cAMP-dependent phosphorylation of the tetrodotoxin-resistant voltage-dependent sodium channel SNS

Journal of Physiology

Volumn 516, Issue 2, 1999, Pages 433-446

  Fitzgerald, E M ^a   Okuse, K ^a   Wood, J N ^a   Dolphin, A C ^a   Moss, S J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; ALANINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PROTEIN SUBUNIT; SERINE; SODIUM CHANNEL; TETRODOTOXIN; GLUTATHIONE TRANSFERASE VOLTAGE GATED SODIUM CHANNEL SNS FUSION PROTEIN; MUTANT PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL SNS;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CONTROLLED STUDY; ENZYME SUBSTRATE; HYPERALGESIA; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENSORY NERVE CELL; SITE DIRECTED MUTAGENESIS; AMINO ACID ANALYSIS; COS 7 CELL LINE; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; GENETIC TRANSFECTION; IN VITRO STUDY; MOLECULAR CLONING; PROTEIN PURIFICATION; RAT;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMALS; COS CELLS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG RESISTANCE; ELECTROPHYSIOLOGY; FORSKOLIN; GLUTATHIONE TRANSFERASE; ION CHANNEL GATING; MOLECULAR CONFORMATION; MUTAGENESIS, SITE-DIRECTED; PEPTIDE MAPPING; PHOSPHOPEPTIDES; PHOSPHORYLATION; RATS; SODIUM CHANNELS; TETRODOTOXIN; TRANSFECTION;

EID: 0033560866     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.0433v.x     Document Type: Article

References (49)

1. AKOPIAN, A. N., SIVILOTTI, L. & WOOD, J. N. (1096). A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons. Nature 379, 257-362.
2. ARBUCKLE, J. B. & DOCHERTY, R. J. (1985). Expression of tetrodotoxin-resistant sodium channels in capsaicin-sensitive dorsal root ganglion neurones of adult rats. Neuroscience Letters 185, 70-73.
3. CATTERALL, W. A. (1992). Cellular and molecular biology of voltagegated sodium channels. Physiological Reviews 72 (suppl.), S15-S41.
4. + channel inactivation by the β1 subunit: a deletion analysis. Pflügers Archiv 431, 186-195.
5. CHEN, T.-C., LAW, B., KONDRATYUK, T. & ROSSIE, S. (1995). Identification of soluble protein phosphatases that dephosphorylate voltage-sensitive sodium channels in rat brain. Journal of Biological Chemistry 270, 7750-7756.
6. COHEN, S. A. & LEVITT, L. K. (1993). Partial characterisation of the rH1 sodium channel protein from rat heart using subtype-specific antibodies. Circulation Research 73, 735-742.
7. COSTA, M. R. C., CASMELLIE, J. E. & CATTERALL, W. E. (1682). Selective phosphorylation of the a subunit of the sodium channel by cAMP-dependent protein kinase. Journal of Biological Chemistry 257, 7918-7921.
8. DEVOR, M., GOVRIN, L. R. & ANGELIDES, K. (1993). Journal of Neuroscience 13, 1976-1992.
9. DIB-HAJJ, S. D., TYRRELL, L., BLACK, J. A. & WAXMAN, S. G. (1998). NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy. Proceedings of the National Academy of Sciences of the USA 95, 8963-8968.
10. ELLIOTT, A. A. & ELLIOTT, J. R. (1993). Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia. Journal of Physiology 463, 39-56.
11. 2 modulates the tetrodotoxin-resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP-protein kinase A cascade. Journal of Physiology 495, 429-440.
12. ENGLAND, S., SOUSLOVA, V., AKOPIAN, A., OKUSE, K., OGATA, N. & WOOD, J. N. (1998). Voltage-gated sodium channels in sns null mutant mice. Society for Neuroscience Abstracts 24, 1821.
13. FROHNWIESER, B., CHEN, L-Q., SCHREIBMAYER, W. & KALLEN, R. G. (1997). Modulation of human cardiac channel α-subunit by cAMP-dependent protein kinase and the responsible sequence domain. Journal of Physiology 498, 309-318.
14. + channels in a mammalian cell line. Journal of Physiology 513.P, 141P.
15. + current in nociceptors. Proceedings of the National Academy of Sciences of the USA 93, 1108-1112.
16. HAMILL, O. P., MARTY, A., NEHER, E., SAKMANN, B. & SIGWORTH, F. J. (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Archiv 391, 85-100.
17. HILLE, B. (1992). Ionic Currents of Excitable Membranes, pp. 607. Sinauer Associates Inc., Sunderland, MA, USA.
18. ISOM, L. L., DE JONGH, K. S., PATTON, D. E., REBER, B. F., OFFORD, J., CHARBONNEAU, H., WALSH, K., GOLDIN, A. L. & CATTERALL, W. A. (1992). Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. Science 256, 839-842.
19. ISOM, L. L., RAGSDALE, D. S., DE JONGH, K. S., WESTBROEK, R. E., REBER, B. F. X., SCHEUER, T. & CATTERALL, W. A. (1995a). Structure and function of the β2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif. Cell 83, 433-442.
20. ISOM, L. L., SCHEUER, T., BROWNSTEIN, A. B., RAGSDALE, D. S., MURPHY, B. J. & CATTERALL, W. A. (19954). Functional coexpression of the β1 and Type IIA a subunits of sodium channels in a mammalian cell line. Journal of Biological Chemistry 270, 3306-3312.
21. KEMP, B. E. & PEARSON, R. B. (1990). Protein kinase recognition sequence motifs. Trends in Biochemical Sciences 15, 342-346.
22. KUNKEL, T. A. (1985). Rapid and efficient site-specific mutagenesis without phenotypic selection. Proceedings of the National Academy of Sciences of the USA 82, 488-492.
23. LI, M., WEST, J. W., LAI, Y., SCHEUER, T. & CATTERALL, W. A. (1992). Functional modulation of brain sodium channels by cAMP-dependent phosphorylation. Neuron 8, 1151-1159.
24. LI, M., WEST, J. W., NUMANN, R., MURPHY, B. J., SCHEUER, T. & CATTERALL, W. A. (1993). Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase. Science 261, 1439-1442.
25. MACFARLAND, R. T., ZELUS, B. D. & BEAVO, J. A. (1991). High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP-induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. Journal of Biological Chemistry 266, 136-142.
26. MOSS, S. J., DOCHERTY, C. A. & HUGANIR, R. L. (1992). Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor. Journal of Biological Chemistry 267, 14470-14476.
27. MURPHY, B. J., ROGERS, J., PERDICHIZZI, A. P., COLVIN, A. A. & CATTERALL, W. A. (1996). cAMP-dependent phosphorylation of two sites in the α subunit of the cardiac sodium channel. Journal of Biological Chemistry 271, 28837-28843.
28. +channel by cAMP-dependent protein kinase and phosphoprotein phosphatases. Journal of Biological Chemistry 268, 27355-27362.
29. + channels in rat dorsal root ganglia. Journal of Physiology 466, 9-37.
30. + channel beta 1 subunit mRNA in rat CNS neurons. Neuroscience Letters 176, 119-122.
31. 2-induced mechanical hyperalgesia in the rat. Neuroscience 64, 769-776.
32. PATTON, D. E., ISOM, L. L., CATTERALL, W. A. & GOLDIN, A. L. (1994). The adult rat brain β1 subunit modifies activation and inactivation gating of multiple sodium channel α subunits. Journal of Biological Chemistry 269, 17649-17655.
33. + channel expression in Xenopus oocytes by β1 subunits. Journal of Biological Chemistry 270, 25696-25701.
34. ROSSIE, S. & CATTERALL, W. A. (1989). Phosphorylation of the α subunit of rat brain sodium channels by cAMP-dependent protein kinase at a new site containing Ser686 and Ser687. Journal of Biological Chemistry 264, 14220-14224.
35. ROY, M. L. & NARAHASHI, T. (1992). Differential properties of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons. Journal of Neuroscience 12, 2104-2111.
36. RUSH, A. M., BRAU, M. E., ELLIOTT, A. A. & ELLIOTT, J. R. (1998). Electrophysiological properties of sodium current subtypes in small cells from adult rat dorsal root ganglia. Journal of Physiology 511, 771-789.
37. SANDBERG, M., BUTT, E., NOLTE, C, FISCHER, L., HALBRUGGE, M., BELTMAN, J., JAHNSEN, T., GENIESER, H. G., JASTOPF, B. & WALTER, U. (1991). Characterization of Sp-5,6-dichloro-1-β-D-ribofuranosyl-benzimidazole-3′,5′- monophosphorothioate (Sp-5,6-DCl-cBiMPS) as a potent and specific activator of cyclic-AMP-dependent protein kinase in cell extracts and intact cells. Biochemical Journal 279, 521-527.
38. SANGAMESWARAN, L., DELGADO, S. G., FISH, L. M., KOCH, B. D., JAKEMAN, L. B., STEWART, G. R., SZE, P., HUNTER, J. C., EGLEN, R. M. & HERMAN, R. C. (1996). Structure and function of a novel voltage-gated, tetrodotoxin-resistant sodium channel specific to sensory neurons. Journal of Biological Chemistry 271, 5953-5956.
39. + channel in rat dorsal root ganglion neurons and their blockade by halothane. European Journal of Neuroscience 10, 2547-2556.
40. SMITH, D. B. & JOHNSON K. S. (1988). Single step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67, 31-40.
41. SMITH, R. D. & GOLDIN, A. L. (1996). Phosphorylation of brain sodium channels in the I-II linker modulates channel function in Xenopus oocytes. Journal of Neuroscience 16, 1965-1974.
42. SMITH, R. D. & GOLDIN, A. L. (1997). Phosphorylation at a single site in the rat brain sodium channel is necessary and sufficient for current reduction by protein kinase A. Journal of Neuroscience 17, 6086-6093.
43. TAIWO, Y. O. & LEVINE, J. D. (1991). Further confirmation of the role of adenylyl cyclase and of cAMP-dependent protein kinase in primary afferent hyperalgesia. Neuroscience 44, 131-135.
44. 2+ current in cultured rat sensory neurones. Journal of Physiology 447, 391-407.
45. + channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties. Neuron 8, 663-676.
46. VILLIÈRE, V. & MCLACHLAN, E. M. (1996). Electrophysiological properties of neurons in intact rat dorsal root ganglia classified by conduction velocity and action potential duration. Journal of Neurophysiology 76, 1924-1941.
47. WAXMAN, S. G., KOCSIS, J. D. & BLACK, J. A. (1994). Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is re-expressed following axotomy. Journal of Neurophysiology 72, 466-470.
48. WOOLF, C. J., SAFIEH, G. B., MA, Q. P., CRILLY, P. & WINTER, J. (1994). Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 62, 327-331.
49. YUCKENBERG, P. D., WITNEY, F., GEISSELSODER, J. &MCCLARY, J. (1991). Site-directed in vitro mutagenesis using uracil-containing DNA and phagemid vectors. In Directed Mutagenesis: A Practical Approach, ed. McPHERSON, M. J., pp. 27-48. Oxford University Press, Oxford.