메뉴 건너뛰기




Volumn 74, Issue SUPPL. XXVII, 1996, Pages

The molecular response of mammalian cells to hypoxia and the potential for exploitation in cancer therapy

Author keywords

Erythropoietin; Gene therapy; Hypoxia; Hypoxia inducible factor 1; Vascular endothelial growth factor

Indexed keywords

CYTOKINE; ERYTHROPOIETIN; GROWTH FACTOR; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TRANSCRIPTION FACTOR; VASCULOTROPIN; DNA BINDING PROTEIN; ENDOTHELIAL CELL GROWTH FACTOR; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LYMPHOKINE; NUCLEAR PROTEIN; VASCULOTROPIN A;

EID: 0029976685     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (71)

References (82)
  • 3
    • 0027172514 scopus 로고
    • Characterisation of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-kD nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells
    • BECK I, WEINMANN R AND CARO J. (1993). Characterisation of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-kD nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells. Blood, 82, 704-711.
    • (1993) Blood , vol.82 , pp. 704-711
    • Beck, I.1    Weinmann, R.2    Caro, J.3
  • 4
    • 0024999067 scopus 로고
    • Activation of the heat shock transcription factor by hypoxia in mammalian cells
    • BENJAMIN IJ, KROEGER B AND WILLIAMS RS. (1990). Activation of the heat shock transcription factor by hypoxia in mammalian cells. Proc. Natl Acad. Sci. USA, 87, 6263-6267.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 6263-6267
    • Benjamin, I.J.1    Kroeger, B.2    Williams, R.S.3
  • 5
    • 0025797414 scopus 로고
    • Novel growth regulatory factors and tumour angiogenesis
    • BICKNELL R AND HARRIS AL. (1991). Novel growth regulatory factors and tumour angiogenesis. Eur. J. Cancer, 27, 785-789.
    • (1991) Eur. J. Cancer , vol.27 , pp. 785-789
    • Bicknell, R.1    Harris, A.L.2
  • 6
    • 0028032964 scopus 로고
    • The effects of reduced perfusion and reperfusion on c-fos and HSP-72 protein immunohistochemistry in gestational day 21 rat brains
    • BINIENDA Z AND SCALLET AC. (1994). The effects of reduced perfusion and reperfusion on c-fos and HSP-72 protein immunohistochemistry in gestational day 21 rat brains. Int. J. Dev. Neuroscience, 12, 605-610.
    • (1994) Int. J. Dev. Neuroscience , vol.12 , pp. 605-610
    • Binienda, Z.1    Scallet, A.C.2
  • 10
    • 0027970536 scopus 로고
    • Role of hydrogen peroxide in hypoxia induced erythropoietin production
    • FANDREY J, FREDE S AND JELKMANN W. (1994). Role of hydrogen peroxide in hypoxia induced erythropoietin production. Biochem. J., 303, 507-510.
    • (1994) Biochem. J. , vol.303 , pp. 507-510
    • Fandrey, J.1    Frede, S.2    Jelkmann, W.3
  • 11
    • 0028897916 scopus 로고
    • Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor. Biochem
    • FINKENZELLER G, TECHNAU A AND MARME D. (1995). Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor. Biochem. Biophys. Res. Commun., 208, 432-439.
    • (1995) Biophys. Res. Commun. , vol.208 , pp. 432-439
    • Finkenzeller, G.1    Technau, A.2    Marme, D.3
  • 12
    • 0028359320 scopus 로고
    • Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with erythropoietin 3′ enhancer
    • FIRTH JD, EBERT BL, PUGH CW AND RATCLIFFE PJ. (1994). Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with erythropoietin 3′ enhancer. Proc. Natl Acad. Sci. USA, 91, 6496-6500.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 6496-6500
    • Firth, J.D.1    Ebert, B.L.2    Pugh, C.W.3    Ratcliffe, P.J.4
  • 13
    • 0028967752 scopus 로고
    • The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonised by EAR3/COUP-TF1
    • GALSON DL, TSUCHIYA T, TENDLER DS, HUANG LE, REN Y, OGURA T AND BUNN HF. (1995). The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonised by EAR3/COUP-TF1. Mol. Cell. Biol., 15, 2135-2144.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2135-2144
    • Galson, D.L.1    Tsuchiya, T.2    Tendler, D.S.3    Huang, L.E.4    Ren, Y.5    Ogura, T.6    Bunn, H.F.7
  • 15
    • 0028843411 scopus 로고
    • Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents
    • GLEADLE JM, EBERT BL, FIRTH JD AND RATCLIFFE PJ. (1995). Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents. Am. J. Physiol., 37, C1362-C1368.
    • (1995) Am. J. Physiol. , vol.37
    • Gleadle, J.M.1    Ebert, B.L.2    Firth, J.D.3    Ratcliffe, P.J.4
  • 16
    • 0028095127 scopus 로고
    • Similarities between the oxygen-sensing mechanism regulating the expression of vascular endothelial growth factor and erythropoietin
    • GOLDBERG MA AND SCHNEIDER TJ. (1994). Similarities between the oxygen-sensing mechanism regulating the expression of vascular endothelial growth factor and erythropoietin. J. Biol. Chem., 269, 4355-4359.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4355-4359
    • Goldberg, M.A.1    Schneider, T.J.2
  • 17
    • 0024273450 scopus 로고
    • Regulation of the erythropoietin gene: Evidence that the oxygen sensor is a heme protein
    • GOLDBERG MA, DUNNING SP AND BUNN HF. (1988). Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. Science, 242, 1412-1415.
    • (1988) Science , vol.242 , pp. 1412-1415
    • Goldberg, M.A.1    Dunning, S.P.2    Bunn, H.F.3
  • 19
    • 0025972125 scopus 로고
    • Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events
    • GOLDBERG MA, GAUT CC AND BUNN HF. (1991). Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events. Blood, 77, 271.
    • (1991) Blood , vol.77 , pp. 271
    • Goldberg, M.A.1    Gaut, C.C.2    Bunn, H.F.3
  • 20
    • 0028110809 scopus 로고
    • Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low oxygen conditions is independent of p53 status
    • GRAEBER TG, PETERSON JF, TSAI M, MONICA K, FORNACE AJ AND GIACCIA AJ. (1994). Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low oxygen conditions is independent of p53 status. Mol. Cell. Biol., 14, 6264-6277.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6264-6277
    • Graeber, T.G.1    Peterson, J.F.2    Tsai, M.3    Monica, K.4    Fornace, A.J.5    Giaccia, A.J.6
  • 21
    • 0027971167 scopus 로고
    • Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia
    • GRAVEN KK, TROXLER RF, KORNFELD H, PANCHENKO MV AND FARBER HW. (1994). Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia. J. Biol. Chem., 269, 24446-24453.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24446-24453
    • Graven, K.K.1    Troxler, R.F.2    Kornfeld, H.3    Panchenko, M.V.4    Farber, H.W.5
  • 22
    • 0026639837 scopus 로고
    • Bioactivation of mitomycin C by xanthine dehydrogenase from EMT6 mouse mammary carcinoma tumours
    • GUSTAFSON DL AND PRITSOS CA. (1992). Bioactivation of mitomycin C by xanthine dehydrogenase from EMT6 mouse mammary carcinoma tumours. J. Natl Cancer Inst., 84, 1180-1185.
    • (1992) J. Natl Cancer Inst. , vol.84 , pp. 1180-1185
    • Gustafson, D.L.1    Pritsos, C.A.2
  • 24
    • 0028918766 scopus 로고
    • Characterization of the promoter region of the human apurinic endonuclease gene (APE)
    • HARRISON L, ASCIONE AG, WILSON DM AND DEMPLE B. (1995). Characterization of the promoter region of the human apurinic endonuclease gene (APE). J. Biol. Chem., 270, 5556-5564.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5556-5564
    • Harrison, L.1    Ascione, A.G.2    Wilson, D.M.3    Demple, B.4
  • 25
    • 0025776467 scopus 로고
    • Effects of hypoxia and reoxygenation on the conversion of xanthine dehydrogenase to oxidase in chinese hamster V79 cells
    • HASAN NM, CUNDALL RB AND ADAMS GE. (1991). Effects of hypoxia and reoxygenation on the conversion of xanthine dehydrogenase to oxidase in chinese hamster V79 cells. Free Rad. Biol. Med., 11, 179-185.
    • (1991) Free Rad. Biol. Med. , vol.11 , pp. 179-185
    • Hasan, N.M.1    Cundall, R.B.2    Adams, G.E.3
  • 28
    • 0028352735 scopus 로고
    • Age and development related changes in osteopontin and nitric oxide synthase messenger RNA levels in human kidney proximal tubule epithelial cells - Contrasting responses to hypoxia and reoxygenation
    • HWANG SM, WILSON PD, LASKIN JD AND DENHARDT DT. (1994). Age and development related changes in osteopontin and nitric oxide synthase messenger RNA levels in human kidney proximal tubule epithelial cells - contrasting responses to hypoxia and reoxygenation. J. Cell. Physiol., 160, 61-68.
    • (1994) J. Cell. Physiol. , vol.160 , pp. 61-68
    • Hwang, S.M.1    Wilson, P.D.2    Laskin, J.D.3    Denhardt, D.T.4
  • 30
    • 0025271438 scopus 로고
    • Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365nm) radiation: Evidence for the involvement of the hydroxy radical
    • KEYSE SM AND TYRRELL RM. (1990). Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365nm) radiation: Evidence for the involvement of the hydroxy radical. Carcinogenesis, 11, 787-791.
    • (1990) Carcinogenesis , vol.11 , pp. 787-791
    • Keyse, S.M.1    Tyrrell, R.M.2
  • 31
    • 0026437792 scopus 로고
    • Brain nitric oxide is a haemoprotein
    • KLATT P, SCHMIDT K AND MAYER B. (1992). Brain nitric oxide is a haemoprotein. Biochem. J., 288, 15-17.
    • (1992) Biochem. J. , vol.288 , pp. 15-17
    • Klatt, P.1    Schmidt, K.2    Mayer, B.3
  • 33
    • 0028268629 scopus 로고
    • Hypoxia causes the activation of nuclear factor κB through phosphorylation of IκBα on tyrosine residues
    • KOONG AC, CHEN EY AND GIACCIA AJ. (1994). Hypoxia causes the activation of nuclear factor κB through phosphorylation of IκBα on tyrosine residues. Cancer Res., 54, 1425-1430.
    • (1994) Cancer Res. , vol.54 , pp. 1425-1430
    • Koong, A.C.1    Chen, E.Y.2    Giaccia, A.J.3
  • 35
    • 0026758210 scopus 로고
    • Enhanced epidermal growth factor receptor synthesis in human squamous carcinoma cells exposed to low levels of oxygen
    • LADEROUTE KR, GRANT TD, MURPHY BJ AND SUTHERLAND RM. (1992a). Enhanced epidermal growth factor receptor synthesis in human squamous carcinoma cells exposed to low levels of oxygen. Int. J. Cancer, 52, 428-432.
    • (1992) Int. J. Cancer , vol.52 , pp. 428-432
    • Laderoute, K.R.1    Grant, T.D.2    Murphy, B.J.3    Sutherland, R.M.4
  • 36
    • 0026530685 scopus 로고
    • Enhancement of transforming growth factor-α synthesis in multicellular tumour spheroids of A431 squamous carcinoma cells
    • LADEROUTE KR, MURPHY BJ, SHORT SM, GRANT TD, KNAPP AM AND SUTHERLAND RM. (1992b). Enhancement of transforming growth factor-α synthesis in multicellular tumour spheroids of A431 squamous carcinoma cells. Br. J. Cancer, 65, 157-162.
    • (1992) Br. J. Cancer , vol.65 , pp. 157-162
    • Laderoute, K.R.1    Murphy, B.J.2    Short, S.M.3    Grant, T.D.4    Knapp, A.M.5    Sutherland, R.M.6
  • 37
    • 0027328476 scopus 로고
    • Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart
    • LADOUX A AND FRELIN C. (1993). Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart, Biochem. Biophys. Res. Commun., 195, 1005-1010.
    • (1993) Biochem. Biophys. Res. Commun. , vol.195 , pp. 1005-1010
    • Ladoux, A.1    Frelin, C.2
  • 38
    • 0028307310 scopus 로고
    • Identification of binding sites for the transcription factor NF-κB and AP-2 in the promoter region of the human heme oxygenase 1 gene
    • LAVROVSKY Y, SCHWARTZBAUM ML, LEVERE RD, KAPPAS A AND ABRAHAM NG. (1994). Identification of binding sites for the transcription factor NF-κB and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc. Natl Acad. Sci. USA, 91, 5987-5991.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 5987-5991
    • Lavrovsky, Y.1    Schwartzbaum, M.L.2    Levere, R.D.3    Kappas, A.4    Abraham, N.G.5
  • 39
    • 0027878080 scopus 로고
    • The 3′ flanking region of the human erythropoietin-encoding gene contains nitrogen-regulatory oxygen-sensing consensus sequences and tissue-specific transcriptional regulatory elements
    • LEEHUANG S, LIN JJ, KUNG HF, HUANG PL, LEE L AND HUANG PL. (1993). The 3′ flanking region of the human erythropoietin-encoding gene contains nitrogen-regulatory oxygen-sensing consensus sequences and tissue-specific transcriptional regulatory elements. Gene, 137, 203-210.
    • (1993) Gene , vol.137 , pp. 203-210
    • Leehuang, S.1    Lin, J.J.2    Kung, H.F.3    Huang, P.L.4    Lee, L.5    Huang, P.L.6
  • 40
    • 0028924795 scopus 로고
    • Deferral prevents against cell lysis induced by hydrogen peroxide to hypoxic hepatocytes: A role for free iron in hypoxia-mediated cellular injury
    • LEFEBVRE V AND BUCCALDERON P. (1995). Deferral prevents against cell lysis induced by hydrogen peroxide to hypoxic hepatocytes: A role for free iron in hypoxia-mediated cellular injury. Chem. Biol. Int., 94, 37-48.
    • (1995) Chem. Biol. Int. , vol.94 , pp. 37-48
    • Lefebvre, V.1    Buccalderon, P.2
  • 41
    • 0027230099 scopus 로고
    • A 24-base-pair sequence 3′ to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer
    • MADAN A AND CURTIN PT. (1993). A 24-base-pair sequence 3′ to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer. Proc. Natl Acad. Sci. USA, 90, 3928-3932.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 3928-3932
    • Madan, A.1    Curtin, P.T.2
  • 42
    • 0029002253 scopus 로고
    • Regulated basal, inducible, and tissue-specific human erythropoietin gene expression in transgenic mice requires multiple cis DNA sequences
    • MADAN A, LIN C, HATCH SL AND CURTIN PT. (1995). Regulated basal, inducible, and tissue-specific human erythropoietin gene expression in transgenic mice requires multiple cis DNA sequences. Blood, 85, 2735-2741.
    • (1995) Blood , vol.85 , pp. 2735-2741
    • Madan, A.1    Lin, C.2    Hatch, S.L.3    Curtin, P.T.4
  • 43
    • 0028105848 scopus 로고
    • Hypoxia regulatory elements of the human vascular endothelial growth factor gene
    • MINCHENKO A, SALCEDA S, BAUER T AND CARO J. (1994). Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cell. Mol. Biol. Res., 40, 35-39.
    • (1994) Cell. Mol. Biol. Res. , vol.40 , pp. 35-39
    • Minchenko, A.1    Salceda, S.2    Bauer, T.3    Caro, J.4
  • 44
    • 0029068339 scopus 로고
    • Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
    • MUKHOPADHYAY D, TSIOKAS L, ZHOU ZM, FOSTER D, BRUGGE JS AND SUKHATME VP. (1995). Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature, 375, 577-581.
    • (1995) Nature , vol.375 , pp. 577-581
    • Mukhopadhyay, D.1    Tsiokas, L.2    Zhou, Z.M.3    Foster, D.4    Brugge, J.S.5    Sukhatme, V.P.6
  • 45
    • 0025868208 scopus 로고
    • The identification of heme oxygenase as a major hypoxic stress protein in chinese hamster ovary cells
    • MURPHY BJ, LADEROUTE KR, SHORT SM AND SUTHERLAND RM. (1991). The identification of heme oxygenase as a major hypoxic stress protein in chinese hamster ovary cells. Br. J. Cancer, 64, 69-73.
    • (1991) Br. J. Cancer , vol.64 , pp. 69-73
    • Murphy, B.J.1    Laderoute, K.R.2    Short, S.M.3    Sutherland, R.M.4
  • 46
    • 0027312723 scopus 로고
    • Interaction of nitric oxide and cyclic guanosine 3′,5′-monophosphate in erythropoietin production
    • OHIGASHI T, BROOKINS J AND FISHER JW. (1993). Interaction of nitric oxide and cyclic guanosine 3′,5′-monophosphate in erythropoietin production. J. Clin. Invest., 92, 1587-1591.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1587-1591
    • Ohigashi, T.1    Brookins, J.2    Fisher, J.W.3
  • 48
    • 0028032714 scopus 로고
    • Extracellular iron chelators protect kidney cells from hypoxia, reoxygenation
    • PALLER MS AND HEDLUND BE. (1994). Extracellular iron chelators protect kidney cells from hypoxia, reoxygenation. Free Rad. Biol. Med., 17, 597-603.
    • (1994) Free Rad. Biol. Med. , vol.17 , pp. 597-603
    • Paller, M.S.1    Hedlund, B.E.2
  • 49
    • 0028867912 scopus 로고
    • Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR4233)
    • PATTERSON AV, BARHAM HM, CHINJE EC, ADAMS GE, HARRIS AL AND STRATFORD IJ. (1995). Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR4233). Br. J. Cancer, 72, 1144-1150.
    • (1995) Br. J. Cancer , vol.72 , pp. 1144-1150
    • Patterson, A.V.1    Barham, H.M.2    Chinje, E.C.3    Adams, G.E.4    Harris, A.L.5    Stratford, I.J.6
  • 51
    • 0027209915 scopus 로고
    • A cooperative interaction between NF-κB and Spl is required for HIV-1 enhancer activation
    • PERKINS ND, EDWARDS NL, DUCKET CS, AGRANOFF AB, SCHMID RM AND NABEL GJ. (1993). A cooperative interaction between NF-κB and Spl is required for HIV-1 enhancer activation. EMBO J., 12, 3551-3558.
    • (1993) EMBO J. , vol.12 , pp. 3551-3558
    • Perkins, N.D.1    Edwards, N.L.2    Ducket, C.S.3    Agranoff, A.B.4    Schmid, R.M.5    Nabel, G.J.6
  • 52
    • 0026439870 scopus 로고
    • Platelet-derived growth factor receptor-β is induced during tumour development and upregulated during tumour progression in endothelial cells in human gliomas
    • PLATE KH, BREIER G, FARRELL C AND RISAU W. (1992a). Platelet-derived growth factor receptor-β is induced during tumour development and upregulated during tumour progression in endothelial cells in human gliomas. Lab. Invest., 67, 529-534.
    • (1992) Lab. Invest. , vol.67 , pp. 529-534
    • Plate, K.H.1    Breier, G.2    Farrell, C.3    Risau, W.4
  • 53
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • PLATE KH, BREIER G, WEICH HA AND RISAU W. (1992b). Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature, 359, 845-848.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 54
    • 0027432324 scopus 로고
    • Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis
    • PLATE KH, BREIER G, MILLAUER B, ULLRICH A AND RISAU W. (1993). Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis. Cancer Res., 53, 5822-5827.
    • (1993) Cancer Res. , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 55
    • 0024307838 scopus 로고
    • Hypoxia stimulates release of endothelium-derived relaxant factor
    • POHL U AND BUSSE R. (1989). Hypoxia stimulates release of endothelium-derived relaxant factor. Am. J. Physiol. (Heart Circ. Physiol.), 256, H1595-H1600.
    • (1989) Am. J. Physiol. (Heart Circ. Physiol.) , vol.256
    • Pohl, U.1    Busse, R.2
  • 56
    • 0026613094 scopus 로고
    • Heat induced transcription from RNA polymerases II and III and HSF binding are coordinately regulated by the products of the heat shock genes
    • PRICE BD AND CALDERWOOD SK. (1993). Heat induced transcription from RNA polymerases II and III and HSF binding are coordinately regulated by the products of the heat shock genes. J. Cell Physiol., 153, 392-401.
    • (1993) J. Cell Physiol. , vol.153 , pp. 392-401
    • Price, B.D.1    Calderwood, S.K.2
  • 57
    • 0028279870 scopus 로고
    • Characterisation of functional domains within the mouse erythropoietin 3′ enhancer conveying oxygen-regulated responses in different cell-lines
    • PUGH CW, EBERT BL, EBRAHIM O AND RATCLIFFE PJ. (1994a). Characterisation of functional domains within the mouse erythropoietin 3′ enhancer conveying oxygen-regulated responses in different cell-lines. Biochim. Biophys. Acta 1217, 297-306.
    • (1994) Biochim. Biophys. Acta , vol.1217 , pp. 297-306
    • Pugh, C.W.1    Ebert, B.L.2    Ebrahim, O.3    Ratcliffe, P.J.4
  • 58
    • 0028235188 scopus 로고
    • Analysis of cis-acting sequences required for operation of the erythropoietin 3′ enhancer in different cell lines
    • PUGH CW, EBERT BL, EBRAHIM O, MAXWELL PH AND RATCLIFFE PJ. (1994b). Analysis of cis-acting sequences required for operation of the erythropoietin 3′ enhancer in different cell lines. Ann. NY Acad. Sci., 718, 31-39.
    • (1994) Ann. NY Acad. Sci. , vol.718 , pp. 31-39
    • Pugh, C.W.1    Ebert, B.L.2    Ebrahim, O.3    Maxwell, P.H.4    Ratcliffe, P.J.5
  • 59
    • 0029029016 scopus 로고
    • Hypoxia alters iron homeostasis and induces ferritin synthesis in oligodendrocytes
    • QI Y, JAMINDAR TM AND DAWSON G. (1995). Hypoxia alters iron homeostasis and induces ferritin synthesis in oligodendrocytes. J. Neurochem., 64, 2458-2464.
    • (1995) J. Neurochem. , vol.64 , pp. 2458-2464
    • Qi, Y.1    Jamindar, T.M.2    Dawson, G.3
  • 60
    • 0028101349 scopus 로고
    • Factors affecting sensitivity to EO9 in rodent and human tumour cells in vitro: DT-diaphorase activity and hypoxia
    • ROBERTSON N, HAIGH A, ADAMS GE AND STRATFORD IJ. (1994). Factors affecting sensitivity to EO9 in rodent and human tumour cells in vitro: DT-diaphorase activity and hypoxia. Eur. J. Cancer, 30A, 1013-1019.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 1013-1019
    • Robertson, N.1    Haigh, A.2    Adams, G.E.3    Stratford, I.J.4
  • 61
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor I
    • SEMENZA GL, ROTH PH, FANG H. AND WANG GL. (1994). Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor I. J. Biol. Chem., 269, 23757-23763.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.3    Wang, G.L.4
  • 62
    • 0023665016 scopus 로고
    • Transcriptional control of rat heme oxygenase by heat shock
    • SHIBAHARA S, MULLER RM AND TAGUCHI H. (1987). Transcriptional control of rat heme oxygenase by heat shock. J. Biol. Chem., 262, 12889-12892.
    • (1987) J. Biol. Chem. , vol.262 , pp. 12889-12892
    • Shibahara, S.1    Muller, R.M.2    Taguchi, H.3
  • 63
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • SHWEIKI D, ITIN A, SOFFER D AND KESHET E. (1992). Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature, 359, 843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 64
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and glucose deficiency in multicellular spheroids: Implications for tumour angiogenesis
    • SHWEIKI D, NEEMAN M, ITIN A AND KESHET E. (1995). Induction of vascular endothelial growth factor expression by hypoxia and glucose deficiency in multicellular spheroids: Implications for tumour angiogenesis. Proc. Natl Acad. Sci. USA, 92, 768-772.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3    Keshet, E.4
  • 65
    • 0029072011 scopus 로고
    • Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells - Synergistic interaction with hypoxia
    • STAVRI GT, ZACHARY IC, BASKERVILLE PA, MARTIN JF AND ERUSALIMSKY JD. (1995). Basic fibroblast growth factor upregulates the expression of vascular endothelial growth factor in vascular smooth muscle cells - Synergistic interaction with hypoxia. Circulation, 92, 11-14.
    • (1995) Circulation , vol.92 , pp. 11-14
    • Stavri, G.T.1    Zachary, I.C.2    Baskerville, P.A.3    Martin, J.F.4    Erusalimsky, J.D.5
  • 66
    • 0026787669 scopus 로고
    • Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells
    • STOLER DL, ANDERSON GR, RUSSO CA, SPINA AM AND BEERMAN TA. (1992). Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells. Cancer Res., 52, 4372-4378.
    • (1992) Cancer Res. , vol.52 , pp. 4372-4378
    • Stoler, D.L.1    Anderson, G.R.2    Russo, C.A.3    Spina, A.M.4    Beerman, T.A.5
  • 67
    • 0023937515 scopus 로고
    • Oxygen concentration regulates the proliferative response of human fibroblasts to serum and growth factor
    • STORCH TG AND TALLEY GD. (1988). Oxygen concentration regulates the proliferative response of human fibroblasts to serum and growth factor. Exp. Cell Res., 175, 317-325.
    • (1988) Exp. Cell Res. , vol.175 , pp. 317-325
    • Storch, T.G.1    Talley, G.D.2
  • 68
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • TISCHER E, MITCHELL R, HARTMAN T, SILVA M, GOSPODAROWICZ D, FIDDES JC AND ABRAHAM JA. (1991). The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J. Biol. Chem., 266, 11947-11954.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11947-11954
    • Tischer, E.1    Mitchell, R.2    Hartman, T.3    Silva, M.4    Gospodarowicz, D.5    Fiddes, J.C.6    Abraham, J.A.7
  • 69
    • 0028940664 scopus 로고
    • Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia
    • TUDOR RM, FLOOR BE AND VOELKEL NF. (1995). Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. J. Clin. Invest., 95, 1798-1807.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1798-1807
    • Tudor, R.M.1    Floor, B.E.2    Voelkel, N.F.3
  • 70
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • ULLRICH A AND SCHLESSINGER J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell, 61, 203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 71
    • 0002972851 scopus 로고
    • Oxygenation of solid tumours
    • Teicher BA, (ed.) Marcel Dekker: New York
    • VAUPEL PW. (1993). Oxygenation of solid tumours. In: Drug Resistance in Oncology, Teicher BA, (ed.) pp. 53-85. Marcel Dekker: New York.
    • (1993) Drug Resistance in Oncology , pp. 53-85
    • Vaupel, P.W.1
  • 72
    • 0028596574 scopus 로고
    • A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress
    • WALKER LJ, CRAIG RB, HARRIS AL AND HICKSON ID. (1994). A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress. Nucleic Acids Res., 22, 4884-4889.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4884-4889
    • Walker, L.J.1    Craig, R.B.2    Harris, A.L.3    Hickson, I.D.4
  • 73
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene-expression and hypoxia-inducible factor-1 DNA-binding activity - Implications for models of hypoxia signal-transduction
    • WANG GL AND SEMENZA GL. (1993a). Desferrioxamine induces erythropoietin gene-expression and hypoxia-inducible factor-1 DNA-binding activity - Implications for models of hypoxia signal-transduction. Blood, 82, 3610-3615.
    • (1993) Blood , vol.82 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 74
    • 0027210562 scopus 로고
    • General involvement of hypoxia-inducible factor-1 in transcriptional response to hypoxia
    • WANG GL AND SEMENZA GL. (1993b). General involvement of hypoxia-inducible factor-1 in transcriptional response to hypoxia. Proc. Natl Acad. Sci. USA, 90, 4304-4308.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 4304-4308
    • Wang, G.L.1    Semenza, G.L.2
  • 75
    • 0027427588 scopus 로고
    • Characterization of hypoxia-inducible factor-1 and regulation of DNA-binding activity by hypoxia
    • WANG GL AND SEMENZA GL. (1993c). Characterization of hypoxia-inducible factor-1 and regulation of DNA-binding activity by hypoxia. J. Biol. Chem., 268, 21513-21518.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21513-21518
    • Wang, G.L.1    Semenza, G.L.2
  • 76
    • 0028816847 scopus 로고
    • Purification and characterisation of hypoxia inducible factor-1
    • WANG GL AND SEMENZA GL. (1995). Purification and characterisation of hypoxia inducible factor-1. J. Biol. Chem., 270, 1230-1237.
    • (1995) J. Biol. Chem. , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 79
    • 0029052335 scopus 로고
    • Induction of interleukin 6(IL-6) by hypoxia in vascular cells central role of the binding site for nuclear factor-IL-6
    • YAN SF, TRITTO I, PINSKY D, LIAO H, HUANG J, FULLER G, BRETT J, MAY L AND STERN D. (1995). Induction of interleukin 6(IL-6) by hypoxia in vascular cells central role of the binding site for nuclear factor-IL-6. J. Biol. Chem., 270, 11463-11471.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11463-11471
    • Yan, S.F.1    Tritto, I.2    Pinsky, D.3    Liao, H.4    Huang, J.5    Fuller, G.6    Brett, J.7    May, L.8    Stern, D.9
  • 80
    • 0028978712 scopus 로고
    • Involvement of NF-κB in the induction of NAD(P)H:quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C
    • YAO K-S AND O'DWYER PJ. (1995). Involvement of NF-κB in the induction of NAD(P)H:quinone oxidoreductase (DT-diaphorase) by hypoxia, oltipraz and mitomycin C. Biochem. Pharmacol., 49, 275-282.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 275-282
    • Yao, K.-S.1    O'Dwyer, P.J.2
  • 81
    • 0027936404 scopus 로고
    • Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia
    • YAO KS, XANTHOUDAKIS S, CURRAN T AND O'DWYER PJ. (1994a). Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia. Mol. Cell. Biol., 14, 5997-6003.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5997-6003
    • Yao, K.S.1    Xanthoudakis, S.2    Curran, T.3    O'Dwyer, P.J.4
  • 82
    • 0028147101 scopus 로고
    • Interaction of heat and hypoxia in modulating transcription of DT diaphorase in human colon adenocarcinoma cells
    • YAO K-S, CLAYTON M AND O'DWYER PJ. (1994b). Interaction of heat and hypoxia in modulating transcription of DT diaphorase in human colon adenocarcinoma cells. Cell Growth Different., 5, 125-131.
    • (1994) Cell Growth Different. , vol.5 , pp. 125-131
    • Yao, K.-S.1    Clayton, M.2    O'Dwyer, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.