Modulation of the affinity and selectivity of RGS protein interaction with Gα subunits by a conserved asparagine/serine residue

Biochemistry

Volumn 38, Issue 24, 1999, Pages 7773-7779

  Posner, Bruce A ^a   Mukhopadhyay, Suchetana ^a   Tesmer, John J ^b   Gilman, Alfred G ^a   Ross, Elliott M ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; MUTANT PROTEIN; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEOLIPOSOME;

ANIMALS; ASPARAGINE; BINDING, COMPETITIVE; CONSERVED SEQUENCE; CYSTEINE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; GUANOSINE TRIPHOSPHATE; HUMANS; HYDROLYSIS; LYSINE; MUTAGENESIS, SITE-DIRECTED; PROLINE; PROTEIN BINDING; PROTEINS; RECEPTORS, CELL SURFACE; RGS PROTEINS; SERINE;

EID: 0033564683     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9906367     Document Type: Article

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