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Volumn 137, Issue 5, 2007, Pages 1165-1170

A combination of psyllium and plant sterols alters lipoprotein metabolism in hypercholesterolemic subjects by modifying the intravascular processing of lipoproteins and increasing LDL uptake

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; ISPAGULA; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PHYTOSTEROL; PLACEBO;

EID: 34247881801     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/137.5.1165     Document Type: Article
Times cited : (37)

References (47)
  • 1
    • 0035897696 scopus 로고    scopus 로고
    • Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    • Expert Panel on Detection
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285:2486-97.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 2
    • 33644693174 scopus 로고    scopus 로고
    • New results in the management of hypercholesterolemia
    • Sarman B. New results in the management of hypercholesterolemia. Orv Hetil. 2005;146:1999-2004.
    • (2005) Orv Hetil , vol.146 , pp. 1999-2004
    • Sarman, B.1
  • 4
    • 0029823744 scopus 로고    scopus 로고
    • Predominance of dense low-density lipoprotein particles predicts angiographic benefit of therapy in the Stanford Coronary Risk Intervention Project
    • Miller BD, Alderman EL, Haskell WL, Fair JM, Krauss RM. Predominance of dense low-density lipoprotein particles predicts angiographic benefit of therapy in the Stanford Coronary Risk Intervention Project. Circulation. 1996;94:2146-53.
    • (1996) Circulation , vol.94 , pp. 2146-2153
    • Miller, B.D.1    Alderman, E.L.2    Haskell, W.L.3    Fair, J.M.4    Krauss, R.M.5
  • 5
    • 0035818513 scopus 로고    scopus 로고
    • Comparison of various electrophoretic characteristics of LDL particles and their relationship to the risk of ischemic heart disease
    • St Pierre AC, Ruel IL, Cantin B, Dagenais GR, Bernand PM, Depres JP, Lamarche B. Comparison of various electrophoretic characteristics of LDL particles and their relationship to the risk of ischemic heart disease. Circulation. 2001;104:2295-9.
    • (2001) Circulation , vol.104 , pp. 2295-2299
    • St Pierre, A.C.1    Ruel, I.L.2    Cantin, B.3    Dagenais, G.R.4    Bernand, P.M.5    Depres, J.P.6    Lamarche, B.7
  • 6
    • 0020060090 scopus 로고
    • Identification of multiple subclasses of plasma low density lipoproteins in normal humans
    • Krauss RM, Burke DJ. Identification of multiple subclasses of plasma low density lipoproteins in normal humans. J Lipid Res. 1982;23:97-104.
    • (1982) J Lipid Res , vol.23 , pp. 97-104
    • Krauss, R.M.1    Burke, D.J.2
  • 7
    • 0022521147 scopus 로고
    • Genetic control of low-density lipoprotein subclasses
    • Austin MA, Krauss RM. Genetic control of low-density lipoprotein subclasses. Lancet. 1986;2:592-5.
    • (1986) Lancet , vol.2 , pp. 592-595
    • Austin, M.A.1    Krauss, R.M.2
  • 8
    • 0025118667 scopus 로고
    • Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk
    • Austin MA, King MC, Vranizan KM, Krauss RM. Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk. Circulation. 1990;82:495-506.
    • (1990) Circulation , vol.82 , pp. 495-506
    • Austin, M.A.1    King, M.C.2    Vranizan, K.M.3    Krauss, R.M.4
  • 9
    • 0027183606 scopus 로고
    • Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles
    • Reaven GM, Chen YD, Jeppesen J, Maheux P, Krauss RM. Insulin resistance and hyperinsulinemia in individuals with small, dense low density lipoprotein particles. J Clin Invest. 1993;92:141-6.
    • (1993) J Clin Invest , vol.92 , pp. 141-146
    • Reaven, G.M.1    Chen, Y.D.2    Jeppesen, J.3    Maheux, P.4    Krauss, R.M.5
  • 10
    • 0034746490 scopus 로고    scopus 로고
    • Proatherogenic role of elevated CE transfer from HDL to VLDL (1) and dense LDL in type 2 diabetes: Impact of the degree of triglyceridemia
    • Guerin M, Le Goff W, Lassel TS, Van Tol A, Steiner G, Chapman MJ. Proatherogenic role of elevated CE transfer from HDL to VLDL (1) and dense LDL in type 2 diabetes: impact of the degree of triglyceridemia. Arterioscler Thromb Vasc Biol. 2001;21:282-8.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 282-288
    • Guerin, M.1    Le Goff, W.2    Lassel, T.S.3    Van Tol, A.4    Steiner, G.5    Chapman, M.J.6
  • 12
    • 33749500141 scopus 로고    scopus 로고
    • A combination therapy including psyllium and plant sterols lowers LDL cholesterol by modifying lipoprotein metabolism in hypercholesterolemic individuals
    • Shrestha S, Volek JS, Udani J, Wood RJ, Green CM, Aggarwal D, Contois JH, Kavoussi B, Fernandez ML. A combination therapy including psyllium and plant sterols lowers LDL cholesterol by modifying lipoprotein metabolism in hypercholesterolemic individuals. J Nutr. 2006;136:2492-7.
    • (2006) J Nutr , vol.136 , pp. 2492-2497
    • Shrestha, S.1    Volek, J.S.2    Udani, J.3    Wood, R.J.4    Green, C.M.5    Aggarwal, D.6    Contois, J.H.7    Kavoussi, B.8    Fernandez, M.L.9
  • 14
    • 0033999703 scopus 로고    scopus 로고
    • Gender and hormonal status affect the hypolipidemic mechanisms of dietary soluble fiber in guinea pigs
    • Roy S, Vega-Lopez S, Fernandez ML. Gender and hormonal status affect the hypolipidemic mechanisms of dietary soluble fiber in guinea pigs. J Nutr. 2000;130:600-7.
    • (2000) J Nutr , vol.130 , pp. 600-607
    • Roy, S.1    Vega-Lopez, S.2    Fernandez, M.L.3
  • 15
    • 0034833820 scopus 로고    scopus 로고
    • Sex and hormonal status influence plasma lipid responses to psyllium
    • Vega-Lopez S, Vidal-Quintanar RL, Fernandez ML. Sex and hormonal status influence plasma lipid responses to psyllium. Am J Clin Nutr. 2001;74:435-41.
    • (2001) Am J Clin Nutr , vol.74 , pp. 435-441
    • Vega-Lopez, S.1    Vidal-Quintanar, R.L.2    Fernandez, M.L.3
  • 16
    • 0030572768 scopus 로고    scopus 로고
    • Investigation of low density lipoprotein subfractions as a coronary risk factor in normotriglyceridaemic men
    • Rajman I, Kendall MJ, Cramb R, Holder RL, Salih M, Gammage MD. Investigation of low density lipoprotein subfractions as a coronary risk factor in normotriglyceridaemic men. Atherosclerosis. 1996;125:231-42.
    • (1996) Atherosclerosis , vol.125 , pp. 231-242
    • Rajman, I.1    Kendall, M.J.2    Cramb, R.3    Holder, R.L.4    Salih, M.5    Gammage, M.D.6
  • 17
    • 0027411170 scopus 로고
    • Oxidation of low-density lipoproteins: Intraindividual variability and the effect of dietary linoleate supplementation
    • Abbey M, Belling GB, Noakes M, Hirata F, Nestel PJ. Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation. Am J Clin Nutr. 1993;57:391-8.
    • (1993) Am J Clin Nutr , vol.57 , pp. 391-398
    • Abbey, M.1    Belling, G.B.2    Noakes, M.3    Hirata, F.4    Nestel, P.J.5
  • 18
    • 0018178434 scopus 로고
    • A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
    • Markwell MA, Haas SM, Bieber LL, Tolbert NE. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem. 1978;87:206-10.
    • (1978) Anal Biochem , vol.87 , pp. 206-210
    • Markwell, M.A.1    Haas, S.M.2    Bieber, L.L.3    Tolbert, N.E.4
  • 19
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
    • Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl. 1968;97:77-89.
    • (1968) Scand J Clin Lab Invest Suppl , vol.97 , pp. 77-89
    • Boyum, A.1
  • 20
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-9.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 21
    • 21244499405 scopus 로고    scopus 로고
    • GAPDH as a housekeeping gene: Analysis of GAPDH mRNA expression in a panel of 72 human tissues
    • Barber RD, Harmer DW, Coleman RA, Clark BJ. GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues. Physiol Genomics. 2005;21:389-95.
    • (2005) Physiol Genomics , vol.21 , pp. 389-395
    • Barber, R.D.1    Harmer, D.W.2    Coleman, R.A.3    Clark, B.J.4
  • 23
    • 0029740950 scopus 로고    scopus 로고
    • Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women
    • Gardner C, Fortman S, Krauss R. Association of small low-density lipoprotein particles with the incidence of coronary artery disease in men and women. JAMA. 1996;276:875-81.
    • (1996) JAMA , vol.276 , pp. 875-881
    • Gardner, C.1    Fortman, S.2    Krauss, R.3
  • 24
    • 16544387987 scopus 로고    scopus 로고
    • Diets containing barley significantly reduce lipids in mildly hypercholesterolemic men and women
    • Behall KM, Cholfield DJ, Hallfrisch J. Diets containing barley significantly reduce lipids in mildly hypercholesterolemic men and women. Am J Clin Nutr. 2004;80:1185-93.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1185-1193
    • Behall, K.M.1    Cholfield, D.J.2    Hallfrisch, J.3
  • 25
    • 0036076367 scopus 로고    scopus 로고
    • High-fiber oat cereal compared with wheat cereal consumption favorably alters LDL-cholesterol subclass and particle numbers in middle-aged and older men
    • Davy BM, Davy KP, Ho RC, Beske SD, Davrath LR, Melby CL. High-fiber oat cereal compared with wheat cereal consumption favorably alters LDL-cholesterol subclass and particle numbers in middle-aged and older men. Am J Clin Nutr. 2002;76:351-8.
    • (2002) Am J Clin Nutr , vol.76 , pp. 351-358
    • Davy, B.M.1    Davy, K.P.2    Ho, R.C.3    Beske, S.D.4    Davrath, L.R.5    Melby, C.L.6
  • 26
    • 1542376913 scopus 로고    scopus 로고
    • Unesterified plant sterols and stanols do not effect LDL electrophoretic characteristics in hypercholesterolemic subjects
    • Charest A, Desroches S, Vanstone CA, Jones PJH, Lamarche B. Unesterified plant sterols and stanols do not effect LDL electrophoretic characteristics in hypercholesterolemic subjects. J Nutr. 2004;134:592-5.
    • (2004) J Nutr , vol.134 , pp. 592-595
    • Charest, A.1    Desroches, S.2    Vanstone, C.A.3    Jones, P.J.H.4    Lamarche, B.5
  • 28
    • 1542286864 scopus 로고    scopus 로고
    • Soy protein favorably affects LDL size independently of isoflavones in hypercholesterolemic men and women
    • Desroches S, Mauger JF, Ausman LM, Lichtenstein AH, Lamarche B. Soy protein favorably affects LDL size independently of isoflavones in hypercholesterolemic men and women. J Nutr. 2004;134:574-9.
    • (2004) J Nutr , vol.134 , pp. 574-579
    • Desroches, S.1    Mauger, J.F.2    Ausman, L.M.3    Lichtenstein, A.H.4    Lamarche, B.5
  • 29
    • 0034520192 scopus 로고    scopus 로고
    • An olive oil-rich diet results in higher concentrations of LDL cholesterol and a higher number of LDL subfraction particles than rapeseed oil and sunflower oil diets
    • Pedersen A, Baumstark MW, Marckmann P, Gylling H, Sandstrom B. An olive oil-rich diet results in higher concentrations of LDL cholesterol and a higher number of LDL subfraction particles than rapeseed oil and sunflower oil diets. J Lipid Res. 2000;41:1901-11.
    • (2000) J Lipid Res , vol.41 , pp. 1901-1911
    • Pedersen, A.1    Baumstark, M.W.2    Marckmann, P.3    Gylling, H.4    Sandstrom, B.5
  • 30
    • 17244367975 scopus 로고    scopus 로고
    • Effect of plant sterols and endurance training on LDL particle size and distribution in previously sedentary hypercholesterolemic adults
    • Varady KA, St-Pierre AC, Lamarche B, Jones PJ. Effect of plant sterols and endurance training on LDL particle size and distribution in previously sedentary hypercholesterolemic adults. Eur J Clin Nutr. 2005;59:518-25.
    • (2005) Eur J Clin Nutr , vol.59 , pp. 518-525
    • Varady, K.A.1    St-Pierre, A.C.2    Lamarche, B.3    Jones, P.J.4
  • 32
    • 0035150503 scopus 로고    scopus 로고
    • Atherogenic lipoprotein phenotype and diet-gene interactions
    • Krauss RM. Atherogenic lipoprotein phenotype and diet-gene interactions. J Nutr. 2001;131:S340-3.
    • (2001) J Nutr , vol.131
    • Krauss, R.M.1
  • 33
    • 34247897543 scopus 로고    scopus 로고
    • Small, dense low-density-lipoproteins and the metabolic syndrome
    • Rizzo M, Berneis K. Small, dense low-density-lipoproteins and the metabolic syndrome. Diabetes Metab Res Rev. 2007;156:361-7.
    • (2007) Diabetes Metab Res Rev , vol.156 , pp. 361-367
    • Rizzo, M.1    Berneis, K.2
  • 34
    • 0344739627 scopus 로고    scopus 로고
    • Role of lipases, lecithin:cholesterol acyltransferase and cholesteryl ester transfer protein in abnormal high density lipoprotein metabolism in insulin resistance and type 2 diabetes mellitus
    • de Vries R, Borggreve SE, Dullaart RP. Role of lipases, lecithin:cholesterol acyltransferase and cholesteryl ester transfer protein in abnormal high density lipoprotein metabolism in insulin resistance and type 2 diabetes mellitus. Clin Lab. 2003;49:601-13.
    • (2003) Clin Lab , vol.49 , pp. 601-613
    • de Vries, R.1    Borggreve, S.E.2    Dullaart, R.P.3
  • 35
    • 0032812981 scopus 로고    scopus 로고
    • Remodelling of high density lipoproteins by plasma factors
    • Rye KA, Clay MA, Barter PJ. Remodelling of high density lipoproteins by plasma factors. Atherosclerosis. 1999;145:227-38.
    • (1999) Atherosclerosis , vol.145 , pp. 227-238
    • Rye, K.A.1    Clay, M.A.2    Barter, P.J.3
  • 36
    • 0031051365 scopus 로고    scopus 로고
    • Regulation of apolipoprotein B-containing lipoproteins by dietary soluble fiber in guinea pigs
    • Fernandez ML, Vergara-Jimenez M, Conde AK, Behr T, Abdel-Fattah G. Regulation of apolipoprotein B-containing lipoproteins by dietary soluble fiber in guinea pigs. Am J Clin Nutr. 1997;65:814-22.
    • (1997) Am J Clin Nutr , vol.65 , pp. 814-822
    • Fernandez, M.L.1    Vergara-Jimenez, M.2    Conde, A.K.3    Behr, T.4    Abdel-Fattah, G.5
  • 37
    • 0031794025 scopus 로고    scopus 로고
    • Dietary pectin with high viscosity lowers plasma and liver cholesterol concentration and plasma cholesteryl ester transfer protein activity in hamsters
    • Terpstra AHM, Lapre JA, de Vines H, Beynen AC. Dietary pectin with high viscosity lowers plasma and liver cholesterol concentration and plasma cholesteryl ester transfer protein activity in hamsters. J Nutr. 1998;128:1944-9.
    • (1998) J Nutr , vol.128 , pp. 1944-1949
    • Terpstra, A.H.M.1    Lapre, J.A.2    de Vines, H.3    Beynen, A.C.4
  • 38
    • 0037381181 scopus 로고    scopus 로고
    • Homma Y, Ikeda I, Ishikawa T, Tateno M, Sugano M, Nakamura H. Decrease in plasma low-density lipoprotein cholesterol, apolipoprotein B, cholesteryl ester transfer protein, and oxidized low-density lipoprotein by plant stanol ester-containing spread: a randomized, placebo-controlled trial. Nutrition. 2003;19:369-74.
    • Homma Y, Ikeda I, Ishikawa T, Tateno M, Sugano M, Nakamura H. Decrease in plasma low-density lipoprotein cholesterol, apolipoprotein B, cholesteryl ester transfer protein, and oxidized low-density lipoprotein by plant stanol ester-containing spread: a randomized, placebo-controlled trial. Nutrition. 2003;19:369-74.
  • 39
    • 5644257080 scopus 로고    scopus 로고
    • Effects of a new low dose soy protein/beta-sitosterol association on plasma lipid levels and oxidation
    • Cicero AF, Minardi M, Mirembe S, Pedro E, Gaddi A. Effects of a new low dose soy protein/beta-sitosterol association on plasma lipid levels and oxidation. Eur J Nutr. 2004;43:319-22.
    • (2004) Eur J Nutr , vol.43 , pp. 319-322
    • Cicero, A.F.1    Minardi, M.2    Mirembe, S.3    Pedro, E.4    Gaddi, A.5
  • 40
    • 0032969540 scopus 로고    scopus 로고
    • Pectin and psyllium decrease the susceptibility of LDL to oxidation in guinea pigs
    • Vergara-Jimenez M, Furr H, Fernandez ML. Pectin and psyllium decrease the susceptibility of LDL to oxidation in guinea pigs. J Nutr Biochem. 1999;10:118-24.
    • (1999) J Nutr Biochem , vol.10 , pp. 118-124
    • Vergara-Jimenez, M.1    Furr, H.2    Fernandez, M.L.3
  • 41
    • 0028212483 scopus 로고
    • Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver
    • Powell EE, Kroon PA. Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver. J Clin Invest. 1994;93:2168-74.
    • (1994) J Clin Invest , vol.93 , pp. 2168-2174
    • Powell, E.E.1    Kroon, P.A.2
  • 42
    • 33748705126 scopus 로고    scopus 로고
    • Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism
    • Aggarwal D, Freake HC, Soliman GA, Dutta A, Fernandez ML. Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism. Lipids Health Dis. 2006;5:22.
    • (2006) Lipids Health Dis , vol.5 , pp. 22
    • Aggarwal, D.1    Freake, H.C.2    Soliman, G.A.3    Dutta, A.4    Fernandez, M.L.5
  • 44
    • 0028894857 scopus 로고
    • Distinct mechanisms of plasma LDL lowering by dietary fiber in the guinea pig: Specific effects of pectin, guar gum, and psyllium
    • Fernandez ML. Distinct mechanisms of plasma LDL lowering by dietary fiber in the guinea pig: specific effects of pectin, guar gum, and psyllium. J Lipid Res. 1995;36:2394-404.
    • (1995) J Lipid Res , vol.36 , pp. 2394-2404
    • Fernandez, M.L.1
  • 45
    • 0032929285 scopus 로고    scopus 로고
    • Increased fecal bile acid excretion and changes in the circulating bile acid pool are involved in the hypocholesterolemic and gallstone-preventive actions of psyllium in hamsters
    • Trautwein EA, Kunath-Rau A, Erbersdobler HF. Increased fecal bile acid excretion and changes in the circulating bile acid pool are involved in the hypocholesterolemic and gallstone-preventive actions of psyllium in hamsters. J Nutr. 1999;129:896-902.
    • (1999) J Nutr , vol.129 , pp. 896-902
    • Trautwein, E.A.1    Kunath-Rau, A.2    Erbersdobler, H.F.3
  • 46
    • 0036482333 scopus 로고    scopus 로고
    • Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women
    • Plat J, Mensink RP. Effects of plant stanol esters on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase mRNA expression in mononuclear blood cells of healthy men and women. FASEB J. 2001;16:258-60.
    • (2001) FASEB J , vol.16 , pp. 258-260
    • Plat, J.1    Mensink, R.P.2
  • 47
    • 0037229119 scopus 로고    scopus 로고
    • Sex and hormonal status modulate the effects of psyllium on plasma lipids and monocyte gene expression in humans
    • Vega-Lopez S, Freake HC, Fernandez ML. Sex and hormonal status modulate the effects of psyllium on plasma lipids and monocyte gene expression in humans. J Nutr. 2003;133:67-70.
    • (2003) J Nutr , vol.133 , pp. 67-70
    • Vega-Lopez, S.1    Freake, H.C.2    Fernandez, M.L.3


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