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Volumn 266, Issue 2, 2009, Pages 161-170

The Stem Cell Network model: Clinical implications in cancer

Author keywords

Cancer stem cells; Carcinogenesis; Field cancerization; Head and neck squamous cell carcinomas; Screening

Indexed keywords

BREAST CARCINOMA; CANCER GROWTH; CANCER RECURRENCE; CANCER STEM CELL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL FATE; CELL SHAPE; CELL SIZE; EMBRYONIC STEM CELL; HEAD AND NECK CARCINOMA; HUMAN; METASTASIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOMATIC CELL; STEM CELL;

EID: 57649222067     PISSN: 09374477     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00405-008-0809-3     Document Type: Review
Times cited : (19)

References (103)
  • 1
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: An old idea-a paradigm shift
    • 10.1158/0008-5472.CAN-05-3153 Discussion 1895-1896
    • MS Wicha S Liu G Dontu 2006 Cancer stem cells: an old idea-a paradigm shift Cancer Res 66 1883 1890 10.1158/0008-5472.CAN-05-3153 Discussion 1895-1896
    • (2006) Cancer Res , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 2
    • 16844378799 scopus 로고    scopus 로고
    • Leukaemia stem cells and the evolution of cancer-stem-cell research
    • 10.1038/nrc1592
    • BJ Huntly DG Gilliland 2005 Leukaemia stem cells and the evolution of cancer-stem-cell research Nat Rev Cancer 5 311 321 10.1038/nrc1592
    • (2005) Nat Rev Cancer , vol.5 , pp. 311-321
    • Huntly, B.J.1    Gilliland, D.G.2
  • 3
    • 0002740313 scopus 로고
    • A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo
    • 10.1038/199079a0
    • WR Bruce H Van Der Gaag 1963 A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo Nature 199 79 80 10.1038/199079a0
    • (1963) Nature , vol.199 , pp. 79-80
    • Bruce, W.R.1    Van Der Gaag, H.2
  • 4
  • 5
    • 0017785769 scopus 로고
    • Primary bioassay of human tumor stem cells
    • 10.1126/science.560061
    • AW Hamburger SE Salmon 1977 Primary bioassay of human tumor stem cells Science 197 461 463 10.1126/science.560061
    • (1977) Science , vol.197 , pp. 461-463
    • Hamburger, A.W.1    Salmon, S.E.2
  • 6
    • 34447623574 scopus 로고    scopus 로고
    • The hunt for cancer-initiating cells: A history stemming from leukemia
    • 8
    • MP Buzzeo EW Scott CR Cogle 2007 The hunt for cancer-initiating cells: a history stemming from leukemia Leukemia 21 8 1619 1627
    • (2007) Leukemia , vol.21 , pp. 1619-1627
    • Buzzeo, M.P.1    Scott, E.W.2    Cogle, C.R.3
  • 7
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • 10.1038/35102167
    • T Reya SJ Morrison MF Clarke IL Weissman 2001 Stem cells, cancer, and cancer stem cells Nature 414 105 111 10.1038/35102167
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 8
    • 33644559031 scopus 로고    scopus 로고
    • Identifying cancer stem cells in solid tumors: Case not proven
    • 10.1158/0008-5472.CAN-05-3450 Discussion 1890
    • RP Hill 2006 Identifying cancer stem cells in solid tumors: case not proven Cancer Res 66 1891 1895 10.1158/0008-5472.CAN-05-3450 Discussion 1890
    • (2006) Cancer Res , vol.66 , pp. 1891-1895
    • Hill, R.P.1
  • 9
    • 33644520922 scopus 로고    scopus 로고
    • Target for cancer therapy: Proliferating cells or stem cells
    • 10.1038/sj.leu.2404075
    • MV Blagosklonny 2006 Target for cancer therapy: proliferating cells or stem cells Leukemia 20 385 391 10.1038/sj.leu.2404075
    • (2006) Leukemia , vol.20 , pp. 385-391
    • Blagosklonny, M.V.1
  • 10
    • 33750584024 scopus 로고    scopus 로고
    • Tumour stem cell-targeted treatment: Elimination or differentiation
    • 10.1093/annonc/mdl074
    • C Massard E Deutsch JC Soria 2006 Tumour stem cell-targeted treatment: elimination or differentiation Ann Oncol 17 1620 1624 10.1093/annonc/mdl074
    • (2006) Ann Oncol , vol.17 , pp. 1620-1624
    • Massard, C.1    Deutsch, E.2    Soria, J.C.3
  • 11
    • 1642603951 scopus 로고    scopus 로고
    • Socializing with the neighbors: Stem cells and their niche
    • 10.1016/S0092-8674(04)00255-7
    • E Fuchs T Tumbar G Guasch 2004 Socializing with the neighbors: stem cells and their niche Cell 116 769 778 10.1016/S0092-8674(04)00255-7
    • (2004) Cell , vol.116 , pp. 769-778
    • Fuchs, E.1    Tumbar, T.2    Guasch, G.3
  • 12
    • 33745635043 scopus 로고    scopus 로고
    • The stem-cell niche as an entity of action
    • 10.1038/nature04957
    • DT Scadden 2006 The stem-cell niche as an entity of action Nature 441 1075 1079 10.1038/nature04957
    • (2006) Nature , vol.441 , pp. 1075-1079
    • Scadden, D.T.1
  • 13
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • 10.1038/367645a0
    • T Lapidot C Sirard J Vormoor 1994 A cell initiating human acute myeloid leukaemia after transplantation into SCID mice Nature 367 645 648 10.1038/367645a0
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 15
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • 10.1038/nature03128
    • SK Singh C Hawkins ID Clarke 2004 Identification of human brain tumour initiating cells Nature 432 396 401 10.1038/nature03128
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 16
    • 33644825465 scopus 로고    scopus 로고
    • Stem-like cells in bone sarcomas: Implications for tumorigenesis
    • 10.1593/neo.05394
    • CP Gibbs VG Kukekov JD Reith 2005 Stem-like cells in bone sarcomas: implications for tumorigenesis Neoplasia 7 967 976 10.1593/neo.05394
    • (2005) Neoplasia , vol.7 , pp. 967-976
    • Gibbs, C.P.1    Kukekov, V.G.2    Reith, J.D.3
  • 17
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • 10.1038/nature05372
    • CA O'Brien A Pollett S Gallinger JE Dick 2007 A human colon cancer cell capable of initiating tumour growth in immunodeficient mice Nature 445 106 110 10.1038/nature05372
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 18
    • 33847052127 scopus 로고    scopus 로고
    • Identification of pancreatic cancer stem cells
    • 10.1158/0008-5472.CAN-06-2030
    • C Li DG Heidt P Dalerba 2007 Identification of pancreatic cancer stem cells Cancer Res 67 1030 1037 10.1158/0008-5472.CAN-06-2030
    • (2007) Cancer Res , vol.67 , pp. 1030-1037
    • Li, C.1    Heidt, D.G.2    Dalerba, P.3
  • 19
    • 31944448885 scopus 로고    scopus 로고
    • Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation
    • 10.1073/pnas.0510652103
    • S Wang AJ Garcia M Wu DA Lawson ON Witte H Wu 2006 Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation Proc Natl Acad Sci USA 103 1480 1485 10.1073/pnas.0510652103
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 1480-1485
    • Wang, S.1    Garcia, A.J.2    Wu, M.3    Lawson, D.A.4    Witte, O.N.5    Wu, H.6
  • 20
    • 33846512398 scopus 로고    scopus 로고
    • Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
    • 10.1073/pnas.0610117104
    • ME Prince R Sivanandan A Kaczorowski 2007 Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma Proc Natl Acad Sci USA 104 973 978 10.1073/pnas. 0610117104
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 973-978
    • Prince, M.E.1    Sivanandan, R.2    Kaczorowski, A.3
  • 21
    • 39449135834 scopus 로고    scopus 로고
    • PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
    • 10.1101/gad.1627008
    • D Hambardzumyan OJ Becher MK Rosenblum PP Pandolfi K Manova-Todorova EC Holland 2008 PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo Genes Dev 22 436 448 10.1101/gad.1627008
    • (2008) Genes Dev , vol.22 , pp. 436-448
    • Hambardzumyan, D.1    Becher, O.J.2    Rosenblum, M.K.3    Pandolfi, P.P.4    Manova-Todorova, K.5    Holland, E.C.6
  • 22
    • 34547193404 scopus 로고    scopus 로고
    • Phenotypic characterization of human colorectal cancer stem cells
    • 4
    • P Dalerba SJ Dylla IK Park 2007 Phenotypic characterization of human colorectal cancer stem cells Proc Natl Acad Sci USA 134 4 10158 10163
    • (2007) Proc Natl Acad Sci USA , vol.134 , pp. 10158-10163
    • Dalerba, P.1    Dylla, S.J.2    Park, I.K.3
  • 23
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • 10.1038/nrc1232
    • R Pardal MF Clarke SJ Morrison 2003 Applying the principles of stem-cell biology to cancer Nat Rev Cancer 3 895 902 10.1038/nrc1232
    • (2003) Nat Rev Cancer , vol.3 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 24
    • 33751210076 scopus 로고    scopus 로고
    • The cancer stem cell hypothesis: A work in progress
    • 10.1038/labinvest.3700488
    • BT Tan CY Park LE Ailles IL Weissman 2006 The cancer stem cell hypothesis: a work in progress Lab Invest 86 1203 1207 10.1038/labinvest.3700488
    • (2006) Lab Invest , vol.86 , pp. 1203-1207
    • Tan, B.T.1    Park, C.Y.2    Ailles, L.E.3    Weissman, I.L.4
  • 25
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • 10.1038/nm0797-730
    • D Bonnet JE Dick 1997 Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell Nat Med 3 730 737 10.1038/nm0797-730
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 26
    • 17944376561 scopus 로고    scopus 로고
    • AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations
    • 10.1073/pnas.171321298
    • Y Yuan L Zhou T Miyamoto 2001 AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations Proc Natl Acad Sci USA 98 10398 10403 10.1073/pnas.171321298
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10398-10403
    • Yuan, Y.1    Zhou, L.2    Miyamoto, T.3
  • 27
    • 34250822389 scopus 로고    scopus 로고
    • Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts
    • 12
    • Z Zhou A Flesken-Nikitin AY Nikitin 2007 Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts Cancer Res 67 12 5683 5690
    • (2007) Cancer Res , vol.67 , pp. 5683-5690
    • Zhou, Z.1    Flesken-Nikitin, A.2    Nikitin, A.Y.3
  • 28
    • 18744377702 scopus 로고    scopus 로고
    • The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis
    • 10.1073/pnas.0502320102
    • L Xin DA Lawson ON Witte 2005 The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis Proc Natl Acad Sci USA 102 6942 6947 10.1073/pnas.0502320102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 6942-6947
    • Xin, L.1    Lawson, D.A.2    Witte, O.N.3
  • 29
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • 10.1038/nature06534
    • IH Park R Zhao JA West 2008 Reprogramming of human somatic cells to pluripotency with defined factors Nature 451 141 146 10.1038/nature06534
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3
  • 30
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • 10.1126/science.1151526
    • J Yu MA Vodyanik K Smuga-Otto 2007 Induced pluripotent stem cell lines derived from human somatic cells Science 318 1917 1920 10.1126/science.1151526
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 31
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • 10.1016/j.cell.2007.11.019
    • K Takahashi K Tanabe M Ohnuki 2007 Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 861 872 10.1016/j.cell.2007.11.019
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 32
    • 41449118521 scopus 로고    scopus 로고
    • Module map of stem cell genes guides creation of epithelial cancer stem cells
    • 10.1016/j.stem.2008.02.009
    • DJ Wong H Liu TW Ridky D Cassarino E Segal HY Chang 2008 Module map of stem cell genes guides creation of epithelial cancer stem cells Cell Stem Cell 2 333 344 10.1016/j.stem.2008.02.009
    • (2008) Cell Stem Cell , vol.2 , pp. 333-344
    • Wong, D.J.1    Liu, H.2    Ridky, T.W.3    Cassarino, D.4    Segal, E.5    Chang, H.Y.6
  • 33
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; Clinical implications of multicentric origin
    • 10.1002/1097-0142(195309)6:5<963::AID-CNCR2820060515>3.0.CO;2-Q
    • DP Slaughter HW Southwick W Smejkal 1953 Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin Cancer 6 963 968 10.1002/1097-0142(195309)6:5<963::AID-CNCR2820060515>3.0. CO;2-Q
    • (1953) Cancer , vol.6 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 34
    • 2542584017 scopus 로고    scopus 로고
    • Genetically altered fields as origin of locally recurrent head and neck cancer: A retrospective study
    • 10.1158/1078-0432.CCR-03-0632
    • MP Tabor RH Brakenhoff HJ Ruijter-Schippers JA Kummer CR Leemans BJ Braakhuis 2004 Genetically altered fields as origin of locally recurrent head and neck cancer: a retrospective study Clin Cancer Res 10 3607 3613 10.1158/1078-0432.CCR-03-0632
    • (2004) Clin Cancer Res , vol.10 , pp. 3607-3613
    • Tabor, M.P.1    Brakenhoff, R.H.2    Ruijter-Schippers, H.J.3    Kummer, J.A.4    Leemans, C.R.5    Braakhuis, B.J.6
  • 35
    • 33846662128 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer
    • 10.1186/1476-4598-5-73
    • G Sui S Zhou J Wang 2006 Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer Mol Cancer 5 73 10.1186/1476-4598-5-73
    • (2006) Mol Cancer , vol.5 , pp. 73
    • Sui, G.1    Zhou, S.2    Wang, J.3
  • 36
    • 25144518262 scopus 로고    scopus 로고
    • MGMT promoter methylation and field defect in sporadic colorectal cancer
    • L Shen Y Kondo GL Rosner 2005 MGMT promoter methylation and field defect in sporadic colorectal cancer J Natl Cancer Inst 97 1330 1338
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1330-1338
    • Shen, L.1    Kondo, Y.2    Rosner, G.L.3
  • 37
    • 0030461224 scopus 로고    scopus 로고
    • Loss of heterozygosity in normal tissue adjacent to breast carcinomas
    • 10.1126/science.274.5295.2057
    • G Deng Y Lu G Zlotnikov AD Thor HS Smith 1996 Loss of heterozygosity in normal tissue adjacent to breast carcinomas Science 274 2057 2059 10.1126/science.274.5295.2057
    • (1996) Science , vol.274 , pp. 2057-2059
    • Deng, G.1    Lu, Y.2    Zlotnikov, G.3    Thor, A.D.4    Smith, H.S.5
  • 38
    • 33646504142 scopus 로고    scopus 로고
    • Telomere DNA content and allelic imbalance demonstrate field cancerization in histologically normal tissue adjacent to breast tumors
    • 10.1002/ijc.21815
    • CM Heaphy M Bisoffi CA Fordyce 2006 Telomere DNA content and allelic imbalance demonstrate field cancerization in histologically normal tissue adjacent to breast tumors Int J Cancer 119 108 116 10.1002/ijc.21815
    • (2006) Int J Cancer , vol.119 , pp. 108-116
    • Heaphy, C.M.1    Bisoffi, M.2    Fordyce, C.A.3
  • 39
    • 0035992381 scopus 로고    scopus 로고
    • Mitochondrial C-tract alteration in premalignant lesions of the head and neck: A marker for progression and clonal proliferation
    • PK Ha BC Tong WH Westra 2002 Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation Clin Cancer Res 8 2260 2265
    • (2002) Clin Cancer Res , vol.8 , pp. 2260-2265
    • Ha, P.K.1    Tong, B.C.2    Westra, W.H.3
  • 40
    • 26844467247 scopus 로고    scopus 로고
    • Differences in gene expression in prostate cancer, normal appearing prostate tissue adjacent to cancer and prostate tissue from cancer free organ donors
    • 10.1186/1471-2407-5-45
    • UR Chandran R Dhir C Ma G Michalopoulos M Becich J Gilbertson 2005 Differences in gene expression in prostate cancer, normal appearing prostate tissue adjacent to cancer and prostate tissue from cancer free organ donors BMC Cancer 5 45 10.1186/1471-2407-5-45
    • (2005) BMC Cancer , vol.5 , pp. 45
    • Chandran, U.R.1    Dhir, R.2    Ma, C.3    Michalopoulos, G.4    Becich, M.5    Gilbertson, J.6
  • 41
    • 0037446974 scopus 로고    scopus 로고
    • A genetic explanation of Slaughter's concept of field cancerization: Evidence and clinical implications
    • BJ Braakhuis MP Tabor JA Kummer CR Leemans RH Brakenhoff 2003 A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications Cancer Res 63 1727 1730
    • (2003) Cancer Res , vol.63 , pp. 1727-1730
    • Braakhuis, B.J.1    Tabor, M.P.2    Kummer, J.A.3    Leemans, C.R.4    Brakenhoff, R.H.5
  • 42
    • 0345130005 scopus 로고    scopus 로고
    • Field cancerization, clonality, and epithelial stem cells: The spread of mutated clones in epithelial sheets
    • 10.1002/(SICI)1096-9896(199901)187:1<61::AID-PATH247>3.0.CO;2-I
    • SB Garcia HS Park M Novelli NA Wright 1999 Field cancerization, clonality, and epithelial stem cells: the spread of mutated clones in epithelial sheets J Pathol 187 61 81 10.1002/(SICI)1096-9896(199901)187:1<61::AID- PATH247>3.0.CO;2-I
    • (1999) J Pathol , vol.187 , pp. 61-81
    • Garcia, S.B.1    Park, H.S.2    Novelli, M.3    Wright, N.A.4
  • 43
    • 0034908506 scopus 로고    scopus 로고
    • Persistence of genetically altered fields in head and neck cancer patients: Biological and clinical implications
    • MP Tabor RH Brakenhoff VM van Houten 2001 Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications Clin Cancer Res 7 1523 1532
    • (2001) Clin Cancer Res , vol.7 , pp. 1523-1532
    • Tabor, M.P.1    Brakenhoff, R.H.2    Van Houten, V.M.3
  • 44
    • 33846038402 scopus 로고    scopus 로고
    • Proteomic analysis reveals successive aberrations in protein expression from healthy mucosa to invasive head and neck cancer
    • 10.1038/sj.onc.1209770
    • M Roesch-Ely M Nees S Karsai 2007 Proteomic analysis reveals successive aberrations in protein expression from healthy mucosa to invasive head and neck cancer Oncogene 26 54 64 10.1038/sj.onc.1209770
    • (2007) Oncogene , vol.26 , pp. 54-64
    • Roesch-Ely, M.1    Nees, M.2    Karsai, S.3
  • 45
    • 0035890616 scopus 로고    scopus 로고
    • P16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium
    • DJ Wong TG Paulson LJ Prevo 2001 p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium Cancer Res 61 8284 8289
    • (2001) Cancer Res , vol.61 , pp. 8284-8289
    • Wong, D.J.1    Paulson, T.G.2    Prevo, L.J.3
  • 46
    • 33748589460 scopus 로고    scopus 로고
    • The epigenetic silencing of LIMS2 in gastric cancer and its inhibitory effect on cell migration
    • 10.1016/j.bbrc.2006.08.128
    • SK Kim HR Jang JH Kim 2006 The epigenetic silencing of LIMS2 in gastric cancer and its inhibitory effect on cell migration Biochem Biophys Res Commun 349 1032 1040 10.1016/j.bbrc.2006.08.128
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 1032-1040
    • Kim, S.K.1    Jang, H.R.2    Kim, J.H.3
  • 47
    • 1042278719 scopus 로고    scopus 로고
    • Mitochondrial DNA mutation at the D310 (displacement loop) mononucleotide sequence in the pathogenesis of gallbladder carcinoma
    • 10.1158/1078-0432.CCR-0701-3
    • M Tang S Baez M Pruyas 2004 Mitochondrial DNA mutation at the D310 (displacement loop) mononucleotide sequence in the pathogenesis of gallbladder carcinoma Clin Cancer Res 10 1041 1046 10.1158/1078-0432.CCR-0701-3
    • (2004) Clin Cancer Res , vol.10 , pp. 1041-1046
    • Tang, M.1    Baez, S.2    Pruyas, M.3
  • 48
    • 0037434419 scopus 로고    scopus 로고
    • Mitochondrial DNA damage in non-melanoma skin cancer
    • 10.1038/sj.bjc.6600773
    • SE Durham KJ Krishnan J Betts MA Birch-Machin 2003 Mitochondrial DNA damage in non-melanoma skin cancer Br J Cancer 88 90 95 10.1038/sj.bjc.6600773
    • (2003) Br J Cancer , vol.88 , pp. 90-95
    • Durham, S.E.1    Krishnan, K.J.2    Betts, J.3    Birch-Machin, M.A.4
  • 49
    • 0032927128 scopus 로고    scopus 로고
    • Monoclonality and surface lesion-specific microsatellite alterations in premalignant and malignant neoplasia of uterine cervix: A local field effect of genomic instability and clonal evolution
    • 10.1002/(SICI)1098-2264(199902)24:2<127::AID-GCC5>3.0.CO;2-8
    • TY Chu CY Shen HS Lee HS Liu 1999 Monoclonality and surface lesion-specific microsatellite alterations in premalignant and malignant neoplasia of uterine cervix: a local field effect of genomic instability and clonal evolution Genes Chromosomes Cancer 24 127 134 10.1002/(SICI)1098- 2264(199902)24:2<127::AID-GCC5>3.0.CO;2-8
    • (1999) Genes Chromosomes Cancer , vol.24 , pp. 127-134
    • Chu, T.Y.1    Shen, C.Y.2    Lee, H.S.3    Liu, H.S.4
  • 50
    • 0036605097 scopus 로고    scopus 로고
    • Molecular evidence of a common clonal origin and subsequent divergent clonal evolution in vulval intraepithelial neoplasia, vulval squamous cell carcinoma and lymph node metastases
    • 10.1002/ijc.10362
    • AN Rosenthal A Ryan D Hopster IJ Jacobs 2002 Molecular evidence of a common clonal origin and subsequent divergent clonal evolution in vulval intraepithelial neoplasia, vulval squamous cell carcinoma and lymph node metastases Int J Cancer 99 549 554 10.1002/ijc.10362
    • (2002) Int J Cancer , vol.99 , pp. 549-554
    • Rosenthal, A.N.1    Ryan, A.2    Hopster, D.3    Jacobs, I.J.4
  • 51
    • 33746597351 scopus 로고    scopus 로고
    • Development and progression of urothelial carcinoma
    • 10.1111/j.1349-7006.2006.00264.x
    • T Kakizoe 2006 Development and progression of urothelial carcinoma Cancer Sci 97 821 828 10.1111/j.1349-7006.2006.00264.x
    • (2006) Cancer Sci , vol.97 , pp. 821-828
    • Kakizoe, T.1
  • 52
    • 33644697320 scopus 로고    scopus 로고
    • Deletions at chromosome 2q and 12p are early and frequent molecular alterations in bronchial epithelium and NSCLC of long-term smokers
    • U Grepmeier W Dietmaier J Merk 2005 Deletions at chromosome 2q and 12p are early and frequent molecular alterations in bronchial epithelium and NSCLC of long-term smokers Int J Oncol 27 481 488
    • (2005) Int J Oncol , vol.27 , pp. 481-488
    • Grepmeier, U.1    Dietmaier, W.2    Merk, J.3
  • 53
    • 33745199586 scopus 로고    scopus 로고
    • The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas
    • 10.1158/1078-0432.CCR-05-2679
    • D Furlan I Carnevali B Marcomini 2006 The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas Clin Cancer Res 12 3329 3336 10.1158/1078-0432.CCR-05-2679
    • (2006) Clin Cancer Res , vol.12 , pp. 3329-3336
    • Furlan, D.1    Carnevali, I.2    Marcomini, B.3
  • 54
    • 2342544035 scopus 로고    scopus 로고
    • Comparison of K-ras point mutation distributions in intraductal papillary-mucinous tumors and ductal adenocarcinoma of the pancreas
    • 10.1002/ijc.20084
    • M Kitago M Ueda K Aiura 2004 Comparison of K-ras point mutation distributions in intraductal papillary-mucinous tumors and ductal adenocarcinoma of the pancreas Int J Cancer 110 177 182 10.1002/ijc.20084
    • (2004) Int J Cancer , vol.110 , pp. 177-182
    • Kitago, M.1    Ueda, M.2    Aiura, K.3
  • 55
    • 33144465069 scopus 로고    scopus 로고
    • Gene promoter methylation in prostate tumor-associated stromal cells
    • JA Hanson JW Gillespie A Grover 2006 Gene promoter methylation in prostate tumor-associated stromal cells J Natl Cancer Inst 98 255 261
    • (2006) J Natl Cancer Inst , vol.98 , pp. 255-261
    • Hanson, J.A.1    Gillespie, J.W.2    Grover, A.3
  • 56
    • 0036714889 scopus 로고    scopus 로고
    • Genetic aberrations in gliomatosis cerebri support monoclonal tumorigenesis
    • JM Kros P Zheng WN Dinjens JC Alers 2002 Genetic aberrations in gliomatosis cerebri support monoclonal tumorigenesis J Neuropathol Exp Neurol 61 806 814
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 806-814
    • Kros, J.M.1    Zheng, P.2    Dinjens, W.N.3    Alers, J.C.4
  • 57
    • 6344223516 scopus 로고    scopus 로고
    • Riddle: What do aplastic anemia, acute promyelocytic leukemia, and chronic myeloid leukemia have in common?
    • 10.1038/sj.leu.2403487
    • RA Brodsky RJ Jones 2004 Riddle: what do aplastic anemia, acute promyelocytic leukemia, and chronic myeloid leukemia have in common? Leukemia 18 1740 1742 10.1038/sj.leu.2403487
    • (2004) Leukemia , vol.18 , pp. 1740-1742
    • Brodsky, R.A.1    Jones, R.J.2
  • 58
    • 0033047022 scopus 로고    scopus 로고
    • Homing and mobilization in the stem cell niche
    • 10.1016/S0962-8924(99)01559-7
    • AD Whetton GJ Graham 1999 Homing and mobilization in the stem cell niche Trends Cell Biol 9 233 238 10.1016/S0962-8924(99)01559-7
    • (1999) Trends Cell Biol , vol.9 , pp. 233-238
    • Whetton, A.D.1    Graham, G.J.2
  • 59
    • 9444265320 scopus 로고    scopus 로고
    • Gastric cancer originating from bone marrow-derived cells
    • 10.1126/science.1099513
    • J Houghton C Stoicov S Nomura 2004 Gastric cancer originating from bone marrow-derived cells Science 306 1568 1571 10.1126/science.1099513
    • (2004) Science , vol.306 , pp. 1568-1571
    • Houghton, J.1    Stoicov, C.2    Nomura, S.3
  • 60
    • 40349098612 scopus 로고    scopus 로고
    • Migratory neighbors and distant invaders: Tumor-associated niche cells
    • 10.1101/gad.1636908
    • J Wels RN Kaplan S Rafii D Lyden 2008 Migratory neighbors and distant invaders: tumor-associated niche cells Genes Dev 22 559 574 10.1101/gad.1636908
    • (2008) Genes Dev , vol.22 , pp. 559-574
    • Wels, J.1    Kaplan, R.N.2    Rafii, S.3    Lyden, D.4
  • 61
    • 25444495269 scopus 로고    scopus 로고
    • Opinion: Migrating cancer stem cells-an integrated concept of malignant tumour progression
    • 10.1038/nrc1694
    • T Brabletz A Jung S Spaderna F Hlubek T Kirchner 2005 Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression Nat Rev Cancer 5 744 749 10.1038/nrc1694
    • (2005) Nat Rev Cancer , vol.5 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 62
    • 0344845003 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and pathologies
    • 10.1016/j.ceb.2003.10.006
    • JP Thiery 2003 Epithelial-mesenchymal transitions in development and pathologies Curr Opin Cell Biol 15 740 746 10.1016/j.ceb.2003.10.006
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 740-746
    • Thiery, J.P.1
  • 63
    • 34547098824 scopus 로고    scopus 로고
    • Mosaic organization of neural stem cells in the adult brain
    • 5836
    • FT Merkle Z Mirzadeh A Alvarez-Buylla 2007 Mosaic organization of neural stem cells in the adult brain Science 317 5836 381 384
    • (2007) Science , vol.317 , pp. 381-384
    • Merkle, F.T.1    Mirzadeh, Z.2    Alvarez-Buylla, A.3
  • 64
    • 0037158692 scopus 로고    scopus 로고
    • A progression puzzle
    • 10.1038/418823a
    • R Bernards RA Weinberg 2002 A progression puzzle Nature 418 823 10.1038/418823a
    • (2002) Nature , vol.418 , pp. 823
    • Bernards, R.1    Weinberg, R.A.2
  • 66
    • 33748341688 scopus 로고    scopus 로고
    • Laryngeal cancer in the United States: Changes in demographics, patterns of care, and survival
    • 10.1097/01.mlg.0000236095.97947.26
    • HT Hoffman K Porter LH Karnell 2006 Laryngeal cancer in the United States: changes in demographics, patterns of care, and survival Laryngoscope 116 1 13 10.1097/01.mlg.0000236095.97947.26
    • (2006) Laryngoscope , vol.116 , pp. 1-13
    • Hoffman, H.T.1    Porter, K.2    Karnell, L.H.3
  • 67
    • 33847653707 scopus 로고    scopus 로고
    • The chemoradiation paradigm in head and neck cancer
    • 10.1038/ncponc0750
    • TY Seiwert JK Salama EE Vokes 2007 The chemoradiation paradigm in head and neck cancer Nat Clin Pract Oncol 4 156 171 10.1038/ncponc0750
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 156-171
    • Seiwert, T.Y.1    Salama, J.K.2    Vokes, E.E.3
  • 68
    • 0028814029 scopus 로고
    • Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck
    • 10.1056/NEJM199502163320704
    • JA Brennan L Mao RH Hruban 1995 Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck N Engl J Med 332 429 435 10.1056/NEJM199502163320704
    • (1995) N Engl J Med , vol.332 , pp. 429-435
    • Brennan, J.A.1    Mao, L.2    Hruban, R.H.3
  • 69
    • 0036899257 scopus 로고    scopus 로고
    • Mutated p53 as a molecular marker for the diagnosis of head and neck cancer
    • 10.1002/path.1242
    • VM van Houten MP Tabor MW van den Brekel 2002 Mutated p53 as a molecular marker for the diagnosis of head and neck cancer J Pathol 198 476 486 10.1002/path.1242
    • (2002) J Pathol , vol.198 , pp. 476-486
    • Van Houten, V.M.1    Tabor, M.P.2    Van Den Brekel, M.W.3
  • 70
    • 0032765874 scopus 로고    scopus 로고
    • Second esophageal tumors in patients with head and neck squamous cell carcinoma: An assessment of clonal relationships
    • J Califano PL Leong WM Koch CF Eisenberger D Sidransky WH Westra 1999 Second esophageal tumors in patients with head and neck squamous cell carcinoma: an assessment of clonal relationships Clin Cancer Res 5 1862 1867
    • (1999) Clin Cancer Res , vol.5 , pp. 1862-1867
    • Califano, J.1    Leong, P.L.2    Koch, W.M.3    Eisenberger, C.F.4    Sidransky, D.5    Westra, W.H.6
  • 71
    • 0036141366 scopus 로고    scopus 로고
    • Discordance of genetic alterations between primary head and neck tumors and corresponding metastases associated with mutational status of the TP53 gene
    • 10.1002/gcc.10019
    • MP Tabor VM van Houten JA Kummer 2002 Discordance of genetic alterations between primary head and neck tumors and corresponding metastases associated with mutational status of the TP53 gene Genes Chromosomes Cancer 33 168 177 10.1002/gcc.10019
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 168-177
    • Tabor, M.P.1    Van Houten, V.M.2    Kummer, J.A.3
  • 72
    • 33846959831 scopus 로고    scopus 로고
    • Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissues
    • 10.1007/s00418-006-0251-9
    • HB Zhang CP Ren XY Yang 2007 Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissues Histochem Cell Biol 127 347 354 10.1007/s00418-006-0251-9
    • (2007) Histochem Cell Biol , vol.127 , pp. 347-354
    • Zhang, H.B.1    Ren, C.P.2    Yang, X.Y.3
  • 73
    • 0032709289 scopus 로고    scopus 로고
    • Mapping dynamic epithelial cell proliferative activity within the oral cavity of man: A new insight into carcinogenesis?
    • 10.1054/bjom.1999.0130
    • PJ Thomson CS Potten DR Appleton 1999 Mapping dynamic epithelial cell proliferative activity within the oral cavity of man: a new insight into carcinogenesis? Br J Oral Maxillofac Surg 37 377 383 10.1054/bjom.1999.0130
    • (1999) Br J Oral Maxillofac Surg , vol.37 , pp. 377-383
    • Thomson, P.J.1    Potten, C.S.2    Appleton, D.R.3
  • 74
  • 75
    • 0030750372 scopus 로고    scopus 로고
    • Combined surgery and radiation therapy for squamous cell carcinoma of the hypopharynx
    • 10.1016/S0194-5998(97)70240-7
    • DH Kraus MJ Zelefsky HA Brock J Huo LB Harrison JP Shah 1997 Combined surgery and radiation therapy for squamous cell carcinoma of the hypopharynx Otolaryngol Head Neck Surg 116 637 641 10.1016/S0194-5998(97)70240-7
    • (1997) Otolaryngol Head Neck Surg , vol.116 , pp. 637-641
    • Kraus, D.H.1    Zelefsky, M.J.2    Brock, H.A.3    Huo, J.4    Harrison, L.B.5    Shah, J.P.6
  • 76
    • 0036157447 scopus 로고    scopus 로고
    • Second primary tumors and field cancerization in oral and oropharyngeal cancer: Molecular techniques provide new insights and definitions
    • 10.1002/hed.10042
    • BJ Braakhuis MP Tabor CR Leemans I van der Waal GB Snow RH Brakenhoff 2002 Second primary tumors and field cancerization in oral and oropharyngeal cancer: molecular techniques provide new insights and definitions Head Neck 24 198 206 10.1002/hed.10042
    • (2002) Head Neck , vol.24 , pp. 198-206
    • Braakhuis, B.J.1    Tabor, M.P.2    Leemans, C.R.3    Van Der Waal, I.4    Snow, G.B.5    Brakenhoff, R.H.6
  • 77
    • 33845489461 scopus 로고    scopus 로고
    • Surgery and postoperative radiotherapy for squamous cell carcinoma of the larynx and pharynx
    • 10.1097/01.coc.0000242319.09994.78
    • RW Hinerman CG Morris RJ Amdur 2006 Surgery and postoperative radiotherapy for squamous cell carcinoma of the larynx and pharynx Am J Clin Oncol 29 613 621 10.1097/01.coc.0000242319.09994.78
    • (2006) Am J Clin Oncol , vol.29 , pp. 613-621
    • Hinerman, R.W.1    Morris, C.G.2    Amdur, R.J.3
  • 78
    • 0036367605 scopus 로고    scopus 로고
    • Cell kinetic studies in the murine ventral tongue epithelium: Thymidine metabolism studies and circadian rhythm determination
    • Suppl 1. 10.1046/j.1365-2184.35.s1.1.x
    • CS Potten D Booth NJ Cragg 2002 Cell kinetic studies in the murine ventral tongue epithelium: thymidine metabolism studies and circadian rhythm determination Cell Prolif 35 Suppl 1 1 15 10.1046/j.1365-2184.35.s1.1.x
    • (2002) Cell Prolif , vol.35 , pp. 1-15
    • Potten, C.S.1    Booth, D.2    Cragg, N.J.3
  • 80
    • 0036347157 scopus 로고    scopus 로고
    • Oral cancer and precancerous lesions
    • BW Neville TA Day 2002 Oral cancer and precancerous lesions CA Cancer J Clin 52 195 215
    • (2002) CA Cancer J Clin , vol.52 , pp. 195-215
    • Neville, B.W.1    Day, T.A.2
  • 83
    • 33846857321 scopus 로고    scopus 로고
    • VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
    • 10.1182/blood-2006-05-021758
    • S Hirakawa LF Brown S Kodama K Paavonen K Alitalo M Detmar 2007 VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites Blood 109 1010 1017 10.1182/blood-2006-05-021758
    • (2007) Blood , vol.109 , pp. 1010-1017
    • Hirakawa, S.1    Brown, L.F.2    Kodama, S.3    Paavonen, K.4    Alitalo, K.5    Detmar, M.6
  • 84
    • 19344364684 scopus 로고    scopus 로고
    • Hematopoietic cells maintain hematopoietic fates upon entering the brain
    • 10.1084/jem.20050030
    • M Massengale AJ Wagers H Vogel IL Weissman 2005 Hematopoietic cells maintain hematopoietic fates upon entering the brain J Exp Med 201 1579 1589 10.1084/jem.20050030
    • (2005) J Exp Med , vol.201 , pp. 1579-1589
    • Massengale, M.1    Wagers, A.J.2    Vogel, H.3    Weissman, I.L.4
  • 85
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • 10.1126/science.1074807
    • AJ Wagers RI Sherwood JL Christensen IL Weissman 2002 Little evidence for developmental plasticity of adult hematopoietic stem cells Science 297 2256 2259 10.1126/science.1074807
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.I.2    Christensen, J.L.3    Weissman, I.L.4
  • 86
    • 0030582344 scopus 로고    scopus 로고
    • Clonal analysis of isolated single fundic and pyloric gland of stomach using X-linked polymorphism
    • 10.1006/bbrc.1996.1365
    • S Nomura M Kaminishi K Sugiyama T Oohara H Esumi 1996 Clonal analysis of isolated single fundic and pyloric gland of stomach using X-linked polymorphism Biochem Biophys Res Commun 226 385 390 10.1006/bbrc.1996.1365
    • (1996) Biochem Biophys Res Commun , vol.226 , pp. 385-390
    • Nomura, S.1    Kaminishi, M.2    Sugiyama, K.3    Oohara, T.4    Esumi, H.5
  • 87
    • 0029684011 scopus 로고    scopus 로고
    • Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci
    • X Jiang A Hitchcock EJ Bryan 1996 Microsatellite analysis of endometriosis reveals loss of heterozygosity at candidate ovarian tumor suppressor gene loci Cancer Res 56 3534 3539
    • (1996) Cancer Res , vol.56 , pp. 3534-3539
    • Jiang, X.1    Hitchcock, A.2    Bryan, E.J.3
  • 88
    • 0030059759 scopus 로고    scopus 로고
    • Contiguous patches of normal human mammary epithelium derived from a single stem cell: Implications for breast carcinogenesis
    • YC Tsai Y Lu PW Nichols G Zlotnikov PA Jones HS Smith 1996 Contiguous patches of normal human mammary epithelium derived from a single stem cell: implications for breast carcinogenesis Cancer Res 56 402 404
    • (1996) Cancer Res , vol.56 , pp. 402-404
    • Tsai, Y.C.1    Lu, Y.2    Nichols, P.W.3    Zlotnikov, G.4    Jones, P.A.5    Smith, H.S.6
  • 89
    • 34247117277 scopus 로고    scopus 로고
    • Evidence for a stem cell hierarchy in the adult human breast
    • 10.1083/jcb.200611114
    • R Villadsen AJ Fridriksdottir L Ronnov-Jessen 2007 Evidence for a stem cell hierarchy in the adult human breast J Cell Biol 177 87 101 10.1083/jcb.200611114
    • (2007) J Cell Biol , vol.177 , pp. 87-101
    • Villadsen, R.1    Fridriksdottir, A.J.2    Ronnov-Jessen, L.3
  • 90
    • 4344713690 scopus 로고    scopus 로고
    • Assessment of clonal relationships in ipsilateral and bilateral multiple breast carcinomas by comparative genomic hybridisation and hierarchical clustering analysis
    • MR Teixeira FR Ribeiro L Torres 2004 Assessment of clonal relationships in ipsilateral and bilateral multiple breast carcinomas by comparative genomic hybridisation and hierarchical clustering analysis Br J Cancer 91 775 782
    • (2004) Br J Cancer , vol.91 , pp. 775-782
    • Teixeira, M.R.1    Ribeiro, F.R.2    Torres, L.3
  • 91
    • 0037015185 scopus 로고    scopus 로고
    • Breast cancer screening: A summary of the evidence for the U.S. Preventive Services Task Force
    • LL Humphrey M Helfand BK Chan SH Woolf 2002 Breast cancer screening: a summary of the evidence for the U.S. Preventive Services Task Force Ann Intern Med 137 347 360
    • (2002) Ann Intern Med , vol.137 , pp. 347-360
    • Humphrey, L.L.1    Helfand, M.2    Chan, B.K.3    Woolf, S.H.4
  • 92
    • 4143099310 scopus 로고    scopus 로고
    • Functional maps of metastases from breast cancers: Proof of the principle that multidimensional scaling can summarize disease progression
    • 10.1007/s00268-004-7207-9
    • LC Gray JS Vaidya M Baum 2004 Functional maps of metastases from breast cancers: proof of the principle that multidimensional scaling can summarize disease progression World J Surg 28 646 651 10.1007/s00268-004-7207-9
    • (2004) World J Surg , vol.28 , pp. 646-651
    • Gray, L.C.1    Vaidya, J.S.2    Baum, M.3
  • 93
    • 0030772811 scopus 로고    scopus 로고
    • Widely dispersed p53 mutation in respiratory epithelium. a novel mechanism for field carcinogenesis
    • 10.1172/JCI119748
    • WA Franklin AF Gazdar J Haney 1997 Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis J Clin Invest 100 2133 2137 10.1172/JCI119748
    • (1997) J Clin Invest , vol.100 , pp. 2133-2137
    • Franklin, W.A.1    Gazdar, A.F.2    Haney, J.3
  • 94
    • 0033520789 scopus 로고    scopus 로고
    • Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer
    • 10.1093/jnci/91.21.1863
    • IW Park I Wistuba A Maitra 1999 Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer J Natl Cancer Inst 91 1863 1868 10.1093/jnci/91.21.1863
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1863-1868
    • Park, I.W.1    Wistuba, I.2    Maitra, A.3
  • 95
    • 25444482608 scopus 로고    scopus 로고
    • Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines
    • 10.1158/0008-5472.CAN-05-0931
    • M Locke M Heywood S Fawell IC Mackenzie 2005 Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines Cancer Res 65 8944 8950 10.1158/0008-5472.CAN-05-0931
    • (2005) Cancer Res , vol.65 , pp. 8944-8950
    • Locke, M.1    Heywood, M.2    Fawell, S.3    MacKenzie, I.C.4
  • 96
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • 10.1038/nature05236
    • S Bao Q Wu RE McLendon 2006 Glioma stem cells promote radioresistance by preferential activation of the DNA damage response Nature 444 756 760 10.1038/nature05236
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3
  • 97
    • 33646376411 scopus 로고    scopus 로고
    • Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
    • 10.1038/nature04703
    • OH Yilmaz R Valdez BK Theisen 2006 Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells Nature 441 475 482 10.1038/nature04703
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3
  • 98
    • 34848866647 scopus 로고    scopus 로고
    • Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4
    • 10.1016/j.stem.2007.08.001
    • M Todaro MP Alea AB Di Stefano 2007 Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4 Cell Stem Cell 1 389 402 10.1016/j.stem.2007.08.001
    • (2007) Cell Stem Cell , vol.1 , pp. 389-402
    • Todaro, M.1    Alea, M.P.2    Di Stefano, A.B.3
  • 99
    • 33846029123 scopus 로고    scopus 로고
    • A perivascular niche for brain tumor stem cells
    • 10.1016/j.ccr.2006.11.020
    • C Calabrese H Poppleton M Kocak 2007 A perivascular niche for brain tumor stem cells Cancer Cell 11 69 82 10.1016/j.ccr.2006.11.020
    • (2007) Cancer Cell , vol.11 , pp. 69-82
    • Calabrese, C.1    Poppleton, H.2    Kocak, M.3
  • 100
    • 3543013149 scopus 로고    scopus 로고
    • Functional outcomes of transoral laser surgery of supraglottic carcinoma compared with a transcervical approach
    • 10.1002/hed.20063
    • R Cabanillas JP Rodrigo JL Llorente V Suarez P Ortega C Suarez 2004 Functional outcomes of transoral laser surgery of supraglottic carcinoma compared with a transcervical approach Head Neck 26 653 659 10.1002/hed.20063
    • (2004) Head Neck , vol.26 , pp. 653-659
    • Cabanillas, R.1    Rodrigo, J.P.2    Llorente, J.L.3    Suarez, V.4    Ortega, P.5    Suarez, C.6
  • 101
    • 0029919276 scopus 로고    scopus 로고
    • Management of carcinoma of the supraglottic larynx: Evolution, current concepts, and future trends
    • 10.1097/00005537-199605000-00008
    • EN Myers A Alvi 1996 Management of carcinoma of the supraglottic larynx: evolution, current concepts, and future trends Laryngoscope 106 559 567 10.1097/00005537-199605000-00008
    • (1996) Laryngoscope , vol.106 , pp. 559-567
    • Myers, E.N.1    Alvi, A.2
  • 103
    • 40449135132 scopus 로고    scopus 로고
    • Organ-preservation surgery following failed radiotherapy for laryngeal cancer. Evaluation, patient selection, functional outcome and survival
    • G Marioni R Marchese-Ragona M Lucioni A Staffieri 2008 Organ-preservation surgery following failed radiotherapy for laryngeal cancer. Evaluation, patient selection, functional outcome and survival Curr Opin Otolaryngol Head Neck Surg 16 141 146
    • (2008) Curr Opin Otolaryngol Head Neck Surg , vol.16 , pp. 141-146
    • Marioni, G.1    Marchese-Ragona, R.2    Lucioni, M.3    Staffieri, A.4


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