Organ-preservation surgery following failed radiotherapy for laryngeal cancer. Evaluation, patient selection, functional outcome and survival

Current Opinion in Otolaryngology and Head and Neck Surgery

Volumn 16, Issue 2, 2008, Pages 141-146

  Marioni, Gino ^a   Marchese Ragona, Rosario ^a   Lucioni, Marco ^b   Staffieri, Alberto ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b Vittorio Veneto Hospital   (Italy)

Author keywords

Irradiation failure; Laryngeal carcinoma; Partial laryngectomy; Recurrence; Salvage laryngectomy

Indexed keywords

CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; HUMAN; IRRADIATION; LARYNGECTOMY; LARYNX CANCER; LARYNX EDEMA; LARYNX STENOSIS; MORBIDITY; PNEUMONIA; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REVIEW; SWALLOWING; TRACHEOSTOMY; TREATMENT FAILURE;

HUMANS; LARYNGEAL NEOPLASMS; LARYNGECTOMY; LARYNX; NEOPLASM RECURRENCE, LOCAL; PATIENT SELECTION; RECOVERY OF FUNCTION; SALVAGE THERAPY; TREATMENT FAILURE;

EID: 40449135132     PISSN: 10689508     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOO.0b013e3282f495a2     Document Type: Review

References (32)

1. Yiotakis J, Stavroulaki P, Nikolopoulos T, et al. Partial laryngectomy after irradiation failure. Otolaryngol Head Neck Surg 2003; 128:200-209.
2. Brandenburg JH, Condon KG, Frank TW. Coronal sections of larynges from radiation-therapy failures: a clinical-pathologic study. Otolaryngol Head Neck Surg 1986; 95:213-218.
3. Zbären P, Nuyens M, Curschmann J, Stauffer E. Histologic characteristics and tumor spread of recurrent glottic carcinoma: analysis on whole-organ sections and comparison with tumor spread of primary carcinomas. Head Neck 2007; 29:26-32. The authors analysed histologic characteristics of 29 laryngeal recurrent carcinomas. They concluded that recurrent laryngeal tumours are often significantly understaged by endoscopy and imaging studies.
4. Marchese-Ragona R, Marioni G, Chiarello G, et al. Supracricoid laryngectomy with cricohyoidopexy for recurrence of early-stage glottic carcinoma after irradiation. Long-term oncological and functional results. Acta Otolaryngol (Stockh) 2005; 125:91-95.
5. Ganly I, Patel SG, Matsuo J, et al. Results of surgical salvage after failure of definitive radiation therapy for early-stage squamous cell carcinoma of the glottic larynx. Arch Otolaryngol Head Neck Surg 2006; 132:59-66.
6. Marioni G, Marchese-Ragona R, Cartei G, et al. Current opinion in diagnosis and treatment of laryngeal carcinoma. Cancer Treatment Rev 2006; 32:504-515.
7. De Bree R, van der Putten L, Hoekstra OS, et al., on behalf of the RELAPS Study Group. A randomized trial of PET scanning to improve diagnostic yield of direct laryngoscopy in patients with suspicion of recurrent laryngeal carcinoma after radiotherapy. Contemp Clin Trials 2007; 28:705-712. The Recurrence Laryngeal Carcinoma PET Study was designed to evaluate the value of FDG-PET in the selection for direct laryngoscopy in patients of patients with suspicion of recurrent carcinoma after radiotherapy.
8. Zbären P, Christe A, Caversaccio MD, et al. Pretherapeutic staging of recurrent laryngeal carcinoma: clinical findings and imaging studies compared with histopathology. Otolaryngol Head Neck Surg 2007; 137:487-491. A retrospective study was performed on 42 recurrent laryngeal carcinomas: histologic findings were compared with the findings of the different preoperative diagnostic modalities.
9. Zbären P, Caversaccio M, Thoeny HC, et al. Radionecrosis or tumor recurrence after radiation of laryngeal and hypopharyngeal carcinomas. Otolaryngol Head Neck Surg 2007; 135:838-843. Chondroradionecrosis is an uncommon treatment complication: tumour recurrence may be present beneath intact mucosa and missed by endoscopic evaluation.
10. Bradley PJ, Ferlito A, Suarez C, et al. Options for salvage after failed initial treatment of anterior vocal commissure squamous carcinoma. Eur Arch Otorhinolaryngol 2006; 263:889-894.
11. Thoeny HC, Delaere PR, Hermans R. Correlation of local outcome after partial laryngectomy with cartilage abnormalities on CT. AJNR Am J Neuroradiol 2005; 26:674-678.
12. Becker M. Neoplastic invasion of laryngeal cartilage: radiologic diagnosis and therapeutic implications. Eur J Radiol 2000; 33:216-229.
13. Esclamado R, Day T, Flint P, Strome M. Recurrent glottic cancer. Head Neck 2007; 29:609-614. This reports on an interesting and detailed roundtable with a consultant and three experts regarding the rational salvage approaches to a case of recurrent glottic carcinoma after radiotherapy failure. The section regarding correct carcinoma recurrence correct staging is remarkable.
14. Knappe M, Louw M, Gregor RT. Ultrasonography-guided fine needle aspiration for the assessment of cervical metastases. Arch Otolaryngol Head Neck Surg 2000; 126:1091-1096.
15. Session RB, Picken CA. Malignant cervical adenopathy. In: Cummings CW, Fredrickson JM, Harker LA, et al., editors. Otolaryngology head and neck surgery. St Louis: Mosby-Year Book; 1998. pp. 737-757.
16. Holsinger FC, Funk E, Roberts DB, Diaz DM. Conservation lartyngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer. Head Neck 2006; 28:779-784.
17. Piazza C, Peretti G, Cattaneo A, et al. Salvage surgery after radiotherapy for laryngeal cancer: from endoscopic resections to open-neck partial and total laryngectomies. Arch Otolaryngol Head Neck Surg 2007; 133:1037-1043. The authors discussed the results of 71 patients with laryngeal carcinoma previously treated with radiotherapy (69 patients) and chemoradiotherapy (two patients) who underwent salvage surgery. The authors concluded that the survival rates of their series were not different from those previously reported using a more aggressive surgical approach without organ preservation.
18. Motamed M, Laccourreye O, Bradley PJ. Salvage conservation laryngeal surgery after irradiation failure for early laryngeal cancer. Laryngoscope 2006; 116:451-455.
19. Rifai M, Heiba MH, Salah H. Anterior commissure carcinoma II: the role of salvage supracricoid laryngectomy. Am J Otolaryngol 2002; 23:1-3.
20. Steiner W, Vogt P, Ambrosch P, Kron M. Transoral carbon dioxide laser microsurgery for recurrent glottic carcinoma after radiotherapy. Head Neck 2004; 26:477-484.
21. Rizzotto G, Succo G, Lucioni M, Pazzaia T. Subtotal laryngectomy with tracheohyoidopexy: a possibile alternative to total laryngectomy. Laryngoscope 2006; 116:1907-1917.
22. Marioni G, Marchese-Ragona R, Pastore A, Staffieri A. The role of supracricoid partial laryngectomy for glottic carcinoma recurrence after radiotherapy failure. A critical review. Acta Otolaryngol (Stockh) 2006; 126:1245-1251.
23. Farrag T, Koch WM, Cummings CW, et al. Supracricoid laryngectomy outcomes: the John Hopkins experience. Laryngoscope 2007; 117:129-132. The authors reviewed 24 consecutive cases of SCL performed in a 5-year period. Ten of them had their SCL for post-radiotherapy recurrence/persistence of disease.
24. Hofmann-Saguez MR. Laryngectomie subtotale conservatrice. Ann Otolaryngol 1950; 67:811-816.
25. Pellini R, Pichi B, Ruscito P, et al. Supracricoid partial laryngectomies after radiation failure: a multiinstitutional series. Head Neck 2007; 30 Oct [Epub ahead of print]. A multiinstitutional series of 78 cases of SCL for carcinoma recurrence after radiotherapy: a significant number of these case were previously reported in single-institution experiences. After their analysis, the authors concluded that SCLs as salvage treatment modalities after radiotherapy failure should be considered as an effective tool in the modern surgical armamentarium.
26. Marioni G, Marchese-Ragona R, Ottaviano G, Staffieri A. Supracricoid laryngectomy. Is it time to define guidelines to evaluate functional results? A review. Am J Otolaryngol 2004; 25:98-104.
27. Laccourreye O, Weinstein G, Naudo P, et al. Supracricoid partial laryngectomy after failed laryngeal radiation therapy. Laryngoscope 1996; 106:495-498.
28. Pellini R, Manciocco V, Spriano G. Functional outcome of supracricoid laryngectomy with cricohyoidopexy. Radiation failure vs previously untreated cases. Arch Otolaryngol Head Neck Surg 2006; 132:1221-1225.
29. Leon X, Lopez M, Garcia J, et al. Supracricoid laryngectomy as salvage surgery after failure of radiation therapy. Eur Arch Otorhinolaryngol 2007; 264:809-814. The authors reported oncological and functional results of nine consecutive patients treated with SCL for glottic-supraglottic carcinoma recurrence after radiotherapy.
30. Sewnaik A, Meeuwis CA, Van Der Kwast TH, Kerrebijn JDF. Partial laryngectomy for recurrent glottic carcinoma after radiotherapy. Head Neck 2005; 27:101-107.
31. Farrag TY, Lin FR, Cummings CW, et al. Neck management in patients undergoing postradiotherapy salvage laryngeal surgery for recurrent/persistent laryngeal cancer. Laryngoscope 2006; 116:1864-1866.
32. Marioni G, Marino F, Bertolin A, et al. Survivin expression in laryngeal squamous cell carcinomas and neck lymph node metastases. Anticancer Res 2006; 26:3813-3818.