C-1027, a radiomimetic enediyne anticancer drug, preferentially targets hypoxic cells

Cancer Research

Volumn 69, Issue 2, 2009, Pages 593-598

  Beerman, Terry A ^a   Gawron, Loretta S ^a   Shin, Seulkih ^a   Shen, Ben ^b   McHugh, Mary M ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC C 1027; ENEDIYNE; ZINOSTATIN;

ARTICLE; CELL FREE SYSTEM; CELL HYPOXIA; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DNA CROSS LINKING; DNA STRAND BREAKAGE; DRUG STRUCTURE; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; RADIOSENSITIVITY; TARGET CELL;

AMINOGLYCOSIDES; ANTIBIOTICS, ANTINEOPLASTIC; CELL HYPOXIA; COLONIC NEOPLASMS; DNA DAMAGE; DNA, SUPERHELICAL; ENEDIYNES; HCT116 CELLS; HISTONES; HUMANS; OXYGEN; PLASMIDS; SIGNAL TRANSDUCTION;

EID: 58349094536     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-2753     Document Type: Article

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