Mast cells as regulators of adaptive immunity to tumours

Clinical and Experimental Immunology

Volumn 155, Issue 2, 2009, Pages 140-146

  Wasiuk, A ^a   De Vries, V C ^a   Hartmann, K ^b   Roers, A ^b   Noelle, R J ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Acquired immunity; Immunosuppression; Mast cells; Tumour

Indexed keywords

ADAPTIVE IMMUNITY; CELL FUNCTION; CELL MIGRATION; CELLULAR DISTRIBUTION; CORRELATION ANALYSIS; DENDRITIC CELL; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOMODULATION; INNATE IMMUNITY; MAST CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION; TUMOR ESCAPE; TUMOR GROWTH;

ANIMALS; CELL COMMUNICATION; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; HUMANS; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; MAST CELLS; MICE; NEOPLASMS; T-LYMPHOCYTE SUBSETS; TUMOR ESCAPE;

EID: 58149279371     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03840.x     Document Type: Review

References (71)

1. Krishnaswamy G. Mast cells: methods and protocols. New York : Humana Press, 2005.
2. Sayed BA, Christy A, Quirion MR, Brown MA. The master switch: the role of mast cells in autoimmunity and tolerance. Annu Rev Immunol 2008 26 : 705 39.
3. Christy AL, Brown MA. The multitasking mast cell: positive and negative roles in the progression of autoimmunity. J Immunol 2007 179 : 2673 9.
4. Metz M, Grimbaldeston MA, Nakae S et al. Mast cells in the promotion and limitation of chronic inflammation. Immunol Rev 2007 217 : 304 28.
5. Murdoch C, Muthana M, Coffelt SB et al. The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer 2008 8 : 618 31.
6. Weller K, Foitzik K, Paus R et al. Mast cells are required for normal healing of skin wounds in mice. FASEB J 2006 20 : 2366 8.
7. Busse W. Mechanisms and advances in allergic diseases. J Allergy Clin Immunol 2000 105 : 593 8.
8. Nelson KC, Zhao M, Schroeder PR et al. Role of different pathways of the complement cascade in experimental bullous pemphigoid. J Clin Invest 2006 116 : 2892 900.
9. Nigrovic PA, Lee DM. Synovial mast cells: role in acute and chronic arthritis. Immunol Rev 2007 217 : 19 37.
10. Suto H, Nakae S, Kakurai M et al. Mast cell-associated TNF promotes dendritic cell migration. J Immunol 2006 176 : 4102 12.
11. Lu LF, Lind EF, Gondek DC et al. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature 2006 442 : 997 1002.
12. Hart PH, Grimbaldeston MA, Swift GJ et al. Dermal mast cells determine susceptibility to ultraviolet B-induced systemic suppression of contact hypersensitivity responses in mice. J Exp Med 1998 187 : 2045 53.
13. Grimbaldeston MA, Nakae S, Kalesnikoff J et al. Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. Nat Immunol 2007 8 : 1095 104.
14. Depinay N, Hacini F, Beghdadi W et al. Mast cell-dependent down-regulation of antigen-specific immune responses by mosquito bites. J Immunol 2006 176 : 4141 6.
15. Gurish MF, Boyce JA. Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell. J Allergy Clin Immunol 2006 117 : 1285 91.
16. Abbas AK, Lichtman AH. Cellular and molecular immunology, 5th edn. Philadelphia, PA : Saunders, 2003.
17. Theoharides TC, Kempuraj D, Tagen M et al. Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol Rev 2007 217 : 65 78.
18. Theoharides TC, Bondy PK, Tsakalos ND et al. Differential release of serotonin and histamine from mast cells. Nature 1982 297 : 229 31.
19. Leal-Berumen I, Conlon P, Marshall JS. IL-6 production by rat peritoneal mast cells is not necessarily preceded by histamine release and can be induced by bacterial lipopolysaccharide. J Immunol 1994 152 : 5468 76.
20. Grimbaldeston MA, Chen CC, Piliponsky AM et al. Mast cell-deficient W-sash c-kit mutant KitW-sh/W-sh mice as a model for investigating mast cell biology in vivo. Am J Pathol 2005 167 : 835 48.
21. Kitamura Y, Go S, Hatanaka K. Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation. Blood 1978 52 : 447 52.
22. Scholten J, Hartmann K, Gerbaulet A et al. Mast cell-specific Cre/loxP-mediated recombination in vivo. Transgenic Res 2008 17 : 307 15.
23. Opferman JT, Letai A, Beard C et al. Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1. Nature 2003 426 : 671 6.
24. Buch T, Heppner FL, Tertilt C et al. A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat Methods 2005 2 : 419 26.
25. Musch W, Wege AK, Mannel DN et al. Generation and characterization of alpha-chymase-Cre transgenic mice. Genesis 2008 46 : 163 6.
26. Westphal E. Uber mastzellen. Berlin : Hirschwald Press, 1891.
27. Imada A, Shijubo N, Kojima H et al. Mast cells correlate with angiogenesis and poor outcome in stage I lung adenocarcinoma. Eur Respir J 2000 15 : 1087 93.
28. Takanami I, Takeuchi K, Naruke M. Mast cell density is associated with angiogenesis and poor prognosis in pulmonary adenocarcinoma. Cancer 2000 88 : 2686 92.
29. Ch'ng S, Wallis RA, Yuan L et al. Mast cells and cutaneous malignancies. Mod Pathol 2006 19 : 149 59.
30. Amini RM, Aaltonen K, Nevanlinna H et al. Mast cells and eosinophils in invasive breast carcinoma. BMC Cancer 2007 7 : 165.
31. Lachter J, Stein M, Lichtig C et al. Mast cells in colorectal neoplasias and premalignant disorders. Dis Colon Rectum 1995 38 : 290 3.
32. Theoharides TC, Conti P. Mast cells: the JEKYLL and HYDE of tumor growth. Trends Immunol 2004 25 : 235 41.
33. Coussens LM, Raymond WW, Bergers G et al. Inflammatory cells up-regualate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 1999 13 : 1382 97.
34. Gounaris E, Erdman S, Restaino C et al. Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci USA 2007 104 : 19977 82.
35. Nakayama T, Yao L, Tosato G. Mast cell-derived angiopoietin-1 plays a critical role in the growth of plasma cell tumors. J Clin Invest 2004 114 : 1317 25.
36. Starkey JR, Crowle PK, Taubenberger S. Mast-cell-deficient W/Wv mice exhibit a decreased rate of tumor angiogenesis. Int J Cancer 1988 42 : 48 52.
37. Huang B, Lei Z, Zhang GM et al. SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood 2008 112 : 1269 79.
38. Munn DH, Mellor AL. The tumor-draining lymph node as an immune-privileged site. Immunol Rev 2006 213 : 146 58.
39. Cuenca A, Cheng F, Wang H. Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens. Cancer Res 2003 63 : 9007 15.
40. Gajewski TF, Meng Y, Blank C et al. Immune resistance orchestrated by the tumor microenvironment. Immunol Rev 2006 213 : 131 45.
41. Ochsenbein AF, Klenerman P, Karrer U et al. Immune surveillance against a solid tumor fails because of immunological ignorance. Proc Natl Acad Sci USA 1999 96 : 2233 8.
42. Sotomayor EM, Borrello I, Rattis DM et al. Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression. Blood 2001 98 : 1070 7.
43. Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 2006 6 : 295 307.
44. Chaux P, Favre N, Martin M et al. Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats. Int J Cancer 1997 72 : 619 24.
45. Scandella E, Men Y, Gillessen S et al. Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells. Blood 2002 100 : 1354 61.
46. Gosset P, Bureau F, Angeli V et al. Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. J Immunol 2003 170 : 4943 52.
47. Hammad H, de Heer HJ, Soullie T et al. Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1. J Immunol 2003 171 : 3936 40.
48. Yen JH, Khayrullina T, Ganea D. PGE2-induced metalloproteinase-9 is essential for dendritic cell migration. Blood 2007 111 : 260 70.
49. Angeli V, Faveeuw C, Roye O et al. Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection. J Exp Med 2001 193 : 1135 47.
50. Heib V, Becker M, Warger T et al. Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice. Blood 2007 110 : 946 53.
51. Walsh LJ. Ultraviolet B irradiation of skin induces mast cell degranulation and release of tumor necrosis factor-alpha. Immunol Cell Biol 1995 73 : 226 33.
52. Hart PH, Grimbaldeston MA, FInlay-Jones JJ. Sunlight, immunosuppression and skin cancer: role of histamine and mast cells. Clin Exp Pharmacol Physiol 2001 28 : 1 8.
53. Hart PH, Townley SL, Grimbaldeston MA et al. Mast cell, neuropeptides, histamine, and prostaglandins in UV-induced systemic immunosuppression. Methods 2002 28 : 79 89.
54. Idzko M, la Sala A, Ferrari D et al. Expression and function of histamine receptors in human monocyte-derived dendritic cells. J Allergy Clin Immunol 2002 109 : 839 46.
55. Ohtani T, Aiba S, Mizuashi M et al. H1 and H2 histamine receptors are absent on Langerhans cells and present on dermal dendritic cells. J Invest Dermatol 2003 121 : 1073 9.
56. Amaral MM, Davio C, Ceballos A et al. Histamine improves antigen uptake and cross-presentation by dendritic cells. J Immunol 2007 179 : 7891 8.
57. Gutzmer R, Diestel C, Mommert S et al. Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. J Immunol 2005 174 : 5224 32.
58. Gombert M, Dieu-Nosjean MC, Winterberg F et al. CCL1-CCR8 interactions: an axis mediating the recruitment of T cells and Langerhans-type dendritic cells to sites of atopic skin inflammation. J Immunol 2005 174 : 5082 91.
59. Wedemeyer J, Galli SJ. Decreased susceptibility of mast cell-deficient KitW/KitW-v mice to the development of 1, 2-dimethylhydrazine-induced intestinal tumors. Lab Invest 2005 85 : 388 96.
60. Askenasy N, Kaminitz A, Yarkoni S. Mechanisms of T regulatory cell function. Autoimmun Rev 2008 7 : 370 5.
61. Aune TM, Golden HW, McGrath KM. Inhibitors of serotonin synthesis and antagonists of serotonin 1A receptors inhibit T lymphocyte function in vitro and cell-mediated immunity in vivo. J Immunol 1994 153 : 489 98.
62. Laberge S, Cruikshank WW, Beer DJ et al. Secretion of IL-16 (lymphocyte chemoattractant factor) from serotonin-stimulated CD8+ T cells in vitro. J Immunol 1996 156 : 310 5.
63. León-Ponte M, Ahern GP, O'Connell PJ. Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor. Blood 2007 109 : 3139 46.
64. Nakae S, Suto H, Iikura M et al. Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF. J Immunol 2006 176 : 2238 48.
65. Keir ME, Butte MJ, Freeman GJ et al. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol 2008 26.
66. Zou W, Chen L. Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol 2008 8 : 467 77.
67. Aubin F. Mechanisms involved in ultraviolet light-induced immunosuppression. Eur J Dermatol 2003 13 : 515 23.
68. Nordlund JJ, Askenase PW. The effect of histamine, antihistamine, and mast cell stabilizer on the growth of Cloudman melanoma cells in DBA/2 mice. J Invest Dermatol 1983 81 : 28 31.
69. Boerma M, Fiser WP, Hoyt G et al. Influence of mast cells on outcome after heterotopic cardiac transplantation in rats. Transpl Int 2007 20 : 256 65.
70. Colvin RB, Dvorak HF. Basophils and mast cells in renal allograft rejection [Letter Lancet 1974 1 : 212 4.
71. Yousem SA. The potential role of mast cells in lung allograft rejection. Hum Pathol 1997 28 : 179 82.