopus 로고    scopus 로고
    • Thrombolytic therapy in acute ischemic stroke in Asia. The first prospective evaluation
    • E-pub ahead of print. doi:10.1016/j.clineuro.2005.09.008
    • Suwanwela NC, Phanthumchinda K, Likitjaroen Y. 2005. Thrombolytic therapy in acute ischemic stroke in Asia. The first prospective evaluation. Clin. Neurol. Neurosurg. E-pub ahead of print. doi:10.1016/j.clineuro.2005.09.008
    • (2005) Clin. Neurol. Neurosurg
    • Suwanwela, N.C.1    Phanthumchinda, K.2    Likitjaroen, Y.3
  • 11
    • 33644861844 scopus 로고    scopus 로고
    • Factors associated with inhospital mortality after administration of thrombolysis in acute ischemic stroke patients: An analysis of the Nationwide Inpatient Sample 1999-2002
    • Bateman BT, Schumacher HC, Boden-Albala B, et al. 2006. Factors associated with inhospital mortality after administration of thrombolysis in acute ischemic stroke patients: an analysis of the Nationwide Inpatient Sample 1999-2002. Stroke 37:440-46
    • (2006) Stroke , vol.37 , pp. 440-446
    • Bateman, B.T.1    Schumacher, H.C.2    Boden-Albala, B.3
  • 12
    • 0029050323 scopus 로고
    • Intravenous thrombolysis with recombinant tissue plasminogen activator for acute ischemic stroke
    • Hacke W, Kaste M, Fieschi C, et al. 1995. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute ischemic stroke. JAMA 274:1017-25
    • (1995) JAMA , vol.274 , pp. 1017-1025
    • Hacke, W.1    Kaste, M.2    Fieschi, C.3
  • 13
    • 1542315556 scopus 로고    scopus 로고
    • Association of outcome with early stroke treatment: Pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials
    • Hacke W, Donnan G, Fieschi C, et al. 2004. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 363:768-74
    • (2004) Lancet , vol.363 , pp. 768-774
    • Hacke, W.1    Donnan, G.2    Fieschi, C.3
  • 14
    • 27644586324 scopus 로고    scopus 로고
    • Outcomes in patients who do not receive tPA because of mild or improving ischemic stroke
    • Smith EE, Abdullah A, Petkovska I, et al. 2005. Outcomes in patients who do not receive tPA because of mild or improving ischemic stroke. Stroke 36:2497-99
    • (2005) Stroke , vol.36 , pp. 2497-2499
    • Smith, E.E.1    Abdullah, A.2    Petkovska, I.3
  • 15
    • 34248226697 scopus 로고    scopus 로고
    • Katzin IL, Hammer MD, Furlan AJ, et al., Cleveland Clinic Health System Stroke Quality Improvement Team. 2003. Quality improvement and tissue type plasminogen activator for acute ischemic stroke: a Cleveland update. Stroke 34:2847-50
    • Katzin IL, Hammer MD, Furlan AJ, et al., Cleveland Clinic Health System Stroke Quality Improvement Team. 2003. Quality improvement and tissue type plasminogen activator for acute ischemic stroke: a Cleveland update. Stroke 34:2847-50
  • 16
    • 7444263622 scopus 로고    scopus 로고
    • Virtual telestroke support for the emergency department evaluation of acute stroke
    • Schwamm LH, Rosenthal ES, Hirschberg A, et al. 2004. Virtual telestroke support for the emergency department evaluation of acute stroke. Acad. Emer. Med. 11:1193-97
    • (2004) Acad. Emer. Med , vol.11 , pp. 1193-1197
    • Schwamm, L.H.1    Rosenthal, E.S.2    Hirschberg, A.3
  • 17
    • 24944454194 scopus 로고    scopus 로고
    • Stroke units, tissue plasminogen activator, aspirin and neuroprotection: Which stroke intervention could provide the greatest community benefit?
    • Gilligan AK, Thrift AG, Sturm JW, et al. 2005. Stroke units, tissue plasminogen activator, aspirin and neuroprotection: Which stroke intervention could provide the greatest community benefit? Cerebrovasc. Dis. 20:239-44
    • (2005) Cerebrovasc. Dis , vol.20 , pp. 239-244
    • Gilligan, A.K.1    Thrift, A.G.2    Sturm, J.W.3
  • 18
    • 26944503541 scopus 로고    scopus 로고
    • Early assessment by a mobile stroke team: A randomized controlled trial
    • Dey P, Woodman M, Gibbs A, et al. 2005. Early assessment by a mobile stroke team: a randomized controlled trial. Age and Ageing. 34:331-38
    • (2005) Age and Ageing , vol.34 , pp. 331-338
    • Dey, P.1    Woodman, M.2    Gibbs, A.3
  • 19
    • 84891700848 scopus 로고    scopus 로고
    • A randomized controlled comparison of alternative strategies in stroke care
    • Kalra L, Evans A, Perez L, et al. 2005. A randomized controlled comparison of alternative strategies in stroke care. Health Technol. Assess. 9:1-94
    • (2005) Health Technol. Assess , vol.9 , pp. 1-94
    • Kalra, L.1    Evans, A.2    Perez, L.3
  • 20
    • 13444271915 scopus 로고    scopus 로고
    • Early supported discharge services for stroke patients: A meta-analysis of individual patients' data
    • Langhorne P, Taylor G, Murray G, et al. 2005. Early supported discharge services for stroke patients: a meta-analysis of individual patients' data. Lancet 363:501-6
    • (2005) Lancet , vol.363 , pp. 501-506
    • Langhorne, P.1    Taylor, G.2    Murray, G.3
  • 21
    • 0026759412 scopus 로고
    • Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke
    • Del Zoppo GJ, Poeck K, Pessin MS, et al. 1992. Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke. Ann. Neurol. 32:78-86
    • (1992) Ann. Neurol , vol.32 , pp. 78-86
    • Del Zoppo, G.J.1    Poeck, K.2    Pessin, M.S.3
  • 22
    • 8644230974 scopus 로고    scopus 로고
    • Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke
    • for the CLOTBUST Investigators
    • Alexandrov AV, Molina CA, Grotta JC, et al., for the CLOTBUST Investigators. 2004. Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N. Engl. J. Med. 351:2170-78
    • (2004) N. Engl. J. Med , vol.351 , pp. 2170-2178
    • Alexandrov, A.V.1    Molina, C.A.2    Grotta, J.C.3
  • 23
    • 0037167558 scopus 로고    scopus 로고
    • Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator
    • Alexandrov AV, Grotta JC. 2002. Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator. Neurology 58:862-67
    • (2002) Neurology , vol.58 , pp. 862-867
    • Alexandrov, A.V.1    Grotta, J.C.2
  • 24
    • 33644851343 scopus 로고    scopus 로고
    • Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator
    • Molina CA, Ribo M, Rubiera M, et al. 2006. Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator. Stroke 37(2):425-29
    • (2006) Stroke , vol.37 , Issue.2 , pp. 425-429
    • Molina, C.A.1    Ribo, M.2    Rubiera, M.3
  • 25
    • 22044441701 scopus 로고    scopus 로고
    • Transcranial low-frequency ultrasound mediated thrombolysis in brain ischemia: Increased risk of hemorrhage with combined ultrasound and tissue plasminogen activator: results of a phase II clinical trial
    • Daffertshofer M, Gass A, Ringleb P, et al. 2005. Transcranial low-frequency ultrasound mediated thrombolysis in brain ischemia: increased risk of hemorrhage with combined ultrasound and tissue plasminogen activator: results of a phase II clinical trial. Stroke 36:1441-46
    • (2005) Stroke , vol.36 , pp. 1441-1446
    • Daffertshofer, M.1    Gass, A.2    Ringleb, P.3
  • 26
    • 0023711347 scopus 로고
    • Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease
    • Hacke W, Zeumer H, Ferbert A, et al. 1988. Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease. Stroke 19:1216-22
    • (1988) Stroke , vol.19 , pp. 1216-1222
    • Hacke, W.1    Zeumer, H.2    Ferbert, A.3
  • 27
    • 0033486107 scopus 로고    scopus 로고
    • Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: A randomized controlled trial. Prolyse in acute cerebral thromboembolism
    • Furlan A, Higashida R, Wechsler L, et al. 1999. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in acute cerebral thromboembolism. JAMA 282:2003-11
    • (1999) JAMA , vol.282 , pp. 2003-2011
    • Furlan, A.1    Higashida, R.2    Wechsler, L.3
  • 28
    • 0036480718 scopus 로고    scopus 로고
    • Endovascular administration after intravenous infusion of thrombolytic agents for the treatment of patients with acute ischemic strokes
    • Suarez JI, Zaidat OO, Sunshine JL, et al. 2002. Endovascular administration after intravenous infusion of thrombolytic agents for the treatment of patients with acute ischemic strokes. Neurosurgery 50:251-60
    • (2002) Neurosurgery , vol.50 , pp. 251-260
    • Suarez, J.I.1    Zaidat, O.O.2    Sunshine, J.L.3
  • 29
    • 0030698279 scopus 로고    scopus 로고
    • Pharmacologic elevation of blood pressure in acute stroke: Clinical effects and safety
    • Rordorf G, Cramer S, Efird JT, et al. 1997. Pharmacologic elevation of blood pressure in acute stroke: clinical effects and safety. Stroke 28:2133-38
    • (1997) Stroke , vol.28 , pp. 2133-2138
    • Rordorf, G.1    Cramer, S.2    Efird, J.T.3
  • 30
    • 0842310794 scopus 로고    scopus 로고
    • MRI improves detection of intracerebral hemorrhage over CT following intra-arterial thrombolysis
    • Greer DM, Lev MH, Cullen S, et al. 2004. MRI improves detection of intracerebral hemorrhage over CT following intra-arterial thrombolysis. Stroke 35(2):491-95
    • (2004) Stroke , vol.35 , Issue.2 , pp. 491-495
    • Greer, D.M.1    Lev, M.H.2    Cullen, S.3
  • 31
    • 0032710461 scopus 로고    scopus 로고
    • Combined intravenous and intraarterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial
    • Lewandowski CA, Frankel M, Tomsick TA, et al. 1999. Combined intravenous and intraarterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial. Stroke 30:2598-605
    • (1999) Stroke , vol.30 , pp. 2598-2605
    • Lewandowski, C.A.1    Frankel, M.2    Tomsick, T.A.3
  • 32
    • 1842418772 scopus 로고    scopus 로고
    • Combined intravenous and intra-arterial recanalization for acute ischemic stroke: The Interventional Management of Stroke Study
    • The IMS Study Investigators
    • The IMS Study Investigators. 2004. Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study. Stroke 35:904-11
    • (2004) Stroke , vol.35 , pp. 904-911
  • 33
    • 22044433673 scopus 로고    scopus 로고
    • Safety and efficacy of mechanical embolectomy in acute ischemic stroke: Results of the MERCI trial
    • Smith WS, Sung G, Starkman S, et al. 2005. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 36:1432-38
    • (2005) Stroke , vol.36 , pp. 1432-1438
    • Smith, W.S.1    Sung, G.2    Starkman, S.3
  • 34
    • 33745270800 scopus 로고    scopus 로고
    • Stent-assisted intracranial recanalization for acute stroke: Early results
    • Levy EI, Ecker R, Horowitz MB, et al. 2006. Stent-assisted intracranial recanalization for acute stroke: early results. Neurosurgery 58:458-63
    • (2006) Neurosurgery , vol.58 , pp. 458-463
    • Levy, E.I.1    Ecker, R.2    Horowitz, M.B.3
  • 35
    • 0034643745 scopus 로고    scopus 로고
    • Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy: ASPECTS Study Group
    • Barber PA, Demchuk AM, Zhang J, Buchan AM. 2000. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy: ASPECTS Study Group. Lancet 355:1670-74
    • (2000) Lancet , vol.355 , pp. 1670-1674
    • Barber, P.A.1    Demchuk, A.M.2    Zhang, J.3    Buchan, A.M.4
  • 36
    • 33645800351 scopus 로고    scopus 로고
    • Extent of early ischemic changes on computed tomography before thrombolysis: Prognostic value of the Alberta Stroke Program Early CT score in ECASS II
    • Dzialowski I, Hill M, Coutts SB, et al. 2006. Extent of early ischemic changes on computed tomography before thrombolysis: prognostic value of the Alberta Stroke Program Early CT score in ECASS II. Stroke 37:973-78
    • (2006) Stroke , vol.37 , pp. 973-978
    • Dzialowski, I.1    Hill, M.2    Coutts, S.B.3
  • 37
    • 0034753841 scopus 로고    scopus 로고
    • CT angiography in the rapid triage of patients with hyperacute stroke: Accuracy in the detection of large vessel thrombus
    • Lev MH, Farkas J, Rodriguez V, et al. 2001. CT angiography in the rapid triage of patients with hyperacute stroke: accuracy in the detection of large vessel thrombus. J. Compu. Axial Tomogr. 25:520-28
    • (2001) J. Compu. Axial Tomogr , vol.25 , pp. 520-528
    • Lev, M.H.1    Farkas, J.2    Rodriguez, V.3
  • 38
    • 0032902158 scopus 로고    scopus 로고
    • Hyperacute stroke: Simultaneous measurement of relative cerebral blood volume, relative blood flow and mean tissue transit time
    • Sorensen AG, Copen WC, Ostergaard L, et al. 1999. Hyperacute stroke: simultaneous measurement of relative cerebral blood volume, relative blood flow and mean tissue transit time. Radiology 210:519-27
    • (1999) Radiology , vol.210 , pp. 519-527
    • Sorensen, A.G.1    Copen, W.C.2    Ostergaard, L.3
  • 39
    • 8344252685 scopus 로고    scopus 로고
    • Does the acute diffusion-weighted imaging lesion represent penumbra as well as core? A combined quantitative PET/MRI voxel-based study
    • Guadeagno JV, Warburton EA, Aigbirhio FI, et al. 2004. Does the acute diffusion-weighted imaging lesion represent penumbra as well as core? A combined quantitative PET/MRI voxel-based study. J. Cerebr. Blood Flow Metabol. 24:1249-54
    • (2004) J. Cerebr. Blood Flow Metabol , vol.24 , pp. 1249-1254
    • Guadeagno, J.V.1    Warburton, E.A.2    Aigbirhio, F.I.3
  • 40
    • 0034836305 scopus 로고    scopus 로고
    • Frequency and clinical context of decreased apparent diffusion coefficient reversal in the human brain
    • Grant PE, He J, Halpern EF, et al. 2001. Frequency and clinical context of decreased apparent diffusion coefficient reversal in the human brain. Radiology 221:43-50
    • (2001) Radiology , vol.221 , pp. 43-50
    • Grant, P.E.1    He, J.2    Halpern, E.F.3
  • 41
    • 0036315280 scopus 로고    scopus 로고
    • Neuroimaging of acute stroke: A study of 691 emergency department cases
    • Mullins ME, Schaefer PW, Halpern EF, et al. 2002. Neuroimaging of acute stroke: a study of 691 emergency department cases. Radiology 224(2):353-60
    • (2002) Radiology , vol.224 , Issue.2 , pp. 353-360
    • Mullins, M.E.1    Schaefer, P.W.2    Halpern, E.F.3
  • 42
    • 0031729295 scopus 로고    scopus 로고
    • Time course of lesion development in patients with acute stroke: Serial diffusion and hemodynamic-weighted magnetic resonance imaging
    • Schwamm L, Koroshetz WJ, Sorensen AG, et al. 1998. Time course of lesion development in patients with acute stroke: serial diffusion and hemodynamic-weighted magnetic resonance imaging. Stroke 29:2268-76
    • (1998) Stroke , vol.29 , pp. 2268-2276
    • Schwamm, L.1    Koroshetz, W.J.2    Sorensen, A.G.3
  • 43
    • 0031981370 scopus 로고    scopus 로고
    • Regional ischemia and ischemic injury in patients with acute middle cerebral artery stroke as defined by early diffusion-weighted and perfusion-weighted MRI
    • Rordorf G, Koroshetz WJ, Copen WA, et al. 1998. Regional ischemia and ischemic injury in patients with acute middle cerebral artery stroke as defined by early diffusion-weighted and perfusion-weighted MRI. Stroke 29:939-43
    • (1998) Stroke , vol.29 , pp. 939-943
    • Rordorf, G.1    Koroshetz, W.J.2    Copen, W.A.3
  • 44
    • 18244367363 scopus 로고    scopus 로고
    • Does the mismatch match the penumbra? Magnetic resonance imaging and positron emission tomography in early ischemic stroke
    • Sobesky J, Wever OZ, Lehnhardt FG, et al. 2005. Does the mismatch match the penumbra? Magnetic resonance imaging and positron emission tomography in early ischemic stroke. Stroke 36:980-85
    • (2005) Stroke , vol.36 , pp. 980-985
    • Sobesky, J.1    Wever, O.Z.2    Lehnhardt, F.G.3
  • 45
    • 0036972193 scopus 로고    scopus 로고
    • Footprints of transient ischemic attacks: A diffusion-weighted MRI study
    • Ay H, Schaefer PM, Furie KL, et al. 2002. "Footprints" of transient ischemic attacks: a diffusion-weighted MRI study. Cerebrovasc. Dis. 14:177-86
    • (2002) Cerebrovasc. Dis , vol.14 , pp. 177-186
    • Ay, H.1    Schaefer, P.M.2    Furie, K.L.3
  • 46
    • 0034108310 scopus 로고    scopus 로고
    • Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling
    • Chalela JA, Alsop DC, Gonzalez-Atavales JB, et al. 2000. Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling. Stroke 31:680-87
    • (2000) Stroke , vol.31 , pp. 680-687
    • Chalela, J.A.1    Alsop, D.C.2    Gonzalez-Atavales, J.B.3
  • 47
    • 0034820214 scopus 로고    scopus 로고
    • Utility of perfusion weighted CT imaging in acute MCA stroke treated with intra-arterial thrombolysis: Prediction of final infarct volume and clinical outcome
    • Lev MH, Segal AZ, Farkas J, et al. 2001. Utility of perfusion weighted CT imaging in acute MCA stroke treated with intra-arterial thrombolysis: prediction of final infarct volume and clinical outcome. Stroke 32:2021-28
    • (2001) Stroke , vol.32 , pp. 2021-2028
    • Lev, M.H.1    Segal, A.Z.2    Farkas, J.3
  • 48
    • 33645817175 scopus 로고    scopus 로고
    • Perfusion-CT assessment of infarct core and penumbra: Receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke
    • Wintermark M, Flanders AE, Velthuis B, et al. 2006. Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke. Stroke 37:979-85
    • (2006) Stroke , vol.37 , pp. 979-985
    • Wintermark, M.1    Flanders, A.E.2    Velthuis, B.3
  • 49
    • 19944426190 scopus 로고    scopus 로고
    • The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): A phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase
    • Hacke W, Albers G, Al-Rawi Y, et al. 2005. The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke 36:66-73
    • (2005) Stroke , vol.36 , pp. 66-73
    • Hacke, W.1    Albers, G.2    Al-Rawi, Y.3
  • 50
    • 34248212567 scopus 로고    scopus 로고
    • Results of the DEFUSE trial
    • Presented at, Kissimmee, FL
    • Albers G. 2006. Results of the DEFUSE trial. Presented at Int. Stroke Conf., Kissimmee, FL
    • (2006) Int. Stroke Conf
    • Albers, G.1
  • 51
    • 32144453826 scopus 로고    scopus 로고
    • Lees KR, Zivin JA, Ashwood T, et al., Stroke-Acute Ischemic NXY Treatment (SAINT I) Trial Investigators. 2006. NXY-059 for acute ischemic stroke. N. Engl. J. Med. 354(6):588-600
    • Lees KR, Zivin JA, Ashwood T, et al., Stroke-Acute Ischemic NXY Treatment (SAINT I) Trial Investigators. 2006. NXY-059 for acute ischemic stroke. N. Engl. J. Med. 354(6):588-600
  • 52
    • 2342535001 scopus 로고    scopus 로고
    • Saver JL, Kidwell C, Eckstein M, Starkman S, FAST-MAG Pilot Trial Investigators. 2004. Prehospital neuroprotective therapy for acute stroke: results of the Field Administration of Stroke Therapy-Magnesium (FAST-MAG) pilot trial. Stroke 35(5):e106-108
    • Saver JL, Kidwell C, Eckstein M, Starkman S, FAST-MAG Pilot Trial Investigators. 2004. Prehospital neuroprotective therapy for acute stroke: results of the Field Administration of Stroke Therapy-Magnesium (FAST-MAG) pilot trial. Stroke 35(5):e106-108
  • 53
    • 16844384023 scopus 로고    scopus 로고
    • A pilot study of normobaric oxygen therapy in acute ischemic stroke
    • Singhal AB, Benner T, Roccatagliata L, et al. 2005. A pilot study of normobaric oxygen therapy in acute ischemic stroke. Stroke 36:797-802
    • (2005) Stroke , vol.36 , pp. 797-802
    • Singhal, A.B.1    Benner, T.2    Roccatagliata, L.3
  • 54
    • 85136387354 scopus 로고    scopus 로고
    • Publication Committee for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators. 1998. Low molecular weight heparinoid, ORG 10172 danaparoid, and outcome after acute ischemic stroke: a randomized controlled trial. JAMA 2729:1265-72
    • Publication Committee for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators. 1998. Low molecular weight heparinoid, ORG 10172 danaparoid, and outcome after acute ischemic stroke: a randomized controlled trial. JAMA 2729:1265-72
  • 55
    • 0030911057 scopus 로고    scopus 로고
    • The International Stroke Trial (IST): A randomized trial of aspirin, subcutaneous heparin, both, or neither among 19,435 patients with acute ischemic stroke
    • International Stroke Trial Collaborative Group
    • International Stroke Trial Collaborative Group. 1997. The International Stroke Trial (IST): a randomized trial of aspirin, subcutaneous heparin, both, or neither among 19,435 patients with acute ischemic stroke. Lancet 349:1569-81
    • (1997) Lancet , vol.349 , pp. 1569-1581
  • 56
    • 0028871958 scopus 로고
    • Low-molecular-weight heparin for the treatment of acute ischemic stroke
    • Kay R, Wong KS, Yu YL, et al. 1995. Low-molecular-weight heparin for the treatment of acute ischemic stroke. N. Engl. J. Med. 333:1588-93
    • (1995) N. Engl. J. Med , vol.333 , pp. 1588-1593
    • Kay, R.1    Wong, K.S.2    Yu, Y.L.3
  • 57
    • 34248229534 scopus 로고    scopus 로고
    • Results of the Fraxiparin in Stroke Study
    • Presented at, Kissimmee, FL
    • Wong KSL. 2006. Results of the Fraxiparin in Stroke Study. Presented at Int. Stroke Conf., Kissimmee, FL
    • (2006) Int. Stroke Conf
    • Wong, K.S.L.1
  • 58
    • 0034621003 scopus 로고    scopus 로고
    • Low molecular weight heparin versus aspirin in patients with acute ischemic stroke and atrial fibrillation: A double blind randomised study. HAEST Study Group. Heparin in Acute Embolic Stroke Trial
    • Berge E, Abdelnoor M, Nakstad PH, Sandset PM. 2000. Low molecular weight heparin versus aspirin in patients with acute ischemic stroke and atrial fibrillation: a double blind randomised study. HAEST Study Group. Heparin in Acute Embolic Stroke Trial. Lancet 355:1205-10
    • (2000) Lancet , vol.355 , pp. 1205-1210
    • Berge, E.1    Abdelnoor, M.2    Nakstad, P.H.3    Sandset, P.M.4
  • 59
    • 27644546336 scopus 로고    scopus 로고
    • Intravenous heparin started within the first 3 hours after onset of symptoms as a treatment for acute nonlacunar hemispheric cerebral infarctions
    • Camerlingo M, Salvi P, Belloni G, et al. 2005. Intravenous heparin started within the first 3 hours after onset of symptoms as a treatment for acute nonlacunar hemispheric cerebral infarctions. Stroke 36:2415-20
    • (2005) Stroke , vol.36 , pp. 2415-2420
    • Camerlingo, M.1    Salvi, P.2    Belloni, G.3
  • 60
    • 0030985284 scopus 로고    scopus 로고
    • CAST: Randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischemic stroke
    • CAST (Chinese Acute Stroke Trial) Collaborative Group
    • CAST (Chinese Acute Stroke Trial) Collaborative Group. 1997. CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischemic stroke. Lancet 349(9066):1641-49
    • (1997) Lancet , vol.349 , Issue.9066 , pp. 1641-1649
  • 61
    • 24944466539 scopus 로고    scopus 로고
    • Neurotransplantation for patients with subcortical motor stroke: A phase 2 randomized trial
    • Kondziolka D, Steinberg GK, Wechsler L, et al. 2005. Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial. J. Neurosur. 103(1):38-34
    • (2005) J. Neurosur , vol.103 , Issue.1 , pp. 38-34
    • Kondziolka, D.1    Steinberg, G.K.2    Wechsler, L.3
  • 62
    • 33645567790 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor for acute ischemic stroke: A randomized controlled trial
    • Shyu WC, Lin SZ, Lee CC, et al. 2006. Granulocyte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial. Can. Med. Assoc. J. 174:927-33
    • (2006) Can. Med. Assoc. J , vol.174 , pp. 927-933
    • Shyu, W.C.1    Lin, S.Z.2    Lee, C.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.