C/EBPβ and GATA-1 synergistically regulate activity of the eosinophil granule major basic protein promoter: Implication for C/EBPβ activity in eosinophil gene expression

Blood

Volumn 94, Issue 4, 1999, Pages 1429-1439

  Yamaguchi, Yuji ^a   Nishio, Hitoshi ^b   Kishi, Kenji ^b   Ackerman, Steven J ^b   Suda, Toshio ^b  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; MAJOR BASIC PROTEIN; CCAAT ENHANCER BINDING PROTEIN; DNA BINDING PROTEIN; EOSINOPHIL GRANULE PROTEIN; ERYTHROID SPECIFIC DNA BINDING FACTOR; GATA1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PLASMA PROTEIN; RIBONUCLEASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1;

ARTICLE; BINDING SITE; ENHANCER REGION; EOSINOPHIL; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; CELL STRAIN HL 60; GENE EXPRESSION REGULATION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

BASE SEQUENCE; BLOOD PROTEINS; CCAAT-ENHANCER-BINDING PROTEINS; DNA-BINDING PROTEINS; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HL-60 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); RIBONUCLEASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 0033566366     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.4.1429.416k13_1429_1439     Document Type: Article

References (74)

1. Clutterbuck EJ, Hirst EM, Sanderson CJ: Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6, and GMCSF. Blood 73:1504, 1989
2. Silberstein DS, David JR: The regulation of human eosinophil function by cytokines. Immunol Today 8:380, 1987
3. Yamaguchi Y, Suda T, Suda J, Eguchi M, Miura Y, Harada N, Tominaga A, Takatsu K: Purified interleukin 5 suppoprts the terminal differentiation and proliferation of murine eosinophilic precursors. J Exp Med 167:43, 1988
4. Yamaguchi Y, Matsui T, Kasahara T, Etoh S, Tominaga A, Takatsu K, Miura Y, Suda T: In vivo changes of hemopoietic progenitors and the expression of the interleukin 5 gene in eosinophilic mice infected with Toxocara canis. Exp Hematol 18:1152, 1990
5. Yamaguchi Y, Suda T, Shiozaki Y, Miura Y, Hitoshi Y, Tominaga A, Takatsu K, Kasahara T: Role of IL-5 in IL-2-induced eosinophilia. In vivo and in vitro expression of IL-5 mRNA by IL-2. J Immunol 145:873, 1990
6. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4:15, 1996
7. Yamaguchi Y, Zhang D-E, Sun Z, Albee EA, Nagata S, Tenen DG, Ackerman SJ: Functional characterization of the promoter for the gene encoding human eosinophil peroxidase. J Biol Chem 269:19410, 1994
8. Gomolin HI, Yamaguchi Y, Paulpillai AV, Dvorak LA, Ackerman SJ, Tenen DG: Human eosinophil Charcot-Leyden crystal protein: Cloning and characterization of a lysophospholipase gene promoter. Blood 82:1868, 1993
9. Yamaguchi Y, Ackerman SJ, Minegishi N, Takiguchi M, Yamamoto M, Suda T: Mechanisms of transcription in eosinophils: GATA-1, but not GATA-2, transactivates the promoter of the eosinophil granule major basic protein gene. Blood 91:3447, 1998
10. Landschulz WH, Johnson PF, Adashi EY, Graves BJ, McKnight SL: Isolation of a recombinant copy of the gene encoding C/EBP. Genes Dev 2:786, 1988
11. Xanthopoulos KG, Mirkovitch J, Decker T, Kuo CF, Darnell JE Jr: Cell-specific transcriptional control of the mouse DNA-binding protein mC/EBP. Proc Natl Acad Sci USA 86:4117, 1989
12. Akira S, Isshiki H, Sugita T, Tanabe O, Kinoshita S, Nishio Y, Nakajima T, Hirano T, Kishimoto T: A nuclear factor for IL-6 expression is a member of a C/EBP family. EMBO J 9:1897, 1990
13. Chang CJ, Chen TT, Lei HY, Chen DS, Lee SC: Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family. Mol Cell Biol 10:6642, 1990
14. Descombes P, Chojkier M, Lichtsteiner S, Falvey E, Schibler U: LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein. Genes Dev 4:1541, 1990
15. Poli V, Mancini FP, Cortese R: IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Cell 63:643, 1990
16. Roman C, Platero JS, Shuman JD, Calame K: Ig/EBP-1: A ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP. Genes Dev 4:1404, 1990
17. Cao Z, Umek RM, McKnight SL: Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev 5:1538, 1991
18. Kageyama R, Sasai Y, Nakanishi S: Molecular characterization of transcription factors that bind to the cAMP responsive region of the substance P precursor gene. J Biol Chem 266:15525, 1991
19. Williams SC, Cantwell CA, Johnson PA: A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev 5:1553, 1991
20. Kinoshita S, Akira S, Kishimoto T: A member of the C/EBP family, NF-IL6β, forms a heterodimer and transcriptionally synergizes with NF-IL6. Proc Natl Acad Sci USA 87:1473, 1992
21. Antonson P, Stellan B, Yamanaka R, Xanthopoulos KG: A novel human CCAAT/enhancer binding protein gene, C/EBP∈, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 clone to the T-cell receptor α/δ locus. Genomics 35:30, 1996
22. Chumakov AM, Grillier I, Chumakova E, Chih D, Slater J, Koeffler HP: Cloning of the novel human myeloid-specific C/EBP transcription factor (C/EBP∈). Mol Cell Biol 17:1375, 1997
23. Ron D, Habener JF: Chop, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev 6:439, 1992
24. van Ooji C, Snyder RC, Paeper BW, Duester G: Temporal expression of the human alcohol dehydrogenase gene family during liver development correlates with differential promoter activation by hepatocyte nuclear factor 1, CCAAT/enhancer-binding protein. Mol Cell Biol 12:3023, 1992
25. Nishiyori A, Tashiro H, Kimura A, Akagi K, Yamamura K, Mori M, Takiguchi M: Determination of tissue specificity of the enhancer by combinatorial operation of tissue-enriched transcription factors: Both HNF-4 and C/EBPβ are required for liver-specific activity of the omithine transcarbamylase enhancer. J Biol Chem 269:1323, 1994
26. Manchado C, Yubero P, Vinas O, Iglesias R, Villavroya F, Mampel T, Giralt M: CCAAT/binding proteins α and β in human adipose tissue: Evidence for a tissue-specific pattern of expression during development. Biochem J 302:695, 1994
27. Tanaka T, Yoshida N, Kishimoto T, Akira S: Defective adipocyte differentiation in mice lacking the C/EBPβ and/or C/EBPδ gene. EMBO J 16:7432, 1997
28. Scott LM, Civin CI, Rorth P, Friedman AD: A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells. Blood 80:1725, 1992
29. Zhang DE, Fujioka KI, Hetherington CJ, Shapiro LH, Chen HM, Look AT, Tenen DG: Identification of a region which directs monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol 14:8085, 1994
30. Zhang DE, Hetherington CJ, Meyers S, Rhoades KL, Chen HM, Hiebert SW, Tenen DG: CCAAT enhancer binding protein (C/EBP) and AML1 (CBFα2) synergistically activate the M-CSF receptor promoter. Mol Cell Biol 16:1231, 1996
31. Smith LT, Hohaus S, Gonzalez DA, Dziennis SE, Tenen DG: PU.1 (Spi-1) and C/EBPα regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood 88:1234, 1996
32. Zhang P, Zhang D-E, Wang N, Heltherington CJ, Darlington GJ, Tenen DG: Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Nad Acad Sci USA 94:569, 1997
33. Natsuka S, Akira S, Nishio Y, Hashiomoto S, Sugita T, Isshiki H, Kishimoto T: Macrophage differentiation-specifc expression of NF-IL6, a transcription factor interleukin-6. Blood 79:460, 1992
34. Katz S, Kowenzleutz E, Müller C, Meese K, Ness SA, Leutz A: The NF-M transcription factor is related to C/EBP-beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells. EMBO J 12:1321, 1993
35. Ness SA, Kowenzleuz E, Casini T, Graf T, Leutz A: Myb and NF-M-combinatorial activators of myeloid genes in heterologous cell types. Genes Dev 7:749, 1993
36. Burk O, Mink S, Ringwald M, Klempnauer KH: Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors. EMBO J 12:2027, 1993
37. Chih DY, Chumakov AM, Park DJ, Silla AG, Koeffler HP: Modulation of mRNA expression of a novel human myeloid-selective CCAAT/enhancer binding protein gene (C/EBP∈). Blood 90:2987, 1997
38. Hohaus S, Petrovick MS, Voso MT, Sun Z, Zhang D-E, Tenen DG: PU.1 (Spi-1) and C/EBPα regulate the expression of the granulocyte-macrophage colony-stimulating factor receptor a gene. Mol Cell Biol 15:5830, 1995
39. Müller C, Kowenz-Leutz E, Grieser-Ade S, Graf T, Leutz A: NF-M (chicken C/EBPβ) induces eosinophilic differentiation and apoptosis in a hematopoietic progenitor cell line. EMBO J 14:6127, 1995
40. Zon LI, Yamaguchi Y, Yee K, Albee EA, Kimura A, Bennett JC, Orkin SH, Ackerman SJ: Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: Potential role in gene transcription. Blood 81:3234, 1993
41. Yamamoto M, Ko LJ, Leonard MW, Beug H, Orkin SH, Engel JD: Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Genes Dev 4:1650, 1990
42. Pevny L, Simon MC, Robertson E, Klein WH, Tsai SF, D'Agati V, Orkin SH, Constantini F: Erythroid differentiation in chimeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 349:257, 1991
43. Yamaguchi Y, Zon LI, Ackerman SJ, Yamamoto M, Suda T: Forced GATA-1 expression in the murine myeloid cell line M1: Induction of c-mpl expression and megakaryocytic/erythroid differentiation. Blood 91:450, 1998
44. Fishkoff SA: Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemic cells induced by culture under alkaline conditions. LeukRes 12:679, 1988
45. Kishi K, Toba K, Azegami T, Tsukada N, Uesugi Y, Masuko M, Niwano H, Hashimoto S, Sakaue M, Furukawa T, Koike T, Takahashi H, Maekawa T, Abe T, Aizawa Y: Hematopoietic cytokine dependent differentiation to eosinophils and neutrophils in newly established acute promyelocytic leukemia cell line with t(15; 17). Exp Hematol 26:135, 1998
46. Barker RL, Gleich GJ, Pease LR: Acid precursor revealed in human eosinophil granule major basic protein cDNA. J Exp Med 168:1493, 1988
47. phox cDNA and functional expression in a human X-linked chronic granulomatous disease cell line. Blood 87:2005, 1996
48. Takahashi H, Nukiwa T, Basset P, Crystal RG: Myelomonocytic cell lineage expression of the neutrophil elastase gene. J Biol Chem 263:456, 1989
49. Dorfman DM, Wilson DB, Bruns GA, Orkin SH: Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells. J Biol Chem 267:1279, 1992
50. Ho I-C, Vorhees P, Marin N, Oakley BK, Tsai S-F, Orkin SH, Leiden JM: Human GATA-3: A lineage-restricted transcription factor that regulates the expression of the T cell receptor a gene. EMBO J 10:1187, 1991
51. Antonson P, Xanthopoulos KG: Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein α (C/EBPα). Biochem Biophys Res Commun 215:106, 1995
52. Ray D, Culine S, Tavitian A, Moreau-Gachelin F: The human homologue of the putative proto-oncogene Spi-1: Characterization and expression in tumors. Oncogene 5:663, 1990
53. Mizushima S, Nagata S: pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res 18:5322, 1990
54. Andrews NC, Faller DV: A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cell. Nucleic Acids Res 19:2499, 1991
55. Chowdhury S, Gotoh T, Mori M, Takiguchi M: CCAAT/enhancer-binding protein β (C/EBPβ) binds and activitates while hepatocyte nuclear factor-4 (HNF-4) does not bind but represses the liver-type arginase promoter. Eur J Biochem 236:500, 1996
56. Li M-S, Sun Li, Satoh T, Fisher LM, Spry CJF: Human eosinophil major basic protein, a mediator of allergic inflammation, is expressed by alternative splicing from promoters. Biochem J 305:921, 1995
57. Tsang AP, Visvader JE, Turner CA, Fujiwara Y, Yu C, Weiss MJ, Crossley M, Orkin SH: FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90:109, 1997
58. Tanaka T, Akira S, Yoshida K, Umemoto M, Yoneda T, Shirafuji N, Fujiwara H, Suematsu S, Yoshida N, Kishimoto T: Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages. Cell 80:353, 1995
59. Yamanaka R, Barlow C, Lekstrom-Himes J, Castillo LH, Liu PP, Eckhaus M, Decker T, Wynshaw-Boris A, Xanthopoulos KG: Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proc Natl Acad Sci USA 94:13187, 1997
60. Nishio Y, Isshiki H, Kishimoto T, Akira S: A nuclear factor for interleukin-6 expression (NF-IL6) and the glucocorticoid receptor synergistically activate transcription of the rat α 1-acid glycoprotein gene via direct protein-protein interaction. Mol Cell Biol 13:1854, 1993
61. Oelgeschlager M, Nuchprayoon I, Luscher B, Friedman AD: C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter. Mol Cell Biol 16:4717, 1996
62. Williams SC, Baer M, Dillner AJ, Johnson PF: CRP2 (C/EBPβ) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity. EMBOJ 14:3170, 1995
63. Oelgeschlager M, Janknecht R, Krieg J, Schreek S, Luscher B: Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M. EMBO J 15:2771, 1996
64. Blobel GA, Nakajima T, Eckner R, Montminy M, Orkin SH: CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation. Proc Natl Acad Sci USA 95:2061, 1998
65. LeClair KP, Blanar MA, Sharp PA: The p50 subunit of NF-KB associates with the NF-IL6 transcription factor. Proc Natl Acad Sci USA 89:8145, 1992
66. Hsu W, Kerppola PL, Chen T, Curran T, Chen-Kiang S: Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region. Mol Cell Biol 14:268, 1994
67. Mink S, Kerber U, Klempnauer K-H: Interaction of C/EBPβ and v-Myb is required for synergistic activation of the mim-1 gene. Mol Cell Biol 16:1316, 1996
68. Sealy L, Malone D, Pawlak M: Regulation of the cfos serum response element by C/EBPβ. Mol Cell Biol 17:1744, 1997
69. Stein B, Cogswell PC, Baldwin AS: Functional and physical associations between NF-kB and C/EBP family members: A Rel domain-bZip interaction. Mol Cell Biol 13:3964, 1993
70. Henkel G, Brown MA: PU.1 and GATA: Components of a mast cell-specific interleukin 4 intronic enhancer. Proc Natl Acad Sci USA 91:7737, 1994
71. Deveaux S, Filipe A, Lemarchandel V, Ghysdael J, Remeo P-H, Mignotte V: Analysis of the thrombopoietin receptor (MPL) promoter implicates GATA and ets proteins in the coregulation of megakaryocyte-specific genes. Blood 87:4678, 1996
72. Kulessa H, Frampton J, Graf T: GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes Dev 9:1250, 1995
73. McNagny KM, Sieweke MH, Doderlein G, Graf T, Nerlov C: Regulation of eosinophil-specific gene expression by a QEBP-Ets complex and GATA-1. EMBOJ 17:3669, 1998
74. Nerlov C, McNagny KM, Doderlein G, Kowemz-Leutz E, Graf T: Distinct C/EBP functions are required for eosinophil lineage commitment and maturation. Genes Dev 12:2413, 1998