메뉴 건너뛰기




Volumn 20, Issue 7, 2000, Pages 1777-1783

Interleukin-6 stimulates LDL receptor gene expression via activation of sterol-responsive and Sp1 binding elements

Author keywords

Cholesterol; Hypocholesterolemia; Lipoproteins; Receptors; Transcription factors

Indexed keywords

INTERLEUKIN 6; ISOPROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN;

EID: 0033927969     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.20.7.1777     Document Type: Article
Times cited : (90)

References (35)
  • 1
    • 0027731546 scopus 로고
    • Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome
    • Casey LC, Balk RA, Bone RC. Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med. 1993;119:771-778
    • (1993) Ann Intern Med. , vol.119 , pp. 771-778
    • Casey, L.C.1    Balk, R.A.2    Bone, R.C.3
  • 3
    • 0027304960 scopus 로고
    • Myocardial injury: The acute phase response and lipoprotein metabolism
    • Rosenson RS. Myocardial injury: the acute phase response and lipoprotein metabolism. J Am Coll Cardiol. 1993;22:933-940.
    • (1993) J Am Coll Cardiol. , vol.22 , pp. 933-940
    • Rosenson, R.S.1
  • 5
    • 0031935347 scopus 로고    scopus 로고
    • Postsurgical reduction of serum lipoproteins: Interleukin-6 and the acute-phase response
    • Akgun S, Ertel NH, Mosenthal A, Oser W. Postsurgical reduction of serum lipoproteins: interleukin-6 and the acute-phase response. J Lab Clin Med. 1998;131:103-108.
    • (1998) J Lab Clin Med. , vol.131 , pp. 103-108
    • Akgun, S.1    Ertel, N.H.2    Mosenthal, A.3    Oser, W.4
  • 7
    • 0026013009 scopus 로고
    • Effects of recombinant human macrophage colony-stimulating factor on plasma cholesterol levels
    • Stoudemire JB, Garnick MB. Effects of recombinant human macrophage colony-stimulating factor on plasma cholesterol levels. Blood. 1991;77: 750-755.
    • (1991) Blood , vol.77 , pp. 750-755
    • Stoudemire, J.B.1    Garnick, M.B.2
  • 9
    • 0030894256 scopus 로고    scopus 로고
    • Inhibition of apolipoprotein B secretion by IL-6 is mediated by EGF or an EGF-like molecule in CaCo-2 cells
    • Murthy S, Mathur S, Bishop WP, Field EJ. Inhibition of apolipoprotein B secretion by IL-6 is mediated by EGF or an EGF-like molecule in CaCo-2 cells. J Lipid Res. 1997;38:206-216.
    • (1997) J Lipid Res. , vol.38 , pp. 206-216
    • Murthy, S.1    Mathur, S.2    Bishop, W.P.3    Field, E.J.4
  • 10
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science. 1986;232:34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 11
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature. 1990;343:425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 12
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown MS, Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 1997;89:331-340.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 13
    • 0023227574 scopus 로고
    • Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene
    • Sudhof TC, Van der Westhuyzen DR, Goldstein JL, Brown MS, Russell DW. Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene. J Biol Chem. 1987;262:10773-10779.
    • (1987) J Biol Chem. , vol.262 , pp. 10773-10779
    • Sudhof, T.C.1    Van Der Westhuyzen, D.R.2    Goldstein, J.L.3    Brown, M.S.4    Russell, D.W.5
  • 14
    • 0023867357 scopus 로고
    • Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1
    • Dawson PA, Hofmann SL, van der Westhuyzen DR, Sudhof TC, Brown MS, Goldstein JL. Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1. J Biol Chem. 1988;263:3372-3379.
    • (1988) J Biol Chem. , vol.263 , pp. 3372-3379
    • Dawson, P.A.1    Hofmann, S.L.2    Van Der Westhuyzen, D.R.3    Sudhof, T.C.4    Brown, M.S.5    Goldstein, J.L.6
  • 15
    • 0027490174 scopus 로고
    • SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
    • Yokoyama C, Wang X, Briggs MR, Admon A, Wu J, Hua X, Goldstein JL, Brown MS. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell. 1993;75:187-197.
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8
  • 16
    • 0027190308 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter, I: Identification of the protein and delineation of its target nucleotide sequence
    • Briggs MR, Yokoyama C, Wang X, Brown MS, Goldstein JL. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter, I: identification of the protein and delineation of its target nucleotide sequence. J Biol Chem. 1993;268:14490-14496.
    • (1993) J Biol Chem. , vol.268 , pp. 14490-14496
    • Briggs, M.R.1    Yokoyama, C.2    Wang, X.3    Brown, M.S.4    Goldstein, J.L.5
  • 17
    • 0028225462 scopus 로고
    • SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
    • Wang X, Sato R, Brown MS, Hua X, Goldstein JL. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis. Cell. 1994;77:53-62.
    • (1994) Cell , vol.77 , pp. 53-62
    • Wang, X.1    Sato, R.2    Brown, M.S.3    Hua, X.4    Goldstein, J.L.5
  • 18
    • 0028820299 scopus 로고
    • Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection
    • Hua X, Sakai J, Ho YK, Goldstein JL, Brown MS. Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection. J Biol Chem. 1995;270:29422-29427.
    • (1995) J Biol Chem. , vol.270 , pp. 29422-29427
    • Hua, X.1    Sakai, J.2    Ho, Y.K.3    Goldstein, J.L.4    Brown, M.S.5
  • 19
    • 0027197507 scopus 로고
    • Cytokine regulation of low density lipoprotein receptor gene transcription in HepG2 cells
    • Stopeck AT, Nicholson AC, Mancini FP, Hajjar DP. Cytokine regulation of low density lipoprotein receptor gene transcription in HepG2 cells. J Biol Chem. 1993;268:17489-17494.
    • (1993) J Biol Chem. , vol.268 , pp. 17489-17494
    • Stopeck, A.T.1    Nicholson, A.C.2    Mancini, F.P.3    Hajjar, D.P.4
  • 20
  • 21
    • 0029084805 scopus 로고
    • Interleukin-6 family of cytokines and gp130
    • Kishimoto T, Akira S, Narazaki M, Taga T. Interleukin-6 family of cytokines and gp130. Blood. 1995;86:1243-1254.
    • (1995) Blood , vol.86 , pp. 1243-1254
    • Kishimoto, T.1    Akira, S.2    Narazaki, M.3    Taga, T.4
  • 23
    • 0016241915 scopus 로고
    • Binding and degradation of low density lipoproteins by cultured human fibroblasts
    • Goldstein JL, Brown MS. Binding and degradation of low density lipoproteins by cultured human fibroblasts. J Biol Chem. 1974;249: 5153-5162.
    • (1974) J Biol Chem. , vol.249 , pp. 5153-5162
    • Goldstein, J.L.1    Brown, M.S.2
  • 24
    • 0020973547 scopus 로고
    • Receptor-mediated endocytosis of low-density lipoprotein in cultured cells
    • Goldstein JL, Basu SK, Brown MS. Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. Methods Enzymol. 1983;98: 241-260.
    • (1983) Methods Enzymol. , vol.98 , pp. 241-260
    • Goldstein, J.L.1    Basu, S.K.2    Brown, M.S.3
  • 25
    • 0027331369 scopus 로고
    • Accumulation of 'small dense' low density lipoproteins (LDL) in a homozygous patients with familial defective apolipoprotein B-100 results from heterogenous interaction of LDL subfractions with the LDL receptor
    • März W, Baumstark MW, Scharnagl H, Ruzicka V, Buxbaum S, Herwig J, Pohl T, Russ A, Schaaf L, Berg A, et al. Accumulation of 'small dense' low density lipoproteins (LDL) in a homozygous patients with familial defective apolipoprotein B-100 results from heterogenous interaction of LDL subfractions with the LDL receptor. J Clin Invest. 1993;92: 2922-2933.
    • (1993) J Clin Invest. , vol.92 , pp. 2922-2933
    • März, W.1    Baumstark, M.W.2    Scharnagl, H.3    Ruzicka, V.4    Buxbaum, S.5    Herwig, J.6    Pohl, T.7    Russ, A.8    Schaaf, L.9    Berg, A.10
  • 26
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts,' prepared from a small number of cells
    • Schreiber E, Matthias P, Muller MM, Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts,' prepared from a small number of cells. Nucleic Acids Res. 1989;17:6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 27
    • 0025239760 scopus 로고
    • Relation of growth- and sterol-related regulatory pathways for low density lipoprotein receptor gene expression
    • Mazzone T, Basheeruddin K, Ping L, Schick C. Relation of growth- and sterol-related regulatory pathways for low density lipoprotein receptor gene expression. J Biol Chem. 1990;265:5145-5149.
    • (1990) J Biol Chem. , vol.265 , pp. 5145-5149
    • Mazzone, T.1    Basheeruddin, K.2    Ping, L.3    Schick, C.4
  • 28
    • 0031552365 scopus 로고    scopus 로고
    • Structural and functional analyses of DNA bending induced by Sp1 family transcription factors
    • Sjottem E, Andersen C, Johansen T. Structural and functional analyses of DNA bending induced by Sp1 family transcription factors. J Mol Biol. 1997;267:490-504.
    • (1997) J Mol Biol. , vol.267 , pp. 490-504
    • Sjottem, E.1    Andersen, C.2    Johansen, T.3
  • 29
    • 0030273548 scopus 로고    scopus 로고
    • Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension
    • Testa M, Yeh M, Lee P, Fanelli R, Loperfido F, Berman JW, LeJemtel TH. Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension. J Am Coll Cardiol. 1996;28:964-971.
    • (1996) J Am Coll Cardiol. , vol.28 , pp. 964-971
    • Testa, M.1    Yeh, M.2    Lee, P.3    Fanelli, R.4    Loperfido, F.5    Berman, J.W.6    LeJemtel, T.H.7
  • 30
    • 0027129391 scopus 로고
    • Metabolic disturbances and wasting in the acquired immunodeficiency syndrome
    • Grunfeld C, Feingold KR. Metabolic disturbances and wasting in the acquired immunodeficiency syndrome. N Engl J Med. 1992;327: 329-337.
    • (1992) N Engl J Med. , vol.327 , pp. 329-337
    • Grunfeld, C.1    Feingold, K.R.2
  • 31
    • 0026497421 scopus 로고
    • Transforming growth factor-beta 1 and interleukin-1 beta stimulate LDL receptor activity in Hep G2 cells
    • Moorby CD, Gherardi E, Dovey L, Godliman C, Bowyer DE. Transforming growth factor-beta 1 and interleukin-1 beta stimulate LDL receptor activity in Hep G2 cells. Atherosclerosis. 1992;97:21-28.
    • (1992) Atherosclerosis , vol.97 , pp. 21-28
    • Moorby, C.D.1    Gherardi, E.2    Dovey, L.3    Godliman, C.4    Bowyer, D.E.5
  • 32
    • 0028353228 scopus 로고
    • Stimulation of low-density lipoprotein uptake in HepG2 cells by epidermal growth factor via a tyrosine kinase-dependent, but protein kinase C-independent, mechanism
    • Graham A, Russell LJ. Stimulation of low-density lipoprotein uptake in HepG2 cells by epidermal growth factor via a tyrosine kinase-dependent, but protein kinase C-independent, mechanism. Biochem J. 1994;298: 579-584.
    • (1994) Biochem J. , vol.298 , pp. 579-584
    • Graham, A.1    Russell, L.J.2
  • 33
    • 0029965098 scopus 로고    scopus 로고
    • SREBP-1 mediates activation of the low density lipoprotein receptor promoter by insulin and insulin-like growth factor-I
    • Streicher R, Kotzka J, Muller-Wieland D, Siemeister G, Munck M, Avci H, Krone W. SREBP-1 mediates activation of the low density lipoprotein receptor promoter by insulin and insulin-like growth factor-I. J Biol Chem. 1996;271:7128-7133.
    • (1996) J Biol Chem. , vol.271 , pp. 7128-7133
    • Streicher, R.1    Kotzka, J.2    Muller-Wieland, D.3    Siemeister, G.4    Munck, M.5    Avci, H.6    Krone, W.7
  • 34
    • 0028799622 scopus 로고
    • Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene
    • Sanchez HB, Yieh L, Osborne TF. Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene. J Biol Chem. 1995;270:1161-1169.
    • (1995) J Biol Chem. , vol.270 , pp. 1161-1169
    • Sanchez, H.B.1    Yieh, L.2    Osborne, T.F.3
  • 35
    • 0033525856 scopus 로고    scopus 로고
    • Induction of low density lipoprotein receptor (LDLR) transcription by oncostatin M is mediated by the extracellular signal-regulated kinase signaling pathway and the repeat 3 element of the LDLR promoter
    • Li C, Kraemer FB, Ahlborn TE, Liu J. Induction of low density lipoprotein receptor (LDLR) transcription by oncostatin M is mediated by the extracellular signal-regulated kinase signaling pathway and the repeat 3 element of the LDLR promoter. J Biol Chem. 1999;274:6747-6753.
    • (1999) J Biol Chem. , vol.274 , pp. 6747-6753
    • Li, C.1    Kraemer, F.B.2    Ahlborn, T.E.3    Liu, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.