Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion

PLoS ONE

Volumn 3, Issue 12, 2008, Pages

  González Barroso, M Mar ^a,b   Giurgea, Irina ^a   Bouillaud, Fredéric ^a   Anedda, Andrea ^b   Bellanné Chantelot, Christine ^c   Hubert, Laurence ^a   de Keyzer, Yvez ^a   de Lonlay, Pascale ^a   Ricquier, Daniel ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DIAZOXIDE; MUTANT PROTEIN; UNCOUPLING PROTEIN 2; GLUCOSE; INSULIN; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; PROTON; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GLUCOSE METABOLISM; HETEROZYGOTE; HORMONAL REGULATION; HUMAN; INSULIN RELEASE; MITOCHONDRION; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PERSISTENT HYPERINSULINEMIC HYPOGLYCEMIA OF INFANCY; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; YEAST; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECT; FEMALE; GENETICS; INFANT; MALE; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; PEDIGREE; RAT; SACCHAROMYCES CEREVISIAE; SECRETION; SPHEROPLAST;

MUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CONSERVED SEQUENCE; DNA MUTATIONAL ANALYSIS; FEMALE; GLUCOSE; HETEROZYGOTE; HUMANS; INFANT; INSULIN; INSULIN-SECRETING CELLS; ION CHANNELS; MALE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION, MISSENSE; PEDIGREE; PERSISTENT HYPERINSULINEMIA HYPOGLYCEMIA OF INFANCY; PROTONS; RATS; SACCHAROMYCES CEREVISIAE; SPHEROPLASTS;

EID: 57549099212     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003850     Document Type: Article

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