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Volumn 62, Issue 6 SUPPL., 2008, Pages

Genetic and cellular therapies for cerebral infarction

Author keywords

Cellular therapy; Cerebral infarct; Gene therapy; Neuroregeneration; Stem cells; Stroke

Indexed keywords

CYCLOSPORIN; CYTOKINE; REACTIVE OXYGEN METABOLITE; TACROLIMUS;

EID: 57049113195     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000129681.85731.00     Document Type: Review
Times cited : (5)

References (117)
  • 1
    • 0346970923 scopus 로고    scopus 로고
    • De novo neurogenesis and acute stroke: Are exogenous stem cells really necessary?
    • Abrahams JM, Gokhan S, Flamm ES, Mehler MF: De novo neurogenesis and acute stroke: Are exogenous stem cells really necessary? Neurosurgery 54:150-155, 2004.
    • (2004) Neurosurgery , vol.54 , pp. 150-155
    • Abrahams, J.M.1    Gokhan, S.2    Flamm, E.S.3    Mehler, M.F.4
  • 2
    • 0028213914 scopus 로고
    • Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat
    • Aihara N, Mizukawa K, Koide K, Mabe H, Nishimo H: Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat. Brain Res Bull 33:483-488, 1994.
    • (1994) Brain Res Bull , vol.33 , pp. 483-488
    • Aihara, N.1    Mizukawa, K.2    Koide, K.3    Mabe, H.4    Nishimo, H.5
  • 3
    • 0029962777 scopus 로고    scopus 로고
    • Over-expression of heat shock protein 70 protects neuronal cells against both thermal and ischaemic stress but with different efficiencies
    • Amin V, Gumming DV, Latchman DS: Over-expression of heat shock protein 70 protects neuronal cells against both thermal and ischaemic stress but with different efficiencies. Neurosci Lett 206:45-48, 1996.
    • (1996) Neurosci Lett , vol.206 , pp. 45-48
    • Amin, V.1    Gumming, D.V.2    Latchman, D.S.3
  • 4
    • 0027248015 scopus 로고
    • Neural grafting to ischemic CA1 lesions in the rat hippocampus: An autoradiographic study
    • Aoki H, Onodera H, Yae T, Jian Z, Kogure K: Neural grafting to ischemic CA1 lesions in the rat hippocampus: An autoradiographic study. Neuroscience 56:345-354, 1993.
    • (1993) Neuroscience , vol.56 , pp. 345-354
    • Aoki, H.1    Onodera, H.2    Yae, T.3    Jian, Z.4    Kogure, K.5
  • 5
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson A, Collin T, Kirik D, Kokaia Z, Lindvall O: Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 8:963-970, 2002.
    • (2002) Nat Med , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 6
    • 0019822988 scopus 로고
    • Thresholds in cerebral ischemia: The ischemic penumbra
    • Astrup J, Siesjö BK, Symon L: Thresholds in cerebral ischemia: The ischemic penumbra. Stroke 12:723-725, 1981.
    • (1981) Stroke , vol.12 , pp. 723-725
    • Astrup, J.1    Siesjö, B.K.2    Symon, L.3
  • 7
    • 0034977896 scopus 로고    scopus 로고
    • An efficient method for the culturing and generation of neurons and astrocytes from second trimester human central nervous system tissue
    • Barami K, Grever WE, Diaz FG, Lyman WD: An efficient method for the culturing and generation of neurons and astrocytes from second trimester human central nervous system tissue. Neurol Res 23:321-326, 2001.
    • (2001) Neurol Res , vol.23 , pp. 321-326
    • Barami, K.1    Grever, W.E.2    Diaz, F.G.3    Lyman, W.D.4
  • 8
    • 0037101634 scopus 로고    scopus 로고
    • The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury
    • Basu A, Krady JK, O'Malley M, Styren SD, DeKosky ST, Levison SW: The type 1 interleukin-1 receptor is essential for the efficient activation of microglia and the induction of multiple proinflammatory mediators in response to brain injury. J Neurosci 22:6071-6082, 2002.
    • (2002) J Neurosci , vol.22 , pp. 6071-6082
    • Basu, A.1    Krady, J.K.2    O'Malley, M.3    Styren, S.D.4    DeKosky, S.T.5    Levison, S.W.6
  • 9
    • 0033916716 scopus 로고    scopus 로고
    • Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice
    • Benninger Y, Marino S, Hardegger R, Weissmann C, Aguzzi A, Brandner S: Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice. Brain Pathol 10:330-341, 2000.
    • (2000) Brain Pathol , vol.10 , pp. 330-341
    • Benninger, Y.1    Marino, S.2    Hardegger, R.3    Weissmann, C.4    Aguzzi, A.5    Brandner, S.6
  • 10
    • 0033435198 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
    • Bergeron M, Yu AY, Solway KE, Semenza GL, Sharp FR: Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur J Neurosci 11:4159-4170, 1999.
    • (1999) Eur J Neurosci , vol.11 , pp. 4159-4170
    • Bergeron, M.1    Yu, A.Y.2    Solway, K.E.3    Semenza, G.L.4    Sharp, F.R.5
  • 11
    • 0032006347 scopus 로고    scopus 로고
    • Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats
    • Borlongan CV, Tajima Y, Trojanowski JQ, Lee VM, Sanberg PR: Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats. Exp Neurol 149:310-321, 1998.
    • (1998) Exp Neurol , vol.149 , pp. 310-321
    • Borlongan, C.V.1    Tajima, Y.2    Trojanowski, J.Q.3    Lee, V.M.4    Sanberg, P.R.5
  • 12
    • 0034531907 scopus 로고    scopus 로고
    • From marrow to brain: Expression of neuronal phenotypes in adult mice
    • Brazelton TR, Rossi FM, Keshet GI, Blau HM: From marrow to brain: Expression of neuronal phenotypes in adult mice. Science 290:1775-1779, 2000.
    • (2000) Science , vol.290 , pp. 1775-1779
    • Brazelton, T.R.1    Rossi, F.M.2    Keshet, G.I.3    Blau, H.M.4
  • 13
    • 0034255153 scopus 로고    scopus 로고
    • Xenotransplantation for CNS repair: Immunological barriers and strategies to overcome them
    • Brevig T, Holgersson J, Widner H: Xenotransplantation for CNS repair: Immunological barriers and strategies to overcome them. Trends Neurosci 23:337-344, 2000.
    • (2000) Trends Neurosci , vol.23 , pp. 337-344
    • Brevig, T.1    Holgersson, J.2    Widner, H.3
  • 14
    • 0036012750 scopus 로고    scopus 로고
    • Cloning and characterization of rat caspase-9: Implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia
    • Cao G, Luo Y, Nagayama T, Pei W, Stetler RA, Graham SH, Chen J: Cloning and characterization of rat caspase-9: Implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia. J Cereb Blood Flow Metab 22:534-546, 2002.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 534-546
    • Cao, G.1    Luo, Y.2    Nagayama, T.3    Pei, W.4    Stetler, R.A.5    Graham, S.H.6    Chen, J.7
  • 16
    • 0033974706 scopus 로고    scopus 로고
    • Intracerebral transplantation of bone marrow with BDNF after MCAo in rat
    • Chen J, Li Y, Chopp M: Intracerebral transplantation of bone marrow with BDNF after MCAo in rat. Neuropharmacology 39:711-716, 2000.
    • (2000) Neuropharmacology , vol.39 , pp. 711-716
    • Chen, J.1    Li, Y.2    Chopp, M.3
  • 17
    • 0035075998 scopus 로고    scopus 로고
    • Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats
    • Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, Chopp M: Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 32:1005-1011, 2001.
    • (2001) Stroke , vol.32 , pp. 1005-1011
    • Chen, J.1    Li, Y.2    Wang, L.3    Zhang, Z.4    Lu, D.5    Lu, M.6    Chopp, M.7
  • 18
    • 0035167706 scopus 로고    scopus 로고
    • Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats
    • Chen J, Sanberg PR, Li Y, Wang L, Lu M, Willing AE, Sanchez-Ramos J, Chopp M: Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 32:2682-2688, 2001.
    • (2001) Stroke , vol.32 , pp. 2682-2688
    • Chen, J.1    Sanberg, P.R.2    Li, Y.3    Wang, L.4    Lu, M.5    Willing, A.E.6    Sanchez-Ramos, J.7    Chopp, M.8
  • 19
    • 0034746380 scopus 로고    scopus 로고
    • NF-κB activation by N-CAM and cytokines in astrocytes is regulated by multiple protein kinases and redox modulation
    • Choi J, Krushel LA, Crossin KL: NF-κB activation by N-CAM and cytokines in astrocytes is regulated by multiple protein kinases and redox modulation. Glia 33:45-56, 2001.
    • (2001) Glia , vol.33 , pp. 45-56
    • Choi, J.1    Krushel, L.A.2    Crossin, K.L.3
  • 21
    • 0342872047 scopus 로고    scopus 로고
    • Exacerbation of cerebral injury in mice that express the P-selectin gene: Identification of P-selectin blockade as a new target for the treatment of stroke
    • Connolly ES Jr, Winfree CJ, Prestigiacomo CJ, Kim SC, Choudhri TF, Hoh BL, Naka Y, Solomon RA, Pinsky DJ: Exacerbation of cerebral injury in mice that express the P-selectin gene: Identification of P-selectin blockade as a new target for the treatment of stroke. Circ Res 81:304-310, 1997.
    • (1997) Circ Res , vol.81 , pp. 304-310
    • Connolly Jr, E.S.1    Winfree, C.J.2    Prestigiacomo, C.J.3    Kim, S.C.4    Choudhri, T.F.5    Hoh, B.L.6    Naka, Y.7    Solomon, R.A.8    Pinsky, D.J.9
  • 22
    • 0029855989 scopus 로고    scopus 로고
    • Network of tangential pathways for neuronal migration in adult mammalian brain
    • Doetsch F, Alvarez-Buylla A: Network of tangential pathways for neuronal migration in adult mammalian brain. Proc Natl Acad Sci U S A 93:14895-14900, 1996.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14895-14900
    • Doetsch, F.1    Alvarez-Buylla, A.2
  • 23
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A: Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97:703-716, 1999.
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 24
    • 0030979469 scopus 로고    scopus 로고
    • Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain
    • Doetsch F, Garcia-Verdugo JM, Alvarez-Buylla A: Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci 17:5046-5061, 1997.
    • (1997) J Neurosci , vol.17 , pp. 5046-5061
    • Doetsch, F.1    Garcia-Verdugo, J.M.2    Alvarez-Buylla, A.3
  • 25
    • 0030793781 scopus 로고    scopus 로고
    • Nestin expression in reactive astrocytes following focal cerebral ischemia in rats
    • Duggal N, Schmidt-Kastner R, Hakim AM: Nestin expression in reactive astrocytes following focal cerebral ischemia in rats. Brain Res 768:1-9, 1997.
    • (1997) Brain Res , vol.768 , pp. 1-9
    • Duggal, N.1    Schmidt-Kastner, R.2    Hakim, A.M.3
  • 26
    • 0037174639 scopus 로고    scopus 로고
    • Neural and immunological synaptic relations
    • Dustin ML, Colman DR: Neural and immunological synaptic relations. Science 298:785-789, 2002.
    • (2002) Science , vol.298 , pp. 785-789
    • Dustin, M.L.1    Colman, D.R.2
  • 27
    • 57049160193 scopus 로고    scopus 로고
    • EdgarDatabase: Diacrin. Dec. 31, 2002. 10-K report. Retrieved from Edgar Database. Available at http://www.sec.gov. Accessed April 21, 2004.
    • EdgarDatabase: Diacrin. Dec. 31, 2002. 10-K report. Retrieved from Edgar Database. Available at http://www.sec.gov. Accessed April 21, 2004.
  • 29
    • 0024232238 scopus 로고
    • Neural transplantation of horseradish peroxidase-labeled hippocampal cell suspensions in an experimental model of cerebral ischemia
    • Farber SD, Onifer SM, Kaseda Y, Murphy SH, Wells DG, Vietje BP, Wells J, Low WC: Neural transplantation of horseradish peroxidase-labeled hippocampal cell suspensions in an experimental model of cerebral ischemia. Prog Brain Res 78:103-107, 1988.
    • (1988) Prog Brain Res , vol.78 , pp. 103-107
    • Farber, S.D.1    Onifer, S.M.2    Kaseda, Y.3    Murphy, S.H.4    Wells, D.G.5    Vietje, B.P.6    Wells, J.7    Low, W.C.8
  • 31
    • 0033565709 scopus 로고    scopus 로고
    • Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain
    • Fricker RA, Carpenter MK, Winkler C, Greco C, Gates MA, Bjorklund A: Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain. J Neurosci 19:5990-6005, 1999.
    • (1999) J Neurosci , vol.19 , pp. 5990-6005
    • Fricker, R.A.1    Carpenter, M.K.2    Winkler, C.3    Greco, C.4    Gates, M.A.5    Bjorklund, A.6
  • 32
    • 0032858203 scopus 로고    scopus 로고
    • Differentiation and angiogenesis of central nervous system stem cells implanted with mesenchyme into ischemic rat brain
    • Fukunaga A, Uchida K, Hara K, Kuroshima Y, Kawase T: Differentiation and angiogenesis of central nervous system stem cells implanted with mesenchyme into ischemic rat brain. Cell Transplant 8:435-441, 1999.
    • (1999) Cell Transplant , vol.8 , pp. 435-441
    • Fukunaga, A.1    Uchida, K.2    Hara, K.3    Kuroshima, Y.4    Kawase, T.5
  • 33
    • 0028790262 scopus 로고
    • Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion
    • Garcia JH, Liu KF, Relton JK: Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion. Am J Pathol 147:1477-1486, 1995.
    • (1995) Am J Pathol , vol.147 , pp. 1477-1486
    • Garcia, J.H.1    Liu, K.F.2    Relton, J.K.3
  • 34
    • 0034600480 scopus 로고    scopus 로고
    • Neuroprotection in acute ischaemic stroke: A tale of for whom the bell tolls?
    • Gorelick PB: Neuroprotection in acute ischaemic stroke: A tale of for whom the bell tolls? Lancet 355:1925-1926, 2000.
    • (2000) Lancet , vol.355 , pp. 1925-1926
    • Gorelick, P.B.1
  • 35
    • 0034961705 scopus 로고    scopus 로고
    • Neuroimmunophilins: Novel neuroprotective and neuroregenerative targets
    • Guo X, Dillman JF III, Dawson VL, Dawson TM: Neuroimmunophilins: Novel neuroprotective and neuroregenerative targets. Ann Neurol 50:6-16, 2001.
    • (2001) Ann Neurol , vol.50 , pp. 6-16
    • Guo, X.1    Dillman III, J.F.2    Dawson, V.L.3    Dawson, T.M.4
  • 36
    • 0035838277 scopus 로고    scopus 로고
    • Neuroprotective effects of an adenoviral vector expressing the glucose transporter: A detailed description of the mediating cellular events
    • Gupta A, Ho DY, Brooke S, Franklin L, Roy M, McLaughlin J, Fink SL, Sapolsky RM: Neuroprotective effects of an adenoviral vector expressing the glucose transporter: A detailed description of the mediating cellular events. Brain Res 908:49-57, 2001.
    • (2001) Brain Res , vol.908 , pp. 49-57
    • Gupta, A.1    Ho, D.Y.2    Brooke, S.3    Franklin, L.4    Roy, M.5    McLaughlin, J.6    Fink, S.L.7    Sapolsky, R.M.8
  • 37
    • 0036908651 scopus 로고    scopus 로고
    • The many faces of tumor necrosis factor in stroke
    • Hallenbeck JM: The many faces of tumor necrosis factor in stroke. Nat Med 8:1363-1368, 2002.
    • (2002) Nat Med , vol.8 , pp. 1363-1368
    • Hallenbeck, J.M.1
  • 39
    • 0029082551 scopus 로고
    • Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults
    • Ho DY, Saydam TC, Fink SL, Lawrence MS, Sapolsky RM: Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults. J Neurochem 65:842-850, 1995.
    • (1995) J Neurochem , vol.65 , pp. 842-850
    • Ho, D.Y.1    Saydam, T.C.2    Fink, S.L.3    Lawrence, M.S.4    Sapolsky, R.M.5
  • 40
    • 0029877193 scopus 로고    scopus 로고
    • Contrasting effects of fetal CA1 and CA3 hippocampal grafts on deficits in spatial learning and working memory induced by global cerebral ischaemia in rats
    • Hodges H, Sowinski P, Fleming P, Kershaw TR, Sinden JD, Meldrum BS, Gray JA: Contrasting effects of fetal CA1 and CA3 hippocampal grafts on deficits in spatial learning and working memory induced by global cerebral ischaemia in rats. Neuroscience 72:959-988, 1996.
    • (1996) Neuroscience , vol.72 , pp. 959-988
    • Hodges, H.1    Sowinski, P.2    Fleming, P.3    Kershaw, T.R.4    Sinden, J.D.5    Meldrum, B.S.6    Gray, J.A.7
  • 41
    • 0030910650 scopus 로고    scopus 로고
    • bFGF ameliorates focal ischemic injury by blood flow-independent mechanisms in eNOS mutant mice
    • Huang Z, Chen K, Huang PL, Finklestein SP, Moskowitz MA: bFGF ameliorates focal ischemic injury by blood flow-independent mechanisms in eNOS mutant mice. Am J Physiol 272[Suppl 3]:H1401-H1405, 1997.
    • (1997) Am J Physiol , vol.272 , Issue.SUPPL. 3
    • Huang, Z.1    Chen, K.2    Huang, P.L.3    Finklestein, S.P.4    Moskowitz, M.A.5
  • 42
    • 0034846836 scopus 로고    scopus 로고
    • Cortical neurogenesis in adult rats after transient middle cerebral artery occlusion
    • Jiang W, Gu W, Brannstrom T, Rosqvist R, Wester P: Cortical neurogenesis in adult rats after transient middle cerebral artery occlusion. Stroke 32:1201-1207, 2001.
    • (2001) Stroke , vol.32 , pp. 1201-1207
    • Jiang, W.1    Gu, W.2    Brannstrom, T.3    Rosqvist, R.4    Wester, P.5
  • 43
    • 0033534379 scopus 로고    scopus 로고
    • Identification of a neural stem cell in the adult mammalian central nervous system
    • Johansson CB, Momma S, Clarke DL, Risling M, Lendahl U, Frisen J: Identification of a neural stem cell in the adult mammalian central nervous system. Cell 96:25-34, 1999.
    • (1999) Cell , vol.96 , pp. 25-34
    • Johansson, C.B.1    Momma, S.2    Clarke, D.L.3    Risling, M.4    Lendahl, U.5    Frisen, J.6
  • 44
    • 0035843974 scopus 로고    scopus 로고
    • Trophic factor secreting kidney cell lines: In vitro characterization and functional effects following transplantation in ischemic rats
    • Johnston RE, Dillon-Carter O, Freed WJ, Borlongan CV: Trophic factor secreting kidney cell lines: In vitro characterization and functional effects following transplantation in ischemic rats. Brain Res 900:268-276, 2001.
    • (2001) Brain Res , vol.900 , pp. 268-276
    • Johnston, R.E.1    Dillon-Carter, O.2    Freed, W.J.3    Borlongan, C.V.4
  • 45
    • 0033035315 scopus 로고    scopus 로고
    • Biochemical and molecular characteristics of the brain with developing cerebral infarction
    • Kato H, Kogure K: Biochemical and molecular characteristics of the brain with developing cerebral infarction. Cell Mol Neurobiol 19:93-108, 1999.
    • (1999) Cell Mol Neurobiol , vol.19 , pp. 93-108
    • Kato, H.1    Kogure, K.2
  • 46
    • 0029991601 scopus 로고    scopus 로고
    • Intracisternal basic fibroblast growth factor (bFGF) enhances behavioral recovery following focal cerebral infarction in the rat
    • Kawamata T, Alexis NE, Dietrich WD, Finklestein SP: Intracisternal basic fibroblast growth factor (bFGF) enhances behavioral recovery following focal cerebral infarction in the rat. J Cereb Blood Flow Metab 16:542-547, 1996.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 542-547
    • Kawamata, T.1    Alexis, N.E.2    Dietrich, W.D.3    Finklestein, S.P.4
  • 47
    • 0030760175 scopus 로고    scopus 로고
    • Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction
    • Kawamata T, Dietrich WD, Schallert T, Gotts JE, Cocke RR, Benowitz LI, Finklestein SP: Intracisternal basic fibroblast growth factor enhances functional recovery and up-regulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction. Proc Natl Acad Sci U S A 94:8179-8184, 1997.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 8179-8184
    • Kawamata, T.1    Dietrich, W.D.2    Schallert, T.3    Gotts, J.E.4    Cocke, R.R.5    Benowitz, L.I.6    Finklestein, S.P.7
  • 50
    • 0031953601 scopus 로고    scopus 로고
    • Calcium in ischemic cell death
    • Kristian T, Siesjö BK: Calcium in ischemic cell death. Stroke 29:705-718, 1998.
    • (1998) Stroke , vol.29 , pp. 705-718
    • Kristian, T.1    Siesjö, B.K.2
  • 53
    • 0036386833 scopus 로고    scopus 로고
    • Role of VEGF in an experimental model of cortical micronecrosis
    • Lafuente JV, Bulnes S, Mitre B, Riese HH: Role of VEGF in an experimental model of cortical micronecrosis. Amino Acids 23:241-245, 2002.
    • (2002) Amino Acids , vol.23 , pp. 241-245
    • Lafuente, J.V.1    Bulnes, S.2    Mitre, B.3    Riese, H.H.4
  • 57
    • 0037081177 scopus 로고    scopus 로고
    • Cell proliferation and differentiation from ependymal, subependymal and choroid plexus cells in response to stroke in rats
    • Li Y, Chen J, Chopp M: Cell proliferation and differentiation from ependymal, subependymal and choroid plexus cells in response to stroke in rats. J Neurol Sci 193:137-146, 2002.
    • (2002) J Neurol Sci , vol.193 , pp. 137-146
    • Li, Y.1    Chen, J.2    Chopp, M.3
  • 58
    • 0035954362 scopus 로고    scopus 로고
    • Treatment of stroke in rat with intracarotid administration of marrow stromal cells
    • Li Y, Chen J, Wang L, Lu M, Chopp M: Treatment of stroke in rat with intracarotid administration of marrow stromal cells. Neurology 56:1666-1672, 2001.
    • (2001) Neurology , vol.56 , pp. 1666-1672
    • Li, Y.1    Chen, J.2    Wang, L.3    Lu, M.4    Chopp, M.5
  • 59
    • 0032189609 scopus 로고    scopus 로고
    • Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils
    • Liu J, Solway K, Messing RO, Sharp FR: Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils. J Neurosci 18:7768-7778, 1998.
    • (1998) J Neurosci , vol.18 , pp. 7768-7778
    • Liu, J.1    Solway, K.2    Messing, R.O.3    Sharp, F.R.4
  • 60
  • 61
    • 0031815223 scopus 로고    scopus 로고
    • Gene transfer of calbindin D28k cDNA via herpes simplex virus amplicon vector decreases cytoplasmic calcium ion response and enhances neuronal survival following glutamatergic challenge but not following cyanide
    • Meier TJ, Ho DY, Park TS, Sapolsky RM: Gene transfer of calbindin D28k cDNA via herpes simplex virus amplicon vector decreases cytoplasmic calcium ion response and enhances neuronal survival following glutamatergic challenge but not following cyanide. J Neurochem 71:1013-1023, 1998.
    • (1998) J Neurochem , vol.71 , pp. 1013-1023
    • Meier, T.J.1    Ho, D.Y.2    Park, T.S.3    Sapolsky, R.M.4
  • 62
    • 0030758690 scopus 로고    scopus 로고
    • Increased expression of calbindin D28k via herpes simplex virus amplicon vector decreases calcium ion mobilization and enhances neuronal survival after hypoglycemic challenge
    • Meier TJ, Ho DY, Sapolsky RM: Increased expression of calbindin D28k via herpes simplex virus amplicon vector decreases calcium ion mobilization and enhances neuronal survival after hypoglycemic challenge. J Neurochem 69:1039-1047, 1997.
    • (1997) J Neurochem , vol.69 , pp. 1039-1047
    • Meier, T.J.1    Ho, D.Y.2    Sapolsky, R.M.3
  • 63
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow
    • Mezey E, Chandross KJ, Harta G, Maki RA, McKercher SR: Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow. Science 290:1779-1782, 2000.
    • (2000) Science , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3    Maki, R.A.4    McKercher, S.R.5
  • 64
    • 0036715222 scopus 로고    scopus 로고
    • Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage
    • Modo M, Stroemer RP, Tang E, Patel S, Hodges H: Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage. Stroke 33:2270-2278, 2002.
    • (2002) Stroke , vol.33 , pp. 2270-2278
    • Modo, M.1    Stroemer, R.P.2    Tang, E.3    Patel, S.4    Hodges, H.5
  • 65
    • 0036129310 scopus 로고    scopus 로고
    • Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations
    • Morshead CM, Benveniste P, Iscove NN, van der Kooy D: Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat Med 8:268-273, 2002.
    • (2002) Nat Med , vol.8 , pp. 268-273
    • Morshead, C.M.1    Benveniste, P.2    Iscove, N.N.3    van der Kooy, D.4
  • 67
    • 0035149257 scopus 로고    scopus 로고
    • Control of glial immune function by neurons
    • Neumann H: Control of glial immune function by neurons. Glia 36:191-199, 2001.
    • (2001) Glia , vol.36 , pp. 191-199
    • Neumann, H.1
  • 68
    • 0028104679 scopus 로고
    • Cognitive deficits induced by global cerebral ischaemia: Relationship to brain damage and reversal by transplants
    • Nunn J, Hodges H: Cognitive deficits induced by global cerebral ischaemia: Relationship to brain damage and reversal by transplants. Behav Brain Res 65:1-31, 1994.
    • (1994) Behav Brain Res , vol.65 , pp. 1-31
    • Nunn, J.1    Hodges, H.2
  • 69
    • 0027767887 scopus 로고
    • Reparative strategies in the brain: Treatment strategies based on trophic factors and cell transfer techniques
    • Olson L: Reparative strategies in the brain: Treatment strategies based on trophic factors and cell transfer techniques. Acta Neurochir Suppl (Wien) 58:3-7, 1993.
    • (1993) Acta Neurochir Suppl (Wien) , vol.58 , pp. 3-7
    • Olson, L.1
  • 70
    • 0033800607 scopus 로고    scopus 로고
    • Inapparent hemodynamic insufficiency exacerbates ischemic damage in a rat microembolic stroke model
    • Omae T, Mayzel-Oreg O, Li F, Sotak CH, Fisher M: Inapparent hemodynamic insufficiency exacerbates ischemic damage in a rat microembolic stroke model. Stroke 31:2494-2499, 2000.
    • (2000) Stroke , vol.31 , pp. 2494-2499
    • Omae, T.1    Mayzel-Oreg, O.2    Li, F.3    Sotak, C.H.4    Fisher, M.5
  • 72
    • 0034564162 scopus 로고    scopus 로고
    • Transplantation of neural stem cells: Cellular and gene therapy for hypoxic-ischemic brain injury
    • Park KI: Transplantation of neural stem cells: Cellular and gene therapy for hypoxic-ischemic brain injury. Yonsei Med J 41:825-835, 2000.
    • (2000) Yonsei Med J , vol.41 , pp. 825-835
    • Park, K.I.1
  • 73
    • 0035906544 scopus 로고    scopus 로고
    • Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation-reperfusion period after acute transient global hypoxia-ischemia in the newborn piglet
    • Park WS, Chang YS, Lee M: Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation-reperfusion period after acute transient global hypoxia-ischemia in the newborn piglet. Brain Res 901:102-108, 2001.
    • (2001) Brain Res , vol.901 , pp. 102-108
    • Park, W.S.1    Chang, Y.S.2    Lee, M.3
  • 75
    • 0021613131 scopus 로고
    • Transplantation of embryonic brain tissue into the brain of adult rats after hypoxic hypoxia
    • Polezhaev LV, Alexandrova MA: Transplantation of embryonic brain tissue into the brain of adult rats after hypoxic hypoxia. J Hirnforsch 25:99-106, 1984.
    • (1984) J Hirnforsch , vol.25 , pp. 99-106
    • Polezhaev, L.V.1    Alexandrova, M.A.2
  • 78
    • 0035826914 scopus 로고    scopus 로고
    • Human neural stem cells improve cognitive function of aged brain
    • Qu T, Brannen CL, Kim HM, Sugaya K: Human neural stem cells improve cognitive function of aged brain. Neuroreport 12:1127-1132, 2001.
    • (2001) Neuroreport , vol.12 , pp. 1127-1132
    • Qu, T.1    Brannen, C.L.2    Kim, H.M.3    Sugaya, K.4
  • 81
    • 0019595809 scopus 로고
    • A model for the study of stroke using the rat: Surgical ligation of the middle cerebral artery in the rat
    • Robinson RG: A model for the study of stroke using the rat: Surgical ligation of the middle cerebral artery in the rat. Am J Pathol 104:103-105, 1981.
    • (1981) Am J Pathol , vol.104 , pp. 103-105
    • Robinson, R.G.1
  • 82
    • 0037410074 scopus 로고    scopus 로고
    • Interleukin-1 and neuronal injury: Mechanisms, modification, and therapeutic potential
    • Rothwell N: Interleukin-1 and neuronal injury: Mechanisms, modification, and therapeutic potential. Brain Behav Immun 17:152-157, 2003.
    • (2003) Brain Behav Immun , vol.17 , pp. 152-157
    • Rothwell, N.1
  • 83
    • 0034534995 scopus 로고    scopus 로고
    • Interleukin 1 in the brain: Biology, pathology and therapeutic target
    • Rothwell NJ, Luheshi GN: Interleukin 1 in the brain: Biology, pathology and therapeutic target. Trends Neurosci 23:618-625, 2000.
    • (2000) Trends Neurosci , vol.23 , pp. 618-625
    • Rothwell, N.J.1    Luheshi, G.N.2
  • 85
    • 0035906522 scopus 로고    scopus 로고
    • Neuroprotection with herpes simplex vectors expressing virally derived anti-apoptotic agents
    • Roy M, Hom J, Sapolsky RM: Neuroprotection with herpes simplex vectors expressing virally derived anti-apoptotic agents. Brain Res 901:12-22, 2001.
    • (2001) Brain Res , vol.901 , pp. 12-22
    • Roy, M.1    Hom, J.2    Sapolsky, R.M.3
  • 89
    • 85046166537 scopus 로고    scopus 로고
    • Neuronal xenotransplantation in Parkinson's disease
    • Schumacher JM, Isacson O: Neuronal xenotransplantation in Parkinson's disease. Nat Med 3:474-475, 1997.
    • (1997) Nat Med , vol.3 , pp. 474-475
    • Schumacher, J.M.1    Isacson, O.2
  • 90
    • 0031587271 scopus 로고    scopus 로고
    • Recovery of spatial learning by grafts of a conditionally immortalized hippocampal neuroepithelial cell line into the ischaemia-lesioned hippocampus
    • Sinden JD, Rashid-Doubell F, Kershaw TR, Nelson A, Chadwick A, Jat PS, Noble MD, Hodges H, Gray JA: Recovery of spatial learning by grafts of a conditionally immortalized hippocampal neuroepithelial cell line into the ischaemia-lesioned hippocampus. Neuroscience 81:599-608, 1997.
    • (1997) Neuroscience , vol.81 , pp. 599-608
    • Sinden, J.D.1    Rashid-Doubell, F.2    Kershaw, T.R.3    Nelson, A.4    Chadwick, A.5    Jat, P.S.6    Noble, M.D.7    Hodges, H.8    Gray, J.A.9
  • 92
    • 0026501444 scopus 로고    scopus 로고
    • 90a. Snyder EY, Deitcher DL, Walsh C, Arnold-Aldea S, Hartwieg EA, Cepko CL: Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 68:33-51, 1992.
    • 90a. Snyder EY, Deitcher DL, Walsh C, Arnold-Aldea S, Hartwieg EA, Cepko CL: Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 68:33-51, 1992.
  • 93
    • 0029867899 scopus 로고    scopus 로고
    • Fetal neocortical tissue blocks implanted in brain infarcts of adult rats interconnect with the host brain
    • Sorensen JC, Grabowski M, Zimmer J, Johansson BB: Fetal neocortical tissue blocks implanted in brain infarcts of adult rats interconnect with the host brain. Exp Neurol 138:227-235, 1996.
    • (1996) Exp Neurol , vol.138 , pp. 227-235
    • Sorensen, J.C.1    Grabowski, M.2    Zimmer, J.3    Johansson, B.B.4
  • 94
    • 0034820606 scopus 로고    scopus 로고
    • Toti-/pluripotential stem cells and epigenetic modifications
    • Tada T, Tada M: Toti-/pluripotential stem cells and epigenetic modifications. Cell Struct Funct 26:149-160, 2001.
    • (2001) Cell Struct Funct , vol.26 , pp. 149-160
    • Tada, T.1    Tada, M.2
  • 95
    • 0033549246 scopus 로고    scopus 로고
    • Proliferation of neuronal precursor cells in the dentate gyrus is accelerated after transient forebrain ischemia in mice
    • Takagi Y, Nozaki K, Takahashi J, Yodoi J, Ishikawa M, Hashimoto N: Proliferation of neuronal precursor cells in the dentate gyrus is accelerated after transient forebrain ischemia in mice. Brain Res 831:283-287, 1999.
    • (1999) Brain Res , vol.831 , pp. 283-287
    • Takagi, Y.1    Nozaki, K.2    Takahashi, J.3    Yodoi, J.4    Ishikawa, M.5    Hashimoto, N.6
  • 96
    • 0034872480 scopus 로고    scopus 로고
    • Implantation of xenografts into the parkinsonian rat brain after portal venous administration of xenogeneic donor spleen cells
    • Takeuchi H, Yoshikawa M, Kanda S, Nonaka M, Nishimura F, Yamada T, Ishizaka S, Sakaki T: Implantation of xenografts into the parkinsonian rat brain after portal venous administration of xenogeneic donor spleen cells. J Neurosurg 94:775-781, 2001.
    • (2001) J Neurosurg , vol.94 , pp. 775-781
    • Takeuchi, H.1    Yoshikawa, M.2    Kanda, S.3    Nonaka, M.4    Nishimura, F.5    Yamada, T.6    Ishizaka, S.7    Sakaki, T.8
  • 97
    • 0019868418 scopus 로고
    • Focal cerebral ischaemia in the rat: Part 1 - Description of technique and early neuropathological consequences following middle cerebral artery occlusion
    • Tamura A, Graham DI, McCulloch J, Teasdale GM: Focal cerebral ischaemia in the rat: Part 1 - Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1:53-60, 1981.
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 53-60
    • Tamura, A.1    Graham, D.I.2    McCulloch, J.3    Teasdale, G.M.4
  • 98
    • 0019796754 scopus 로고
    • Focal cerebral ischaemia in the rat: Part 2 - Regional cerebral blood flow determined by [14C]iodoantipyrine autoradiography following middle cerebral artery occlusion
    • Tamura A, Graham DI, McCulloch J, Teasdale GM: Focal cerebral ischaemia in the rat: Part 2 - Regional cerebral blood flow determined by [14C]iodoantipyrine autoradiography following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1:61-69, 1981.
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 61-69
    • Tamura, A.1    Graham, D.I.2    McCulloch, J.3    Teasdale, G.M.4
  • 99
    • 0035499887 scopus 로고    scopus 로고
    • The development of neural stem cells
    • Temple S: The development of neural stem cells. Nature 414:112-117, 2001.
    • (2001) Nature , vol.414 , pp. 112-117
    • Temple, S.1
  • 100
    • 0025534746 scopus 로고
    • Neural grafting to ischemic and excitotoxic, hippocampal lesions in the adult rat
    • Tonder N, Sorensen T, Johansen FF, Zimmer J: Neural grafting to ischemic and excitotoxic, hippocampal lesions in the adult rat. Acta Neurobiol Exp (Wars) 50:367-380, 1990.
    • (1990) Acta Neurobiol Exp (Wars) , vol.50 , pp. 367-380
    • Tonder, N.1    Sorensen, T.2    Johansen, F.F.3    Zimmer, J.4
  • 101
    • 0035070869 scopus 로고    scopus 로고
    • Resolution of stroke deficits following contralateral grafts of conditionally immortal neuroepithelial stem cells
    • Veizovic T, Beech JS, Stroemer RP, Watson WP, Hodges H: Resolution of stroke deficits following contralateral grafts of conditionally immortal neuroepithelial stem cells. Stroke 32:1012-1019, 2001.
    • (2001) Stroke , vol.32 , pp. 1012-1019
    • Veizovic, T.1    Beech, J.S.2    Stroemer, R.P.3    Watson, W.P.4    Hodges, H.5
  • 102
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • Wagers AJ, Sherwood RI, Christensen JL, Weissman IL: Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 297:2256-2259, 2002.
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.I.2    Christensen, J.L.3    Weissman, I.L.4
  • 103
    • 0035975027 scopus 로고    scopus 로고
    • An improved version of embolic model of brain ischemic injury in the rat
    • Wang CX, Yang T, Shuaib A: An improved version of embolic model of brain ischemic injury in the rat. J Neurosci Methods 109:147-151, 2001.
    • (2001) J Neurosci Methods , vol.109 , pp. 147-151
    • Wang, C.X.1    Yang, T.2    Shuaib, A.3
  • 104
    • 0021826450 scopus 로고
    • Induction of reproducible brain infarction by photochemically initiated thrombosis
    • Watson BD, Dietrich WD, Busto R, Wachtel MS, Ginsberg MD: Induction of reproducible brain infarction by photochemically initiated thrombosis. Ann Neurol 17:497-504, 1985.
    • (1985) Ann Neurol , vol.17 , pp. 497-504
    • Watson, B.D.1    Dietrich, W.D.2    Busto, R.3    Wachtel, M.S.4    Ginsberg, M.D.5
  • 106
    • 0036900638 scopus 로고    scopus 로고
    • Region-specific generation of cholinergic neurons from fetal human neural stem cells grafted in adult rat
    • Wu P, Tarasenko YI, Gu Y, Huang LY, Coggeshall RE, Yu Y: Region-specific generation of cholinergic neurons from fetal human neural stem cells grafted in adult rat. Nat Neurosci 5:1271-1278, 2002.
    • (2002) Nat Neurosci , vol.5 , pp. 1271-1278
    • Wu, P.1    Tarasenko, Y.I.2    Gu, Y.3    Huang, L.Y.4    Coggeshall, R.E.5    Yu, Y.6
  • 108
    • 0030899994 scopus 로고    scopus 로고
    • Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury
    • Yang GY, Zhao YI, Davidson BL, Betz AL: Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury. Brain Res 751:181-188, 1997.
    • (1997) Brain Res , vol.751 , pp. 181-188
    • Yang, G.Y.1    Zhao, Y.I.2    Davidson, B.L.3    Betz, A.L.4
  • 113
    • 0035200623 scopus 로고    scopus 로고
    • In vitro differentiation of transplantable neural precursors from human embryonic stem cells
    • Zhang SC, Wernig M, Duncan ID, Brustle O, Thomson JA: In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol 19:1129-1133, 2001.
    • (2001) Nat Biotechnol , vol.19 , pp. 1129-1133
    • Zhang, S.C.1    Wernig, M.2    Duncan, I.D.3    Brustle, O.4    Thomson, J.A.5
  • 114
    • 0037155051 scopus 로고    scopus 로고
    • Bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse
    • Zhang ZG, Zhang L, Jiang Q, Chopp M: Bone marrow-derived endothelial progenitor cells participate in cerebral neovascularization after focal cerebral ischemia in the adult mouse. Circ Res 90:284-288, 2002.
    • (2002) Circ Res , vol.90 , pp. 284-288
    • Zhang, Z.G.1    Zhang, L.2    Jiang, Q.3    Chopp, M.4
  • 115
    • 0036118625 scopus 로고    scopus 로고
    • Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    • Zhao LR, Duan WM, Reyes M, Keene CD, Verfaillie CM, Low WC: Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol 174:11-20, 2002.
    • (2002) Exp Neurol , vol.174 , pp. 11-20
    • Zhao, L.R.1    Duan, W.M.2    Reyes, M.3    Keene, C.D.4    Verfaillie, C.M.5    Low, W.C.6
  • 116
    • 0030933273 scopus 로고    scopus 로고
    • Cellular and molecular neurosurgery: Pathways from concept to reality - Part I: Target disorders and concept approaches to gene therapy of the central nervous system
    • Zlokovic BV, Apuzzo MLJ: Cellular and molecular neurosurgery: Pathways from concept to reality - Part I: Target disorders and concept approaches to gene therapy of the central nervous system. Neurosurgery 40:789-804, 1997.
    • (1997) Neurosurgery , vol.40 , pp. 789-804
    • Zlokovic, B.V.1    Apuzzo, M.L.J.2
  • 117
    • 0030937038 scopus 로고    scopus 로고
    • Cellular and molecular neurosurgery: Pathways from concept to reality - Part II: Vector systems and delivery methodologies for gene therapy of the central nervous system
    • Zlokovic BV, Apuzzo MLJ: Cellular and molecular neurosurgery: Pathways from concept to reality - Part II: Vector systems and delivery methodologies for gene therapy of the central nervous system. Neurosurgery 40:805-813, 1997.
    • (1997) Neurosurgery , vol.40 , pp. 805-813
    • Zlokovic, B.V.1    Apuzzo, M.L.J.2


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