Structural diversity in the RGS domain and its interaction with heterotrimeric G protein α-subunits

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 17, 2008, Pages 6457-6462

  Soundararajan, Meera ^a   Willard, Francis S ^b   Kimple, Adam J ^b   Turnbull, Andrew P ^a   Ball, Linda J ^c   Schoch, Guillaume A ^a   Gileadi, Carina ^a   Fedorov, Oleg Y ^a   Dowler, Elizabeth F ^c   Higman, Victoria A ^c   Hutsell, Stephanie Q ^b   Sundström, Michael ^a,d   Doyle, Declan A ^a,e   Siderovski, David P ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^d University of Copenhagen   (Denmark)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

GTPase accelerating proteins; NMR structure; RGS proteins; x ray crystallography

Indexed keywords

HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SUBUNIT; RGS PROTEIN; APOPROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT;

ARTICLE; COMPLEX FORMATION; ENZYME SPECIFICITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

APOPROTEINS; GTP-BINDING PROTEIN ALPHA SUBUNITS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RGS PROTEINS;

EID: 44049098168     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0801508105     Document Type: Article

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