Gene transfer of calbindin D(28k) cDNA via herpes simplex virus amplicon vector decreases cytoplasmic calcium ion response and enhances neuronal survival following glutamatergic challenge but not following cyanide

Journal of Neurochemistry

Volumn 71, Issue 3, 1998, Pages 1013-1023

  Meier, Timothy J ^a   Ho, Dora Y ^a,b   Park, Travis S ^a   Sapolsky, Robert M ^a  

^a STANFORD UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calbindin D(28k); Cytoplasmic Ca2+ concentration; Excitatory amino acid overstimulation; Gene therapy; Genetransfer; Herpes simplex virus amplicon vector; Neuronal survival

Indexed keywords

CALBINDIN; GLUTAMINE; SODIUM CYANIDE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL SURVIVAL; CONTROLLED STUDY; FETUS; GENE THERAPY; GENE TRANSFER; HERPES SIMPLEX VIRUS; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA; HERPES; SIMPLEXVIRUS;

EID: 0031815223     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71031013.x     Document Type: Article

References (51)

1. Abdel-Hamid K. M. and Baimbridge K. G. (1997) The effects of artificial-calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons. Neuroscience 81, 673-687.
2. Airaksinen M. S., Thoenen H., and Meyer M. (1997) Vulnerability of midbrain dopaminergic neurons in calbindin-D28k-deficient mice: lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice. Eur. J. Neurosci. 9, 120-127.
3. Baimbridge K. G., Celio M. R., and Rogers J. H. (1992) Calcium-binding proteins in the nervous system. Trends Neurosci. 15, 303-308.
4. Bandyopadhyay P. K., Wang C. and Lipton H. L. ( 1992) Cap-independent translation by the 5′ untranslated region of Theiler's murine encephalomyelitis virus. J. Virol. 66, 6249-6256.
5. Batini C., Guegan M., Palestini M., Thomasset M., and Vigot R. (1997) Upregulation of calbindin-D-28k immunoreactivity by excitatory amino acids. Arch. Ital. Biol. 135, 385-397.
6. Bondy S. C. and LeBel C. P. (1993 ) The relationship between excitotoxicity and oxidative stress in the central nervous system. Free Radic. Biol. Med. 14, 633-642.
7. Brorson J. R., Bleakman D., Gibbons S. J., and Miller R. J. (1991) The properties of intracellular calcium stores in cultured rat cerebellar neurons. J. Neurosci. 11, 4024-4043.
8. Choi D. W. (1985) Glutamate neurotoxicity in cortical cell culture is calcium dependent. Neurosci. Lett. 58, 293-297.
9. Dash R., Lawrence M., Ho D., and Sapolsky R. (1996) A herpes simplex virus vector overexpressing the glucose transporter gene protects the rat dentate gyrus from an antimetabolite toxin. Exp. Neurol. 137, 43-48.
10. DeLuca N. A., McCarthy A. M., and Schaffer P. A. (1985) Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J. Virol. 56, 558-570.
11. Dubinsky J. M. and Rothman S. M. (1991) Intracellular calcium concentrations during "chemical hypoxia" and excitotoxic neuronal injury. J. Neurosci. 11, 2545-2551.
12. Duchen M. R., Valdeolmillos M., O'Neill S. C., and Eisner D. A. (1990) Effects of metabolic blockade on the regulation of intracellular calcium in dissociated mouse sensory neurones. J. Physiol. (Lond.) 424, 411-426.
13. Federoff H. J., Bergold P., Williamson A., and During M. (1996) Glutamate receptor gene transfer studies with HSV vectors. (Abstr.) J. Neurochem. 66 (Suppl. 1 ), S56.
14. Fink D. J., DeLuca N. A., Goins W. F., and Glorioso J. C. (1996) Gene transfer to neurons using herpes simplex virus-based vectors. Annu. Rev. Neurosci. 19, 265-287.
15. Geller A. I., During M. J., Oh Y. J., Freese A., and O'Malley K. (1995) An HSV-1 vector expressing tyrosine hydroxylase causes production and release of L-dopa from cultured rat striatal cells. J. Neurochem. 64, 487-496.
16. 2+ stores in astrocytes: role of the plasmalemmal Na/Ca exchanger. Glia 16, 296-305.
17. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
18. Hartley D. M. and Choi D. W. (1989) Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture. J. Pharmacol. Exp. Ther. 250, 752-758.
19. Heizmann C. W. (1992) Calcium-binding proteins: basic concepts and clinical implications. Gen. Physiol. Biophys. 11, 411-425.
20. Ho D. Y. (1994) Amplicon-based herpes simplex virus vectors. Methods Cell Biol. 43, 191-210.
21. Ho D. Y., Mocarski E. S., and Sapolsky R. M. ( 1993) Altering central nervous system physiology with a defective herpes simplex virus vector expressing the glucose transporter gene. Proc. Natl. Acad. Sci. USA 90, 3655-3659.
22. Ho D. Y., Fink S. L., Lawrence M. S., Meier T. J., Saydam T. C., Dash R., and Sapolsky R. M. (1995a) Herpes simplex virus vector system: analysis of its in vivo and in vitro cytopathic effects. J. Neurosci. Methods 57, 205-215.
23. Ho D. Y., Saydam T. C., Fink S. L., Lawrence M. S., and Sapolsky R. M. (1995b) Defective herpes simplex virus vectors expressing the rat brain glucose transporter protect cultured neurons from necrotic insults. J. Neurochem. 65, 842-850.
24. Hunziker W. and Schrickel S. (1988) Rat brain calbindin D28: six domain structure and extensive amino acid homology with chicken calbindin D28. Mol. Endocrinol. 2, 465-473.
25. Hyrc K., Handran S. D., Rothman S. M., and Goldberg M. P. (1997) Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators. J. Neurosci. 17, 6669-6677.
26. Iacopino A. M. and Christakos S. (1990) Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases. Proc. Natl. Acad. Sci. USA 87, 4078-4082.
27. Kaplitt M. G. and Makimura H. (1997) Defective viral vectors as agents for gene transfer in the nervous system. J. Neurosci. Methods 71, 125-132.
28. Kocsis J. D., Rand M. N., Lankford K. L., and Waxman S. G. (1994) Intracellular calcium mobilization and neurite outgrowth in mammalian neurons. J. Neurobiol. 25, 252-264.
29. Lawrence M. S., Ho D. Y., Dash R., and Sapolsky R. M. (1995) Herpes simplex virus vectors overexpressing the glucose transporter gene protect against seizure-induced neuron loss. Proc. Natl. Acad. Sci. USA 92, 7247-7251.
30. Lawrence M. S., McLaughlin J. R., Sun G., Ho D. Y., McIntosh L., Kunis D. N., Sapolsky R. M., and Steinberg G. K. (1997) Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered following a stroke. J. Cereb. Blood Flow Metab. 17, 740-744.
31. Linnik M. D., Zahos P., Geschwind M. D., and Federoff H. J. (1994) Expression of Bcl-2 from a defective herpes simplex virus 1 vector limits neuronal death in stroke. Soc. Neurosci. Abstr. 20, 1479.
32. Maduh E. U., Borowitz J. L., and Isom G. E. (1990) Cyanide-induced alteration of cytosolic pH: involvement of cellular hydrogen ion handling processes. Toxicol. Appl. Pharmacol. 106, 201-208.
33. Mannan R. M., Leib D. A., and Pepose J. S. (1997) Herpes simplex virus vector-mediated in vivo gene transfer to the photoreceptor cell layer of the mouse retina. (Abstr.) Invest. Ophthalmol. Vis. Sci. 38 (Suppl.), S1133.
34. 2+ extrusion in protection against neuronal excitotoxicity. FASEB J. 3, 2519-2526.
35. 28k in cultured hippocampal neurons. Neuron 6, 41-51.
36. Meier T. J., Ho D. Y., and Sapolsky R. M. (1995) Gene transfer of calbindin D28k cDNA by HSV amplicon vector decreases calcium ion mobilization following glutamate exposure but does not enhance cell survival. Soc. Neurosci. Abstr. 21, 609.
37. 28k via herpes simplex virus amplicon vector decreases calcium ion mobilization and enhances neuronal survival after hypoglycemic challenge. J. Neurochem. 69, 1039-1047.
38. 2+ buffering in rat hippocampal neurones. Neuropharmacology 34, 1123-1132.
39. Möckel V. and Fischer G. (1994) Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D28K. Brain Res. 648, 109-120.
40. Morgan R. A., Couture L., Elroy-Stein O., Ragheb J., Moss B., and Anderson W. F. (1992) Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy. Nucleic Acids Res. 20, 1293-1299.
41. Ng M. C., Iacopino A. M., Quintero E. M., Marches F., Sonsalla P. K., Liang C. L., Speciale S. G., and German D. C. (1996) The neurotoxin MPTP increases calbindin-D-28k levels in mouse midbrain dopaminergic neurons. Brain Res. Mol. Brain Res. 36, 329-336.
42. Okamoto M., Matsumoto M., Ohtsuki T., Taguchi A., Mikoshiba K., Yanagihara T., and Kamada T. (1993) Internucleosomal DNA cleavage involved in ischemia-induced neuronal death. Biochem. Biophys. Res. Commun. 196, 1356-1362.
43. Orrenius S., and Nicotera P. (1987) On the role of calcium in chemical toxicity. Arch. Toxicol. Suppl. 11, 11-19.
44. Orrenius S. and Nicotera P. (1994) The calcium ion and cell death. J. Neural Transm. Suppl. 43, 1-11.
45. Roberts-Lewis J. M., Marcy V. R., Zhao Y., Vaught J. L., Siman R., and Lewis M. E. (1993) Aurintricarboxylic acid protects hippocampal neurons from NMDA- and ischemia-induced toxicity in vivo. J. Neurochem. 61, 378-381.
46. Rothman S. M., Thurston J. H., and Hauhart R. E. (1987) Delayed neurotoxicity of excitatory amino acids in vitro. Neuroscience 22, 471-480.
47. Segal M. (1995) Imaging of calcium variations in living dendritic spines of cultured rat hippocampal neurons. J. Physiol. (Lond.) 486, 283-295.
48. Siman R., Noszek J. C., and Kegerise C. (1988) Role of calpain activation in the mechanism of excitatory amino acid neurotoxicity. Soc. Neurosci. Abstr. 14, 746.
49. Siman R., Noszek J. C., and Kegerise C. (1989) Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage. J. Neurosci. 9, 1579-1590.
50. Smith R. L., Geller A. I., Escudero K. W., and Wilcox C. L. (1995) Long-term expression in sensory neurons in tissue culture from herpes simplex virus type 1 (HSV-1) promoters in an HSV-1-derived vector. J. Virol. 69, 4593-4599.
51. Wood C. R., Morris G. E., Alderman E. M., Fouser L., and Kaufman R. J. (1991) An internal ribosome binding site can be used to select for homologous recombinants at an immunoglobulin heavy-chain locus. Proc. Natl. Acad. Sci. USA 88, 8006-8010.