Mutation I136V alters electrophysiological properties of the NaV1.7 channel in a family with onset of erythromelalgia in the second decade

Molecular Pain

Volumn 4, Issue , 2008, Pages

  Cheng, Xiaoyang ^a,b   Dib Hajj, Sulayman D ^a,b   Tyrrell, Lynda ^a,b   Waxman, Stephen G ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL NAV1.7; ISOLEUCINE; SCN9A PROTEIN, HUMAN; SODIUM CHANNEL; VALINE;

ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; DISEASE COURSE; ELECTROPHYSIOLOGY; EMBRYO; ERYTHROMELALGIA; GENE MUTATION; HUMAN; HUMAN CELL; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL STIMULATION; NOCICEPTION; ONSET AGE; PATCH CLAMP; PATHOGENESIS; PRIORITY JOURNAL; SPINAL GANGLION; ADOLESCENT; ADULT; AMINO ACID SUBSTITUTION; CELL LINE; CHILD; GENETICS; KINETICS; PAIN; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADOLESCENT; ADULT; AGE OF ONSET; AMINO ACID SUBSTITUTION; CELL LINE; CHILD; ERYTHROMELALGIA; HUMANS; ISOLEUCINE; KINETICS; PAIN; PATCH-CLAMP TECHNIQUES; SODIUM CHANNELS; VALINE;

EID: 40449087926     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-4-1     Document Type: Article

References (39)