Raisins and walking alter appetite hormones and plasma lipids by modifications in lipoprotein metabolism and up-regulation of the low-density lipoprotein receptor

Metabolism: Clinical and Experimental

Volumn 58, Issue 1, 2009, Pages 120-128

  Puglisi, Michael J ^a   Mutungi, Gisella ^a   Brun, Pierre J ^a   McGrane, Mary M ^a   Labonte, Cherise ^a   Volek, Jeff S ^a   Fernandez, Maria Luz ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; APOLIPOPROTEIN C2; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; CHOLESTEROL ESTER TRANSFER PROTEIN; GHRELIN; GLUCAGON LIKE PEPTIDE 1; HORMONE; LEPTIN; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PEPTIDE YY;

ADULT; AGED; ARTICLE; BODY WEIGHT; CALORIC INTAKE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIETARY FIBER; DIETARY INTAKE; FEMALE; GRAPE; HORMONE BLOOD LEVEL; HUMAN; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN METABOLISM; MALE; PRIORITY JOURNAL; RAISIN; RANDOMIZED CONTROLLED TRIAL; RECEPTOR UPREGULATION; WALKING;

AGED; APOLIPOPROTEINS; CARDIOVASCULAR DISEASES; CHOLESTEROL ESTER TRANSFER PROTEINS; FEMALE; GHRELIN; GLUCAGON-LIKE PEPTIDE 1; HUMANS; LEPTIN; LIPOPROTEINS; MALE; MIDDLE AGED; PEPTIDE YY; RECEPTORS, LDL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION; VITIS; WALKING;

EID: 57049087542     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2008.08.014     Document Type: Article

References (70)

1. Prevalence of heart disease-United States, 2005. MMWR Morb Mortal Wkly Rep 56 (2007) 113-118
2. Dauchet L., Amouyel P., Hercberg S., and Dallongeville J. Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. J Nutr 136 (2006) 2588-2593
3. Shrestha S., Freake H.C., McGrane M.M., Volek J.S., and Fernandez M.L. A combination of psyllium and plant sterols alters lipoprotein metabolism in hypercholesterolemic subjects by modifying the intravascular processing of lipoproteins and increasing LDL uptake. J Nutr 137 (2007) 1165-1170
4. Fernandez M.L. Distinct mechanisms of plasma LDL lowering by dietary fiber in the guinea pig: specific effects of pectin, guar gum, and psyllium. J Lipid Res 36 (1995) 2394-2404
5. Duncan K.H., Bacon J.A., and Weinsier R.L. The effects of high and low energy density diets on satiety, energy intake, and eating time of obese and nonobese subjects. Am J Clin Nutr 37 (1983) 763-767
6. Burton-Freeman B. Dietary fiber and energy regulation. J Nutr 130 (2000) 272S-275S
7. Zern T.L., and Fernandez M.L. Cardioprotective effects of dietary polyphenols. J Nutr 135 (2005) 2291-2294
8. Zern T.L., West K.L., and Fernandez M.L. Grape polyphenols decrease plasma triglycerides and cholesterol accumulation in the aorta of ovariectomized guinea pigs. J Nutr 133 (2003) 2268-2272
9. Wei C., Penumetcha M., Santanam N., Liu Y.G., Garelnabi M., and Parthasarathy S. Exercise might favor reverse cholesterol transport and lipoprotein clearance: potential mechanism for its anti-atherosclerotic effects. Biochim Biophys Acta 1723 (2005) 124-127
10. Vinagre C.G., Ficker E.S., Finazzo C., Alves M.J., de Angelis K., Irigoyen M.C., et al. Enhanced removal from the plasma of LDL-like nanoemulsion cholesteryl ester in trained men compared with sedentary healthy men. J Appl Physiol 103 (2007) 1166-1171
11. Considine R.V. Regulation of leptin production. Rev Endocr Metab Disord 2 (2001) 357-363
12. Mueller W.M., Gregoire F.M., Stanhope K.L., Mobbs C.V., Mizuno T.M., Warden C.H., et al. Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology 139 (1998) 551-558
13. Jenkins A.B., Markovic T.P., Fleury A., and Campbell L.V. Carbohydrate intake and short-term regulation of leptin in humans. Diabetologia 40 (1997) 348-351
14. Kojima M., and Kangawa K. Ghrelin, an orexigenic signaling molecule from the gastrointestinal tract. Curr Opin Pharmacol 2 (2002) 665-668
15. Gruendel S., Garcia A.L., Otto B., Mueller C., Steiniger J., Weickert M.O., et al. Carob pulp preparation rich in insoluble dietary fiber and polyphenols enhances lipid oxidation and lowers postprandial acylated ghrelin in humans. J Nutr 136 (2006) 1533-1538
16. Weigle D.S., Cummings D.E., Newby P.D., Breen P.A., Frayo R.S., Matthys C.C., et al. Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet. J Clin Endocrinol Metab 88 (2003) 1577-1586
17. Martins C., Morgan L.M., Bloom S.R., and Robertson M.D. Effects of exercise on gut peptides, energy intake and appetite. J Endocrinol 193 (2007) 251-258
18. Schmidt A., Maier C., Schaller G., Nowotny P., Bayerle-Eder M., Buranyi B., et al. Acute exercise has no effect on ghrelin plasma concentrations. Horm Metab Res 36 (2004) 174-177
19. Burns S.F., Broom D.R., Miyashita M., Mundy C., and Stensel D.J. A single session of treadmill running has no effect on plasma total ghrelin concentrations. J Sports Sci 25 (2007) 635-642
20. Gee J.M., Lee-Finglas W., Wortley G.W., and Johnson I.T. Fermentable carbohydrates elevate plasma enteroglucagon but high viscosity is also necessary to stimulate small bowel mucosal cell proliferation in rats. J Nutr 126 (1996) 373-379
21. Reimer R.A., and McBurney M.I. Dietary fiber modulates intestinal proglucagon messenger ribonucleic acid and postprandial secretion of glucagon-like peptide-1 and insulin in rats. Endocrinology 137 (1996) 3948-3956
22. Adam T.C., and Westerterp-Plantenga M.S. Glucagon-like peptide-1 release and satiety after a nutrient challenge in normal-weight and obese subjects. Br J Nutr 93 (2005) 845-851
23. Adam T.C., and Westerterp-Plantenga M.S. Nutrient-stimulated GLP-1 release in normal-weight men and women. Horm Metab Res 37 (2005) 111-117
24. Gutzwiller J.P., Goke B., Drewe J., Hildebrand P., Ketterer S., Handschin D., et al. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut 44 (1999) 81-86
25. Schirra J., Katschinski M., Weidmann C., Schafer T., Wank U., Arnold R., et al. Gastric emptying and release of incretin hormones after glucose ingestion in humans. J Clin Invest 97 (1996) 92-103
26. Schirra J., Kuwert P., Wank U., Leicht P., Arnold R., Goke B., et al. Differential effects of subcutaneous GLP-1 on gastric emptying, antroduodenal motility, and pancreatic function in men. Proc Assoc Am Physicians 109 (1997) 84-97
27. Ali-Rachedi A., Varndell I.M., Adrian T.E., Gapp D.A., Van Noorden S., Bloom S.R., et al. Peptide YY (PYY) immunoreactivity is co-stored with glucagon-related immunoreactants in endocrine cells of the gut and pancreas. Histochemistry 80 (1984) 487-491
28. El-Salhy M., Grimelius L., Wilander E., Ryberg B., Terenius L., Lundberg J.M., et al. Immunocytochemical identification of polypeptide YY (PYY) cells in the human gastrointestinal tract. Histochemistry 77 (1983) 15-23
29. Perez-Tilve D., Nogueiras R., Mallo F., Benoit S.C., and Tschoep M. Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy balance [corrected] and metabolism. Endocrine 29 (2006) 61-71
30. Challis B.G., Pinnock S.B., Coll A.P., Carter R.N., Dickson S.L., and O'Rahilly S. Acute effects of PYY3-36 on food intake and hypothalamic neuropeptide expression in the mouse. Biochem Biophys Res Commun 311 (2003) 915-919
31. Halatchev I.G., and Cone R.D. Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice. Cell Metab 1 (2005) 159-168
32. Pappas T.N., Debas H.T., and Taylor I.L. Peptide YY: metabolism and effect on pancreatic secretion in dogs. Gastroenterology 89 (1985) 1387-1392
33. Parker T.L., Wang X.H., Pazmino J., and Engeseth N.J. Antioxidant capacity and phenolic content of grapes, sun-dried raisins, and golden raisins and their effect on ex vivo serum antioxidant capacity. J Agric Food Chem 55 (2007) 8472-8477
34. Loaiza J., Murano E., and Cisneros-Zavallos L. Analysis of raisin extracts to determine phenolic content and antimicrobial activity (2001), IFT, New Orleans
35. Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl 97 (1968) 77-89
36. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
37. Barber R.D., Harmer D.W., Coleman R.A., and Clark B.J. GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues. Physiol Genomics 21 (2005) 389-395
38. Liu M.Y., Xydakis A.M., Hoogeveen R.C., Jones P.H., Smith E.O., Nelson K.W., et al. Multiplexed analysis of biomarkers related to obesity and the metabolic syndrome in human plasma, using the Luminex-100 system. Clin Chem 51 (2005) 1102-1109
39. Puglisi M.J., Vaishnav U., Shrestha S., Torres-Gonzalez M., Wood R.J., Volek J.S., et al. Raisins and additional walking have distinct effects on plasma lipids and inflammatory cytokines. Lipids Health Dis 7 (2008) 14
40. Powell E.E., and Kroon P.A. Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver. J Clin Invest 93 (1994) 2168-2174
41. Roach P.D., Kerry N.L., Whiting M.J., and Nestel P.J. Coordinate changes in the low density lipoprotein receptor activity of liver and mononuclear cells in the rabbit. Atherosclerosis 101 (1993) 157-164
42. Camire M.E., and Dougherty M.P. Raisin dietary fiber composition and in vitro bile acid binding. J Agric Food Chem 51 (2003) 834-837
43. Trautwein E.A., Kunath-Rau A., and Erbersdobler H.F. Increased fecal bile acid excretion and changes in the circulating bile acid pool are involved in the hypocholesterolemic and gallstone-preventive actions of psyllium in hamsters. J Nutr 129 (1999) 896-902
44. Fischer C.P., Hiscock N.J., Penkowa M., Basu S., Vessby B., Kallner A., et al. Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle. J Physiol 558 (2004) 633-645
45. Gierens H., Nauck M., Roth M., Schinker R., Schurmann C., Scharnagl H., et al. Interleukin-6 stimulates LDL receptor gene expression via activation of sterol-responsive and Sp1 binding elements. Arterioscler Thromb Vasc Biol 20 (2000) 1777-1783
46. Kawakami A., Aikawa M., Alcaide P., Luscinskas F.W., Libby P., and Sacks F.M. Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells. Circulation 114 (2006) 681-687
47. Otarod J.K., and Goldberg I.J. Lipoprotein lipase and its role in regulation of plasma lipoproteins and cardiac risk. Curr Atheroscler Rep 6 (2004) 335-342
48. Ito Y., Azrolan N., O'Connell A., Walsh A., and Breslow J.L. Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice. Science 249 (1990) 790-793
49. Lemieux I., Salomon H., and Despres J.P. Contribution of apo CIII reduction to the greater effect of 12-week micronized fenofibrate than atorvastatin therapy on triglyceride levels and LDL size in dyslipidemic patients. Ann Med 35 (2003) 442-448
50. Horowitz J.F., Leone T.C., Feng W., Kelly D.P., and Klein S. Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training. Am J Physiol Endocrinol Metab 279 (2000) E348-E355
51. Iemitsu M., Miyauchi T., Maeda S., Tanabe T., Takanashi M., Irukayama-Tomobe Y., et al. Aging-induced decrease in the PPAR-alpha level in hearts is improved by exercise training. Am J Physiol Heart Circ Physiol 283 (2002) H1750-H1760
52. Olivieri O., Martinelli N., Sandri M., Bassi A., Guarini P., Trabetti E., et al. Apolipoprotein C-III, n-3 polyunsaturated fatty acids, and "insulin-resistant" T-455C APOC3 gene polymorphism in heart disease patients: example of gene-diet interaction. Clin Chem 51 (2005) 360-367
53. Fruchart J.C., Duriez P., and Staels B. Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis. Curr Opin Lipidol 10 (1999) 245-257
54. Gill J.M., Al-Mamari A., Ferrell W.R., Cleland S.J., Sattar N., Packard C.J., et al. Effects of a moderate exercise session on postprandial lipoproteins, apolipoproteins and lipoprotein remnants in middle-aged men. Atherosclerosis 185 (2006) 87-96
55. Wellhoener P., Fruehwald-Schultes B., Kern W., Dantz D., Kerner W., Born J., et al. Glucose metabolism rather than insulin is a main determinant of leptin secretion in humans. J Clin Endocrinol Metab 85 (2000) 1267-1271
56. Marshall S. Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: a nutritional perspective of diabetes, obesity, and cancer. Sci STKE 2006 (2006) re7
57. Marshall S., Bacote V., and Traxinger R.R. Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem 266 (1991) 4706-4712
58. Wang J., Liu R., Hawkins M., Barzilai N., and Rossetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 393 (1998) 684-688
59. Considine R.V., Cooksey R.C., Williams L.B., Fawcett R.L., Zhang P., Ambrosius W.T., et al. Hexosamines regulate leptin production in human subcutaneous adipocytes. J Clin Endocrinol Metab 85 (2000) 3551-3556
60. Mason M.M., He Y., Chen H., Quon M.J., and Reitman M. Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor. Endocrinology 139 (1998) 1013-1022
61. Stephens T.W., Basinski M., Bristow P.K., Bue-Valleskey J.M., Burgett S.G., Craft L., et al. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377 (1995) 530-532
62. Schwartz M.W., Seeley R.J., Campfield L.A., Burn P., and Baskin D.G. Identification of targets of leptin action in rat hypothalamus. J Clin Invest 98 (1996) 1101-1106
63. El-Haschimi K., and Lehnert H. Leptin resistance-or why leptin fails to work in obesity. Exp Clin Endocrinol Diabetes 111 (2003) 2-7
64. Mohlig M., Koebnick C., Weickert M.O., Lueder W., Otto B., Steiniger J., et al. Arabinoxylan-enriched meal increases serum ghrelin levels in healthy humans. Horm Metab Res 37 (2005) 303-308
65. Weickert M.O., Spranger J., Holst J.J., Otto B., Koebnick C., Mohlig M., et al. Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety. Br J Nutr 96 (2006) 795-798
66. Schmitz K.H., Warren M., Rundle A.G., Williams N.I., Gross M.D., and Kurzer M.S. Exercise effect on oxidative stress is independent of change in estrogen metabolism. Cancer Epidemiol Biomarkers Prev 17 (2008) 220-223
67. Dube M.G., Beretta E., Dhillon H., Ueno N., Kalra P.S., and Kalra S.P. Central leptin gene therapy blocks high-fat diet-induced weight gain, hyperleptinemia, and hyperinsulinemia: increase in serum ghrelin levels. Diabetes 51 (2002) 1729-1736
68. Beretta E., Dube M.G., Kalra P.S., and Kalra S.P. Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: effects on serum ghrelin and appetite-regulating genes. Pediatr Res 52 (2002) 189-198
69. Keller P., Keller C., Steensberg A., Robinson L.E., and Pedersen B.K. Leptin gene expression and systemic levels in healthy men: effect of exercise, carbohydrate, interleukin-6, and epinephrine. J Appl Physiol 98 (2005) 1805-1812
70. Kraemer R.R., Durand R.J., Acevedo E.O., Johnson L.G., Kraemer G.R., Hebert E.P., et al. Rigorous running increases growth hormone and insulin-like growth factor-I without altering ghrelin. Exp Biol Med (Maywood) 229 (2004) 240-246