A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protein-mediated kinetic scaffolding

Journal of Biological Chemistry

Volumn 278, Issue 9, 2003, Pages 7278-7284

  Zhong, Hailing ^a   Wade, Susan M ^a   Woolf, Peter J ^b   Linderman, Jennifer J ^b   Traynor, John R ^a   Neubig, Richard R ^a,b,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SIGNALS;

COMPUTER SIMULATION; HYDROLYSIS; MATHEMATICAL MODELS; MONTE CARLO METHODS;

PROTEINS;

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); RECEPTOR; RGS PROTEIN; GLUTATHIONE TRANSFERASE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; HYBRID PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HYDROLYSIS; KINETICS; MOLECULAR MODEL; MONTE CARLO METHOD; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; CHO CELL; DOSE RESPONSE; HAMSTER; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TIME;

ANIMALIA;

ANIMALS; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE TRANSFERASE; GTP PHOSPHOHYDROLASES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYDROLYSIS; KINETICS; MONTE CARLO METHOD; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RGS PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 0037470041     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208819200     Document Type: Article

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