-
1
-
-
0035050571
-
Resurgence of sodium channel research
-
DOI 10.1146/annurev.physiol.63.1.871
-
Goldin AL. Resurgence of sodium channel research. Annu Rev Physiol 2001;63:871-894 (Pubitemid 32304340)
-
(2001)
Annual Review of Physiology
, vol.63
, pp. 871-894
-
-
Goldin, A.L.1
-
3
-
-
29844438166
-
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
-
Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol Rev 2005;57(4):397-409 • Excellent review providing background on many aspects of VGSCs.
-
(2005)
Pharmacol Rev
, vol.57
, Issue.4
, pp. 397-409
-
-
Catterall, W.A.1
Goldin, A.L.2
Waxman, S.G.3
-
4
-
-
0032476061
-
AKAP15 anchors cAMP-dependent protein kinase to brain sodium channels
-
DOI 10.1074/jbc.273.40.25783
-
Tibbs VC, Gray PC, Catterall WA, Murphy BJ. AKAP15 anchors cAMP-dependent protein kinase to brain sodium channels. J Biol Chem 1998;273(40):25783-25788 (Pubitemid 28475805)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.40
, pp. 25783-25788
-
-
Tibbs, V.C.1
Gray, P.C.2
Catterall, W.A.3
Murphy, B.J.4
-
5
-
-
0036395114
-
+ channels by protein kinase C and protein kinase a anchored to AKAP-15
-
DOI 10.1006/mcne.2002.1162
-
Cantrell AR, Tibbs VC, Yu FH, et al. Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15. Mol Cell Neurosci 2002;21(1):63-80 (Pubitemid 35178500)
-
(2002)
Molecular and Cellular Neuroscience
, vol.21
, Issue.1
, pp. 63-80
-
-
Cantrell, A.R.1
Tibbs, V.C.2
Yu, F.H.3
Murphy, B.J.4
Sharp, E.M.5
Qu, Y.6
Catterall, W.A.7
Scheuer, T.8
-
6
-
-
33845195005
-
Regulation of sodium and calcium channels by signaling complexes
-
DOI 10.1080/10799890600915100, PII M8M6672365751078
-
Catterall WA, Hulme JT, Jiang X, Few WP. Regulation of sodium and calcium channels by signaling complexes. J Recept Signal Transduct Res 2006;26(5-6):577-598 (Pubitemid 44849906)
-
(2006)
Journal of Receptors and Signal Transduction
, vol.26
, Issue.5-6
, pp. 577-598
-
-
Catterall, W.A.1
Hulme, J.T.2
Jiang, X.3
Few, W.P.4
-
7
-
-
0039552118
-
Solution structure of the sodium channel inactivation gate
-
DOI 10.1021/bi9823380
-
Rohl CA, Boeckman FA, Baker C, et al. Solution structure of the sodium channel inactivation gate. Biochemistry 1999;38(3):855-861 (Pubitemid 29052698)
-
(1999)
Biochemistry
, vol.38
, Issue.3
, pp. 855-861
-
-
Rohl, C.A.1
Boeckman, F.A.2
Baker, C.3
Scheuer, T.4
Catterall, W.A.5
Klevit, R.E.6
-
8
-
-
34347271334
-
Sodium channel auxiliary subunits
-
DOI 10.1159/000099646
-
Tseng TT, McMahon AM, Johnson VT, et al. Sodium channel auxiliary subunits. J Mol Microbiol Biotechnol 2007;12(3-4):249-262 (Pubitemid 46991598)
-
(2007)
Journal of Molecular Microbiology and Biotechnology
, vol.12
, Issue.3-4
, pp. 249-262
-
-
Tseng, T.-T.1
McMahon, A.M.2
Johnson, V.T.3
Mangubat, E.Z.4
Zahm, R.J.5
Pacold, M.E.6
Jakobsson, E.7
-
10
-
-
0030608445
-
Spinal sensory neurons express multiple sodium channel α-subunit mRNAs
-
DOI 10.1016/S0169-328X(96)00163-5, PII S0169328X96001635
-
Black JA, Dib-Hajj S, McNabola K, et al. Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs. Brain Res Mol Brain Res 1996;43(1-2):117-131 • Very important study, one of the first to describe the diversity of VGSCs in DRGs. (Pubitemid 27042398)
-
(1996)
Molecular Brain Research
, vol.43
, Issue.1-2
, pp. 117-131
-
-
Black, J.A.1
Dib-Hajj, S.2
McNabola, K.3
Jeste, S.4
Rizzo, M.A.5
Kocsis, J.D.6
Waxman, S.G.7
-
11
-
-
0032723079
-
Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain
-
Dib-Hajj SD, Fjell J, Cummins TR, et al. Plasticity of sodium channel expression in DRG neurons in the chronic constriction injury model of neuropathic pain. Pain 1999;83(3):591-600
-
(1999)
Pain
, vol.83
, Issue.3
, pp. 591-600
-
-
Dib-Hajj, S.D.1
Fjell, J.2
Cummins, T.R.3
-
12
-
-
0027933696
-
Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy
-
Waxman SG, Kocsis JD, Black JA. Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy. J Neurophysiol 1994;72(1):466-470 (Pubitemid 24233666)
-
(1994)
Journal of Neurophysiology
, vol.72
, Issue.1
, pp. 466-470
-
-
Waxman, S.G.1
Kocsis, J.D.2
Black, J.A.3
-
13
-
-
0030997916
-
Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury
-
Cummins TR, Waxman SG. Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury. J Neurosci 1997;17(10):3503-3514 (Pubitemid 27200579)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.10
, pp. 3503-3514
-
-
Cummins, T.R.1
Waxman, S.G.2
-
14
-
-
28844448678
-
V1.3 expression and neuropathic pain behavior in rats
-
DOI 10.1016/j.pain.2005.05.027, PII S0304395905002678
-
Lindia JA, Köhler MG, Martin WJ, Abbadie C. Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats. Pain 2005;117(1-2):145-153 (Pubitemid 41764782)
-
(2005)
Pain
, vol.117
, Issue.1-2
, pp. 145-153
-
-
Lindia, J.A.1
Kohler, M.G.2
Martin, W.J.3
Abbadie, C.4
-
15
-
-
33751014049
-
v 1.3 null mutant mice
-
DOI 10.1186/1744-8069-2-33
-
Nassar MA, Baker MD, Levato A, et al. Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. Mol Pain 2006;2:33 doi:10.1186/1744-8069-2-33 (Pubitemid 44741732)
-
(2006)
Molecular Pain
, vol.2
, pp. 33
-
-
Nassar, M.A.1
Baker, M.D.2
Levato, A.3
Ingram, R.4
Mallucci, G.5
McMahon, S.B.6
Wood, J.N.7
-
16
-
-
0035882277
-
Nav1.3 sodium channels: Rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons
-
Cummins TR, Aglieco F, Renganathan M, et al. Nav1.3 sodium channels: rapid repriming and slow closed-state inactivation display quantitative differences after expression in a mammalian cell line and in spinal sensory neurons. J Neurosci 2001;21(16):5952-5961 (Pubitemid 32737728)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.16
, pp. 5952-5961
-
-
Cummins, T.R.1
Aglieco, F.2
Renganathan, M.3
Herzog, R.I.4
Dib-Hajj, S.D.5
Waxman, S.G.6
-
17
-
-
0034523226
-
Cloning, distribution and functional analysis of the type III sodium channel from human brain
-
DOI 10.1046/j.1460-9568.2000.01336.x
-
Chen YH, Dale TJ, Romanos MA, et al. Cloning, distribution and functional analysis of the type III sodium channel from human brain. Eur J Neurosci 2000;12(12):4281-4289 (Pubitemid 32040926)
-
(2000)
European Journal of Neuroscience
, vol.12
, Issue.12
, pp. 4281-4289
-
-
Yu Hua, C.1
Dale, T.J.2
Romanos, M.A.3
Whitaker, W.R.J.4
Xin Min, X.5
Clare, J.J.6
-
18
-
-
0035977980
-
Comparative distribution of voltage-gated sodium channel proteins in human brain
-
DOI 10.1016/S0169-328X(00)00289-8, PII S0169328X00002898
-
Whitaker WR, Faull RL, Waldvogel HJ, et al. Comparative distribution of voltage-gated sodium channel proteins in human brain. Brain Res Mol Brain Res 2001;88(1-2):37-53 (Pubitemid 32274258)
-
(2001)
Molecular Brain Research
, vol.88
, Issue.1-2
, pp. 37-53
-
-
Whitaker, W.R.J.1
Faull, R.L.M.2
Waldvogel, H.J.3
Plumpton, C.J.4
Emson, P.C.5
Clare, J.J.6
-
19
-
-
0034686371
-
Distribution of voltage-gated sodium channel α-subunit and β-subunit mRNAs in human hippocampal formation, cortex, and cerebellum
-
DOI 10.1002/(SICI)1096-9861(20000619)422:1<123::AID-CNE8>3.0.CO;2-X
-
Whitaker WR, Clare JJ, Powell AJ, et al. Distribution of voltage-gated sodium channel alpha-subunit and beta-subunit mRNAs in human hippocampal formation, cortex, and cerebellum. J Comp Neurol 2000;422(1):123-139 (Pubitemid 30346568)
-
(2000)
Journal of Comparative Neurology
, vol.422
, Issue.1
, pp. 123-139
-
-
Whitaker, W.R.J.1
Clare, J.J.2
Powell, A.J.3
Chen, Y.H.4
Faull, R.L.M.5
Emson, P.C.6
-
20
-
-
0141529982
-
v1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury
-
Hains BC, Klein JP, Saab CY, et al. Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury. J Neurosci 2003;23(26):8881-8892 (Pubitemid 37210901)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.26
, pp. 8881-8892
-
-
Hains, B.C.1
Klein, J.P.2
Saab, C.Y.3
Craner, M.J.4
Black, J.A.5
Waxman, S.G.6
-
21
-
-
4344670206
-
v 1.7 (PN1) in acute and inflammatory pain
-
DOI 10.1073/pnas.0404915101
-
Nassar MA, Stirling LC, Forlani G, et al. Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain. Proc Natl Acad Sci USA 2004;101(34):12706-12711 (Pubitemid 39122087)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.34
, pp. 12706-12711
-
-
Nassar, M.A.1
Stirling, L.C.2
Forlani, G.3
Baker, M.D.4
Matthewst, E.A.5
Dickenson, A.H.6
Wood, J.N.7
-
22
-
-
33845187874
-
Neuropathic pain develops normally in mice lacking both Nav1.7 and Nav1.8
-
doi:10.1186/1744-8069-1-24
-
Nassar MA, Levato A, Stirling LC, Wood JN. Neuropathic pain develops normally in mice lacking both Nav1.7 and Nav1.8. Mol Pain 2005;1:24 doi:10.1186/1744-8069-1-24
-
(2005)
Mol Pain
, vol.1
, pp. 24
-
-
Nassar, M.A.1
Levato, A.2
Stirling, L.C.3
Wood, J.N.4
-
23
-
-
43749121619
-
Nav1.7 expression is increased in painful human dental pulp
-
DOI 10.1186/1744-8069-4-16
-
Luo S, Perry GM, Levinson SR, Henry MA. Nav1.7 expression is increased in painful human dental pulp. Mol Pain 2008;4:16 doi:10.1186/1744-8069-4-16 (Pubitemid 351689722)
-
(2008)
Molecular Pain
, vol.4
, pp. 16
-
-
Luo, S.1
Perry, G.M.2
Levinson, S.R.3
Henry, M.A.4
-
24
-
-
41849102427
-
Increased nerve fiber expression of sensory sodium channels Nav1.7, Nav1.8, and Nav1.9 in rhinitis
-
Keh SM, Facer P, Simpson KD, et al. Increased nerve fiber expression of sensory sodium channels Nav1.7, Nav1.8, and Nav1.9 in rhinitis. Laryngoscope 2008;118(4):573-579
-
(2008)
Laryngoscope
, vol.118
, Issue.4
, pp. 573-579
-
-
Keh, S.M.1
Facer, P.2
Simpson, K.D.3
-
25
-
-
0024419576
-
Long-term course in congenital analgesia
-
Losa M, Scheier H, Rohner P, et al. Long-term course in congenital analgesia Schweiz Med Wochenschr 1989;119(38):1303-1308
-
(1989)
Schweiz Med Wochenschr
, vol.119
, Issue.38
, pp. 1303-1308
-
-
Losa, M.1
Scheier, H.2
Rohner, P.3
-
26
-
-
0029076187
-
Congenital indifference to pain: Long-term follow-up of two cases
-
Hirsch E, Moye D, Dimon JH III. Congenital indifference to pain: long-term follow-up of two cases. South Med J 1995;88(8):851-857
-
(1995)
South Med J
, vol.88
, Issue.8
, pp. 851-857
-
-
Hirsch, E.1
Moye, D.2
Dimon III, J.H.3
-
27
-
-
0000282772
-
A case of congenital pure analgesia
-
Dearborn GVN. A case of congenital pure analgesia. Nerv Ment Dis 1932;75;612-615 • One of the earliest clinical descriptions of CIP. Very worthwhile reading because of the colourful description of the condition.
-
(1932)
Nerv Ment Dis
, vol.75
, pp. 612-615
-
-
Dearborn, G.V.N.1
-
29
-
-
33845901486
-
An SCN9A channelopathy causes congenital inability to experience pain
-
DOI 10.1038/nature05413, PII NATURE05413
-
Cox JJ, Reimann F, Nicholas AK, et al. An SCN9A channelopathy causes congenital inability to experience pain. Nature 2006;444(7121):894-898 •• Very important paper, the first description of the genetic basis of CIP linking it to mutations in Nav1.7. (Pubitemid 46024997)
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 894-898
-
-
Cox, J.J.1
Reimann, F.2
Nicholas, A.K.3
Thornton, G.4
Roberts, E.5
Springell, K.6
Karbani, G.7
Jafri, H.8
Mannan, J.9
Raashid, Y.10
Al-Gazali, L.11
Hamamy, H.12
Valente, E.M.13
Gorman, S.14
Williams, R.15
McHale, D.P.16
Wood, J.N.17
Gribble, F.M.18
Woods, C.G.19
-
30
-
-
34247874778
-
v1.7 gene underlie congenital indifference to pain in multiple human populations
-
DOI 10.1111/j.1399-0004.2007.00790.x
-
Goldberg YP, MacFarlane J, MacDonald ML, et al. Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations. Clin Genet 2007;71(4):311-19 •• Similar to the Cox et al. study [29] but more extensive, including data from nine families of seven different nationalities. (Pubitemid 46690905)
-
(2007)
Clinical Genetics
, vol.71
, Issue.4
, pp. 311-319
-
-
Goldberg, Y.P.1
Macfarlane, J.2
Macdonald, M.L.3
Thompson, J.4
Dube, M.P.5
Mattice, M.6
Fraser, R.7
Young, C.8
Hossain, S.9
Pape, T.10
Payne, B.11
Radomski, C.12
Donaldson, G.13
Ives, E.14
Cox, J.15
Younghusband, H.B.16
Green, R.17
Duff, A.18
Boltshauser, E.19
Grinspan, G.A.20
Dimon, J.H.21
Sibley, B.G.22
Andria, G.23
Toscano, E.24
Kerdraon, J.25
Bowsher, D.26
Pimstone, S.N.27
Samuels, M.E.28
Sherrington, R.29
Hayden, M.R.30
more..
-
31
-
-
34548419652
-
A stop codon mutation in SCN9A causes lack of pain sensation
-
DOI 10.1093/hmg/ddm160
-
Ahmad S, Dahllund L, Eriksson AB, et al. A stop codon mutation in SCN9A causes lack of pain sensation. Hum Mol Genet 2007;16(17):2114-2121 (Pubitemid 47354894)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.17
, pp. 2114-2121
-
-
Ahmad, S.1
Dahllund, L.2
Eriksson, A.B.3
Hellgren, D.4
Karlsson, U.5
Lund, P.-E.6
Meijer, I.A.7
Meury, L.8
Mills, T.9
Moody, A.10
Morinville, A.11
Morten, J.12
O'Donnell, D.13
Raynoschek, C.14
Salter, H.15
Rouleau, G.A.16
Krupp, J.J.17
-
32
-
-
0000192746
-
Erythromelalgia and other disturbances of the extremities accompanied by vasodilatation and burning
-
Brown GF. Erythromelalgia and other disturbances of the extremities accompanied by vasodilatation and burning. Am J Med Sci 1932;183:468-485
-
(1932)
Am J Med Sci
, vol.183
, pp. 468-485
-
-
Brown, G.F.1
-
33
-
-
67649349452
-
Erythermalgia; report of a case, and response to a new therapeutic approach
-
Widmann RR. Erythermalgia; report of a case, and response to a new therapeutic approach. Calif Med 1949;71(5):356-359
-
(1949)
Calif Med
, vol.71
, Issue.5
, pp. 356-359
-
-
Widmann, R.R.1
-
35
-
-
0026773355
-
Clinical characteristics and pathophysiology of erythromelalgia and erythermalgia
-
Drenth JP, Michiels JJ. Clinical characteristics and pathophysiology of erythromelalgia and erythermalgia. Am J Med 1992;93(1):111-114
-
(1992)
Am J Med
, vol.93
, Issue.1
, pp. 111-114
-
-
Drenth, J.P.1
Michiels, J.J.2
-
36
-
-
41149172710
-
Primary erythermalgia as a sodium channelopathy: Screening for SCN9A mutations: exclusion of a causal role of SCN10A and SCN11A
-
Drenth JP, Te Morsche RH, Mansour S, Mortimer PS. Primary erythermalgia as a sodium channelopathy: screening for SCN9A mutations: exclusion of a causal role of SCN10A and SCN11A. Arch Dermatol 2008;144(3):320-324
-
(2008)
Arch Dermatol
, vol.144
, Issue.3
, pp. 320-324
-
-
Drenth, J.P.1
Te Morsche, R.H.2
Mansour, S.3
Mortimer, P.S.4
-
37
-
-
4644268452
-
v1.7 sodium channels in a painful inherited neuropathy
-
DOI 10.1523/JNEUROSCI.2695-04.2004
-
Cummins TR, Dib-Hajj SD, Waxman SG. Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy. J Neurosci 2004;24(38):8232-8236 • One of the first studies demonstrating the effects of erythermalgia mutations on biophysical properties of Nav1.7 currents. (Pubitemid 39280802)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.38
, pp. 8232-8236
-
-
Cummins, T.R.1
Dib-Hajj, S.D.2
Waxman, S.G.3
-
38
-
-
23444443202
-
v1.7 in familial erythromelalgia induces bursting of sensory neurons
-
DOI 10.1093/brain/awh514
-
Dib-Hajj SD, Rush AM, Cummins TR, et al. Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons. Brain 2005;128(8):1847-1854 • Biophysical study showing the effect of erythermalgia mutants on DRG excitability. (Pubitemid 41373656)
-
(2005)
Brain
, vol.128
, Issue.8
, pp. 1847-1854
-
-
Dib-Hajj, S.D.1
Rush, A.M.2
Cummins, T.R.3
Hisama, F.M.4
Novella, S.5
Tyrrell, L.6
Marshall, L.7
Waxman, S.G.8
-
39
-
-
26444466085
-
Autosomal dominant erythermalgia associated with a novel mutation in the voltage-gated sodium channel alpha subunit Nav1.7
-
Michiels JJ, te Morsche RH, Jansen JB, Drenth JP. Autosomal dominant erythermalgia associated with a novel mutation in the voltage-gated sodium channel alpha subunit Nav1.7. Arch Neurol 2005;62(10):1587-1590
-
(2005)
Arch Neurol
, vol.62
, Issue.10
, pp. 1587-1590
-
-
Michiels, J.J.1
Te Morsche, R.H.2
Jansen, J.B.3
Drenth, J.P.4
-
40
-
-
33846021646
-
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating
-
DOI 10.1074/jbc.M607637200
-
Lampert A, Dib-Hajj SD, Tyrrell L, Waxman SG. Size matters: erythromelalgia mutation S241T in Nav1.7 alters channel gating. J Biol Chem 2006;281(47):36029-36035 (Pubitemid 46041336)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.47
, pp. 36029-36035
-
-
Lampert, A.1
Dib-Hajj, S.D.2
Tyrrell, L.3
Waxman, S.G.4
-
41
-
-
33750976383
-
Inherited erythermalgia: Limb pain from an S4 charge-neutral Na channelopathy
-
DOI 10.1212/01.wnl.0000231514.33603.1e, PII 0000611420061114000010
-
Choi JS, Dib-Hajj SD, Waxman SG. Inherited erythermalgia: limb pain from an S4 charge-neutral Na channelopathy. Neurology 2006;67(9):1563-1567 (Pubitemid 44747924)
-
(2006)
Neurology
, vol.67
, Issue.9
, pp. 1563-1567
-
-
Choi, J.-S.1
Dib-Hajj, S.D.2
Waxman, S.G.3
-
42
-
-
33845271929
-
Na(V)1.7 mutant A863P in erythromelalgia: Effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons
-
Harty TP, Dib-Hajj SD, Tyrrell L, et al. Na(V)1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons. J Neurosci 2006;26(48):12566-12575
-
(2006)
J Neurosci
, vol.26
, Issue.48
, pp. 12566-12575
-
-
Harty, T.P.1
Dib-Hajj, S.D.2
Tyrrell, L.3
-
43
-
-
53049098906
-
A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation
-
Epub ahead of print
-
Lampert A, O'Reilly AO, Dib-Hajj SD, et al. A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation. J Biol Chem 2008;283(35):24118-24127 [Epub ahead of print]
-
(2008)
J Biol Chem
, vol.283
, Issue.35
, pp. 24118-24127
-
-
Lampert, A.1
O'Reilly, A.O.2
Dib-Hajj, S.D.3
-
44
-
-
40449087926
-
Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decade
-
doi:10.1186/1744-8069-4-1
-
Cheng X, Dib-Hajj SD, Tyrrell L, Waxman SG. Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decade. Mol Pain 2008;4:1 doi:10.1186/1744- 8069-4-1
-
(2008)
Mol Pain
, Issue.4
, pp. 1
-
-
Cheng, X.1
Dib-Hajj, S.D.2
Tyrrell, L.3
Waxman, S.G.4
-
45
-
-
33644826050
-
v1.7
-
DOI 10.1002/ana.20776
-
Han C, Rush AM, Dib-Hajj SD, et al. Sporadic onset of erythermalgia: a gain-of-function mutation in Nav1.7. Ann Neurol 2006;59(3):553-558 (Pubitemid 43358077)
-
(2006)
Annals of Neurology
, vol.59
, Issue.3
, pp. 553-558
-
-
Han, C.1
Rush, A.M.2
Dib-Hajj, S.D.3
Li, S.4
Xu, Z.5
Wang, Y.6
Tyrrell, L.7
Wang, X.8
Yang, Y.9
Waxman, S.G.10
-
46
-
-
33846837216
-
Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7
-
DOI 10.1186/1744-8069-3-3
-
Han C, Lampert A, Rush AM, et al. Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7. Mol Pain 2007;3:3 doi:10.1186/1744-8069-3-3 (Pubitemid 46211001)
-
(2007)
Molecular Pain
, vol.3
, pp. 3
-
-
Han, C.1
Lampert, A.2
Rush, A.M.3
Dib-Hajj, S.D.4
Wang, X.5
Yang, Y.6
Waxman, S.G.7
-
47
-
-
34249980057
-
v 1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity
-
DOI 10.1113/jphysiol.2006.127027
-
Sheets PL, Jackson JO II, Waxman SG, et al. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity. J Physiol 2007;581(3):1019-1031 (Pubitemid 46887978)
-
(2007)
Journal of Physiology
, vol.581
, Issue.3
, pp. 1019-1031
-
-
Sheets, P.L.1
Jackson, J.O.2
Waxman, S.G.3
Dib-hajj, S.D.4
Cummins, T.R.5
-
48
-
-
36849036949
-
Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders
-
DOI 10.1172/JCI33297
-
Drenth JP, Waxman SG. Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders. J Clin Invest 2007;117(12):3603-3609 • Excellent review providing state-of-the-art knowledge concerning the Nav1.7 mutations and associated clinical conditions. (Pubitemid 350224065)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3603-3609
-
-
Drenth, J.P.H.1
Waxman, S.G.2
-
49
-
-
0032400799
-
Slow closed-state inactivation: A novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel
-
Cummins TR, Howe JR, Waxman SG. Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel. J Neurosci 1998;18(23):9607-9619 (Pubitemid 28543742)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.23
, pp. 9607-9619
-
-
Cummins, T.R.1
Howe, J.R.2
Waxman, S.G.3
-
50
-
-
33845893561
-
Neurobiology: A channel sets the gain on pain
-
DOI 10.1038/444831a, PII 444831A
-
Waxman SG. Neurobiology: a channel sets the gain on pain. Nature 2006;444(7121):831-832 (Pubitemid 46024984)
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 831-832
-
-
Waxman, S.G.1
-
51
-
-
12644288297
-
Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons
-
DOI 10.1073/pnas.94.4.1527
-
Toledo-Aral JJ, Moss BL, He ZJ, et al. Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons. Proc Natl Acad Sci USA 1997;94(4):1527-1532 (Pubitemid 27087885)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.4
, pp. 1527-1532
-
-
Toledo-Aral, J.J.1
Moss, B.L.2
He, Z.-J.3
Koszowski, A.G.4
Whisenand, T.5
Levinson, S.R.6
Wolf, J.J.7
Silos-Santiago, I.8
Halegoua, S.9
Mandel, G.10
-
52
-
-
33744454923
-
A single sodium channel mutation produces hyper- Or hypoexcitability in different types of neurons
-
DOI 10.1073/pnas.0602813103
-
Rush AM, Dib-Hajj SD, Liu S, et al. A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons. Proc Natl Acad Sci USA 2006;103(21):8245-8250 (Pubitemid 43801083)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.21
, pp. 8245-8250
-
-
Rush, A.M.1
Dib-Hajj, S.D.2
Liu, S.3
Cummins, T.R.4
Black, J.A.5
Waxman, S.G.6
-
53
-
-
0036223978
-
Impaired neurogenic control of skin perfusion in erythromelalgia
-
DOI 10.1046/j.1523-1747.2002.01726.x
-
Mørk C, Kalgaard OM, Kvernebo K. Impaired neurogenic control of skin perfusion in erythromelalgia. J Invest Dermatol 2002;118(4):699-703 (Pubitemid 34309992)
-
(2002)
Journal of Investigative Dermatology
, vol.118
, Issue.4
, pp. 699-703
-
-
Mork, C.1
Kalgaard, O.M.2
Kvernebo, K.3
-
54
-
-
33750440145
-
What's in a name-familial rectal pain syndrome becomes paroxysmal extreme pain disorder [3]
-
DOI 10.1136/jnnp.2006.089664
-
Fertleman CR, Ferrie CD. What's in a name? Familial rectal pain syndrome becomes paroxysmal extreme pain disorder. J Neurol Neurosurg Psychiatry 2006;77(11):1294-1295 (Pubitemid 44654770)
-
(2006)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.77
, Issue.11
, pp. 1294-1295
-
-
Fertleman, C.R.1
Ferrie, C.D.2
-
55
-
-
34548414786
-
Rectal, ocular, and submaxillary pain; a familial autonomic disorder related to proctalgia fugaz: Report of a family
-
Hayden R, Grossman M. Rectal, ocular, and submaxillary pain; a familial autonomic disorder related to proctalgia fugaz: report of a family. AMA J Dis Child 1959;97(4):479-482
-
(1959)
AMA J Dis Child
, vol.97
, Issue.4
, pp. 479-482
-
-
Hayden, R.1
Grossman, M.2
-
56
-
-
34548446384
-
Paroxysmal extreme pain disorder (previously familial rectal pain syndrome)
-
DOI 10.1212/01.wnl.0000268065.16865.5f, PII 0000611420070807000012
-
Fertleman CR, Ferrie CD, Aicardi J, et al. Paroxysmal extreme pain disorder (previously familial rectal pain syndrome). Neurology 2007;69(6):586-595 (Pubitemid 47357266)
-
(2007)
Neurology
, vol.69
, Issue.6
, pp. 586-595
-
-
Fertleman, C.R.1
Ferrie, C.D.2
Aicardi, J.3
Bednarek, N.A.F.4
Eeg-Olofsson, O.5
Elmslie, F.V.6
Griesemer, D.A.7
Goutieres, F.8
Kirkpatrick, M.9
Malmros, I.N.O.10
Pollitzer, M.11
Rossiter, M.12
Roulet-Perez, E.13
Schubert, R.14
Smith, V.V.15
Testard, H.16
Wong, V.17
Stephenson, J.B.P.18
-
57
-
-
0026488158
-
Familial rectal pain: A type of reflex epilepsy?
-
Schubert R, Cracco JB. Familial rectal pain: a type of reflex epilepsy? Ann Neurol 1992;32(6):824-826
-
(1992)
Ann Neurol
, vol.32
, Issue.6
, pp. 824-826
-
-
Schubert, R.1
Cracco, J.B.2
-
58
-
-
35448950791
-
v1.7 innervation in patients with idiopathic rectal hypersensitivity and paroxysmal extreme pain disorder (familial rectal pain)
-
DOI 10.1016/j.neulet.2007.09.027, PII S0304394007010014
-
Yiangou Y, Facer P, Chessell IP, et al. Voltage-gated ion channel Nav1.7 innervation in patients with idiopathic rectal hypersensitivity and paroxysmal extreme pain disorder (familial rectal pain). Neurosci Lett 2007;427(2):77-82 (Pubitemid 47633792)
-
(2007)
Neuroscience Letters
, vol.427
, Issue.2
, pp. 77-82
-
-
Yiangou, Y.1
Facer, P.2
Chessell, I.P.3
Bountra, C.4
Chan, C.5
Fertleman, C.6
Smith, V.7
Anand, P.8
-
59
-
-
33847168937
-
SCN9A Mutations in Paroxysmal Extreme Pain Disorder: Allelic Variants Underlie Distinct Channel Defects and Phenotypes
-
DOI 10.1016/j.neuron.2006.10.006, PII S0896627306008051
-
Fertleman CR, Baker MD, Parker KA, et al. SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron 2006;52(5):767-774 • First description of mutations associated with PEPD. (Pubitemid 44828442)
-
(2006)
Neuron
, vol.52
, Issue.5
, pp. 767-774
-
-
Fertleman, C.R.1
Baker, M.D.2
Parker, K.A.3
Moffatt, S.4
Elmslie, F.V.5
Abrahamsen, B.6
Ostman, J.7
Klugbauer, N.8
Wood, J.N.9
Gardiner, R.M.10
Rees, M.11
-
60
-
-
51749085389
-
Paroxysmal extreme pain disorder mutations within the D3/S4-S5 Linker of Nav1.7 cause moderate destabilization of fast-inactivation
-
Epub ahead of print
-
Jarecki BW, Sheets PL, Jackson Ii JO, Cummins TR. Paroxysmal extreme pain disorder mutations within the D3/S4-S5 Linker of Nav1.7 cause moderate destabilization of fast-inactivation. J Physiol 2008;[Epub ahead of print]
-
(2008)
J Physiol
-
-
Jarecki, B.W.1
Sheets, P.L.2
Jackson Ii, J.O.3
Cummins, T.R.4
-
61
-
-
0030041548
-
A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
-
DOI 10.1038/379257a0
-
Akopian AN, Sivilotti L, Wood JN. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons. Nature 1996;379(6562):257-262 (Pubitemid 26025211)
-
(1996)
Nature
, vol.379
, Issue.6562
, pp. 257-262
-
-
Akopian, A.N.1
Sivilotti, L.2
Wood, J.N.3
-
62
-
-
0033363999
-
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
-
DOI 10.1038/9195
-
Akopian AN, Souslova V, England S, et al. The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nat Neurosci 1999;2(6):541-548 (Pubitemid 30491235)
-
(1999)
Nature Neuroscience
, vol.2
, Issue.6
, pp. 541-548
-
-
Akopian, A.N.1
Souslova, V.2
England, S.3
Okuse, K.4
Ogata, N.5
Ure, J.6
Smith, A.7
Kerr, B.J.8
McMahon, S.B.9
Boyce, S.10
Hill, R.11
Stanfa, L.C.12
Dickenson, A.H.13
Wood, J.N.14
-
63
-
-
0034022325
-
Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2
-
DOI 10.1006/mcne.1999.0828
-
Amaya F, Decosterd I, Samad TA, et al. Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2. Mol Cell Neurosci 2000;15(4):331-342 (Pubitemid 30266270)
-
(2000)
Molecular and Cellular Neurosciences
, vol.15
, Issue.4
, pp. 331-342
-
-
Amaya, F.1
Decosterd, I.2
Samad, T.A.3
Plumpton, C.4
Tate, S.5
Mannion, R.J.6
Costigan, M.7
Woolf, C.J.8
-
64
-
-
0030981180
-
A single serine residue confers tetrodotoxin insensitivity on the rat sensory-neuron-specific sodium channel SNS
-
DOI 10.1016/S0014-5793(97)00479-1, PII S0014579397004791
-
Sivilotti L, Okuse K, Akopian AN, et al. A single serine residue confers tetrodotoxin insensitivity on the rat sensory-neuron-specific sodium channel SNS. FEBS Lett 1997;409(1):49-52 (Pubitemid 27248565)
-
(1997)
FEBS Letters
, vol.409
, Issue.1
, pp. 49-52
-
-
Sivilotti, L.1
Okuse, K.2
Akopian, A.N.3
Moss, S.4
Wood, J.N.5
-
65
-
-
43749118952
-
Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina
-
O'Brien BJ, Caldwell JH, Ehring GR, et al. Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina. J Comp Neurol 2008;508(6):940-951 • This paper describes Nav1.8 and 1.9 in mouse retina. Is this relevant in man, and is it a possible safety concern for compounds active at these channels?
-
(2008)
J Comp Neurol
, vol.508
, Issue.6
, pp. 940-951
-
-
O'Brien, B.J.1
Caldwell, J.H.2
Ehring, G.R.3
-
66
-
-
0027181559
-
+ channels in rat dorsal root ganglia
-
Ogata N, Tatebayashi H. Kinetic analysis of two types of Na+ channels in rat dorsal root ganglia. J Physiol 1993;466:9-37 (Pubitemid 23225215)
-
(1993)
Journal of Physiology
, vol.466
, pp. 9-37
-
-
Ogata, N.1
Tatebayashi, H.2
-
67
-
-
0027414377
-
Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia
-
Elliott AA, Elliott JR. Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia. J Physiol 1993;463:39-56 (Pubitemid 23120575)
-
(1993)
Journal of Physiology
, vol.463
, pp. 39-56
-
-
Elliott, A.A.1
Elliott, J.R.2
-
68
-
-
0032530528
-
Electrophysiological properties of sodium current subtypes in small cells from adult rat dorsal root ganglia
-
DOI 10.1111/j.1469-7793.1998.771bg.x
-
Rush AM, Bräu ME, Elliott AA, Elliott JR. Electrophysiological properties of sodium current subtypes in small cells from adult rat dorsal root ganglia. J Physiol 1998;511(3):771-789 (Pubitemid 28456906)
-
(1998)
Journal of Physiology
, vol.511
, Issue.3
, pp. 771-789
-
-
Rush, A.M.1
Brau, M.E.2
Elliott, A.A.3
Elliott, J.R.4
-
69
-
-
0036895970
-
2+ current in the action potentials of nociceptive sensory neurons
-
Blair NT, Bean BP. Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons. J Neurosci 2002;22(23):10277-10290 (Pubitemid 35416866)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.23
, pp. 10277-10290
-
-
Blair, N.T.1
Bean, B.P.2
-
70
-
-
34250306409
-
v1.8 is essential for pain at low temperatures
-
DOI 10.1038/nature05880, PII NATURE05880
-
Zimmermann K, Leffler A, Babes A, et al. Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures. Nature 2007;447(7146):855-858 (Pubitemid 46920141)
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 855-858
-
-
Zimmermann, K.1
Leffler, A.2
Babes, A.3
Cendan, C.M.4
Carr, R.W.5
Kobayashi, J.-I.6
Nau, C.7
Wood, J.N.8
Reeh, P.W.9
-
71
-
-
0028971440
-
Calcium potentials and tetrodotoxin-resistant sodium potentials in unmyelinated C fibres of biopsied human sural nerve
-
Quasthoff S, Grosskreutz J, Schröder JM, et al. Calcium potentials and tetrodotoxin-resistant sodium potentials in unmyelinated C fibres of biopsied human sural nerve. Neuroscience 1995;69(3):955-965
-
(1995)
Neuroscience
, vol.69
, Issue.3
, pp. 955-965
-
-
Quasthoff, S.1
Grosskreutz, J.2
Schröder, J.M.3
-
72
-
-
0028158691
-
The role of tetrodotoxin-resistant sodium channels of small primary afferent fibers
-
DOI 10.1016/0006-8993(94)91772-8
-
Jeftinija S. The role of tetrodotoxin-resistant sodium channels of small primary afferent fibers. Brain Res 1994;639(1):125-134 (Pubitemid 24067443)
-
(1994)
Brain Research
, vol.639
, Issue.1
, pp. 125-134
-
-
Jeftinija, S.1
-
73
-
-
0032191372
-
Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea
-
DOI 10.1111/j.1469-7793.1998.211bf.x
-
Brock JA, McLachlan EM, Belmonte C. Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea. J Physiol 1998;512(1):211-217 • First description of TTX-resistance generator potentials in the fine terminals of nociceptors. (Pubitemid 28477429)
-
(1998)
Journal of Physiology
, vol.512
, Issue.1
, pp. 211-217
-
-
Brock, J.A.1
McLachlan, E.M.2
Belmonte, C.3
-
74
-
-
0033062951
-
Electrophysiological evidence for tetrodotoxin-resistant sodium channels in slowly conducting dural sensory fibers
-
Strassman AM, Raymond SA. Electrophysiological evidence for tetrodotoxin-resistant sodium channels in slowly conducting dural sensory fibers. J Neurophysiol 1999;81(2):413-424 (Pubitemid 29264489)
-
(1999)
Journal of Neurophysiology
, vol.81
, Issue.2
, pp. 413-424
-
-
Strassman, A.M.1
Raymond, S.A.2
-
75
-
-
0032606082
-
Molecular properties of brain sodium channels: An important target for anticonvulsant drugs
-
Catterall WA. Molecular properties of brain sodium channels: an important target for anticonvulsant drugs. Adv Neurol 1999;79:441-456
-
(1999)
Adv Neurol
, vol.79
, pp. 441-456
-
-
Catterall, W.A.1
-
76
-
-
0029761647
-
2 modulates the tetrodotoxin-resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP-protein kinase a cascade
-
England S, Bevan S, Docherty RJ. PGE2 modulates the tetrodotoxin- resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP-protein kinase A cascade. J Physiol 1996;495(2):429-440 (Pubitemid 26331824)
-
(1996)
Journal of Physiology
, vol.495
, Issue.2
, pp. 429-440
-
-
England, S.1
Bevan, S.2
Docherty, R.J.3
-
77
-
-
0030054145
-
+ current in nociceptors
-
DOI 10.1073/pnas.93.3.1108
-
Gold MS, Reichling DB, Shuster MJ, Levine JD. Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors. Proc Natl Acad Sci USA 1996;93(3):1108-1112 (Pubitemid 26052849)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.3
, pp. 1108-1112
-
-
Gold, M.S.1
Reichling, D.B.2
Shuster, M.J.3
Levine, J.D.4
-
78
-
-
0033560866
-
CAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS
-
DOI 10.1111/j.1469-7793.1999.0433v.x
-
Fitzgerald EM, Okuse K, Wood JN, et al. cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS. J Physiol 1999;516(2):433-446 (Pubitemid 29204448)
-
(1999)
Journal of Physiology
, vol.516
, Issue.2
, pp. 433-446
-
-
Fitzgerald, E.M.1
Okuse, K.2
Wood, J.N.3
Dolphin, A.C.4
Moss, S.J.5
-
79
-
-
0032535602
-
2- Induced sensitization of rat sensory neurons in vitro
-
Gold MS, Levine JD, Correa AM. Modulation of TTX-R INa by PKC and PKA and their role in PGE2-induced sensitization of rat sensory neurons in vitro. J Neurosci 1998;18(24):10345-10355 (Pubitemid 29016554)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.24
, pp. 10345-10355
-
-
Gold, M.S.1
Levine, J.D.2
Correa, A.M.3
-
80
-
-
41149153802
-
Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons
-
Hudmon A, Choi JS, Tyrrell L, et al. Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons. J Neurosci 2008;28(12):3190-3201
-
(2008)
J Neurosci
, vol.28
, Issue.12
, pp. 3190-3201
-
-
Hudmon, A.1
Choi, J.S.2
Tyrrell, L.3
-
81
-
-
43049116097
-
TTX-R Na+ current-reduction by celecoxib correlates with changes in PGE2; and CGRP within rat DRG neurons during acute incisional pain
-
Ma K, Zhou QH, Chen J, et al. TTX-R Na+ current-reduction by celecoxib correlates with changes in PGE2; and CGRP within rat DRG neurons during acute incisional pain. Brain Res 2008;1209:57-64
-
(2008)
Brain Res
, vol.1209
, pp. 57-64
-
-
Ma, K.1
Zhou, Q.H.2
Chen, J.3
-
82
-
-
67649315930
-
Molecular basis of peripheral hyperalgesia
-
Wood JN, editor. New York: Wiley-Liss
-
England S. Molecular basis of peripheral hyperalgesia. In: Wood JN, editor. Molecular basis of pain induction. New York: Wiley-Liss; 2000; p. 261-287
-
(2000)
Molecular Basis of Pain Induction
, pp. 261-287
-
-
England, S.1
-
83
-
-
48749123103
-
The cell and molecular basis of mechanical, cold, and inflammatory pain
-
Abrahamsen B, Zhao J, Asante CO, et al. The cell and molecular basis of mechanical, cold, and inflammatory pain. Science 2008;321(5889):702-705 • Authors used diphtheria toxin to selectively ablate Nav1.8-expressing nociceptors. Probably provides more useful information than conditional knockouts due to channel plasticity observed using conventional knockout approaches.
-
(2008)
Science
, vol.321
, Issue.5889
, pp. 702-705
-
-
Abrahamsen, B.1
Zhao, J.2
Asante, C.O.3
-
84
-
-
0036145275
-
Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8
-
DOI 10.1016/S0304-3959(01)00391-8, PII S0304395901003918
-
Lai J, Gold MS, Kim CS, et al. Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8. Pain 2002;95(1-2):143-152 (Pubitemid 34076786)
-
(2002)
Pain
, vol.95
, Issue.1-2
, pp. 143-152
-
-
Lai, J.1
Gold, M.S.2
Kim, C.-S.3
Biana, D.4
Ossipov, M.H.5
Hunterc, J.C.6
Porreca, F.7
-
85
-
-
0031840375
-
Rescue of α-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo
-
Dib-Hajj SD, Black JA, Cummins TR, et al. Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo. J Neurophysiol 1998;79(5):2668-2676 (Pubitemid 28261650)
-
(1998)
Journal of Neurophysiology
, vol.79
, Issue.5
, pp. 2668-2676
-
-
Dib-Hajj, S.D.1
Black, J.A.2
Cummins, T.R.3
Kenney, A.M.4
Kocsis, J.D.5
Waxman, S.G.6
-
86
-
-
0033062955
-
In vivo NGF deprivation reduces SNS expression and TTX-R sodium currents in IB4-negative DRG neurons
-
Fjell J, Cummins TR, Fried K, et al. In vivo NGF deprivation reduces SNS expression and TTX-R sodium currents in IB4-negative DRG neurons. J Neurophysiol 1999;81(2):803-810
-
(1999)
J Neurophysiol
, vol.81
, Issue.2
, pp. 803-810
-
-
Fjell, J.1
Cummins, T.R.2
Fried, K.3
-
87
-
-
0033168499
-
Sodium channel expression in NGF-overexpressing transgenic mice
-
DOI 10.1002/(SICI)1097-4547(19990701)57:1<39::AID-JNR5>3.0.CO;2-M
-
Fjell J, Cummins TR, Davis BM, et al. Sodium channel expression in NGF-overexpressing transgenic mice. J Neurosci Res 1999;57(1):39-47 (Pubitemid 29293578)
-
(1999)
Journal of Neuroscience Research
, vol.57
, Issue.1
, pp. 39-47
-
-
Fjell, J.1
Cummins, T.R.2
Davis, B.M.3
Albers, K.M.4
Fried, K.5
Waxman, S.G.6
Black, J.A.7
-
88
-
-
0033955244
-
Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states
-
DOI 10.1016/S0304-3959(99)00251-1, PII S0304395999002511
-
Coward K, Plumpton C, Facer P, et al. Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states. Pain 2000;85(1-2):41-50 (Pubitemid 30110742)
-
(2000)
Pain
, vol.85
, Issue.1-2
, pp. 41-50
-
-
Coward, K.1
Plumpton, C.2
Facer, P.3
Birch, R.4
Carlstedt, T.5
Tate, S.6
Bountra, C.7
Anand, P.8
-
89
-
-
0035809303
-
Sodium channel β1 and β2 subunits parallel SNS/PN3 α-subunit changes in injured human sensory neurons
-
Coward K, Jowett A, Plumpton C, et al. Sodium channel beta1 and beta2 subunits parallel SNS/PN3 alpha-subunit changes in injured human sensory neurons. Neuroreport 2001;12(3):483-488 (Pubitemid 32173952)
-
(2001)
NeuroReport
, vol.12
, Issue.3
, pp. 483-488
-
-
Coward, K.1
Jowett, A.2
Plumpton, C.3
Powell, A.4
Birch, R.5
Tate, S.6
Bountra, C.7
Anand, P.8
-
90
-
-
23944501347
-
v1.8 immunoreactivity in painful human dental pulp
-
DOI 10.1186/1472-6831-5-5
-
Renton T, Yiangou Y, Plumpton C, et al. Sodium channel Nav1.8 immunoreactivity in painful human dental pulp. BMC Oral Health 2005;5:5 doi:10.1186/1472-6831-5-5 (Pubitemid 41185293)
-
(2005)
BMC Oral Health
, vol.5
, pp. 5
-
-
Renton, T.1
Yiangou, Y.2
Plumpton, C.3
Tate, S.4
Bountra, C.5
Anand, P.6
-
91
-
-
0037081892
-
Nerve fibers in lumbar spine structures and injured spinal roots express the sensory neuron-specific sodium channels SNS/PN3 and NaN/SNS2
-
DOI 10.1097/00007632-200201150-00003
-
Bucknill AT, Coward K, Plumpton C, et al. Nerve fibers in lumbar spine structures and injured spinal roots express the sensory neuron-specific sodium channels SNS/PN3 and NaN/SNS2. Spine 2002;27(2):135-140 (Pubitemid 34215551)
-
(2002)
Spine
, vol.27
, Issue.2
, pp. 135-140
-
-
Bucknill, A.T.1
Coward, K.2
Plumpton, C.3
Tate, S.4
Bountra, C.5
Birch, R.6
Sandison, A.7
Hughes, S.P.F.8
Anand, P.9
-
92
-
-
0032555278
-
NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy
-
DOI 10.1073/pnas.95.15.8963
-
Dib-Hajj SD, Tyrrell L, Black JA, Waxman SG. NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy. Proc Natl Acad Sci USA 1998;95(15):8963-8968 (Pubitemid 28350597)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.15
, pp. 8963-8968
-
-
Dib-Hajj, S.D.1
Tyrrell, L.2
Black, J.A.3
Waxman, S.G.4
-
93
-
-
0032755351
-
Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons
-
Dib-Hajj SD, Tyrrell L, Cummins TR, et al. Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons. FEBS Lett 1999;462(1-2):117-120
-
(1999)
FEBS Lett
, vol.462
, Issue.1-2
, pp. 117-120
-
-
Dib-Hajj, S.D.1
Tyrrell, L.2
Cummins, T.R.3
-
94
-
-
0033180098
-
Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn11a encoding the sodium channel NaN
-
DOI 10.1006/geno.1999.5890
-
Dib-Hajj SD, Tyrrell L, Escayg A, et al. Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn11a encoding the sodium channel NaN. Genomics 1999;59(3)309-318 (Pubitemid 29406912)
-
(1999)
Genomics
, vol.59
, Issue.3
, pp. 309-318
-
-
Dib-Hajj, S.D.1
Tyrrell, L.2
Escayg, A.3
Wood, P.M.4
Meisler, M.H.5
Waxman, S.G.6
-
95
-
-
0033572137
-
A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons
-
Cummins TR, Dib-Hajj SD, Black JA, et al. A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons. J Neurosci 1999;19:RC43 1-6
-
(1999)
J Neurosci
, vol.19
-
-
Cummins, T.R.1
Dib-Hajj, S.D.2
Black, J.A.3
-
96
-
-
40849083674
-
Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism
-
Maingret F, Coste B, Padilla F, et al. Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism. J Gen Physiol 2008;131(3):211-225
-
(2008)
J Gen Physiol
, vol.131
, Issue.3
, pp. 211-225
-
-
Maingret, F.1
Coste, B.2
Padilla, F.3
-
97
-
-
0037126309
-
Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9
-
Blum R, Kafitz KW, Konnerth A. Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9. Nature 2002;419(6908):687-693
-
(2002)
Nature
, vol.419
, Issue.6908
, pp. 687-693
-
-
Blum, R.1
Kafitz, K.W.2
Konnerth, A.3
-
98
-
-
39449113609
-
V1.9
-
DOI 10.1113/jphysiol.2007.147942
-
Ostman JA, Nassar MA, Wood JN, Baker MD. GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9. J Physiol 2008;586(4):1077-1087 (Pubitemid 351267347)
-
(2008)
Journal of Physiology
, vol.586
, Issue.4
, pp. 1077-1087
-
-
Ostman, J.A.R.1
Nassar, M.A.2
Wood, J.N.3
Baker, M.D.4
-
99
-
-
21544455502
-
v1.9 to sensory transmission and nociceptive behavior
-
DOI 10.1073/pnas.0501549102
-
Priest BT, Murphy BA, Lindia JA, et al. Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior. Proc Natl Acad Sci USA 2005;102(26):9382-9387 (Pubitemid 40923572)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.26
, pp. 9382-9387
-
-
Priest, B.T.1
Murphy, B.A.2
Lindia, J.A.3
Diaz, C.4
Abbadie, C.5
Ritter, A.M.6
Liberator, P.7
Iyer, L.M.8
Kash, S.F.9
Kohler, M.G.10
Kaczorowski, G.J.11
MacIntyre, D.E.12
Martin, W.J.13
-
100
-
-
34548541493
-
Expression of Nav1.9 channels in human dental pulp and trigeminal ganglion
-
Wells JE, Bingham V, Rowland KC, Hatton J. Expression of Nav1.9 channels in human dental pulp and trigeminal ganglion. J Endod 2007;33(10):1172-1176
-
(2007)
J Endod
, vol.33
, Issue.10
, pp. 1172-1176
-
-
Wells, J.E.1
Bingham, V.2
Rowland, K.C.3
Hatton, J.4
-
101
-
-
0033215996
-
Membrane potential oscillations in dorsal root ganglion neurons: Role in normal electrogenesis and neuropathic pain
-
Amir R, Michaelis M, Devor M. Membrane potential oscillations in dorsal root ganglion neurons: role in normal electrogenesis and neuropathic pain. J Neurosci 1999;19(19):8589-8596 (Pubitemid 30226776)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.19
, pp. 8589-8596
-
-
Amir, R.1
Michaelis, M.2
Devor, M.3
-
102
-
-
39249083820
-
Subthreshold oscillations facilitate neuropathic spike discharge by overcoming membrane accommodation
-
Kovalsky Y, Amir R, Devor M. Subthreshold oscillations facilitate neuropathic spike discharge by overcoming membrane accommodation. Exp Neurol 2008;210(1):194-206
-
(2008)
Exp Neurol
, vol.210
, Issue.1
, pp. 194-206
-
-
Kovalsky, Y.1
Amir, R.2
Devor, M.3
-
103
-
-
30844469806
-
Sodium channels and mechanisms of neuropathic pain
-
DOI 10.1016/j.jpain.2005.09.006, PII S1526590005008904
-
Devor M. Sodium channels and mechanisms of neuropathic pain. J Pain 2006;7(1 Suppl 1):S3-12 • Excellent review concerning VGSCs and their contribution to DRG excitability. (Pubitemid 43106683)
-
(2006)
Journal of Pain
, vol.7
, Issue.1 SUPPL.
-
-
Devor, M.1
-
104
-
-
0037568121
-
Tricyclic antidepressants as long-acting local anesthetics
-
DOI 10.1016/S0304-3959(02)00375-5
-
Sudoh Y, Cahoon EE, Gerner P, Wang GK. Tricyclic antidepressants as long-acting local anesthetics. Pain 2003;103(1-2):49-55 (Pubitemid 36579084)
-
(2003)
Pain
, vol.103
, Issue.1-2
, pp. 49-55
-
-
Sudoh, Y.1
Cahoon, E.E.2
Gerner, P.3
Wang, G.K.4
-
105
-
-
28444445248
-
Systemic administration of local anesthetics to relieve neuropathic pain: A systematic review and meta-analysis
-
DOI 10.1213/01.ANE.0000186348.86792.38
-
Tremont-Lukats IW, Challapalli V, McNicol ED, et al. Systemic administration of local anesthetics to relieve neuropathic pain: a systematic review and meta-analysis. Anesth Analg 2005;101(6):1738-1749 (Pubitemid 41722151)
-
(2005)
Anesthesia and Analgesia
, vol.101
, Issue.6
, pp. 1738-1749
-
-
Tremont-Lukats, I.W.1
Challapalli, V.2
McNicol, E.D.3
Lau, J.4
Carr, D.B.5
-
106
-
-
33644877882
-
Systemic administration of local anesthetic agents to relieve neuropathic pain
-
CD003345
-
Challapalli V, Tremont-Lukats IW, McNicol ED, et al. Systemic administration of local anesthetic agents to relieve neuropathic pain. Cochrane Database Syst Rev 2005;4:CD003345 • Very extensive review of the clinical usage of local anaesthetics in neuropathic pain.
-
(2005)
Cochrane Database Syst Rev
, vol.4
-
-
Challapalli, V.1
Tremont-Lukats, I.W.2
McNicol, E.D.3
-
108
-
-
34249950792
-
Antiepileptic drugs in the treatment of neuropathic pain
-
DOI 10.2165/00003495-200767090-00003
-
Eisenberg E, River Y, Shifrin A, Krivoy N. Antiepileptic drugs in the treatment of neuropathic pain. Drugs 2007;67(9):1265-1289 (Pubitemid 46879094)
-
(2007)
Drugs
, vol.67
, Issue.9
, pp. 1265-1289
-
-
Eisenberg, E.1
River, Y.2
Shifrin, A.3
Krivoy, N.4
-
110
-
-
36949037520
-
Antiepileptic drugs in non-epilepsy disorders: Relations between mechanisms of action and clinical efficacy
-
Johannessen Landmark C. Antiepileptic drugs in non-epilepsy disorders: relations between mechanisms of action and clinical efficacy. CNS Drugs 2008;22(1):27-47 (Pubitemid 350243365)
-
(2008)
CNS Drugs
, vol.22
, Issue.1
, pp. 27-47
-
-
Johannessen Landmark, C.1
-
111
-
-
0016170761
-
Tegretol in the treatment of diabetic neuropathy
-
Wilton TD. Tegretol in the treatment of diabetic neuropathy. S Afr Med J 1974;48(20):869-872
-
(1974)
S Afr Med J
, vol.48
, Issue.20
, pp. 869-872
-
-
Wilton, T.D.1
-
112
-
-
24044458603
-
Oxcarbazepine in painful diabetic neuropathy: A randomized, placebo-controlled study
-
DOI 10.1016/j.ejpain.2004.11.006, PII S1090380104001533
-
Dogra S, Beydoun S, Mazzola J, et al. Oxcarbazepine in painful diabetic neuropathy: a randomized, placebo-controlled study. Eur J Pain 2005;9(5):543-554 (Pubitemid 41219786)
-
(2005)
European Journal of Pain
, vol.9
, Issue.5
, pp. 543-554
-
-
Dogra, S.1
Beydoun, S.2
Mazzola, J.3
Hopwood, M.4
Wan, Y.5
-
113
-
-
26844527371
-
Oxcarbazepine is effective and safe in the treatment of neuropathic pain: Pooled analysis of seven clinical studies
-
DOI 10.1007/s10072-005-0464-z
-
Magenta P, Arghetti S, Di Palma F, et al. Oxcarbazepine is effective and safe in the treatment of neuropathic pain: pooled analysis of seven clinical studies. Neurol Sci 2005;26(4):218-226 (Pubitemid 41447820)
-
(2005)
Neurological Sciences
, vol.26
, Issue.4
, pp. 218-226
-
-
Magenta, P.1
Arghetti, S.2
Di Palma, F.3
Jann, S.4
Sterlicchio, M.5
Bianconi, C.6
Galimberti, V.7
Osio, M.8
Siciliano, G.9
Cavallotti, G.10
Sterzi, R.11
-
114
-
-
33846822012
-
Lamotrigine for treatment of pain associated with diabetic neuropathy: Results of two randomized, double-blind, placebo-controlled studies
-
DOI 10.1016/j.pain.2006.09.040, PII S0304395906005252
-
Vinik AI, Tuchman M, Safirstein B, et al. Lamotrigine for treatment of pain associated with diabetic neuropathy: results of two randomized, double-blind, placebo-controlled studies. Pain 2007;128(1-2):169-179 (Pubitemid 46216610)
-
(2007)
Pain
, vol.128
, Issue.1-2
, pp. 169-179
-
-
Vinik, A.I.1
Tuchman, M.2
Safirstein, B.3
Corder, C.4
Kirby, L.5
Wilks, K.6
Quessy, S.7
Blum, D.8
Grainger, J.9
White, J.10
Silver, M.11
-
115
-
-
0021903373
-
Batrachotoxin as a tool to study voltage-sensitive sodium channels of excitable membranes
-
Khodorov BI. Batrachotoxin as a tool to study voltage-sensitive sodium channels of excitable membranes. Prog Biophys Mol Biol 1985;45(2):57-148
-
(1985)
Prog Biophys Mol Biol
, vol.45
, Issue.2
, pp. 57-148
-
-
Khodorov, B.I.1
-
117
-
-
27844589940
-
Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels
-
DOI 10.1124/mol.105.014803
-
Lipkind GM, Fozzard HA. Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels. Mol Pharmacol 2005;68(6):1611-1622 (Pubitemid 41654345)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.6
, pp. 1611-1622
-
-
Lipkind, G.M.1
Fozzard, H.A.2
-
118
-
-
0017332486
-
Local anesthetics: Hydrophilic and hydrophobic pathways for the drug receptor reaction
-
Hille B. Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J Gen Physiol 1977;69:497-515 (Pubitemid 8086978)
-
(1977)
Journal of General Physiology
, vol.69
, Issue.4
, pp. 497-515
-
-
Hille, B.1
-
119
-
-
0029787945
-
+ channels
-
DOI 10.1073/pnas.93.17.9270
-
Ragsdale DS, McPhee JC, Scheuer T, Catterall WA. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. Proc Natl Acad Sci USA 1996;93(17):9270-9275 (Pubitemid 26282053)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.17
, pp. 9270-9275
-
-
Ragsdale, D.S.1
Mcphee, J.C.2
Scheuer, T.3
Catterall, W.A.4
-
120
-
-
0028179148
-
Kinetic effects of quaternary lidocaine block of cardiac sodium channels: A gating current study
-
Hanck DA, Makielski JC, Sheets MF. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J Gen Physiol 1994;103(1):19-43 (Pubitemid 2041189)
-
(1994)
Journal of General Physiology
, vol.103
, Issue.1
, pp. 19-43
-
-
Hanck, D.A.1
Makielski, J.C.2
Sheets, M.F.3
-
121
-
-
1042266533
-
Potassium, sodium, calcium and glutamate-gated channels: Pore architecture and ligand action
-
Zhorov BS, Tikhonov DB. Potassium, sodium, calcium and glutamate-gated channels: pore architecture and ligand action. J Neurochem 2004;88(4):782-799 (Pubitemid 38199299)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.4
, pp. 782-799
-
-
Zhorov, B.S.1
Tikhonov, D.B.2
-
122
-
-
11244296111
-
Modeling P-loops domain of sodium channel: Homology with potassium channels and interaction with ligands
-
DOI 10.1529/biophysj.104.048173
-
Tikhonov DB, Zhorov BS. Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands. Biophys J 2005;88(1):184-197 (Pubitemid 40070668)
-
(2005)
Biophysical Journal
, vol.88
, Issue.1
, pp. 184-197
-
-
Tikhonov, D.B.1
Zhorov, B.S.2
-
123
-
-
52949104364
-
Access and bnding of local anesthetics in the closed sodium channel
-
Epub ahead of print
-
Bruhova I, Tikhonov DB, Zhorov BS. Access and bnding of local anesthetics in the closed sodium channel. Mol Pharmacol 2008; [Epub ahead of print]
-
(2008)
Mol Pharmacol
-
-
Bruhova, I.1
Tikhonov, D.B.2
Zhorov, B.S.3
-
124
-
-
0028817743
-
Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes
-
Valenzuela C, Snyders DJ, Bennett PB, et al. Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes. Circulation 1995;92(10):3014-3024
-
(1995)
Circulation
, vol.92
, Issue.10
, pp. 3014-3024
-
-
Valenzuela, C.1
Snyders, D.J.2
Bennett, P.B.3
-
125
-
-
0030819261
-
Molecular determinants of stereoselective bupivacaine block of hKv1.5 channels
-
Franqueza L, Longobardo M, Vicente J, et al. Molecular determinants of stereoselective bupivacaine block of hKv1.5 channels. Circ Res 1997;81(6):1053-1064 (Pubitemid 27514956)
-
(1997)
Circulation Research
, vol.81
, Issue.6
, pp. 1053-1064
-
-
Franqueza, L.1
Longobardo, M.2
Vicente, J.3
Delpon, E.4
Tamkun, M.M.5
Tamargo, J.6
Snyders, D.J.7
Valenzuela, C.8
-
126
-
-
0034016346
-
+ currents
-
Longobardo M, González T, Navarro-Polanco R, et al. Effects of a quaternary bupivacaine derivative on delayed rectifier K(+) currents. Br J Pharmacol 2000;130(2):391-401 (Pubitemid 30261051)
-
(2000)
British Journal of Pharmacology
, vol.130
, Issue.2
, pp. 391-401
-
-
Longobardo, M.1
Gonzalez, T.2
Navarro-Polanco, R.3
Caballero, R.4
Delpon, E.5
Tamargo, J.6
Snyders, D.J.7
Tamkun, M.M.8
Valenzuela, C.9
-
127
-
-
0036273270
-
Bupivacaine inhibits human neuronal Kv3 channels in SH-SY5Y human neuroblastoma cells
-
DOI 10.1093/bja/88.6.864
-
Friederich P, Benzenberg D, Urban BW. Bupivacaine inhibits human neuronal Kv3 channels in SH-SY5Y human neuroblastoma cells. Br J Anaesth 2002;88(6):864-866 (Pubitemid 34618964)
-
(2002)
British Journal of Anaesthesia
, vol.88
, Issue.6
, pp. 864-866
-
-
Friederich, P.1
Benzenberg, D.2
Urban, B.W.3
-
128
-
-
0029096401
-
Regional anesthesia and local anesthetic-induced systemic toxicity: Seizure frequency and accompanying cardiovascular changes
-
Brown DL, Ransom DM, Hall JA, et al. Regional anesthesia and local anesthetic-induced systemic toxicity: seizure frequency and accompanying cardiovascular changes. Anesth Analg 1995;81(2):321-328
-
(1995)
Anesth Analg
, vol.81
, Issue.2
, pp. 321-328
-
-
Brown, D.L.1
Ransom, D.M.2
Hall, J.A.3
-
129
-
-
33745249950
-
v1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae
-
DOI 10.1124/mol.106.022970
-
Maertens C, Cuypers E, Amininasab M, et al. Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae. Mol Pharmacol 2006;70(1):405-414 (Pubitemid 43920830)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.1
, pp. 405-414
-
-
Maertens, C.1
Cuypers, E.2
Amininasab, M.3
Jalali, A.4
Vatanpour, H.5
Tytgat, J.6
-
130
-
-
33745228127
-
Subtype specificity of scorpion β-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3
-
DOI 10.1124/mol.106.024034
-
Leipold E, Hansel A, Borges A, Heinemann SH. Subtype specificity of scorpion beta-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3. Mol Pharmacol 2006;70(1):340-347 (Pubitemid 43920824)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.1
, pp. 340-347
-
-
Leipold, E.1
Hansel, A.2
Borges, A.3
Heinemann, S.H.4
-
131
-
-
55249117019
-
Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain II voltage sensor in the closed confi guration
-
Xiao Y, Bingham JP, Zhu W, et al. Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain II voltage sensor in the closed confi guration. J Biol Chem 2008;283(40):27300- 27313
-
(2008)
J Biol Chem
, vol.283
, Issue.40
, pp. 27300-27313
-
-
Xiao, Y.1
Bingham, J.P.2
Zhu, W.3
-
132
-
-
56949084009
-
JZTX-IV, a unique acidic sodium channel toxin isolated from the spider Chilobrachys jingzhao
-
doi:10.1016/j.toxicon.2008.08.018
-
Wang M, Diao J, Li J, et al. JZTX-IV, a unique acidic sodium channel toxin isolated from the spider Chilobrachys jingzhao. Toxicon 2008; doi:10.1016/j.toxicon.2008.08.018
-
(2008)
Toxicon
-
-
Wang, M.1
Diao, J.2
Li, J.3
-
133
-
-
34547798947
-
The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel
-
Rosker C, Lohberger B, Hofer D, et al. The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel. Am J Physiol Cell Physiol 2007;293(2):C783-9
-
(2007)
Am J Physiol Cell Physiol
, vol.293
, Issue.2
-
-
Rosker, C.1
Lohberger, B.2
Hofer, D.3
-
134
-
-
21144441514
-
Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain
-
DOI 10.1016/j.bmcl.2005.02.093, PII S0960894X05002660
-
Liang J, Brochu RM, Cohen CJ, et al. Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain. Bioorg Med Chem Lett 2005;15(11):2943-2947 (Pubitemid 40732252)
-
(2005)
Bioorganic and Medicinal Chemistry Letters
, vol.15
, Issue.11
, pp. 2943-2947
-
-
Liang, J.1
Brochu, R.M.2
Cohen, C.J.3
Dick, I.E.4
Felix, J.P.5
Fisher, M.H.6
Garcia, M.L.7
Kaczorowski, G.J.8
Lyons, K.A.9
Meinke, P.T.10
Priest, B.T.11
Schmalhofer, W.A.12
Smith, M.M.13
Tarpley, J.W.14
Williams, B.S.15
Martin, W.J.16
Parsons, W.H.17
-
135
-
-
37249070254
-
Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7
-
DOI 10.1021/bi7018207
-
Williams BS, Felix JP, Priest BT, et al. Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7. Biochemistry 2007;46(50):14693-14703 (Pubitemid 350276373)
-
(2007)
Biochemistry
, vol.46
, Issue.50
, pp. 14693-14703
-
-
Williams, B.S.1
Felix, J.P.2
Priest, B.T.3
Brochu, R.M.4
Dai, K.5
Hoyt, S.B.6
London, C.7
Tang, Y.S.8
Duffy, J.L.9
Parsons, W.H.10
Kaczorowski, G.J.11
Garcia, M.L.12
-
136
-
-
44649119304
-
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain
-
DOI 10.1016/j.bmc.2008.05.003, PII S0968089608004227
-
Drizin I, Gregg RJ, Scanio MJ, et al. Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain. Bioorg Med Chem 2008;16(12):6379-6386 (Pubitemid 351783416)
-
(2008)
Bioorganic and Medicinal Chemistry
, vol.16
, Issue.12
, pp. 6379-6386
-
-
Drizin, I.1
Gregg, R.J.2
Scanio, M.J.C.3
Shi, L.4
Gross, M.F.5
Atkinson, R.N.6
Thomas, J.B.7
Johnson, M.S.8
Carroll, W.A.9
Marron, B.E.10
Chapman, M.L.11
Liu, D.12
Krambis, M.J.13
Shieh, C.-C.14
Zhang, X.15
Hernandez, G.16
Gauvin, D.M.17
Mikusa, J.P.18
Zhu, C.Z.19
Joshi, S.20
Honore, P.21
Marsh, K.C.22
Roeloffs, R.23
Werness, S.24
Krafte, D.S.25
Jarvis, M.F.26
Faltynek, C.R.27
Kort, M.E.28
more..
-
137
-
-
39849107766
-
v1.7 channel blockers
-
DOI 10.1016/j.bmcl.2008.01.047, PII S0960894X08000620
-
London C, Hoyt SB, Parsons WH, et al. Imidazopyridines: a novel class of hNav1.7 channel blockers. Bioorg Med Chem Lett 2008;18(5):1696-1701 (Pubitemid 351318238)
-
(2008)
Bioorganic and Medicinal Chemistry Letters
, vol.18
, Issue.5
, pp. 1696-1701
-
-
London, C.1
Hoyt, S.B.2
Parsons, W.H.3
Williams, B.S.4
Warren, V.A.5
Tschirret-Guth, R.6
Smith, M.M.7
Priest, B.T.8
McGowan, E.9
Martin, W.J.10
Lyons, K.A.11
Li, X.12
Karanam, B.V.13
Jochnowitz, N.14
Garcia, M.L.15
Felix, J.P.16
Dean, B.17
Abbadie, C.18
Kaczorowski, G.J.19
Duffy, J.L.20
more..
-
138
-
-
39149092391
-
v1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain
-
DOI 10.1021/jm070637u
-
Kort ME, Drizin I, Gregg RJ, et al. Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain. J Med Chem 2008;51(3):407-416 (Pubitemid 351252269)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.3
, pp. 407-416
-
-
Kort, M.E.1
Drizin, I.2
Gregg, R.J.3
Scanio, M.J.C.4
Shi, L.5
Gross, M.F.6
Atkinson, R.N.7
Johnson, M.S.8
Pacofsky, G.J.9
Thomas, J.B.10
Carroll, W.A.11
Krambis, M.J.12
Liu, D.13
Shieh, C.-C.14
Zhang, X.15
Hernandez, G.16
Mikusa, J.P.17
Zhong, C.18
Joshi, S.19
Honore, P.20
Roeloffs, R.21
Marsh, K.C.22
Murray, B.P.23
Liu, J.24
Werness, S.25
Faltynek, C.R.26
Krafte, D.S.27
Jarvis, M.F.28
Chapman, M.L.29
Marron, B.E.30
more..
-
139
-
-
34347213786
-
v1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat
-
DOI 10.1073/pnas.0611364104
-
Jarvis MF, Honore P, Shieh CC, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci USA 2007;104(20):8520-8525 (Pubitemid 47175520)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.20
, pp. 8520-8525
-
-
Jarvis, M.F.1
Honore, P.2
Shieh, C.-C.3
Chapman, M.4
Joshi, S.5
Zhang, X.-F.6
Kort, M.7
Carroll, W.8
Marron, B.9
Atkinson, R.10
Thomas, J.11
Liu, D.12
Krambis, M.13
Liu, Y.14
McGaraughty, S.15
Chu, K.16
Roeloffs, R.17
Zhong, C.18
Mikusa, J.P.19
Hernandez, G.20
Gauvin, D.21
Wade, C.22
Zhu, C.23
Pai, M.24
Scanio, M.25
Shi, L.26
Drizin, I.27
Gregg, R.28
Matulenko, M.29
Hakeem, A.30
Gross, M.31
Johnson, M.32
Marsh, K.33
Wagoner, P.K.34
Sullivan, J.P.35
Faltynek, C.R.36
Krafte, D.S.37
more..
-
140
-
-
0031024171
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
DOI 10.1016/S0169-409X(96)00423-1, PII S0169409X96004231
-
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 1997;23:3-25 (Pubitemid 27046991)
-
(1997)
Advanced Drug Delivery Reviews
, vol.23
, Issue.1-3
, pp. 3-25
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
141
-
-
11144320699
-
Navigating chemical space for biology and medicine
-
DOI 10.1038/nature03193
-
Lipinski C, Hopkins A. Navigating chemical space for biology and medicine. Nature 2004;432(7019):855-861 (Pubitemid 40037141)
-
(2004)
Nature
, vol.432
, Issue.7019
, pp. 855-861
-
-
Lipinski, C.1
Hopkins, A.2
-
142
-
-
41549099967
-
The hERG K+ channel: Target and antitarget strategies in drug development
-
Raschi E, Vasina V, Poluzzi E, De Ponti F. The hERG K+ channel: target and antitarget strategies in drug development. Pharmacol Res 2008;57(3):181-195
-
(2008)
Pharmacol Res
, vol.57
, Issue.3
, pp. 181-195
-
-
Raschi, E.1
Vasina, V.2
Poluzzi, E.3
De Ponti, F.4
-
144
-
-
47549086709
-
hERG potassium channels and the structural basis of drug-induced arrhythmias
-
Mitcheson JS. hERG potassium channels and the structural basis of drug-induced arrhythmias. Chem Res Toxicol 2008;21(5):1005-1010
-
(2008)
Chem Res Toxicol
, vol.21
, Issue.5
, pp. 1005-1010
-
-
Mitcheson, J.S.1
-
145
-
-
0036258115
-
Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: An overview
-
De Ponti F, Poluzzi E, Cavalli A, et al. Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview. Drug Saf 2002;25(4):263-286 (Pubitemid 34569360)
-
(2002)
Drug Safety
, vol.25
, Issue.4
, pp. 263-286
-
-
De Ponti, F.1
Poluzzi, E.2
Cavalli, A.3
Recanatini, M.4
Montanaro, N.5
-
146
-
-
0036039326
-
The significance of QT interval in drug development
-
DOI 10.1046/j.1365-2125.2002.01627.x
-
Shah RR. The significance of QT interval in drug development. Br J Clin Pharmacol 2002;54(2):188-202 (Pubitemid 35024944)
-
(2002)
British Journal of Clinical Pharmacology
, vol.54
, Issue.2
, pp. 188-202
-
-
Shah, R.R.1
|