Differentiation and histological analysis of embryonic stem cell-derived neural transplants in mice

Brain Pathology

Volumn 10, Issue 3, 2000, Pages 330-341

  Benninger, Yves ^a   Marino, Silvia ^b   Hardegger, Roland ^a   Weissmann, Charles ^c   Aguzzi, Adriano ^a   Brandner, Sebastian ^a,d  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIC FACTOR;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CELL; BRAIN TRANSPLANTATION; CELL DIFFERENTIATION; CULTURE MEDIUM; EMBRYO; FEMALE; GENE EXPRESSION; GENE TRANSFER; GENETIC MARKER; GRAFT REJECTION; GRAFT SURVIVAL; HISTOLOGY; MALE; MICROGLIA; MOUSE; NONHUMAN; OLIGODENDROGLIA; STEM CELL TRANSPLANTATION;

EID: 0033916716     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2000.tb00265.x     Document Type: Article

References (41)

1. Axelrod HR (1984) Embryonic stem cell lines derived from blastocysts by a simplified technique. Dev Biol 101: 225-228
2. Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI (1995) Embryonic stem cells express neuronal properties in vitro. Dev Biol 168: 342-357
3. Bain G, Ray WJ, Yao M, Gottlieb DI (1996) Retinoic acid promotes neural and represses mesodermal gene expression in mouse embryonic stem cells in culture. Biochem Biophys Res Commun 223: 691-694
4. Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL (1999) Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 283: 534-537
5. Bottenstein JE (1985) Cell Culture ion Neurosciences. In: Bottenstein JE, Harvey, A.L. (ed) Cell Culture ion Neurosciences. Plenum Press, New York, Landon, pp 3
6. Brewer GJ, Torricelli JR, Evege EK, Price PJ (1993) Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res 35: 567-576
7. Brüstle O (1999) Building brains: neural chimeras in the study of nervous system development and repair. Brain Pathol 9: 527-545
8. Brüstle O, Jones KN, Learish RD, Karram K, Choudhary K, Wiestler OD, Duncan ID, McKay RD (1999) Embryonic stem cell-derived glial precursors: A source of myelinating transplants. Science 285: 754-6
9. Brüstle O, Maskos U, McKay RD (1995) Host-guided migration allows targeted introduction of neurons into the embryonic brain. Neuron 15: 1275-1285
10. Brüstle O, McKay RD (1996) Neuronal progenitors as tools for cell replacement in the nervous system. Curr Opin Neurobiol 6: 688-695
11. Brüstle O, Spiro AC, Karram K, Choudhary K, Okabe S, McKay RD (1997) In vitro-generated neural precursors participate in mammalian brain development. Proc Natl Acad Sci USA 94: 14809-14814
12. Castro-Obregon S, Covarrubias L (1996) Role of retinoic acid and oxidative stress in embryonic stem cell death and neuronal differentiation. FEBS Lett 381: 93-97
13. Deacon T, Dinsmore J, Costantini LC, Ratliff J, Isacson O (1998) Blastula-stage stem cells can differentiate into dopaminergic and serotonergic neurons after transplantation. Exp Neurol 149: 28-41
14. Dinsmore J, Ratliff J, Deacon T, Pakzaban P, Jacoby D, Galpern W, Isacson O (1996) Embryonic stem cells differentiated in vitro as a novel source of cells for transplantation. Cell Transplants 5: 131-143
15. Friedrich G, Soriano P (1991) Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5: 1513-1523
16. Hardy RJ, Friedrich VL, Jr. (1996) Oligodendrocyte progenitors are generated throughout the embryonic mouse brain, but differentiate in restricted foci. Development 122: 2059-2069
17. Isenmann S, Brandner S, Kuhne G, Boner J, Aguzzi A (1996) Comparative in vivo and pathological analysis of the blood-brain barrier in mouse telencephalic transplants. Neuropathol Appl Neurobiol 22: 118-128
18. Isenmann S, Brandner S, Sure U, Aguzzi A (1996) Telencephalic transplants in mice: characterization of growth and differentiation patterns. Neuropathol Appl Neurobiol 22: 108-117
19. Kalcheim C, Barde YA, Thoenen H, Le Douarin NM (1987) In vivo effect of brain-derived neurotrophic factor on the survival of developing dorsal root ganglion cells. Embo J 6: 2871-2873
20. Koutouzis TK, Emerich DF, Borlongan CV, Freeman TB, Cahill DW, Sanberg PR (1994) Cell transplantation for central nervous system disorders. Crit Rev Neurobiol 8: 125-162
21. Lachyankar MB, Condon PJ, Quesenberry PJ, Litofsky NS, Recht LD, Ross AH (1997) Embryonic precursor cells that express Trk receptors: induction of different cell fates by NGF, BDNF, NT-3, and CNTF. Exp Neurol 144: 350-360
22. Lindvall O, Bjorklund A (1989) Transplantation strategies in the treatment of Parkinson's disease: experimental basis and clinical trials. Acta Neurol Scand Suppl 126: 197-210
23. Marino S, Kretschmer C, Brandner S, Cavard C, Zider A, Briand P, Isenmann S, Wagner EF, Aguzzi A (1995) Activation of HIV transcription by human foamy virus in transgenic mice. Lab Invest 73: 103-110
24. Martinez Serrano A, Fischer W, Soderstrom S, Ebendal T, Bjorklund A (1996) Long-term functional recovery from age-induced spatial memory impairments by nerve growth factor gene transfer to the rat basal forebrain. Proc Natl Acad Sci USA 93: 6355-6360
25. McDonald JW, Liu XZ, Qu Y, Liu S, Mickey SK, Turetsky D, Gottlieb DI, Choi DW (1999) Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat Med 5: 1410-1412
26. Milner RJ, Lai C, Nave KA, Lenoir D, Ogata J, Sutcliffe JG (1985) Nucleotide sequences of two mRNAs for rat brain myelin proteolipid protein. Cell 42: 931-939
27. Paulin D, Jakob H, Jacob F, Weber K, Osborn M (1982) In vitro differentiation of mouse teratocarcinoma cells monitored by intermediate filament expression. Differentiation 22: 90-99
28. Ridet JL, Privat A (1995) Gene therapy in the central nervous system: direct versus indirect gene delivery. J Neurosci Res 42: 287-293
29. Robertson EJ (1987) Teratocarcinomas and embryonic stem cells - a practical approach. In: D R and BD H (eds) Practical approach series. IRL Press, Oxford, vol 1
30. Rohrer DC, Nilaver G, Nipper V, Machida CA (1996) Genetically modified PC12 brain grafts: survivability and inducible nerve growth factor expression. Cell Transplant 5: 57-68
31. Rosenstein JM (1995) Why do neural transplants survive? An examination of some metabolic and pathophysiological considerations in neural transplantation. Exp Neurol 133: 1-6
32. Sabate O, Horellou P, Vigne E, Colin P, Perricaudet M, Buc Caron MH, Mallet J (1995) Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses. Nat Genet 9: 256-260
33. Soriano P (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain [letter]. Nat Genet 21: 70-71
34. Spector DL, D. GR, L.A. L (1998) Culture and biochemical analysis of cells. Cold Spring Harbour Laboratory Press
35. Strubing C, Ahnert-Hilger G, Shan J, Wiedenmann B, Hescheler J, Wobus AM (1995) Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons. Mech Dev 53: 275-287
36. Takahashi J, Palmer TD, Gage FH (1999) Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J Neurobiol 38: 65-81
37. Tsuda M, Yuasa S, Fujino Y, Sekikawa M, Ono K, Tsuchiya T, Kawamura K (1990) Retrovirus-mediated gene transfer into mouse cerebellar primary culture and its application to the neural transplantation. Brain Res Bull 24: 787-792
38. van Esseveldt KE, Liu R, Hermens WT, Verhaagen J, Boer GJ (1997) Adenoviral vector-mediated gene transfer and neurotransplantation: possibilities and limitations in grafting of the fetal rat suprachiasmatic nucleus. J Neurosci Methods 71: 113-23
39. Wobus AM, Grosse R, Schoneich J (1988) Specific effects of nerve growth factor on the differentiation pattern of mouse embryonic stem cells in vitro. Biomed Biochim Acta 47: 965-973
40. Yao M, Bain G, Gottlieb DI (1995) Neuronal differentiation of P19 embryonal carcinoma cells in defined media. J Neurosci Res 41: 792-804
41. Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P (1997) Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci USA 94: 3789-3794