The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone: A novel mechanism for defense against oxidative stress

Journal of Biological Chemistry

Volumn 278, Issue 4, 2003, Pages 2141-2146

  Xia, Ling ^a,b   Nordman, Tomas ^a,b   Olsson, Jerker M ^a   Damdimopoulos, Anastassios ^c   Björkhem Bergman, Linda ^a   Nalvarte, Ivan ^c   Eriksson, Lennart C ^a   Arnér, Elias S J ^c   Spyrou, Giannis ^b,c   Björnstedt, Mikael ^a,b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b SÖDERTÖRN UNIVERSITY   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; CELL CULTURE; LIPIDS; PH EFFECTS;

PEROXIDATION;

ENZYMES;

COMPLEMENTARY DNA; MESSENGER RNA; MUTANT PROTEIN; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SELENOPROTEIN; THIOREDOXIN; THIOREDOXIN REDUCTASE; UBIDECARENONE; UBIQUINONE; ANTIDOTE; ANTIOXIDANT; DRUG DERIVATIVE; THIOREDOXIN REDUCTASE 1; UBIQUINOL 10; UBIQUINOL-10; UBIQUINONE Q2;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CYTOSOL; DOSE TIME EFFECT RELATION; EMBRYO; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KIDNEY CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; ANIMAL; CELL LINE; CHEMISTRY; GENETIC TRANSFECTION; KINETICS; METABOLISM; MUTATION; PHYSIOLOGY; TIME;

ANIMALIA; ESCHERICHIA COLI; MAMMALIA;

ANIMALS; ANTIDOTES; ANTIOXIDANTS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESCHERICHIA COLI; HUMANS; KINETICS; MUTATION; OXIDATIVE STRESS; RATS; THIOREDOXIN REDUCTASE (NADPH); TIME FACTORS; TRANSFECTION; UBIQUINONE;

EID: 0037462640     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210456200     Document Type: Article

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