메뉴 건너뛰기




Volumn 273, Issue 2, 2009, Pages 281-291

hCCR4/cNOT6 targets DNA-damage response proteins

Author keywords

CCR4 CNOT complex; Chk2; Cisplatin; H2AX

Indexed keywords

ALPHA TUBULIN; ATM PROTEIN; ATR PROTEIN; BLEOMYCIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CHEMOKINE RECEPTOR CCR4; CISPLATIN; DNA DAMAGE RESPONSE PROTEIN; DNA FRAGMENT; GENE PRODUCT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE H2AX; HYDROXYUREA; PROTEIN CNOT6; PROTEIN HCCR4; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 57349131611     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.08.026     Document Type: Article
Times cited : (11)

References (50)
  • 2
    • 38449088673 scopus 로고    scopus 로고
    • Signalling pathways involved in clinical responses to chemotherapy
    • Perona R., and Sanchez-Perez I. Signalling pathways involved in clinical responses to chemotherapy. Clin. Transl. Oncol. 9 (2007) 625-633
    • (2007) Clin. Transl. Oncol. , vol.9 , pp. 625-633
    • Perona, R.1    Sanchez-Perez, I.2
  • 4
    • 42149126036 scopus 로고    scopus 로고
    • ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis
    • Pabla N., Huang S., Mi Q.S., Daniel R., and Dong Z. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. J. Biol. Chem. (2007)
    • (2007) J. Biol. Chem.
    • Pabla, N.1    Huang, S.2    Mi, Q.S.3    Daniel, R.4    Dong, Z.5
  • 5
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: taking shape
    • Shiloh Y. The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31 (2006) 402-410
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 402-410
    • Shiloh, Y.1
  • 6
    • 0035848819 scopus 로고    scopus 로고
    • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
    • Falck J., Mailand N., Syljuasen R.G., Bartek J., and Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410 (2001) 842-847
    • (2001) Nature , vol.410 , pp. 842-847
    • Falck, J.1    Mailand, N.2    Syljuasen, R.G.3    Bartek, J.4    Lukas, J.5
  • 7
    • 0035393594 scopus 로고    scopus 로고
    • DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology
    • Lukas C., Bartkova J., Latella L., Falck J., Mailand N., Schroeder T., Sehested M., Lukas J., and Bartek J. DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology. Cancer Res. 61 (2001) 4990-4993
    • (2001) Cancer Res. , vol.61 , pp. 4990-4993
    • Lukas, C.1    Bartkova, J.2    Latella, L.3    Falck, J.4    Mailand, N.5    Schroeder, T.6    Sehested, M.7    Lukas, J.8    Bartek, J.9
  • 9
    • 0038054343 scopus 로고    scopus 로고
    • The Chk2 tumor suppressor is not required for p53 responses in human cancer cells
    • Jallepalli P.V., Lengauer C., Vogelstein B., and Bunz F. The Chk2 tumor suppressor is not required for p53 responses in human cancer cells. J. Biol. Chem. 278 (2003) 20475-20479
    • (2003) J. Biol. Chem. , vol.278 , pp. 20475-20479
    • Jallepalli, P.V.1    Lengauer, C.2    Vogelstein, B.3    Bunz, F.4
  • 10
    • 34547100275 scopus 로고    scopus 로고
    • The resurgence of platinum-based cancer chemotherapy
    • Kelland L. The resurgence of platinum-based cancer chemotherapy. Nat. Rev. Cancer 7 (2007) 573-584
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 573-584
    • Kelland, L.1
  • 12
    • 0026547681 scopus 로고
    • Isolation of dominant negative mutants and inhibitory antisense RNA sequences by expression selection of random DNA fragments
    • Holzmayer T.A., Pestov D.G., and Roninson I.B. Isolation of dominant negative mutants and inhibitory antisense RNA sequences by expression selection of random DNA fragments. Nucleic Acids Res. 20 (1992) 711-717
    • (1992) Nucleic Acids Res. , vol.20 , pp. 711-717
    • Holzmayer, T.A.1    Pestov, D.G.2    Roninson, I.B.3
  • 13
    • 0028216322 scopus 로고
    • Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization
    • Gudkov A.V., Kazarov A.R., Thimmapaya R., Axenovich S.A., Mazo I.A., and Roninson I.B. Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization. Proc. Natl. Acad. Sci. USA 91 (1994) 3744-3748
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3744-3748
    • Gudkov, A.V.1    Kazarov, A.R.2    Thimmapaya, R.3    Axenovich, S.A.4    Mazo, I.A.5    Roninson, I.B.6
  • 16
    • 57349197563 scopus 로고    scopus 로고
    • A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase deficient human cells
    • Machado-Pinilla R., Sanchez-Perez I., Murguia J.R., Sastre L., and Perona R. A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase deficient human cells. Blood (2007)
    • (2007) Blood
    • Machado-Pinilla, R.1    Sanchez-Perez, I.2    Murguia, J.R.3    Sastre, L.4    Perona, R.5
  • 17
    • 0035947778 scopus 로고    scopus 로고
    • Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
    • Novoa I., Zeng H., Harding H.P., and Ron D. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J. Cell Biol. 153 (2001) 1011-1022
    • (2001) J. Cell Biol. , vol.153 , pp. 1011-1022
    • Novoa, I.1    Zeng, H.2    Harding, H.P.3    Ron, D.4
  • 18
    • 0021702006 scopus 로고
    • Identification of new genes involved in the regulation of yeast alcohol dehydrogenase II
    • Denis C.L. Identification of new genes involved in the regulation of yeast alcohol dehydrogenase II. Genetics 108 (1984) 833-844
    • (1984) Genetics , vol.108 , pp. 833-844
    • Denis, C.L.1
  • 19
    • 0032481349 scopus 로고    scopus 로고
    • The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively
    • Liu H.Y., Badarinarayana V., Audino D.C., Rappsilber J., Mann M., and Denis C.L. The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively. EMBO J. 17 (1998) 1096-1106
    • (1998) EMBO J. , vol.17 , pp. 1096-1106
    • Liu, H.Y.1    Badarinarayana, V.2    Audino, D.C.3    Rappsilber, J.4    Mann, M.5    Denis, C.L.6
  • 20
    • 0035831551 scopus 로고    scopus 로고
    • Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme
    • Liu H.Y., Chiang Y.C., Pan J., Chen J., Salvadore C., Audino D.C., Badarinarayana V., Palaniswamy V., Anderson B., and Denis C.L. Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme. J. Biol. Chem. 276 (2001) 7541-7548
    • (2001) J. Biol. Chem. , vol.276 , pp. 7541-7548
    • Liu, H.Y.1    Chiang, Y.C.2    Pan, J.3    Chen, J.4    Salvadore, C.5    Audino, D.C.6    Badarinarayana, V.7    Palaniswamy, V.8    Anderson, B.9    Denis, C.L.10
  • 21
    • 0033911879 scopus 로고    scopus 로고
    • Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast
    • Badarinarayana V., Chiang Y.C., and Denis C.L. Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155 (2000) 1045-1054
    • (2000) Genetics , vol.155 , pp. 1045-1054
    • Badarinarayana, V.1    Chiang, Y.C.2    Denis, C.L.3
  • 22
    • 0035830508 scopus 로고    scopus 로고
    • The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae
    • Tucker M., Valencia-Sanchez M.A., Staples R.R., Chen J., Denis C.L., and Parker R. The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell 104 (2001) 377-386
    • (2001) Cell , vol.104 , pp. 377-386
    • Tucker, M.1    Valencia-Sanchez, M.A.2    Staples, R.R.3    Chen, J.4    Denis, C.L.5    Parker, R.6
  • 23
    • 0037086657 scopus 로고    scopus 로고
    • Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae
    • Tucker M., Staples R.R., Valencia-Sanchez M.A., Muhlrad D., and Parker R. Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae. EMBO J. 21 (2002) 1427-1436
    • (2002) EMBO J. , vol.21 , pp. 1427-1436
    • Tucker, M.1    Staples, R.R.2    Valencia-Sanchez, M.A.3    Muhlrad, D.4    Parker, R.5
  • 24
    • 0037086701 scopus 로고    scopus 로고
    • CCR4, a 3′-5′ poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase
    • Chen J., Chiang Y.C., and Denis C.L. CCR4, a 3′-5′ poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase. EMBO J. 21 (2002) 1414-1426
    • (2002) EMBO J. , vol.21 , pp. 1414-1426
    • Chen, J.1    Chiang, Y.C.2    Denis, C.L.3
  • 25
    • 13744256106 scopus 로고    scopus 로고
    • Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae
    • Westmoreland T.J., Marks J.R., Olson Jr. J.A., Thompson E.M., Resnick M.A., and Bennett C.B. Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae. Eukaryoti Cell 3 (2004) 430-436
    • (2004) Eukaryoti Cell , vol.3 , pp. 430-436
    • Westmoreland, T.J.1    Marks, J.R.2    Olson Jr., J.A.3    Thompson, E.M.4    Resnick, M.A.5    Bennett, C.B.6
  • 26
    • 13744257324 scopus 로고    scopus 로고
    • Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiae
    • Traven A., Hammet A., Tenis N., Denis C.L., and Heierhorst J. Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiae. Genetics 169 (2005) 65-75
    • (2005) Genetics , vol.169 , pp. 65-75
    • Traven, A.1    Hammet, A.2    Tenis, N.3    Denis, C.L.4    Heierhorst, J.5
  • 27
    • 9144252209 scopus 로고    scopus 로고
    • 2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding
    • 2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding. BMC Genomics 2 (2001) 9
    • (2001) BMC Genomics , vol.2 , pp. 9
    • Dupressoir, A.1    Morel, A.P.2    Barbot, W.3    Loireau, M.P.4    Corbo, L.5    Heidmann, T.6
  • 28
    • 1642483755 scopus 로고    scopus 로고
    • Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex
    • Zwartjes C.G., Jayne S., van den Berg D.L., and Timmers H.T. Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex. J. Biol. Chem. 279 (2004) 10848-10854
    • (2004) J. Biol. Chem. , vol.279 , pp. 10848-10854
    • Zwartjes, C.G.1    Jayne, S.2    van den Berg, D.L.3    Timmers, H.T.4
  • 29
    • 34347338699 scopus 로고    scopus 로고
    • Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth
    • Morita M., Suzuki T., Nakamura T., Yokoyama K., Miyasaka T., and Yamamoto T. Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Mol. Cell. Biol. 27 (2007) 4980-4990
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 4980-4990
    • Morita, M.1    Suzuki, T.2    Nakamura, T.3    Yokoyama, K.4    Miyasaka, T.5    Yamamoto, T.6
  • 30
    • 4143055666 scopus 로고    scopus 로고
    • The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?
    • Collart M.A., and Timmers H.T. The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?. Prog. Nucleic Acid Res. Mol. Biol. 77 (2004) 289-322
    • (2004) Prog. Nucleic Acid Res. Mol. Biol. , vol.77 , pp. 289-322
    • Collart, M.A.1    Timmers, H.T.2
  • 31
    • 43749087387 scopus 로고    scopus 로고
    • Components of the CCR4-not complex function as nuclear hormone receptor coactivators via association with the NRC interacting factor, NIF-1
    • Garapaty S.R., Mahajan M.A., and Samuels H.H. Components of the CCR4-not complex function as nuclear hormone receptor coactivators via association with the NRC interacting factor, NIF-1. J. Biol. Chem. (2008)
    • (2008) J. Biol. Chem.
    • Garapaty, S.R.1    Mahajan, M.A.2    Samuels, H.H.3
  • 32
    • 0036679169 scopus 로고    scopus 로고
    • Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability
    • Sanchez-Perez I., Benitah S.A., Martinez-Gomariz M., Lacal J.C., and Perona R. Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability. Mol. Biol. Cell 13 (2002) 2933-2945
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2933-2945
    • Sanchez-Perez, I.1    Benitah, S.A.2    Martinez-Gomariz, M.3    Lacal, J.C.4    Perona, R.5
  • 33
    • 0032576868 scopus 로고    scopus 로고
    • Cisplatin induces a persistent activation of JNK that is related to cell death
    • Sanchez-Perez I., Murguia J.R., and Perona R. Cisplatin induces a persistent activation of JNK that is related to cell death. Oncogene 16 (1998) 533-540
    • (1998) Oncogene , vol.16 , pp. 533-540
    • Sanchez-Perez, I.1    Murguia, J.R.2    Perona, R.3
  • 34
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3 (2003) 155-168
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 36
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist C.J., and Kastan M.B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421 (2003) 499-506
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 37
    • 0034326802 scopus 로고    scopus 로고
    • Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation
    • Ahn J.Y., Schwarz J.K., Piwnica-Worms H., and Canman C.E. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res. 60 (2000) 5934-5936
    • (2000) Cancer Res. , vol.60 , pp. 5934-5936
    • Ahn, J.Y.1    Schwarz, J.K.2    Piwnica-Worms, H.3    Canman, C.E.4
  • 42
    • 34548548790 scopus 로고    scopus 로고
    • Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae
    • Mulder K.W., Inagaki A., Cameroni E., Mousson F., Winkler G.S., De Virgilio C., Collart M.A., and Timmers H.T. Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae. Genetics 176 (2007) 181-192
    • (2007) Genetics , vol.176 , pp. 181-192
    • Mulder, K.W.1    Inagaki, A.2    Cameroni, E.3    Mousson, F.4    Winkler, G.S.5    De Virgilio, C.6    Collart, M.A.7    Timmers, H.T.8
  • 43
    • 0037224585 scopus 로고    scopus 로고
    • Identification of new drug sensitivity genes using genetic suppressor elements: protein arginine N-methyltransferase mediates cell sensitivity to DNA-damaging agents
    • Gros L., Delaporte C., Frey S., Decesse J., de Saint-Vincent B.R., Cavarec L., Dubart A., Gudkov A.V., and Jacquemin-Sablon A. Identification of new drug sensitivity genes using genetic suppressor elements: protein arginine N-methyltransferase mediates cell sensitivity to DNA-damaging agents. Cancer Res. 63 (2003) 164-171
    • (2003) Cancer Res. , vol.63 , pp. 164-171
    • Gros, L.1    Delaporte, C.2    Frey, S.3    Decesse, J.4    de Saint-Vincent, B.R.5    Cavarec, L.6    Dubart, A.7    Gudkov, A.V.8    Jacquemin-Sablon, A.9
  • 45
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 46
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: putting checkpoints in perspective
    • Zhou B.B., and Elledge S.J. The DNA damage response: putting checkpoints in perspective. Nature 408 (2000) 433-439
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2
  • 49
    • 0035823105 scopus 로고    scopus 로고
    • Antisense inhibition of Chk2/hCds1 expression attenuates DNA damage-induced S and G2 checkpoints and enhances apoptotic activity in HEK-293 cells
    • Yu Q., Rose J.H., Zhang H., and Pommier Y. Antisense inhibition of Chk2/hCds1 expression attenuates DNA damage-induced S and G2 checkpoints and enhances apoptotic activity in HEK-293 cells. FEBS Lett. 505 (2001) 7-12
    • (2001) FEBS Lett. , vol.505 , pp. 7-12
    • Yu, Q.1    Rose, J.H.2    Zhang, H.3    Pommier, Y.4
  • 50
    • 0038752083 scopus 로고    scopus 로고
    • Chk2 activates E2F-1 in response to DNA damage
    • Stevens C., Smith L., and La Thangue N.B. Chk2 activates E2F-1 in response to DNA damage. Nat. Cell Biol. 5 (2003) 401-409
    • (2003) Nat. Cell Biol. , vol.5 , pp. 401-409
    • Stevens, C.1    Smith, L.2    La Thangue, N.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.