Platonin inhibits LPS-induced NF-κB by preventing activation of Akt and IKKβ in human PBMC

Inflammation Research

Volumn 57, Issue 12, 2008, Pages 601-606

  Shao, D Z ^a   Lin, M ^b  

^a CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

B; Akt kinase; Anti inflammation; Human peripheral blood monocytes cells (PBMC); I B kinase (IKK ); Lipopolysaccharide (LPS); NF; Platonin(PL)

Indexed keywords

CYCLOOXYGENASE 2; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; PLATONIN; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; PERIPHERAL BLOOD MONONUCLEAR CELL; SIGNAL TRANSDUCTION;

CYCLOOXYGENASE 2; ENZYME ACTIVATION; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTO-ONCOGENE PROTEINS C-AKT; THIAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58149105592     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-008-8053-2     Document Type: Article

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