메뉴 건너뛰기




Volumn 16, Issue 5, 1998, Pages 301-313

Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors

Author keywords

Colony stimulating factor; Hematopoiesis; Receptor; Signal transduction

Indexed keywords

CYTOKINE RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 5; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL KINASE; PROTEIN TYROSINE KINASE;

EID: 0031667742     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.160301     Document Type: Review
Times cited : (157)

References (86)
  • 1
    • 0025285859 scopus 로고
    • Cytokines: Coordinators of immune and inflammatory responses
    • Arai KI, Lee F, Miyajima A et al. Cytokines: coordinators of immune and inflammatory responses. Annu Rev Biochem 1990;59:783-836.
    • (1990) Annu Rev Biochem , vol.59 , pp. 783-836
    • Arai, K.I.1    Lee, F.2    Miyajima, A.3
  • 2
    • 0003917246 scopus 로고
    • New York: Oxford University Press, Sambrook and Tooze Publications
    • Nicola NA. Guidebook to Cytokines and Their Receptors. New York: Oxford University Press, Sambrook and Tooze Publications, 1994:171-177.
    • (1994) Guidebook to Cytokines and Their Receptors , pp. 171-177
    • Nicola, N.A.1
  • 3
    • 0025740806 scopus 로고
    • Identification and characterization of a low-affinity granulocyte-macrophage colony-stimulating factor receptor on primary and cultured human melanoma cells
    • Baldwin GC, Golde DW, Widhopf GF et al. Identification and characterization of a low-affinity granulocyte-macrophage colony-stimulating factor receptor on primary and cultured human melanoma cells. Blood 1991;78:609-615.
    • (1991) Blood , vol.78 , pp. 609-615
    • Baldwin, G.C.1    Golde, D.W.2    Widhopf, G.F.3
  • 4
    • 0024549443 scopus 로고
    • Nonhaematopoietic tumor cells express functional GM-CSF receptors
    • Baldwin GC, Gasson JC, Kaufman SE et al. Nonhaematopoietic tumor cells express functional GM-CSF receptors. Blood 1989;73:1033-1037.
    • (1989) Blood , vol.73 , pp. 1033-1037
    • Baldwin, G.C.1    Gasson, J.C.2    Kaufman, S.E.3
  • 5
    • 0024846310 scopus 로고
    • Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor
    • Gearing DP, King JA, Gough NM et al. Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor. EMBO J 1989;8:3667-3676.
    • (1989) EMBO J , vol.8 , pp. 3667-3676
    • Gearing, D.P.1    King, J.A.2    Gough, N.M.3
  • 6
    • 0025770219 scopus 로고
    • A human high affinity interleukin-5 receptor (IL5r) is composed of an IL5-specific α chain and β chain shared with the receptor for GM-CSF
    • Tavemier J, Devos R, Comelic S et al. A human high affinity interleukin-5 receptor (IL5r) is composed of an IL5-specific α chain and β chain shared with the receptor for GM-CSF. Cell 1991;66:1175-1184.
    • (1991) Cell , vol.66 , pp. 1175-1184
    • Tavemier, J.1    Devos, R.2    Comelic, S.3
  • 7
    • 0025861759 scopus 로고
    • Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors
    • Kitamura T, Sato N, Arai K et al. Expression cloning of the human IL-3 receptor cDNA reveals a shared β subunit for the human IL-3 and GM-CSF receptors. Cell 1991;66:1165-1174.
    • (1991) Cell , vol.66 , pp. 1165-1174
    • Kitamura, T.1    Sato, N.2    Arai, K.3
  • 8
    • 0025637605 scopus 로고
    • Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): Reconstitution of a high-affinity GM-CSF receptor
    • Hayashida K, Kitamura T, Gorman DM et al. Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc Natl Acad Sci USA 1990;87:9655-9659.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9655-9659
    • Hayashida, K.1    Kitamura, T.2    Gorman, D.M.3
  • 9
    • 0028824907 scopus 로고
    • Hematopoietic and lung abnormalities in mice with a null mutation of the common β subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5
    • Robb L, Drinkwater CC, Metcalf D et al. Hematopoietic and lung abnormalities in mice with a null mutation of the common β subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5. Proc Natl Acad Sci USA 1995;92:9565-9569.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9565-9569
    • Robb, L.1    Drinkwater, C.C.2    Metcalf, D.3
  • 10
    • 0028945520 scopus 로고
    • High affinity chimeric human granulocyte-macrophage colony-stimulating factor receptor carrying the cytoplasmic domain of the beta subunit but not the alpha subunit transduces growth promoting signals in Ba/F3 cells
    • Muto A, Watanabe S, Miyajima A et al. High affinity chimeric human granulocyte-macrophage colony-stimulating factor receptor carrying the cytoplasmic domain of the beta subunit but not the alpha subunit transduces growth promoting signals in Ba/F3 cells. Biochem Biophys Res Commun 1995;208:368-375.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 368-375
    • Muto, A.1    Watanabe, S.2    Miyajima, A.3
  • 11
    • 0031036882 scopus 로고    scopus 로고
    • The structural and functional basis of cytokine receptor activation: Lessons from the common β subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3) and IL-5 receptors
    • Bagley CJ, Woodcock JM, Stomski FC et al. The structural and functional basis of cytokine receptor activation: lessons from the common β subunit of the granulocyte-macrophage colony-stimulating factor, interleukin-3 (IL-3) and IL-5 receptors. Blood 1997;89:1471-1482.
    • (1997) Blood , vol.89 , pp. 1471-1482
    • Bagley, C.J.1    Woodcock, J.M.2    Stomski, F.C.3
  • 12
    • 0026607168 scopus 로고
    • Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3)
    • Hara T, Miyajima A. Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3). EMBO J 1992;11:1875-1884.
    • (1992) EMBO J , vol.11 , pp. 1875-1884
    • Hara, T.1    Miyajima, A.2
  • 13
    • 0030637892 scopus 로고    scopus 로고
    • The structural basis of the biological actions of the GM-CSF receptor
    • Nicola NA, Smith A, Robb L et al. The structural basis of the biological actions of the GM-CSF receptor. Ciba Found Symp 1997;204:19-27.
    • (1997) Ciba Found Symp , vol.204 , pp. 19-27
    • Nicola, N.A.1    Smith, A.2    Robb, L.3
  • 14
    • 0025373264 scopus 로고
    • Low-affinity placenta-derived receptors for human granulocyte-macrophage colony-stimulating factor can deliver a proliferative signal to murine hemopoietic cells
    • Metcalf D, Nicola NA, Gearing DP et al. Low-affinity placenta-derived receptors for human granulocyte-macrophage colony-stimulating factor can deliver a proliferative signal to murine hemopoietic cells. Proc Natl Acad Sci USA 1990;87:4670-4674.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4670-4674
    • Metcalf, D.1    Nicola, N.A.2    Gearing, D.P.3
  • 15
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan JF. Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 1990;87:6934-6938.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6934-6938
    • Bazan, J.F.1
  • 16
    • 0028825499 scopus 로고
    • Molecular modeling of the GM-CSF and IL-3 receptor complexes
    • Lyne PD, Bamborough P, Duncan D et al. Molecular modeling of the GM-CSF and IL-3 receptor complexes. Protein Science 1995;4:2223-2233.
    • (1995) Protein Science , vol.4 , pp. 2223-2233
    • Lyne, P.D.1    Bamborough, P.2    Duncan, D.3
  • 17
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • De Vos AM, Ultsch M, Kossiakoff AA. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 1992;255:306-312.
    • (1992) Science , vol.255 , pp. 306-312
    • De Vos, A.M.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 18
    • 0029928504 scopus 로고    scopus 로고
    • Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor
    • Hilton DJ, Watowich SS, Katz L et al. Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor. J Biol Chem 1996;271:4699-4708.
    • (1996) J Biol Chem , vol.271 , pp. 4699-4708
    • Hilton, D.J.1    Watowich, S.S.2    Katz, L.3
  • 19
    • 0028052289 scopus 로고
    • The role of the WSXWS equivalent motif in growth hormone receptor function
    • Baumgartner JW, Wells CA, Chen CM et al. The role of the WSXWS equivalent motif in growth hormone receptor function. J Biol Chem 1994;269:29094-29101.
    • (1994) J Biol Chem , vol.269 , pp. 29094-29101
    • Baumgartner, J.W.1    Wells, C.A.2    Chen, C.M.3
  • 20
    • 0028233122 scopus 로고
    • Identification of residues in the first and fourth helices of human granulocyte-macrophage colony stimulating factor involved in binding to the α- and β- chains of the receptor
    • Hercus TR, Cambareri B, Dottore M et al. Identification of residues in the first and fourth helices of human granulocyte-macrophage colony stimulating factor involved in binding to the α- and β-chains of the receptor. Blood 1994;83:3500-3508.
    • (1994) Blood , vol.83 , pp. 3500-3508
    • Hercus, T.R.1    Cambareri, B.2    Dottore, M.3
  • 21
    • 0030960120 scopus 로고    scopus 로고
    • Crucial role of the residue Arg280 at the F′-G′ loop of the human GM-CSF receptor alpha chain for ligand recognition
    • Rajotte D, Cadieux C, Haman A et al. Crucial role of the residue Arg280 at the F′-G′ loop of the human GM-CSF receptor alpha chain for ligand recognition. J Exp Med 1997;185:1939-1950.
    • (1997) J Exp Med , vol.185 , pp. 1939-1950
    • Rajotte, D.1    Cadieux, C.2    Haman, A.3
  • 22
    • 0028245262 scopus 로고
    • 22, selectively interact with the α- and β-chains of its receptor and participate in function
    • 22, selectively interact with the α- and β-chains of its receptor and participate in function. J Biol Chem 1994;269:8488-8492.
    • (1994) J Biol Chem , vol.269 , pp. 8488-8492
    • Barry, S.C.1    Bagley, C.J.2    Phillips, J.3
  • 23
    • 0028226252 scopus 로고
    • Specific human granulocyte-macrophage colony-stimulating factor antagonists
    • Hercus TR, Bagley CJ, Cambareri B et al. Specific human granulocyte-macrophage colony-stimulating factor antagonists. Proc Natl Acad Sci USA 1994;91:5838-5842.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5838-5842
    • Hercus, T.R.1    Bagley, C.J.2    Cambareri, B.3
  • 24
    • 0029000927 scopus 로고
    • Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist
    • Tavernier J, Tuypens T, Verhee A et al. Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist. Proc Natl Acad Sci USA 1995;92:5194-5198.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5194-5198
    • Tavernier, J.1    Tuypens, T.2    Verhee, A.3
  • 26
    • 0028013295 scopus 로고
    • Histidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor
    • Lock P, Metcalf D, Nicola NA. Histidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor. Proc Natl Acad Sci USA 1994;91:252-256.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 252-256
    • Lock, P.1    Metcalf, D.2    Nicola, N.A.3
  • 27
    • 0029860206 scopus 로고    scopus 로고
    • A single tyrosine residue in the membrane proximal domain of the GM-CSF, IL-3 and IL-5 receptor common β chain is necessary and sufficient for high affinity binding and signaling by all three ligands
    • Woodcock JM, Bagley CJ, Zacharakis B et al. A single tyrosine residue in the membrane proximal domain of the GM-CSF, IL-3 and IL-5 receptor common β chain is necessary and sufficient for high affinity binding and signaling by all three ligands. J Biol Chem 1996;271:25999-26006.
    • (1996) J Biol Chem , vol.271 , pp. 25999-26006
    • Woodcock, J.M.1    Bagley, C.J.2    Zacharakis, B.3
  • 28
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin C-H. Dimerization of cell surface receptors in signal transduction. Cell 1995;80:213-223.
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.-H.1
  • 29
    • 0027205338 scopus 로고
    • Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3)
    • Sakamaki K, Wang HM, Miyajima I et al. Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3). J Biol Chem 1993;268:15833-15839.
    • (1993) J Biol Chem , vol.268 , pp. 15833-15839
    • Sakamaki, K.1    Wang, H.M.2    Miyajima, I.3
  • 30
    • 0029903629 scopus 로고    scopus 로고
    • A dominant negative granulocyte-macrophage colony-simulating factor receptor alpha chain reveals the multimeric structure of the receptor complex
    • Lia F, Rajotte D, Clark SC et al. A dominant negative granulocyte-macrophage colony-simulating factor receptor alpha chain reveals the multimeric structure of the receptor complex. J Biol Chem 1996;271:28287-28293.
    • (1996) J Biol Chem , vol.271 , pp. 28287-28293
    • Lia, F.1    Rajotte, D.2    Clark, S.C.3
  • 31
    • 0029804197 scopus 로고    scopus 로고
    • Functional replacement of cytokine receptor extracellular domains by leucine zippers
    • Patel N, Herrman JM, Timans JC et al. Functional replacement of cytokine receptor extracellular domains by leucine zippers. J Biol Chem 1996;271:30386-30391.
    • (1996) J Biol Chem , vol.271 , pp. 30386-30391
    • Patel, N.1    Herrman, J.M.2    Timans, J.C.3
  • 32
    • 0027328343 scopus 로고
    • The alphas, betas, and kinases of cytokine complexes
    • Stahl N, Yancopolous GD. The alphas, betas, and kinases of cytokine complexes. Cell 1993;74:587-590.
    • (1993) Cell , vol.74 , pp. 587-590
    • Stahl, N.1    Yancopolous, G.D.2
  • 33
    • 0031974879 scopus 로고    scopus 로고
    • Identification of a Cys Motif in the Common β chain of the IL-3, GM-CSF and IL-5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors
    • Stomski FC, Woodcock JM, Zacharakis B et al. Identification of a Cys Motif in the Common β chain of the IL-3, GM-CSF and IL-5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors. J Biol Chem 1998;273:1192-1199.
    • (1998) J Biol Chem , vol.273 , pp. 1192-1199
    • Stomski, F.C.1    Woodcock, J.M.2    Zacharakis, B.3
  • 34
    • 0028147363 scopus 로고
    • Identification of conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit critical for function. Evidence for formation of a heterodimeric receptor complex prior to ligand binding
    • Ronco LV, Silverman SL, Wong SG et al. Identification of conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit critical for function. Evidence for formation of a heterodimeric receptor complex prior to ligand binding. J Biol Chem 1994;269:277-283.
    • (1994) J Biol Chem , vol.269 , pp. 277-283
    • Ronco, L.V.1    Silverman, S.L.2    Wong, S.G.3
  • 35
    • 0030744972 scopus 로고    scopus 로고
    • The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exists as a preformed receptor complex that can be activated by GM-CSF interleukin-3, or interleukin-5
    • Woodcock JM, McClure B, Stomski FC et al. The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exists as a preformed receptor complex that can be activated by GM-CSF interleukin-3, or interleukin-5. Blood 1997;90:3005-3017.
    • (1997) Blood , vol.90 , pp. 3005-3017
    • Woodcock, J.M.1    McClure, B.2    Stomski, F.C.3
  • 36
    • 0031010495 scopus 로고    scopus 로고
    • Secondary dimerization between members of the epidermal growth factor receptor family
    • Gamett DC, Pearson G, Cerione RA et al. Secondary dimerization between members of the epidermal growth factor receptor family. J Biol Chem 1997;272:12052-12056.
    • (1997) J Biol Chem , vol.272 , pp. 12052-12056
    • Gamett, D.C.1    Pearson, G.2    Cerione, R.A.3
  • 37
    • 0028302018 scopus 로고
    • ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
    • Soltoff SP, Carraway KL, Prigent SA et al. ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol Cell Biol 1994;14:3550-3558.
    • (1994) Mol Cell Biol , vol.14 , pp. 3550-3558
    • Soltoff, S.P.1    Carraway, K.L.2    Prigent, S.A.3
  • 38
    • 0027493844 scopus 로고
    • Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptors
    • Pan CX, Fukunaga R, Yonehara S et al. Unidirectional cross-phosphorylation between the granulocyte colony-stimulating factor and interleukin 3 receptors. J Biol Chem 1993;268:25818-25823.
    • (1993) J Biol Chem , vol.268 , pp. 25818-25823
    • Pan, C.X.1    Fukunaga, R.2    Yonehara, S.3
  • 39
    • 0028301446 scopus 로고
    • Steel factor stimulates the serine/threonine phosphorylation of the interleukin-3 receptor
    • Liu L, Cutler RL, Mui ALF et al. Steel factor stimulates the serine/threonine phosphorylation of the interleukin-3 receptor. J Biol Chem 1994;269:16774-16779.
    • (1994) J Biol Chem , vol.269 , pp. 16774-16779
    • Liu, L.1    Cutler, R.L.2    Mui, A.L.F.3
  • 40
    • 0028937977 scopus 로고
    • Erythropoietin induces tyrosine phosphorylation of the beta chain of the GM-CSF receptor
    • Hanazono Y, Sasaki K, Nitta H et al. Erythropoietin induces tyrosine phosphorylation of the beta chain of the GM-CSF receptor. Biochem Biophys Res Commun 1995;208:1060-1066.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 1060-1066
    • Hanazono, Y.1    Sasaki, K.2    Nitta, H.3
  • 41
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995;80:179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 42
    • 0028068607 scopus 로고
    • Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase
    • Welham MJ, Dechert U, Leslie KB et al. Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3′-kinase. J Biol Chem 1994;269:23764-23768.
    • (1994) J Biol Chem , vol.269 , pp. 23764-23768
    • Welham, M.J.1    Dechert, U.2    Leslie, K.B.3
  • 43
    • 0031469093 scopus 로고    scopus 로고
    • c chain of the granulocyte-macrophage colony-stimulating factor receptor
    • c chain of the granulocyte-macrophage colony-stimulating factor receptor. Blood 1997;90:4759-4766.
    • (1997) Blood , vol.90 , pp. 4759-4766
    • Okuda, K.1    Smith, L.2    Griffin, J.D.3
  • 44
    • 0031012544 scopus 로고    scopus 로고
    • Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells
    • Welham MJ, Bone H, Levings M et al. Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells. J Biol Chem 1997;272:1377-1381.
    • (1997) J Biol Chem , vol.272 , pp. 1377-1381
    • Welham, M.J.1    Bone, H.2    Levings, M.3
  • 45
    • 0028932614 scopus 로고
    • The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells
    • Odai H, Sasaki K, Iwamatsu A et al. The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells. J Biol Chem 1995;270:10800-10805.
    • (1995) J Biol Chem , vol.270 , pp. 10800-10805
    • Odai, H.1    Sasaki, K.2    Iwamatsu, A.3
  • 46
    • 0030043033 scopus 로고    scopus 로고
    • Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells
    • Hanazono Y, Odai H, Sasaki K et al. Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells. Acta Haematol 1996;95:236-242.
    • (1996) Acta Haematol , vol.95 , pp. 236-242
    • Hanazono, Y.1    Odai, H.2    Sasaki, K.3
  • 47
    • 0029056076 scopus 로고
    • Identification of a viability domain in the granulocyte/macrophage colony-stimulating factor receptor beta-chain involving tyrosine-750
    • Inhorn RC, Carlesso N, Durstin M et al. Identification of a viability domain in the granulocyte/macrophage colony-stimulating factor receptor beta-chain involving tyrosine-750. Proc Natl Acad Sci USA 1995;92:8665-8669.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8665-8669
    • Inhorn, R.C.1    Carlesso, N.2    Durstin, M.3
  • 48
    • 0027494821 scopus 로고
    • Signal transduction by the high affinity GM-CSF receptor: Two distinct cytoplasmic regions of the common β subunit responsible for different signaling
    • Sato N, Sakamaki K, Terada N et al. Signal transduction by the high affinity GM-CSF receptor: two distinct cytoplasmic regions of the common β subunit responsible for different signaling. EMBO J 1993;12:4181-4189.
    • (1993) EMBO J , vol.12 , pp. 4181-4189
    • Sato, N.1    Sakamaki, K.2    Terada, N.3
  • 49
    • 0028985012 scopus 로고
    • Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL
    • Matsuguchi T, Inhorn RC, Carlesso N et al. Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM-CSF, IL-3 and steel factor and is constitutively increased by p210BCR/ABL. EMBO J 1995;14:257-265.
    • (1995) EMBO J , vol.14 , pp. 257-265
    • Matsuguchi, T.1    Inhorn, R.C.2    Carlesso, N.3
  • 50
    • 0031931409 scopus 로고    scopus 로고
    • Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor
    • Itoh T, Liu R, Yokota T et al. Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor. Mol Cell Biol 1998;18:742-752.
    • (1998) Mol Cell Biol , vol.18 , pp. 742-752
    • Itoh, T.1    Liu, R.2    Yokota, T.3
  • 51
    • 0031000904 scopus 로고    scopus 로고
    • Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl
    • Odai H, Sasaki K, Iwamatsu A et al. Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr-Abl. Blood 1997;89:2745-2756.
    • (1997) Blood , vol.89 , pp. 2745-2756
    • Odai, H.1    Sasaki, K.2    Iwamatsu, A.3
  • 52
    • 0028963550 scopus 로고
    • Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STATS homologs
    • Mui AL-F, Wakao H, O'Farrell A-M et al. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STATS homologs. EMBO J 1995;14:1166-1175.
    • (1995) EMBO J , vol.14 , pp. 1166-1175
    • Mui, A.L.-F.1    Wakao, H.2    O'Farrell, A.-M.3
  • 53
    • 0028180569 scopus 로고
    • c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane proximal region
    • c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane proximal region. Mol Cell Biol 1994;14:4335-4341.
    • (1994) Mol Cell Biol , vol.14 , pp. 4335-4341
    • Quelle, F.W.1    Sato, N.2    Witthuhn, B.A.3
  • 54
    • 0032473935 scopus 로고    scopus 로고
    • Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation
    • Chaturvedi P, Reddy MV, Reddy EP. Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation. Oncogene 1998;16:1749-1758.
    • (1998) Oncogene , vol.16 , pp. 1749-1758
    • Chaturvedi, P.1    Reddy, M.V.2    Reddy, E.P.3
  • 55
    • 0031457622 scopus 로고    scopus 로고
    • Signaling through scaffold, anchoring, and adaptor proteins
    • Pawson T, Scott JD. Signaling through scaffold, anchoring, and adaptor proteins. Science 1997;278:2075-2080.
    • (1997) Science , vol.278 , pp. 2075-2080
    • Pawson, T.1    Scott, J.D.2
  • 56
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell Jr. JE, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994;264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 57
    • 0029892399 scopus 로고    scopus 로고
    • Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: Role of Stat5 in proliferation
    • Mui AL, Wakao H, Kinoshita T et al. Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation. EMBO J 1996;15:2425-2433.
    • (1996) EMBO J , vol.15 , pp. 2425-2433
    • Mui, A.L.1    Wakao, H.2    Kinoshita, T.3
  • 58
    • 0029014206 scopus 로고
    • A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
    • Yoshimura A, Ohkubo T, Kiguchi T et al. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J 1995;14:2816-2826.
    • (1995) EMBO J , vol.14 , pp. 2816-2826
    • Yoshimura, A.1    Ohkubo, T.2    Kiguchi, T.3
  • 59
    • 0030839112 scopus 로고    scopus 로고
    • A new protein containing an SH2 domain that inhibits JAK kinases
    • Endo TA, Masuhara M, Yokouchi M et al. A new protein containing an SH2 domain that inhibits JAK kinases. Nature 1997;387:921-924.
    • (1997) Nature , vol.387 , pp. 921-924
    • Endo, T.A.1    Masuhara, M.2    Yokouchi, M.3
  • 60
    • 0030792590 scopus 로고    scopus 로고
    • A family of cytokine inducible inhibitors of signaling
    • Starr R, Willson T, Viney E et al. A family of cytokine inducible inhibitors of signaling. Nature 1997;387:917-921.
    • (1997) Nature , vol.387 , pp. 917-921
    • Starr, R.1    Willson, T.2    Viney, E.3
  • 61
    • 0029887634 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling
    • Itoh T, Muto A, Watanabe S et al. Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling. J Biol Chem 1996;271:7587-7592.
    • (1996) J Biol Chem , vol.271 , pp. 7587-7592
    • Itoh, T.1    Muto, A.2    Watanabe, S.3
  • 62
    • 0029939507 scopus 로고    scopus 로고
    • c of the granulocyte macrophage colony-stimulating factor
    • c of the granulocyte macrophage colony-stimulating factor. J Biol Chem 1996;271:12137-12140.
    • (1996) J Biol Chem , vol.271 , pp. 12137-12140
    • Pratt, J.C.1    Weiss, M.2    Sieff, C.A.3
  • 63
    • 0028968362 scopus 로고
    • Overexpression of Shc proteins potentiates the proliferative response to granulocyte-macrophage colony-stimulating factor and recruitment of Grb/SoS and Grb2/p140 complexes to the beta receptor subunit
    • Lanfrancone L, Pelicci G, Brizzi M et al. Overexpression of Shc proteins potentiates the proliferative response to granulocyte-macrophage colony-stimulating factor and recruitment of Grb/SoS and Grb2/p140 complexes to the beta receptor subunit. Oncogene 1995;10:907-917.
    • (1995) Oncogene , vol.10 , pp. 907-917
    • Lanfrancone, L.1    Pelicci, G.2    Brizzi, M.3
  • 65
    • 0028068607 scopus 로고
    • Il-3 and GM-CSF, but not IL-4, induce tyrosine phosphorylation, activation and association of SHPTP2 with Grb2 and PI3-kinase
    • Welham MJ, Dechert U, Leslies KB et al. Il-3 and GM-CSF, but not IL-4, induce tyrosine phosphorylation, activation and association of SHPTP2 with Grb2 and PI3-kinase. J Biol Chem 1994;269:23764-23768.
    • (1994) J Biol Chem , vol.269 , pp. 23764-23768
    • Welham, M.J.1    Dechert, U.2    Leslies, K.B.3
  • 66
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR, Cantley LC. PI3K: Downstream AKTion blocks apoptosis. Cell 1997;88:435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 67
    • 0026733625 scopus 로고
    • Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation
    • Sakamaki K, Miyajima I, Kitamura T et al. Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation. EMBO J 1992;11:3541-3549.
    • (1992) EMBO J , vol.11 , pp. 3541-3549
    • Sakamaki, K.1    Miyajima, I.2    Kitamura, T.3
  • 68
    • 15844389026 scopus 로고    scopus 로고
    • JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in Ba/F3 cells
    • Watanabe S, Itoh T, Arai K. JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in Ba/F3 cells. J Biol Chem 1996;271:12681-12686.
    • (1996) J Biol Chem , vol.271 , pp. 12681-12686
    • Watanabe, S.1    Itoh, T.2    Arai, K.3
  • 69
    • 0030308963 scopus 로고    scopus 로고
    • The functions of Myc in cell cycle progression and apoptosis
    • Steiner P, Rudolph B, Muller D et al. The functions of Myc in cell cycle progression and apoptosis. Prog Cell Cycle Res 1996;2:73-82.
    • (1996) Prog Cell Cycle Res , vol.2 , pp. 73-82
    • Steiner, P.1    Rudolph, B.2    Muller, D.3
  • 70
    • 0031032525 scopus 로고    scopus 로고
    • Cytoplasmic domains of the common β-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines
    • Smith A, Metcalf D, Nicola NA. Cytoplasmic domains of the common β-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines. EMBO J 1997;16:451-464.
    • (1997) EMBO J , vol.16 , pp. 451-464
    • Smith, A.1    Metcalf, D.2    Nicola, N.A.3
  • 71
    • 0028837491 scopus 로고
    • Suppression of apoptotic death in hematopoietic cells by signaling through the IL-3/GM-CSF receptors
    • Kinoshita T, Yokota T, Arai K et al. Suppression of apoptotic death in hematopoietic cells by signaling through the IL-3/GM-CSF receptors. EMBO J 1995;14:266-275.
    • (1995) EMBO J , vol.14 , pp. 266-275
    • Kinoshita, T.1    Yokota, T.2    Arai, K.3
  • 72
    • 0029902217 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Shc is not required for proliferation or viability signaling by granulocyte-macrophage colony-stimulating factor in hematopoietic cell lines
    • Durstin M, Inhorn RC, Griffin JD. Tyrosine phosphorylation of Shc is not required for proliferation or viability signaling by granulocyte-macrophage colony-stimulating factor in hematopoietic cell lines. J Immunol 1996;157:534-540.
    • (1996) J Immunol , vol.157 , pp. 534-540
    • Durstin, M.1    Inhorn, R.C.2    Griffin, J.D.3
  • 73
    • 0031053586 scopus 로고    scopus 로고
    • Regulation of neuronal survival by the serine-threonine protein kinase Akt
    • Dudek H, Datta SR, Franke TF et al. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 1997;275:661-665.
    • (1997) Science , vol.275 , pp. 661-665
    • Dudek, H.1    Datta, S.R.2    Franke, T.F.3
  • 74
    • 0031039024 scopus 로고    scopus 로고
    • Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
    • Franke TF, Kaplan DR, Cantley LC et al. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 1997;275:665-668.
    • (1997) Science , vol.275 , pp. 665-668
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 75
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of Bad through the protein kinase Akt
    • del Peso L, Gonzalez-Garcia M, Page C et al. Interleukin-3-induced phosphorylation of Bad through the protein kinase Akt. Science 1997;278:687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3
  • 76
    • 0031470652 scopus 로고    scopus 로고
    • The structural basis for 14-3-3:phosphopeptide binding specificity
    • Yaffe MB, Rittinger K, Volinia S et al. The structural basis for 14-3-3:phosphopeptide binding specificity. Cell 1997;91:961-971.
    • (1997) Cell , vol.91 , pp. 961-971
    • Yaffe, M.B.1    Rittinger, K.2    Volinia, S.3
  • 78
    • 0031903015 scopus 로고    scopus 로고
    • Downstream signaling events regulated by phosphatidylinositol 3-kinase activity
    • Duronio V, Scheid MP, Ettinger S. Downstream signaling events regulated by phosphatidylinositol 3-kinase activity. Cell Signal 1998;10:233-239.
    • (1998) Cell Signal , vol.10 , pp. 233-239
    • Duronio, V.1    Scheid, M.P.2    Ettinger, S.3
  • 79
    • 0030860493 scopus 로고    scopus 로고
    • The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation
    • Damen JE, Liu L, Wakao H et al. The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation. Leukemia 1997;11:423-425.
    • (1997) Leukemia , vol.11 , pp. 423-425
    • Damen, J.E.1    Liu, L.2    Wakao, H.3
  • 80
    • 0344655326 scopus 로고    scopus 로고
    • Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions
    • Nishinakamura R, Miyajima A, Mee PJ et al. Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions. Blood 1996;88:2458-2464.
    • (1996) Blood , vol.88 , pp. 2458-2464
    • Nishinakamura, R.1    Miyajima, A.2    Mee, P.J.3
  • 81
    • 0028263504 scopus 로고
    • Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
    • Dranoff G, Crawford AD, Sadelain M et al. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 1994;264:713-716.
    • (1994) Science , vol.264 , pp. 713-716
    • Dranoff, G.1    Crawford, A.D.2    Sadelain, M.3
  • 82
    • 0028236526 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology
    • Stanley E, Lieschke GJ, Grail D et al. Granulocyte-macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc Natl Acad Sci USA 1994;91:5592-5596.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5592-5596
    • Stanley, E.1    Lieschke, G.J.2    Grail, D.3
  • 83
    • 0030711559 scopus 로고    scopus 로고
    • Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression
    • Dirksen U, Nishinakamura R, Groneck P et al. Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression. J Clin Invest 1997;100:2211-2217.
    • (1997) J Clin Invest , vol.100 , pp. 2211-2217
    • Dirksen, U.1    Nishinakamura, R.2    Groneck, P.3
  • 84
    • 0030038425 scopus 로고    scopus 로고
    • Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF deficient mice
    • Huffman JA, Hull WM, Dranoff G et al. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF deficient mice. J Clin Invest 1996;97:649-655.
    • (1996) J Clin Invest , vol.97 , pp. 649-655
    • Huffman, J.A.1    Hull, W.M.2    Dranoff, G.3
  • 85
    • 0031987330 scopus 로고    scopus 로고
    • Essential roles for granulocyte-macrophage colony-stimulating factor (GM-CSF) and G-CSF in the sustained hematopoietic response of listeria monocytogenes-infected mice
    • Zhan Y, Lieschke GJ, Grail D et al. Essential roles for granulocyte-macrophage colony-stimulating factor (GM-CSF) and G-CSF in the sustained hematopoietic response of listeria monocytogenes-infected mice. Blood 1998;91:863-869.
    • (1998) Blood , vol.91 , pp. 863-869
    • Zhan, Y.1    Lieschke, G.J.2    Grail, D.3
  • 86
    • 0030838839 scopus 로고    scopus 로고
    • Mice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-term survival
    • Seymour JF, Lieschke GJ, Grail D et al. Mice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-term survival. Blood 1997;90:3037-3049.
    • (1997) Blood , vol.90 , pp. 3037-3049
    • Seymour, J.F.1    Lieschke, G.J.2    Grail, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.