Distribution of voltage-gated sodium channel α-subunit and β-subunit mRNAs in human hippocampal formation, cortex, and cerebellum

Journal of Comparative Neurology

Volumn 422, Issue 1, 2000, Pages 123-139

  Whitaker, William R J ^a   Clare, Jeffrey J ^b   Powell, Andrew J ^b   Chen, Yu Hua ^b   Faull, Richard L M ^c   Emson, Piers C ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Human; In situ hybridisation; Ion channel; Northern blot; Oligonucleotide

Indexed keywords

MESSENGER RNA; OLIGONUCLEOTIDE; SODIUM CHANNEL;

ALPHA CHAIN; ARTICLE; BETA CHAIN; CENTRAL NERVOUS SYSTEM; ENTORHINAL CORTEX; GRANULE CELL; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN SITU HYBRIDIZATION; NORTHERN BLOTTING; PRIORITY JOURNAL; PURKINJE CELL;

ANIMALS; CEREBELLUM; CEREBRAL CORTEX; HIPPOCAMPUS; HUMANS; ION CHANNEL GATING; RATS; RNA, MESSENGER; SODIUM CHANNELS;

EID: 0034686371     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(20000619)422:1<123::AID-CNE8>3.0.CO;2-X     Document Type: Article

References (68)

1. Ahmed CMI, Ware DH, Lee SC, Patten CD, Ferrer-Montiel AV, Schinder AF, McPherson JD, Wagner-McPherson CB, Wasmuth JJ, Evans GA, Montal M. 1992. Primary structure, chromosomal localization, and functional expression of a voltage-gated sodium channel from human brain. Proc Natl Acad Sci USA 89:8220-8224.
2. + channel α-subunit with novel gating properties. Neuron 1:449-461.
3. Barchi RL, Cohen SA, Murphy LE. 1980. Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel. Proc Natl Acad Sci USA 77:1306-1310.
4. Barhanin J, Pauron D, Lombet A, Norman RI, Vijverberg HPM, Giglio JR, Lazdunski M. 1983. Electrophysiological characterization, solubilization and purification of the Tityus γ toxin receptor associated with the gating component of the Na+ channel from the rat brain. EMBO J 2:915-920.
5. Bartolomei F, Gastaldi M, Massacrier A, Planells R, Nicolas S, Gau P. 1997. Changes in the mRNAs encoding subtypes I, II and III sodium channel alpha subunits following kainate-induced seizures in rat brain. J Neurocytol 28:667-678.
6. Barton AJL, Pearson RCA, Najlerahim A, Harrison PJ. 1993. Pre- and post-mortem influences on brain RNA. J Neurochem 61:1-11.
7. Beckh S, Noda M, Lubbert H, Numa S. 1989. Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development. EMBO J 8:3611-3616.
8. Black JA, Waxman SG. 1996. Sodium channel expression: a dynamic process in neurons and non-neuronal cells. Dev Neurosci 18:139-152.
9. Black JA, Yokoyama S, Higashida H, Ransom BR, Waxman SG. 1994. Sodium channel mRNAs I, II and III in the CNS: cell-specific expression. Brain Res Mol Brain Res 22:275-289.
10. Bordey A, Sontheimer H. 1998. Properties of human glial cells associated with epileptic seizure foci. Epilepsy Res 32:286-303.
11. Brysch W, Creutzfeldt OD, Luno K, Schlingensiepen R, Schlingensiepen K-H. 1991. Regional and temporal expression of sodium channel messenger RNAs in rat brain during development. Exp Brain Res 86:562-567.
12. + channel in a mammalian cell line. J Physiol 513P:130P.
13. + channel from human brain. Ann NY Acad Sci 868:80-83.
14. D'Arcangelo G, Paradiso K, Shepherd D, Brehm P, Halegoua S, Mandel G. 1993. Neuronal growth factor regulation of two different sodium channel types through distinct signal transduction pathways. J Cell Biol 122:915-921.
15. + channels stably expressed in Chinese hamster ovary cells. J Physiol 513:129.
16. Dietrich PS, McGivern JG, Delgado SG, Koch BD, Eglen RM, Hunter JC, Sangameswaran L. 1998. Functional analysis of a voltage-gated sodium channel and its splice variant from rat dorsal root ganglia. J Neurochem 70:2262-2272.
17. Earl Patton D, Isom LL, Catterall WA, Goldin AL. 1994. The adult rat brain β1 subunit modifies activation and inactivation gating of multiple sodium channel α subunits. J Biol Chem 269(26):17649-17655.
18. Elmer LW, O'Brien, BJ, Nutter TJ, Angelides KJ. 1985. Physicochemical characterization of the α-peptide of the sodium channel from rat brain. Biochemistry 24:8128-8137.
19. Felts PA, Yokoyama S, Dib-Hajj S, Black JA, Waxman SG. 1997. Sodium channel α-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system. Brain Res Mol Brain Res 45:71-82.
20. + channel mRNA in the rat brain. Brain Res Mol Brain Res 17:169-173.
21. Gastaldi M, Bartolomei F, Massacrier A, Planells R, Robaglia-Schlupp A, Cau P. 1997. Increase in mRNAs encoding neonatal II and III sodium channel α-isoforms during kainate-induced seizures in adult rat hippocampus. Brain Res Mol Brain Res 44:179-190.
22. Gastaldi M, Robaglia-Schlupp A, Massacrier A, Planells R, Cau P. 1998. mRNA coding for voltage-gated sodium channel β2 subunit in rat central nervous system: cellular distribution and changes following kainate-induced seizures. Neurosci Lett 249:53-56.
23. Giraud P, Alcaraz G, Jullien F, Sampo B, Jover E, Couraud F, Dargent B. 1998. Multiple pathways regulate the expression of genes encoding sodium channel subunits in developing neurons. Brain Res Mol Brain Res 56:238-255.
24. II, sodium channel subtypes. Proc Natl Acad Sci USA 84:8682-8686.
25. Gustafson TA, Clevinger EC, O'Neill TJ, Yarowsky PJ, Krueger BK. 1993. Mutually exclusive exon splicing of the type III brain sodium channel α subunit generates developmentally regulated isoforms in rat brain. J Biol Chem 268:18648-18653.
26. Hartshorne RP, Catterall WA. 1984. The sodium channel from rat brain: purification and subunit composition. J Biol Chem 259:1667-1675.
27. Hille B. 1992. Ionic channels of excitable membranes, 2nd ed. Sunderland, MA: Sinauer Associates Inc.
28. Isom LL, De Jongh KS, Earl Patton D, Reber BFX, Offord J, Charbonneau, H, Walsh K, Goldin AL, Catterall WA. 1992. Primary structure and functional expression of the β1 subunit of the rat brain sodium channel. Science 256:839-842.
29. Isom LL, Scheuer T, Brownstein AB, Ragsdale DS, Murphy BJ, Catterall WA. 1995a. Functional co-expression of the β1 and IIA α subunits of sodium channels in a mammalian cell line. J Biol Chem 270:3306-3312.
30. Isom LL, Ragsdale DS, De Jongh KS, Westenbroek RE, Reber BFX, Scheuer T, Catterall WA. 1995b. Structure and function of the β2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif. Cell 83:433-442.
31. Kayano T, Noda M, Flockerzi V, Takahashi H, Numa S. 1988. Primary structure of rat brain sodium channel III deduced from the cDNA sequence. FEBS Lett 228:187-194.
32. Levy-Mozziconacci A, Alcaraz G, Giraud P, Boudier JA, Caillol G, Couraud F, Autillo-Touati A. 1998. Expression of the mRNA for the β2 subunit of the voltage-dependent sodium channel in the rat CNS. Eur J Neurosci 10:2757-2767.
33. Li M, West JW, Lai Y, Scheuer T, Catterall WA. 1992. Functional modulation of brain sodium channels by cAMP-dependent phosphorylation. Neuron 8:1151-1159.
34. Lombardo AJ, Kuzniecky R, Powers RE, Brown GB. 1996. Altered brain sodium channel transcript levels in human epilepsy. Brain Res Mol Brain Res 35:84-90.
35. Lu C-M, Brown GB. 1998. Isolation of a human-brain sodium-channel gene encoding two isoforms of the subtype III α-subunit. J Mol Neurol 10:67-70.
36. Lu C-M, Han J, Rado TA, Brown GB. 1992. Differential expression of two sodium channel subtypes in human brain. FEBS Lett 303:53-58.
37. Ma JY, Catterall WA, Scheuer T. 1997. Persistent sodium currents through brain sodium channels induced by G protein βγ subunits. Neuron 19:443-452.
38. + channels by nerve growth factor. Proc Natl Acad Sci USA 85:924-928.
39. McClatchey AI, Cannon, S. C., Slaugenhaupt, S.A. Gusella JF. 1993. The cloning and expression of a sodium channel β1-subunit cDNA from human brain. Hum Mol Genet 2(6):745-749.
40. Miller JA, Agnew WS, Levinson SR. 1983. Principal glycopeptide of the tetrodotoxin/saxitoxin binding protein from electrophorus electricus: isolation and partial chemical and physical characterization. Biochemistry 22:462-470.
41. Moorman JR, Kirsch GE, VanDongen AMJ, Joho RH, Brown AM. 1990. Fast and slow gating of sodium channels encoded by a single mRNA. Neuron 4:243-252.
42. Noda M, Ikeda T, Kayano T, Suzuki H, Takeshima H, Kurasaki M, Takahashi H, Numa S. 1986a. Existence of distinct sodium channel messenger RNAs in rat brain. Nature 320:188-192.
43. Noda M, Ikeda T, Suzuki H, Takeshima H, Takahashi T, Kuno M, Numa S. 1986b. Expression of functional sodium channels from cloned cDNA. Nature 322:826-828.
44. Numann R, Catterall WA, Scheuer T. 1991. Functional modulation of brain sodium channels by protein kinase C phosphorylation. Science 254: 115-118.
45. Oh Y, Waxman SG. 1998. Novel splice variants of the voltage-sensitive sodium channel alpha subunit. Neuroreport 9:1267-1272.
46. + channel β1 subunit mRNA in rat CNS neurons. Neurosci Lett 176:119-122.
47. Plummer NW, Galt J, Jones JM, Burgess DL, Sprunger LK, Kohrman DC, Meisler MH. 1998. Exon organization, coding sequence, physical mapping, and polymorphic intragenic markers for the human neuronal sodium channel gene SCN8A. Genomics 54:287-296.
48. + channel in Xenopus oocytes and mammalian cells [poster abstract]. J Physiol 513P:141P.
49. Sarao R, Gupta SK, Auld VJ, Dunn RJ. 1991. Developmentally regulated alternative RNA splicing of rat brain sodium channel mRNAs. Nucleic Acids Res 19:5673-5679.
50. Schaller KL, Krzemien DM, McKenna NM, Caldwell JH. 1992. Alternatively spliced sodium channel transcripts in brain and muscle. J Neurosci 12:1370-1381.
51. Schaller KL, Krzemien DM, Yarowsky PJ, Krueger BK, Caldwell JH. 1995. A novel, abundant sodium channel expressed in neurons and glia. J Neurosci 15:3231-3242.
52. Scheuer T, Auld VJ, Boyd S, Offord J, Dunn R, Catterall WA. 1990. Functional properties of rat brain sodium channels expressed in a somatic cell line. Science 247:854-858.
53. Smith MR, Smith RD, Plummer NW, Meisler MH, Goldin AL. 1998. Functional analysis of the mouse Scn8a sodium channel. J Neurosci 18(16): 6093-6102.
54. Smith RD, Goldin AL. 1998. Functional analysis of the rat I sodium channel in Xenopus oocytes. J Neurosci 18:811-820.
55. Sontheimer H, Waxman SG. 1993. Expression of voltage-activated ion channels by astrocytes and oligodendrocytes in the hippocampal slice. J Neurophysiol 70:1863-1873.
56. + channels in glia: properties and possible functions. Trends Neurosci 19:325-331.
57. Srinivasan J, Schachner M, Catterall WA. 1998. Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R. Proc Natl Acad Sci USA 95:15753-15757.
58. Suzuki H, Beckh S, Kubo H, Yahagi N, Ishida H, Kayano T, Noda M, Numa S. 1988. Functional expression of cloned cDNA encoding sodium channel III. FEBS Lett 228:195-200.
59. Vega-Saenz De Miera E, Rudy B, Sugimori M, Llinas R. 1997. Molecular characterization of the sodium channel subunits expressed in mammalian cerebellar Purkinje cells. Proc Natl Acad Sci USA 94:7059-7064.
60. Weber P, Bartsch U, Rasband MN, Czaniera R, Lang Y, Bluethmann H, Margolis RU, Rock Levinson S, Shrager P, Montag D, Schachner M. 1999. Mice deficient for tenascin-R display alterations of the extra cellular matrix and decreased axonal conduction velocities in the CNS. J Neurosci 19:4245-4265.
61. + channel α-subunits in a somatic cell line. Neuron 8:59-70.
62. + channel subtypes in central neurons. Neuron 3:695-704.
63. Whitaker WRJ, Clare JJ, Emson PC. 1999. Differential distribution of voltage-gated sodium channel α- and β-subunits in human brain. Ann NY Acad Sci 868:88-92.
64. Willow M, Taylor SM, Catterall WA, Finnell RH. 1986. Down regulation of sodium channels in nerve terminals of spontaneously epileptic mice. Cell Mol Neurobiol 6:213-220.
65. Xiao ZC, Ragsdale DS, Malhotra JD, Mattei LN, Braun PE, Schachner M, Isom LL. 1999. Tenascin-R is a functional modulator of sodium channel β subunits. J Biol Chem 274:26511-26517.
66. + channel α subunits stably expressed in a mammalian cell line. J Physiol 504:154.
67. Yarowsky PJ, Krueger BJ, Olson CE, Clevinger EC. 1991. Brain and heart channel subtype mRNA expression in rat cerebral cortex. Proc Natl Acad Sci USA 88:9453-9457.
68. Zur KB, Oh Y, Waxman SG, Black JA. 1995. Differential up-regulation of sodium channel α- and β-1 subunit mRNAs in cultured embryonic DRG neurons following exposure to NGF. Brain Res Mol Brain Res 30:97-105.