-
1
-
-
0027401203
-
Mutations in Cu/Zn superoxide-dismutase gene are associated with familial amyotrophic-lateral-sclerosis
-
Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldson D., Goto J., Oregan J.P., Deng H.X., Rahmani Z., Krizus A., Mckennayasek D., Cayabyab A., Gaston S.M., Berger R., Tanzi R.E., Halperin J.J., Herzfeldt B., Vandenbergh R., Hung W.Y., Bird T., Deng G., Mulder D.W., Smyth C., Laing N.G., Soriano E., Pericakvance M.A., Haines J., Rouleau G.A., Gusella J.S., Horvitz H.R., and Brown R.H. Mutations in Cu/Zn superoxide-dismutase gene are associated with familial amyotrophic-lateral-sclerosis. Nature 362 (1993) 59-62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
Oregan, J.P.9
Deng, H.X.10
Rahmani, Z.11
Krizus, A.12
Mckennayasek, D.13
Cayabyab, A.14
Gaston, S.M.15
Berger, R.16
Tanzi, R.E.17
Halperin, J.J.18
Herzfeldt, B.19
Vandenbergh, R.20
Hung, W.Y.21
Bird, T.22
Deng, G.23
Mulder, D.W.24
Smyth, C.25
Laing, N.G.26
Soriano, E.27
Pericakvance, M.A.28
Haines, J.29
Rouleau, G.A.30
Gusella, J.S.31
Horvitz, H.R.32
Brown, R.H.33
more..
-
2
-
-
0028918944
-
Identification of new mutations in the Cu/Zn superoxide-dismutase gene of patients with familial amyotrophic-lateral-sclerosis
-
Pramatarova A., Figlewicz D.A., Krizus A., Han F.Y., Ceballospicot I., Nicole A., Dib M., Meininger V., Brown R.H., and Rouleau G.A. Identification of new mutations in the Cu/Zn superoxide-dismutase gene of patients with familial amyotrophic-lateral-sclerosis. Am. J. Hum. Genet. 56 (1995) 592-596
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 592-596
-
-
Pramatarova, A.1
Figlewicz, D.A.2
Krizus, A.3
Han, F.Y.4
Ceballospicot, I.5
Nicole, A.6
Dib, M.7
Meininger, V.8
Brown, R.H.9
Rouleau, G.A.10
-
3
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: insights from genetics
-
Pasinelli P., and Brown R.H. Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat. Rev. Neurosci. 7 (2006) 710-723
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
4
-
-
33751003518
-
Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target
-
Barber S.C., Mead R.J., and Shaw P.J. Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochim. Biophys. Acta 1762 (2006) 1051-1067
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 1051-1067
-
-
Barber, S.C.1
Mead, R.J.2
Shaw, P.J.3
-
5
-
-
0031784348
-
Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Andrus P.K., Fleck T.J., Gurney M.E., and Hall E.D. Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis. J. Neurochem. 71 (1998) 2041-2048
-
(1998)
J. Neurochem.
, vol.71
, pp. 2041-2048
-
-
Andrus, P.K.1
Fleck, T.J.2
Gurney, M.E.3
Hall, E.D.4
-
6
-
-
18144398928
-
Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis
-
Casoni F., Basso M., Massignan T., Gianazza E., Cheroni C., Salmona M., Bendotti C., and Bonetto V. Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis. J. Biol. Chem. 280 (2005) 16295-16304
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16295-16304
-
-
Casoni, F.1
Basso, M.2
Massignan, T.3
Gianazza, E.4
Cheroni, C.5
Salmona, M.6
Bendotti, C.7
Bonetto, V.8
-
7
-
-
22544448129
-
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice-a model of familial amyotrophic lateral sclerosis
-
Poon H.F., Hensley K., Thongboonkerd V., Merchant M.L., Lynn B.C., Pierce W.M., Klein J.B., Calabrese V., and Butterfield D.A. Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice-a model of familial amyotrophic lateral sclerosis. Free Radic. Biol. Med. 39 (2005) 453-462
-
(2005)
Free Radic. Biol. Med.
, vol.39
, pp. 453-462
-
-
Poon, H.F.1
Hensley, K.2
Thongboonkerd, V.3
Merchant, M.L.4
Lynn, B.C.5
Pierce, W.M.6
Klein, J.B.7
Calabrese, V.8
Butterfield, D.A.9
-
8
-
-
33846430885
-
Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model
-
Shibata N., Kawaguchi M., Uchida K., Kakita A., Takahashi H., Nakano R., Fujimura H., Sakoda S., Ihara Y., Nobukuni K., Takehisa Y., Kuroda S., Kokubo Y., Kuzuhara S., Honma T., Mochizuki Y., Mizutani T., Yamada S., Toi S., Sasaki S., Iwata M., Hirano A., Yamamoto T., Kato Y., Sawada T., and Kobayashi M. Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model. Neuropathology 27 (2007) 49-61
-
(2007)
Neuropathology
, vol.27
, pp. 49-61
-
-
Shibata, N.1
Kawaguchi, M.2
Uchida, K.3
Kakita, A.4
Takahashi, H.5
Nakano, R.6
Fujimura, H.7
Sakoda, S.8
Ihara, Y.9
Nobukuni, K.10
Takehisa, Y.11
Kuroda, S.12
Kokubo, Y.13
Kuzuhara, S.14
Honma, T.15
Mochizuki, Y.16
Mizutani, T.17
Yamada, S.18
Toi, S.19
Sasaki, S.20
Iwata, M.21
Hirano, A.22
Yamamoto, T.23
Kato, Y.24
Sawada, T.25
Kobayashi, M.26
more..
-
9
-
-
33644629020
-
Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models
-
Kato S., Kato M., Abe Y., Matsumura T., Nishino T., Aoki M., Itoyama Y., Asayama K., Awaya A., Hirano A., and Ohama E. Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models. Acta Neuropathol. 110 (2005) 101-112
-
(2005)
Acta Neuropathol.
, vol.110
, pp. 101-112
-
-
Kato, S.1
Kato, M.2
Abe, Y.3
Matsumura, T.4
Nishino, T.5
Aoki, M.6
Itoyama, Y.7
Asayama, K.8
Awaya, A.9
Hirano, A.10
Ohama, E.11
-
10
-
-
7244239105
-
Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis
-
Strey C.W., Spellman D., Stieber A., Gonatas J.O., Wang X.S., Lambris J.D., and Gonatas N.K. Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis. Am. J. Pathol. 165 (2004) 1701-1718
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 1701-1718
-
-
Strey, C.W.1
Spellman, D.2
Stieber, A.3
Gonatas, J.O.4
Wang, X.S.5
Lambris, J.D.6
Gonatas, N.K.7
-
11
-
-
21944454604
-
Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS
-
Kirby J., Halligan E., Baptista M.J., Allen S., Heath P.R., Holden H., Barber S.C., Loynes C.A., Wood-Allum C.A., Lunec J., and Shaw P.J. Mutant SOD1 alters the motor neuronal transcriptome: implications for familial ALS. Brain 128 (2005) 1686-1706
-
(2005)
Brain
, vol.128
, pp. 1686-1706
-
-
Kirby, J.1
Halligan, E.2
Baptista, M.J.3
Allen, S.4
Heath, P.R.5
Holden, H.6
Barber, S.C.7
Loynes, C.A.8
Wood-Allum, C.A.9
Lunec, J.10
Shaw, P.J.11
-
12
-
-
0035085455
-
Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays
-
Malaspina A., Kaushik N., and de Belleroche J. Differential expression of 14 genes in amyotrophic lateral sclerosis spinal cord detected using gridded cDNA arrays. J. Neurochem. 77 (2001) 132-145
-
(2001)
J. Neurochem.
, vol.77
, pp. 132-145
-
-
Malaspina, A.1
Kaushik, N.2
de Belleroche, J.3
-
13
-
-
38749113921
-
Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model
-
Gonzalez de Aguilar J.L., Niederhauser-Wiederkehr C., Halter B., De Tapia M., Di Scala F., Demougin P., Dupuis L., Primig M., Meininger V., and Loeffler J.P. Gene profiling of skeletal muscle in an amyotrophic lateral sclerosis mouse model. Physiol. Genomics 32 (2008) 207-218
-
(2008)
Physiol. Genomics
, vol.32
, pp. 207-218
-
-
Gonzalez de Aguilar, J.L.1
Niederhauser-Wiederkehr, C.2
Halter, B.3
De Tapia, M.4
Di Scala, F.5
Demougin, P.6
Dupuis, L.7
Primig, M.8
Meininger, V.9
Loeffler, J.P.10
-
14
-
-
0032512137
-
Up-regulation of thioredoxin expression in motor neurons after nerve injury
-
Mansur K., Iwahashi Y., Kiryu-Seo S., Su Q., Namikawa K., Yodoi J., and Kiyama H. Up-regulation of thioredoxin expression in motor neurons after nerve injury. Mol. Brain Res. 62 (1998) 86-91
-
(1998)
Mol. Brain Res.
, vol.62
, pp. 86-91
-
-
Mansur, K.1
Iwahashi, Y.2
Kiryu-Seo, S.3
Su, Q.4
Namikawa, K.5
Yodoi, J.6
Kiyama, H.7
-
15
-
-
0035584857
-
Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
-
Nordberg J., and Arner E.S. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 31 (2001) 1287-1312
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 1287-1312
-
-
Nordberg, J.1
Arner, E.S.2
-
17
-
-
0034652113
-
Thioredoxin reductase
-
Mustacich D., and Powis G. Thioredoxin reductase. Biochem. J. 346 Pt 1 (2000) 1-8
-
(2000)
Biochem. J.
, vol.346
, Issue.PART 1
, pp. 1-8
-
-
Mustacich, D.1
Powis, G.2
-
18
-
-
0029994196
-
A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeast Schizosaccharomyces pombe
-
Casso D., and Beach D. A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 252 (1996) 518-529
-
(1996)
Mol. Gen. Genet.
, vol.252
, pp. 518-529
-
-
Casso, D.1
Beach, D.2
-
19
-
-
33845432813
-
Contribution of thioredoxin reductase to T-cell mitogenesis and NF-kappaB DNA-binding promoted by selenite
-
Ueno H., Kajihara H., Nakamura H., Yodoi J., and Nakamuro K. Contribution of thioredoxin reductase to T-cell mitogenesis and NF-kappaB DNA-binding promoted by selenite. Antioxid. Redox Signaling 9 (2007) 115-121
-
(2007)
Antioxid. Redox Signaling
, vol.9
, pp. 115-121
-
-
Ueno, H.1
Kajihara, H.2
Nakamura, H.3
Yodoi, J.4
Nakamuro, K.5
-
20
-
-
0037462640
-
The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone: a novel mechanism for defense against oxidative stress
-
Xia L., Nordman T., Olsson J.M., Damdimopoulos A., Bjorkhem-Bergman L., Nalvarte I., Eriksson L.C., Arner E.S., Spyrou G., and Bjornstedt M. The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone: a novel mechanism for defense against oxidative stress. J. Biol. Chem. 278 (2003) 2141-2146
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2141-2146
-
-
Xia, L.1
Nordman, T.2
Olsson, J.M.3
Damdimopoulos, A.4
Bjorkhem-Bergman, L.5
Nalvarte, I.6
Eriksson, L.C.7
Arner, E.S.8
Spyrou, G.9
Bjornstedt, M.10
-
21
-
-
0037507286
-
Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine
-
Anestal K., and Arner E.S. Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine. J. Biol. Chem. 278 (2003) 15966-15972
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15966-15972
-
-
Anestal, K.1
Arner, E.S.2
-
22
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M., Nishitoh H., Fujii M., Takeda K., Tobiume K., Sawada Y., Kawabata M., Miyazono K., and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17 (1998) 2596-2606
-
(1998)
EMBO J.
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
23
-
-
0000385805
-
Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin
-
Chae H.Z., Kang S.W., and Rhee S.G. Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin. Methods Enzymol. 300 (1999) 219-226
-
(1999)
Methods Enzymol.
, vol.300
, pp. 219-226
-
-
Chae, H.Z.1
Kang, S.W.2
Rhee, S.G.3
-
24
-
-
0027214048
-
Mercury and selenium contents in amyotrophic lateral sclerosis in Hokkaido, the northernmost island of Japan
-
Moriwaka F., Satoh H., Ejima A., Watanabe C., Tashiro K., Hamada T., Matsumoto A., Shima K., Yanagihara T., Fukazawa T., et al. Mercury and selenium contents in amyotrophic lateral sclerosis in Hokkaido, the northernmost island of Japan. J. Neurol. Sci. 118 (1993) 38-42
-
(1993)
J. Neurol. Sci.
, vol.118
, pp. 38-42
-
-
Moriwaka, F.1
Satoh, H.2
Ejima, A.3
Watanabe, C.4
Tashiro, K.5
Hamada, T.6
Matsumoto, A.7
Shima, K.8
Yanagihara, T.9
Fukazawa, T.10
-
25
-
-
0036089834
-
Environmental exposure to trace elements and risk of amyotrophic lateral sclerosis: a population-based case-control study
-
Bergomi M., Vinceti M., Nacci G., Pietrini V., Bratter P., Alber D., Ferrari A., Vescovi L., Guidetti D., Sola P., Malagu S., Aramini C., and Vivoli G. Environmental exposure to trace elements and risk of amyotrophic lateral sclerosis: a population-based case-control study. Environ. Res. 89 (2002) 116-123
-
(2002)
Environ. Res.
, vol.89
, pp. 116-123
-
-
Bergomi, M.1
Vinceti, M.2
Nacci, G.3
Pietrini, V.4
Bratter, P.5
Alber, D.6
Ferrari, A.7
Vescovi, L.8
Guidetti, D.9
Sola, P.10
Malagu, S.11
Aramini, C.12
Vivoli, G.13
-
27
-
-
14044275133
-
Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease
-
Soares M.L., Coelho T., Sousa A., Batalov S., Conceicao I., Sales-Luis M.L., Ritchie M.D., Williams S.M., Nievergelt C.M., Schork N.J., Saraiva M.J., and Buxbaum J.N. Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease. Hum. Mol. Genet. 14 (2005) 543-553
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 543-553
-
-
Soares, M.L.1
Coelho, T.2
Sousa, A.3
Batalov, S.4
Conceicao, I.5
Sales-Luis, M.L.6
Ritchie, M.D.7
Williams, S.M.8
Nievergelt, C.M.9
Schork, N.J.10
Saraiva, M.J.11
Buxbaum, J.N.12
-
28
-
-
0033671717
-
Dominant modifier DFNM1 suppresses recessive deafness DFNB26
-
Riazuddin S., Castelein C.M., Ahmed Z.M., Lalwani A.K., Mastroianni M.A., Naz S., Smith T.N., Liburd N.A., Friedman T.B., Griffith A.J., Riazuddin S., and Wilcox E.R. Dominant modifier DFNM1 suppresses recessive deafness DFNB26. Nat. Genet. 26 (2000) 431-434
-
(2000)
Nat. Genet.
, vol.26
, pp. 431-434
-
-
Riazuddin, S.1
Castelein, C.M.2
Ahmed, Z.M.3
Lalwani, A.K.4
Mastroianni, M.A.5
Naz, S.6
Smith, T.N.7
Liburd, N.A.8
Friedman, T.B.9
Griffith, A.J.10
Riazuddin, S.11
Wilcox, E.R.12
-
29
-
-
58049214281
-
Genetic mapping of a modifier gene that delays ALS onset in a transgenic mouse model
-
Kunst C.B., Messer L., Gordon J., Haines J.L., and Patterson D. Genetic mapping of a modifier gene that delays ALS onset in a transgenic mouse model. Am. J. Hum. Genet. 67 (2000) 54
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 54
-
-
Kunst, C.B.1
Messer, L.2
Gordon, J.3
Haines, J.L.4
Patterson, D.5
-
30
-
-
0036235860
-
Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene
-
Giess R., Holtmann B., Braga M., Grimm T., Muller-Myhsok B., Toyka K.V., and Sendtner M. Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. Am. J. Hum. Genet. 70 (2002) 1277-1286
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 1277-1286
-
-
Giess, R.1
Holtmann, B.2
Braga, M.3
Grimm, T.4
Muller-Myhsok, B.5
Toyka, K.V.6
Sendtner, M.7
-
31
-
-
0029142863
-
Investigation of a null mutation of the CNTF gene in familial amyotrophic-lateral-sclerosis
-
Orrell R.W., King A.W., Lane R.J.M., and Debelleroche J.S. Investigation of a null mutation of the CNTF gene in familial amyotrophic-lateral-sclerosis. J. Neurol. Sci. 132 (1995) 126-128
-
(1995)
J. Neurol. Sci.
, vol.132
, pp. 126-128
-
-
Orrell, R.W.1
King, A.W.2
Lane, R.J.M.3
Debelleroche, J.S.4
-
32
-
-
0038799979
-
Ciliary neurotrophic factor genotype does not influence clinical phenotype in amyotrophic lateral sclerosis
-
Al-Chalabi A., Scheffler M.D., Smith B.N., Parton M.J., Cudkowicz M.E., Andersen P.M., Hayden D.L., Hansen V.K., Turner M.R., Shaw C.E., Leigh P.N., and Brown R.H. Ciliary neurotrophic factor genotype does not influence clinical phenotype in amyotrophic lateral sclerosis. Ann. Neurol. 54 (2003) 130-134
-
(2003)
Ann. Neurol.
, vol.54
, pp. 130-134
-
-
Al-Chalabi, A.1
Scheffler, M.D.2
Smith, B.N.3
Parton, M.J.4
Cudkowicz, M.E.5
Andersen, P.M.6
Hayden, D.L.7
Hansen, V.K.8
Turner, M.R.9
Shaw, C.E.10
Leigh, P.N.11
Brown, R.H.12
-
33
-
-
0036885011
-
D90A-SOD1 mediated amyotrophic lateral sclerosis: a single founder for all cases with evidence for a cis-acting disease modifier in the recessive haplotype
-
Parton M.J., Broom W., Andersen P.M., Al-Chalabi A., Nigel Leigh P., Powell J.F., and Shaw C.E. D90A-SOD1 mediated amyotrophic lateral sclerosis: a single founder for all cases with evidence for a cis-acting disease modifier in the recessive haplotype. Hum. Mutat. 20 (2002) 473
-
(2002)
Hum. Mutat.
, vol.20
, pp. 473
-
-
Parton, M.J.1
Broom, W.2
Andersen, P.M.3
Al-Chalabi, A.4
Nigel Leigh, P.5
Powell, J.F.6
Shaw, C.E.7
-
34
-
-
33747047814
-
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
-
Wu D.C., Re D.B., Nagai M., Ischiropoulo H., and Przedborski S. The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc. Natl. Acad. Sci. USA 103 (2006) 12132-12137
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 12132-12137
-
-
Wu, D.C.1
Re, D.B.2
Nagai, M.3
Ischiropoulo, H.4
Przedborski, S.5
-
35
-
-
34948822926
-
Redox modifier genes in amyotrophic lateral sclerosis in mice
-
Marden J.J., Harraz M.M., Williams A.J., Nelson K., Luo M., Paulson H., and Engelhardt J.F. Redox modifier genes in amyotrophic lateral sclerosis in mice. J. Clin. Invest. 117 (2007) 2913-2919
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2913-2919
-
-
Marden, J.J.1
Harraz, M.M.2
Williams, A.J.3
Nelson, K.4
Luo, M.5
Paulson, H.6
Engelhardt, J.F.7
-
36
-
-
0031466983
-
From genotypes to genes: doubling the sample size
-
Sasieni P.D. From genotypes to genes: doubling the sample size. Biometrics 53 (1997) 1253-1261
-
(1997)
Biometrics
, vol.53
, pp. 1253-1261
-
-
Sasieni, P.D.1
-
37
-
-
0002907949
-
The Interaction of selection and linkage. I. General considerations, heterotic models
-
Lewontin R.C. The Interaction of selection and linkage. I. General considerations, heterotic models. Genetics 49 (1964) 49-67
-
(1964)
Genetics
, vol.49
, pp. 49-67
-
-
Lewontin, R.C.1
-
38
-
-
33646226097
-
Linkage disequilibrium in finite populations
-
Hill W.G., and Robertson A. Linkage disequilibrium in finite populations. Theor. Appl. Genet. 38 (1968) 226-231
-
(1968)
Theor. Appl. Genet.
, vol.38
, pp. 226-231
-
-
Hill, W.G.1
Robertson, A.2
-
40
-
-
0242691208
-
A comparison of Bayesian methods for haplotype reconstruction from population genotype data
-
Stephens M., and Donnelly P. A comparison of Bayesian methods for haplotype reconstruction from population genotype data. Am. J. Hum. Genet. 73 (2003) 1162-1169
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 1162-1169
-
-
Stephens, M.1
Donnelly, P.2
-
41
-
-
34547622688
-
Imputation-based analysis of association studies: candidate regions and quantitative traits
-
Servin B., and Stephens M. Imputation-based analysis of association studies: candidate regions and quantitative traits. PLoS Genet. 3 (2007) 1296-1308
-
(2007)
PLoS Genet.
, vol.3
, pp. 1296-1308
-
-
Servin, B.1
Stephens, M.2
-
43
-
-
33344458848
-
A comparison of phasing algorithms for trios and unrelated individuals
-
Marchini J., Cutler D., Patterson N., Stephens M., Eskin E., Halperin E., Lin S., Qin Z.S., Munro H.M., Abecasis G.R., Donnelly P., and Consortium I.H. A comparison of phasing algorithms for trios and unrelated individuals. Am. J. Hum. Genet. 78 (2006) 437-450
-
(2006)
Am. J. Hum. Genet.
, vol.78
, pp. 437-450
-
-
Marchini, J.1
Cutler, D.2
Patterson, N.3
Stephens, M.4
Eskin, E.5
Halperin, E.6
Lin, S.7
Qin, Z.S.8
Munro, H.M.9
Abecasis, G.R.10
Donnelly, P.11
Consortium, I.H.12
-
44
-
-
20944435890
-
Emerging roles of thioredoxin cycle enzymes in the central nervous system
-
Patenaude A., Murthy M.R.V., and Mirault M.E. Emerging roles of thioredoxin cycle enzymes in the central nervous system. Cell. Mol. Life Sci. 62 (2005) 1063-1080
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 1063-1080
-
-
Patenaude, A.1
Murthy, M.R.V.2
Mirault, M.E.3
-
45
-
-
44449119080
-
Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins
-
Benhar M., Forrester M.T., Hess D.T., and Stamler J.S. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 320 (2008) 1050-1054
-
(2008)
Science
, vol.320
, pp. 1050-1054
-
-
Benhar, M.1
Forrester, M.T.2
Hess, D.T.3
Stamler, J.S.4
-
46
-
-
39449105514
-
Protein carbonylation as a novel mechanism in redox signaling
-
Wong C.M., Cheema A.K., Zhang L.H., and Suzuki Y.J. Protein carbonylation as a novel mechanism in redox signaling. Circ. Res. 102 (2008) 310-318
-
(2008)
Circ. Res.
, vol.102
, pp. 310-318
-
-
Wong, C.M.1
Cheema, A.K.2
Zhang, L.H.3
Suzuki, Y.J.4
-
47
-
-
0242668686
-
Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling
-
Wood Z.A., Poole L.B., and Karplus P.A. Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science 300 (2003) 650-653
-
(2003)
Science
, vol.300
, pp. 650-653
-
-
Wood, Z.A.1
Poole, L.B.2
Karplus, P.A.3
-
48
-
-
44449139408
-
A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway
-
Kim S.Y., Kim T.J., and Lee K.Y. A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway. FEBS Lett. 582 (2008) 1913-1918
-
(2008)
FEBS Lett.
, vol.582
, pp. 1913-1918
-
-
Kim, S.Y.1
Kim, T.J.2
Lee, K.Y.3
-
49
-
-
34147123804
-
Ethnic variation in the incidence of ALS-a systematic review
-
Cronin S., Hardiman O., and Traynor B.J. Ethnic variation in the incidence of ALS-a systematic review. Neurology 68 (2007) 1002-1007
-
(2007)
Neurology
, vol.68
, pp. 1002-1007
-
-
Cronin, S.1
Hardiman, O.2
Traynor, B.J.3
-
50
-
-
0029433185
-
Epidemiology of ALS
-
Nelson L.M. Epidemiology of ALS. Clin. Neurosci. 3 (1996) 327-331
-
(1996)
Clin. Neurosci.
, vol.3
, pp. 327-331
-
-
Nelson, L.M.1
-
51
-
-
0028118641
-
Polypurine sequences within a downstream exon function as a splicing enhancer
-
Tanaka K., Watakabe A., and Shimura Y. Polypurine sequences within a downstream exon function as a splicing enhancer. Mol. Cell. Biol. 14 (1994) 1347-1354
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1347-1354
-
-
Tanaka, K.1
Watakabe, A.2
Shimura, Y.3
-
52
-
-
0032570693
-
Regulation of the fibroblast growth factor receptor 3 promoter and intron I enhancer by Sp1 family transcription factors
-
Mcewen D.G., and Ornitz D.M. Regulation of the fibroblast growth factor receptor 3 promoter and intron I enhancer by Sp1 family transcription factors. J. Biol. Chem. 273 (1998) 5349-5357
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5349-5357
-
-
Mcewen, D.G.1
Ornitz, D.M.2
-
53
-
-
0030579118
-
Identification of cis-acting elements involved in an alternative splicing of the amyloid precursor protein (APP) gene
-
Shibata A., Hattori M., Suda H., and Sakaki Y. Identification of cis-acting elements involved in an alternative splicing of the amyloid precursor protein (APP) gene. Gene 175 (1996) 203-208
-
(1996)
Gene
, vol.175
, pp. 203-208
-
-
Shibata, A.1
Hattori, M.2
Suda, H.3
Sakaki, Y.4
-
54
-
-
0024477261
-
On finding all suboptimal foldings of an RNA molecule
-
Zuker M. On finding all suboptimal foldings of an RNA molecule. Science 244 (1989) 48-52
-
(1989)
Science
, vol.244
, pp. 48-52
-
-
Zuker, M.1
-
56
-
-
0035976903
-
Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein
-
Ng C.J., Wadleigh D.J., Gangopadhyay A., Hama S., Grijalva V.R., Navab M., Fogelman A.M., and Reddy S.T. Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein. J. Biol. Chem. 276 (2001) 44444-44449
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 44444-44449
-
-
Ng, C.J.1
Wadleigh, D.J.2
Gangopadhyay, A.3
Hama, S.4
Grijalva, V.R.5
Navab, M.6
Fogelman, A.M.7
Reddy, S.T.8
-
57
-
-
0035287508
-
Modifier genes in mice and humans
-
Nadeau J.H. Modifier genes in mice and humans. Nat. Rev. Genet. 2 (2001) 165-174
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 165-174
-
-
Nadeau, J.H.1
-
58
-
-
20444504724
-
Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the Apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation
-
Furukawa Y., and O'Halloran T.V. Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the Apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation. J. Biol. Chem. 280 (2005) 17266-17274
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17266-17274
-
-
Furukawa, Y.1
O'Halloran, T.V.2
-
59
-
-
31544467869
-
Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models
-
Jonsson P.A., Graffmo K.S., Andersen P.M., Brannstrom T., Lindberg M., Oliveberg M., and Marklund S.L. Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models. Brain 129 (2006) 451-464
-
(2006)
Brain
, vol.129
, pp. 451-464
-
-
Jonsson, P.A.1
Graffmo, K.S.2
Andersen, P.M.3
Brannstrom, T.4
Lindberg, M.5
Oliveberg, M.6
Marklund, S.L.7
-
60
-
-
33646486372
-
Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice
-
Furukawa Y., Fu R.G., Deng H.X., Siddique T., and O'Halloran T.V. Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice. Proc. Natl. Acad. Sci. USA 103 (2006) 7148-7153
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 7148-7153
-
-
Furukawa, Y.1
Fu, R.G.2
Deng, H.X.3
Siddique, T.4
O'Halloran, T.V.5
-
61
-
-
26444471905
-
Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates
-
Matsumoto G., Stojanovic A., Holmberg C.I., Kim S., and Morimoto R.I. Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates. J. Cell Biol. 171 (2005) 75-85
-
(2005)
J. Cell Biol.
, vol.171
, pp. 75-85
-
-
Matsumoto, G.1
Stojanovic, A.2
Holmberg, C.I.3
Kim, S.4
Morimoto, R.I.5
-
62
-
-
33749563294
-
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
-
Atkin J.D., Farg M.A., Turner B.J., Tomas D., Lysaght J.A., Nunan J., Rembach A., Nagley P., Beart P.M., Cheema S.S., and Horne M.K. Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1. J. Biol. Chem. 281 (2006) 30152-30165
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30152-30165
-
-
Atkin, J.D.1
Farg, M.A.2
Turner, B.J.3
Tomas, D.4
Lysaght, J.A.5
Nunan, J.6
Rembach, A.7
Nagley, P.8
Beart, P.M.9
Cheema, S.S.10
Horne, M.K.11
-
63
-
-
0025331418
-
Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity
-
Lundstrom J., and Holmgren A. Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity. J. Biol. Chem. 265 (1990) 9114-9120
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 9114-9120
-
-
Lundstrom, J.1
Holmgren, A.2
-
64
-
-
33745315287
-
S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
-
Uehara T., Nakamura T., Yao D.D., Shi Z.Q., Gu Z.Z., Ma Y.L., Masliah E., Nomura Y., and Lipton S.A. S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature 441 (2006) 513-517
-
(2006)
Nature
, vol.441
, pp. 513-517
-
-
Uehara, T.1
Nakamura, T.2
Yao, D.D.3
Shi, Z.Q.4
Gu, Z.Z.5
Ma, Y.L.6
Masliah, E.7
Nomura, Y.8
Lipton, S.A.9
-
65
-
-
34347361680
-
Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen
-
Satoh M., Matter C.M., Ogita H., Takeshita K., Wang C.Y., Dorn G.W., and Liao J.K. Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen. Circulation 115 (2007) 3197-3204
-
(2007)
Circulation
, vol.115
, pp. 3197-3204
-
-
Satoh, M.1
Matter, C.M.2
Ogita, H.3
Takeshita, K.4
Wang, C.Y.5
Dorn, G.W.6
Liao, J.K.7
-
66
-
-
9444255256
-
Estradiol regulates the thioredoxin antioxidant system in the mouse uterus
-
Deroo B.J., Hewitt S.C., Peddada S.D., and Korach K.S. Estradiol regulates the thioredoxin antioxidant system in the mouse uterus. Endocrinology 145 (2004) 5485-5492
-
(2004)
Endocrinology
, vol.145
, pp. 5485-5492
-
-
Deroo, B.J.1
Hewitt, S.C.2
Peddada, S.D.3
Korach, K.S.4
-
67
-
-
33847176637
-
Increased incidence of FMO1 gene single nucleotide polymorphisms in sporadic amyotrophic lateral sclerosis
-
Cereda C., Gabanti E., Corato M., de Silvestri A., Alimonti D., Cova E., Malaspina A., and Ceroni M. Increased incidence of FMO1 gene single nucleotide polymorphisms in sporadic amyotrophic lateral sclerosis. Amyotrophic Lateral Scler. 7 (2006) 227-234
-
(2006)
Amyotrophic Lateral Scler.
, vol.7
, pp. 227-234
-
-
Cereda, C.1
Gabanti, E.2
Corato, M.3
de Silvestri, A.4
Alimonti, D.5
Cova, E.6
Malaspina, A.7
Ceroni, M.8
-
68
-
-
33748707208
-
Paraoxonase cluster polymorphisms are associated with sporadic ALS
-
Saeed M., Siddique N., Hung W.Y., Usacheva E., Liu E., Sufit R.L., Heller S.L., Haines J.L., Pericak-Vance M., and Siddique T. Paraoxonase cluster polymorphisms are associated with sporadic ALS. Neurology 67 (2006) 771-776
-
(2006)
Neurology
, vol.67
, pp. 771-776
-
-
Saeed, M.1
Siddique, N.2
Hung, W.Y.3
Usacheva, E.4
Liu, E.5
Sufit, R.L.6
Heller, S.L.7
Haines, J.L.8
Pericak-Vance, M.9
Siddique, T.10
-
69
-
-
33748678135
-
Paraoxonase gene polymorphisms and sporadic ALS
-
Slowik A., Tomik B., Wolkow P.P., Partyka D., Turaj W., Malecki M.T., Pera J., Dziedzic T., Szczudlik A., and Figlewicz D.A. Paraoxonase gene polymorphisms and sporadic ALS. Neurology 67 (2006) 766-770
-
(2006)
Neurology
, vol.67
, pp. 766-770
-
-
Slowik, A.1
Tomik, B.2
Wolkow, P.P.3
Partyka, D.4
Turaj, W.5
Malecki, M.T.6
Pera, J.7
Dziedzic, T.8
Szczudlik, A.9
Figlewicz, D.A.10
-
70
-
-
44349148784
-
Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease
-
Lee Y.M., Park S.H., Shin D.I., Hwang J.Y., Park B., Park Y.J., Lee T.H., Chae H.Z., Jin B.K., Oh T.H., and Oh Y.J. Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease. J. Biol. Chem. 283 (2008) 9986-9998
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9986-9998
-
-
Lee, Y.M.1
Park, S.H.2
Shin, D.I.3
Hwang, J.Y.4
Park, B.5
Park, Y.J.6
Lee, T.H.7
Chae, H.Z.8
Jin, B.K.9
Oh, T.H.10
Oh, Y.J.11
-
71
-
-
0036671827
-
Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span
-
Mitsui A., Hamuro J., Nakamura H., Kondo N., Hirabayashi Y., Ishizaki-Koizumi S., Hirakawa T., Inoue T., and Yodoi J. Overexpression of human thioredoxin in transgenic mice controls oxidative stress and life span. Antioxid. Redox Signaling 4 (2002) 693-696
-
(2002)
Antioxid. Redox Signaling
, vol.4
, pp. 693-696
-
-
Mitsui, A.1
Hamuro, J.2
Nakamura, H.3
Kondo, N.4
Hirabayashi, Y.5
Ishizaki-Koizumi, S.6
Hirakawa, T.7
Inoue, T.8
Yodoi, J.9
-
72
-
-
0033616616
-
Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage
-
Takagi Y., Mitsui A., Nishiyama A., Nozaki K., Sono H., Gon Y., Hashimoto N., and Yodoi J. Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage. Proc. Natl. Acad. Sci. USA 96 (1999) 4131-4136
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4131-4136
-
-
Takagi, Y.1
Mitsui, A.2
Nishiyama, A.3
Nozaki, K.4
Sono, H.5
Gon, Y.6
Hashimoto, N.7
Yodoi, J.8
-
73
-
-
0034075443
-
Excitotoxic hippocampal injury is attenuated in thioredoxin transgenic mice
-
Takagi Y., Hattori I., Nozaki K., Mitsui A., Ishikawa M., Hashimoto N., and Yodoi J. Excitotoxic hippocampal injury is attenuated in thioredoxin transgenic mice. J. Cereb. Blood Flow Metab. 20 (2000) 829-833
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 829-833
-
-
Takagi, Y.1
Hattori, I.2
Nozaki, K.3
Mitsui, A.4
Ishikawa, M.5
Hashimoto, N.6
Yodoi, J.7
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