β-Arrestin1 interacts with the G-protein subunits β1γ 2 and promotes β1γ 2-dependent Akt signalling for NF-κB activation

Biochemical Journal

Volumn 417, Issue 1, 2009, Pages 287-296

  Yang, Ming ^a,c   He, Rong L ^a   Benovic, Jeffrey L ^b   Ye, Richard D ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c CV THERAPEUTICS INC   (United States)

Author keywords

arrestin; Akt; GTP binding protein subunit (G ); Nuclear factor B (NF B)

Indexed keywords

AKT; AKT PHOSPHORYLATION; ARRESTINS; DELETION MUTAGENESIS; G PROTEIN; IN-VITRO; NOVEL FUNCTIONS; NUCLEAR FACTORS; NUCLEAR TRANSLOCATIONS; OVER-EXPRESSION; SMALL INTERFERING RNA; TRANSFECTED CELLS;

AMINES; AMINO ACIDS; NUCLEIC ACIDS; ORGANIC ACIDS; RNA; TRANSCRIPTION FACTORS;

PLANTS (BOTANY);

BETA ARRESTIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN BETA1GAMMA2 SUBUNIT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; PROTEIN KINASE B; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BETA ARRESTIN; GNG2 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; RETINA S ANTIGEN;

ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE DELETION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REPORTER GENE; SIGNAL TRANSDUCTION; CELL LINE; GEL MOBILITY SHIFT ASSAY; GENETICS; HELA CELL; IMMUNOPRECIPITATION; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; WESTERN BLOTTING;

ARRESTINS; BLOTTING, WESTERN; CELL LINE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEINS; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; NF-KAPPA B; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SEQUENCE DELETION; SIGNAL TRANSDUCTION;

EID: 58249088830     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20081561     Document Type: Article

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