The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

Cell

Volumn 104, Issue 3, 2001, Pages 377-386

  Tucker, Morgan ^a   Valencia Sanchez, Marco A ^a   Staples, Robin R ^a   Chen, Junji ^b   Denis, Clyde L ^b   Parker, Roy ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF NEW HAMPSHIRE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; EXONUCLEASE; FUNGAL ENZYME; MESSENGER RNA DEADENYLASE; PROTEIN CAF1; PROTEIN CCR4; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; GENE CONTROL; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RNA DEGRADATION; RNA SYNTHESIS; SACCHAROMYCES CEREVISIAE;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0035830508     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)00225-2     Document Type: Article

References (52)

1. Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits
2. The 3′ to 5′ degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3′ to 5′ exonucleases of the exosome complex
3. Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast
4. The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated form the NOT2, NOT4 and NOT5
5. Meiotic maturation in Xenopus requires polyadenylation of multiple mRNAs
6. Degradation of mRNA in eukaryotes
7. Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes
8. The yeast Pan2 protein is required for poly(A)-binding protein-stimulated poly(A)-nuclease activity
9. Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation
10. PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae
11. mRNA turnover in yeast promoted by the MATα1 instability element
12. A small segment of the MAT alpha 1 transcript promotes mRNA decay in Saccharomyces cerevisiae: A stimulatory role for rare codons
13. A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling
14. Messenger RNA deadenylation precedes decapping in mammalian cells
15. A turnover pathway for both stable and unstable mRNAs in yeast: Evidence for a requirement for deadenylation
16. Cap-dependent deadenylation of mRNA
17. The CCR4 gene from Saccharomyces cerevisiae is required for both nonfermentative and spt-mediated gene expression
18. +-dependent endonucleases
19. Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex
20. Interaction between a poly(A)-specific ribonuclease and the 5′ cap influences mRNA deadenylation rates in vitro
21. Control of translation initiation in animals
22. A mechanism for translationally coupled mRNA turnover: Interaction between the Poly(A) tail and a c-fos RNA coding determinant via a protein complex
23. Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae
24. Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiae
25. Yeast cells lacking 5′→3′ exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5′ cap structure
26. Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases
27. Poly(A) tail shortening by a mammalian poly(A)-specific 3′-exoribonuclease
28. The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes
29. Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme
30. The TATA-binding protein-associated factor yTafII19p functionally interacts with components of the global transcriptional regulator Ccr4-Not complex and physically interacts with the Not5 subunit
31. DBF2, a cell cycle-regulated protein kinase, is physically and functionally associated with the CCR4 transcriptional regulatory complex
32. The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively
33. Characterization of CAF4 and CAF16 reveal a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme
34. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
35. 3′-UTR-dependent deadenylation by the yeast poly(A) nuclease
36. A 54-kDa fragment of the Poly(A)-specific ribonuclease is an oligomeric, processive, and cap-interacting Poly(A)-specific 3′ exonuclease
37. The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains
38. Mutations affecting stability and deadenylation of the yeast MFA2 transcript
39. Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5′→3′ digestion of the transcript
40. Turnover mechanisms of the stable yeast PGK1 mRNA
41. Characterization of NOT5 that encodes a new component of the Not protein complex
42. The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast
43. Mecanismes d'action de BTG2, gene cible de p53: Donnees acquises et hypotheses
44. A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability
45. Starting at the beginning, middle, and end: Translation initiation in eukaryotes
46. Molecular analysis of POP2 gene, a gene required for glucose-derepression of gene expression in Saccharomyces cerevisiae
47. Vectors for constitutive and inducible gene expression in yeast
48. Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay
49. Analysis of mutations in the yeast mRNA decapping enzyme
50. The exosome: A proteasome for RNA?
51. Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AU-rich sequences
52. Nanos and pumilio establish embryonic polarity in Drosophila by promoting posterior deadenylation of hunchback mRNA