메뉴 건너뛰기




Volumn 18, Issue 1, 2009, Pages 157-174

Surgical Management of von Hippel-Lindau Disease: Urologic Considerations

Author keywords

Carcinoma; Hereditary diseases; Kidney cysts; Nephrectomy; Pheochromocytoma; Renal cell; von Hippel Lindau disease

Indexed keywords

CULLIN; ELONGIN B; ELONGIN C; ENDOTHELIAL CELL GROWTH FACTOR; ERYTHROPOIETIN; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; UBIQUITIN; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN;

EID: 56849124658     PISSN: 10553207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.soc.2008.08.005     Document Type: Review
Times cited : (10)

References (115)
  • 1
    • 34347163881 scopus 로고
    • Uber eine sehf self seltene erkrankung der netzhaut
    • von Hippel E. Uber eine sehf self seltene erkrankung der netzhaut. Klinische Beobachtungen Arch Opthalmol 59 (1904) 83-106
    • (1904) Klinische Beobachtungen Arch Opthalmol , vol.59 , pp. 83-106
    • von Hippel, E.1
  • 2
    • 34347158133 scopus 로고
    • Die anatomische Grund lage der von mir beschriebenen 'sehr seltenen Erkrankung der Netzhaut'
    • Von Hippel E. Die anatomische Grund lage der von mir beschriebenen 'sehr seltenen Erkrankung der Netzhaut'. Graefes Arch Ophthalmol 79 (1911) 350-377
    • (1911) Graefes Arch Ophthalmol , vol.79 , pp. 350-377
    • Von Hippel, E.1
  • 3
    • 0002058311 scopus 로고
    • Studien ber kleinbirncysten bau: pathogenese und beziehungen zur angiomatosis retinae
    • Lindau A. Studien ber kleinbirncysten bau: pathogenese und beziehungen zur angiomatosis retinae. Acta radiol Microbiol Scandinavica 1 Suppl (1926) 1-128
    • (1926) Acta radiol Microbiol Scandinavica , vol.1 , Issue.SUPPL , pp. 1-128
    • Lindau, A.1
  • 4
    • 50549195332 scopus 로고
    • Lindau's disease. Review of the literature and study of a large kindred
    • Melmon K.L., and Rosen S.W. Lindau's disease. Review of the literature and study of a large kindred. Am J Med 36 (1964) 595-617
    • (1964) Am J Med , vol.36 , pp. 595-617
    • Melmon, K.L.1    Rosen, S.W.2
  • 5
    • 0025000210 scopus 로고
    • Clinical features and natural history of von Hippel-Lindau disease
    • Maher E.R., Yates J.R., Harries R., et al. Clinical features and natural history of von Hippel-Lindau disease. Q J Med 77 283 (1990) 1151-1163
    • (1990) Q J Med , vol.77 , Issue.283 , pp. 1151-1163
    • Maher, E.R.1    Yates, J.R.2    Harries, R.3
  • 6
    • 0037709883 scopus 로고    scopus 로고
    • von Hippel-Lindau disease
    • Lonser R.R., Glenn G.M., Walther M., et al. von Hippel-Lindau disease. Lancet 361 9374 (2003) 2059-2067
    • (2003) Lancet , vol.361 , Issue.9374 , pp. 2059-2067
    • Lonser, R.R.1    Glenn, G.M.2    Walther, M.3
  • 8
    • 0023630505 scopus 로고
    • Basic criteria for clinical diagnosis and genetic counselling in von Hippel-Lindau syndrome
    • Neumann H.P. Basic criteria for clinical diagnosis and genetic counselling in von Hippel-Lindau syndrome. Vasa 16 3 (1987) 220-226
    • (1987) Vasa , vol.16 , Issue.3 , pp. 220-226
    • Neumann, H.P.1
  • 9
    • 0032863385 scopus 로고    scopus 로고
    • Renal cancer in families with hereditary renal cancer: prospective analysis of a tumor size threshold for renal parenchymal sparing surgery
    • Walther M.M., Choyke P.L., Glenn G., et al. Renal cancer in families with hereditary renal cancer: prospective analysis of a tumor size threshold for renal parenchymal sparing surgery. J Urol 161 5 (1999) 1475-1479
    • (1999) J Urol , vol.161 , Issue.5 , pp. 1475-1479
    • Walther, M.M.1    Choyke, P.L.2    Glenn, G.3
  • 10
    • 0028139322 scopus 로고
    • Conservative surgical therapy of localized renal cell carcinoma in von Hippel-Lindau disease
    • Lund G.O., Fallon B., Curtis M.A., et al. Conservative surgical therapy of localized renal cell carcinoma in von Hippel-Lindau disease. Cancer 74 9 (1994) 2541-2545
    • (1994) Cancer , vol.74 , Issue.9 , pp. 2541-2545
    • Lund, G.O.1    Fallon, B.2    Curtis, M.A.3
  • 11
    • 0035131313 scopus 로고    scopus 로고
    • Parenchymal sparing surgery in patients with hereditary renal cell carcinoma: 10-year experience
    • Herring J.C., Enquist E.G., Chernoff A., et al. Parenchymal sparing surgery in patients with hereditary renal cell carcinoma: 10-year experience. J Urol 165 3 (2001) 777-781
    • (2001) J Urol , vol.165 , Issue.3 , pp. 777-781
    • Herring, J.C.1    Enquist, E.G.2    Chernoff, A.3
  • 12
    • 0024451493 scopus 로고
    • Cytogenetic abnormalities in tumors of patients with von Hippel-Lindau disease
    • Jordan D.K., Patil S.R., Divelbiss J.E., et al. Cytogenetic abnormalities in tumors of patients with von Hippel-Lindau disease. Cancer Genet Cytogenet 42 2 (1989) 227-241
    • (1989) Cancer Genet Cytogenet , vol.42 , Issue.2 , pp. 227-241
    • Jordan, D.K.1    Patil, S.R.2    Divelbiss, J.E.3
  • 13
    • 0028887421 scopus 로고
    • Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer
    • Linehan W.M., Lerman M.I., and Zbar B. Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer. JAMA 273 7 (1995) 564-570
    • (1995) JAMA , vol.273 , Issue.7 , pp. 564-570
    • Linehan, W.M.1    Lerman, M.I.2    Zbar, B.3
  • 14
    • 0028924005 scopus 로고
    • Characterization of the renal pathology of a familial form of renal cell carcinoma associated with von Hippel-Lindau disease: clinical and molecular genetic implications
    • Poston C.D., Jaffe G.S., Lubensky I.A., et al. Characterization of the renal pathology of a familial form of renal cell carcinoma associated with von Hippel-Lindau disease: clinical and molecular genetic implications. J Urol 153 1 (1995) 22-26
    • (1995) J Urol , vol.153 , Issue.1 , pp. 22-26
    • Poston, C.D.1    Jaffe, G.S.2    Lubensky, I.A.3
  • 15
    • 56849118760 scopus 로고    scopus 로고
    • Wein A.J., Kavoussi L.R., Novick A.C., et al. (Eds), Saunders Elsevier, Philadelphia
    • In: Wein A.J., Kavoussi L.R., Novick A.C., et al. (Eds). Campbell-Walsh urology. 9th edition (2007), Saunders Elsevier, Philadelphia 3306
    • (2007) Campbell-Walsh urology. 9th edition , pp. 3306
  • 16
    • 0023802735 scopus 로고
    • Renal pathology in von Hippel-Lindau disease
    • Solomon D., and Schwartz A. Renal pathology in von Hippel-Lindau disease. Hum Pathol 19 9 (1988) 1072-1079
    • (1988) Hum Pathol , vol.19 , Issue.9 , pp. 1072-1079
    • Solomon, D.1    Schwartz, A.2
  • 17
    • 0026689665 scopus 로고
    • Long-term followup after nephron sparing surgery for renal cell carcinoma in von Hippel-Lindau disease
    • Novick A.C., and Streem S.B. Long-term followup after nephron sparing surgery for renal cell carcinoma in von Hippel-Lindau disease. J Urol 147 6 (1992) 1488-1490
    • (1992) J Urol , vol.147 , Issue.6 , pp. 1488-1490
    • Novick, A.C.1    Streem, S.B.2
  • 18
    • 0027477688 scopus 로고
    • Conservative renal surgery for renal cell carcinoma in von Hippel-Lindau's disease
    • Frydenberg M., Malek R.S., and Zincke H. Conservative renal surgery for renal cell carcinoma in von Hippel-Lindau's disease. J Urol 149 3 (1993) 461-464
    • (1993) J Urol , vol.149 , Issue.3 , pp. 461-464
    • Frydenberg, M.1    Malek, R.S.2    Zincke, H.3
  • 19
    • 0026495630 scopus 로고
    • The natural history of renal lesions in von Hippel-Lindau disease: a serial CT study in 28 patients
    • Choyke P.L., Glenn G.M., Walther M.M., et al. The natural history of renal lesions in von Hippel-Lindau disease: a serial CT study in 28 patients. AJR Am J Roentgenol 159 6 (1992) 1229-1234
    • (1992) AJR Am J Roentgenol , vol.159 , Issue.6 , pp. 1229-1234
    • Choyke, P.L.1    Glenn, G.M.2    Walther, M.M.3
  • 20
    • 0028908978 scopus 로고
    • Parenchymal sparing surgery in patients with hereditary renal cell carcinoma
    • Walther M.M., Choyke P.L., Weiss G., et al. Parenchymal sparing surgery in patients with hereditary renal cell carcinoma. J Urol 153 3 Pt 2 (1995) 913-916
    • (1995) J Urol , vol.153 , Issue.3 PART 2 , pp. 913-916
    • Walther, M.M.1    Choyke, P.L.2    Weiss, G.3
  • 21
    • 0024493153 scopus 로고
    • von Hippel-Lindau disease affecting 43 members of a single kindred
    • Lamiell J.M., Salazar F.G., and Hsia Y.E. von Hippel-Lindau disease affecting 43 members of a single kindred. Medicine (Baltimore) 68 1 (1989) 1-29
    • (1989) Medicine (Baltimore) , vol.68 , Issue.1 , pp. 1-29
    • Lamiell, J.M.1    Salazar, F.G.2    Hsia, Y.E.3
  • 22
    • 0029744920 scopus 로고    scopus 로고
    • Renal involvement in von Hippel-Lindau disease
    • Chauveau D., Duvic C., Chretien Y., et al. Renal involvement in von Hippel-Lindau disease. Kidney Int 50 3 (1996) 944-951
    • (1996) Kidney Int , vol.50 , Issue.3 , pp. 944-951
    • Chauveau, D.1    Duvic, C.2    Chretien, Y.3
  • 23
    • 0031809312 scopus 로고    scopus 로고
    • Nephron-sparing surgery and renal transplantation in patients with renal cell carcinoma and von Hippel-Lindau disease
    • Goldfarb D.A. Nephron-sparing surgery and renal transplantation in patients with renal cell carcinoma and von Hippel-Lindau disease. J Intern Med 243 6 (1998) 563-567
    • (1998) J Intern Med , vol.243 , Issue.6 , pp. 563-567
    • Goldfarb, D.A.1
  • 24
    • 0028938702 scopus 로고
    • von Hippel-Lindau disease: genetic, clinical, and imaging features
    • Choyke P.L., Glenn G.M., Walther M.M., et al. von Hippel-Lindau disease: genetic, clinical, and imaging features. Radiology 194 3 (1995) 629-642
    • (1995) Radiology , vol.194 , Issue.3 , pp. 629-642
    • Choyke, P.L.1    Glenn, G.M.2    Walther, M.M.3
  • 25
    • 0018665933 scopus 로고
    • The radiographic manifestations of von Hippel-Lindau disease
    • Fill W.L., Lamiell J.M., and Polk N.O. The radiographic manifestations of von Hippel-Lindau disease. Radiology 133 2 (1979) 289-295
    • (1979) Radiology , vol.133 , Issue.2 , pp. 289-295
    • Fill, W.L.1    Lamiell, J.M.2    Polk, N.O.3
  • 26
    • 0025273491 scopus 로고
    • von Hippel-Lindau disease: radiologic screening for visceral manifestations
    • Choyke P.L., Filling-Katz M.R., Shawker T.H., et al. von Hippel-Lindau disease: radiologic screening for visceral manifestations. Radiology 174 3 Pt 1 (1990) 815-820
    • (1990) Radiology , vol.174 , Issue.3 PART 1 , pp. 815-820
    • Choyke, P.L.1    Filling-Katz, M.R.2    Shawker, T.H.3
  • 27
    • 0033631179 scopus 로고    scopus 로고
    • Somatic mosaicism in von Hippel-Lindau disease
    • Murgia A., Martella M., Vinanzi C., et al. Somatic mosaicism in von Hippel-Lindau disease. Hum Mutat 15 1 (2000) 114
    • (2000) Hum Mutat , vol.15 , Issue.1 , pp. 114
    • Murgia, A.1    Martella, M.2    Vinanzi, C.3
  • 28
    • 0033909888 scopus 로고    scopus 로고
    • Mosaicism in von Hippel-Lindau disease: lessons from kindreds with germline mutations identified in offspring with mosaic parents
    • Sgambati M.T., Stolle C., Choyke P.L., et al. Mosaicism in von Hippel-Lindau disease: lessons from kindreds with germline mutations identified in offspring with mosaic parents. Am J Hum Genet 66 1 (2000) 84-91
    • (2000) Am J Hum Genet , vol.66 , Issue.1 , pp. 84-91
    • Sgambati, M.T.1    Stolle, C.2    Choyke, P.L.3
  • 29
    • 16144365122 scopus 로고    scopus 로고
    • Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan
    • Zbar B., Kishida T., Chen F., et al. Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan. Hum Mutat 8 4 (1996) 348-357
    • (1996) Hum Mutat , vol.8 , Issue.4 , pp. 348-357
    • Zbar, B.1    Kishida, T.2    Chen, F.3
  • 30
    • 0031042949 scopus 로고    scopus 로고
    • Renal cysts, renal cancer and von Hippel-Lindau disease
    • Neumann H.P., and Zbar B. Renal cysts, renal cancer and von Hippel-Lindau disease. Kidney Int 51 1 (1997) 16-26
    • (1997) Kidney Int , vol.51 , Issue.1 , pp. 16-26
    • Neumann, H.P.1    Zbar, B.2
  • 31
    • 0025736587 scopus 로고
    • Overview: genes that predispose to cancer
    • Knudson Jr. A.G. Overview: genes that predispose to cancer. Mutat Res 247 2 (1991) 185-190
    • (1991) Mutat Res , vol.247 , Issue.2 , pp. 185-190
    • Knudson Jr., A.G.1
  • 32
    • 0027400599 scopus 로고
    • Introduction to the genetics of primary renal tumors in children
    • Knudson Jr. A.G. Introduction to the genetics of primary renal tumors in children. Med Pediatr Oncol 21 3 (1993) 193-198
    • (1993) Med Pediatr Oncol , vol.21 , Issue.3 , pp. 193-198
    • Knudson Jr., A.G.1
  • 33
    • 0027240519 scopus 로고
    • Identification of the von Hippel-Lindau disease tumor suppressor gene
    • Latif F., Tory K., Gnarra J., et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260 5112 (1993) 1317-1320
    • (1993) Science , vol.260 , Issue.5112 , pp. 1317-1320
    • Latif, F.1    Tory, K.2    Gnarra, J.3
  • 34
    • 0029847090 scopus 로고    scopus 로고
    • Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients
    • Lubensky I.A., Gnarra J.R., Bertheau P., et al. Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients. Am J Pathol 149 6 (1996) 2089-2094
    • (1996) Am J Pathol , vol.149 , Issue.6 , pp. 2089-2094
    • Lubensky, I.A.1    Gnarra, J.R.2    Bertheau, P.3
  • 35
    • 0038654360 scopus 로고    scopus 로고
    • Studying cancer families to identify kidney cancer genes
    • Zbar B., Klausner R., and Linehan W.M. Studying cancer families to identify kidney cancer genes. Annu Rev Med 54 (2003) 217-233
    • (2003) Annu Rev Med , vol.54 , pp. 217-233
    • Zbar, B.1    Klausner, R.2    Linehan, W.M.3
  • 36
    • 34548075520 scopus 로고    scopus 로고
    • Pseudohypoxic pathways in renal cell carcinoma
    • Bratslavsky G., Sudarshan S., Neckers L., et al. Pseudohypoxic pathways in renal cell carcinoma. Clin Cancer Res 13 16 (2007) 4667-4671
    • (2007) Clin Cancer Res , vol.13 , Issue.16 , pp. 4667-4671
    • Bratslavsky, G.1    Sudarshan, S.2    Neckers, L.3
  • 37
    • 25644454404 scopus 로고    scopus 로고
    • Pharmaceuticals: a new grammar for drug discovery
    • Fishman M.C., and Porter J.A. Pharmaceuticals: a new grammar for drug discovery. Nature 437 7058 (2005) 491-493
    • (2005) Nature , vol.437 , Issue.7058 , pp. 491-493
    • Fishman, M.C.1    Porter, J.A.2
  • 38
    • 0018736628 scopus 로고
    • Hereditary renal-cell carcinoma associated with a chromosomal translocation
    • Cohen A.J., Li F.P., Berg S., et al. Hereditary renal-cell carcinoma associated with a chromosomal translocation. N Engl J Med 301 11 (1979) 592-595
    • (1979) N Engl J Med , vol.301 , Issue.11 , pp. 592-595
    • Cohen, A.J.1    Li, F.P.2    Berg, S.3
  • 39
    • 0019998262 scopus 로고
    • Familial renal cell carcinoma with a 3;11 chromosome translocation limited to tumor cells
    • Pathak S., Strong L.C., Ferrell R.E., et al. Familial renal cell carcinoma with a 3;11 chromosome translocation limited to tumor cells. Science 217 4563 (1982) 939-941
    • (1982) Science , vol.217 , Issue.4563 , pp. 939-941
    • Pathak, S.1    Strong, L.C.2    Ferrell, R.E.3
  • 40
    • 0023181644 scopus 로고
    • Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma
    • Zbar B., Brauch H., Talmadge C., et al. Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma. Nature 327 6124 (1987) 721-724
    • (1987) Nature , vol.327 , Issue.6124 , pp. 721-724
    • Zbar, B.1    Brauch, H.2    Talmadge, C.3
  • 41
    • 0025857484 scopus 로고
    • Molecular analysis of genetic changes in the origin and development of renal cell carcinoma
    • Anglard P., Tory K., Brauch H., et al. Molecular analysis of genetic changes in the origin and development of renal cell carcinoma. Cancer Res 51 4 (1991) 1071-1077
    • (1991) Cancer Res , vol.51 , Issue.4 , pp. 1071-1077
    • Anglard, P.1    Tory, K.2    Brauch, H.3
  • 42
    • 0027461398 scopus 로고
    • von Hippel-Lindau syndrome: cloning and identification of the plasma membrane Ca(++)-transporting ATPase isoform 2 gene that resides in the von Hippel-Lindau gene region
    • Latif F., Duh F.M., Gnarra J., et al. von Hippel-Lindau syndrome: cloning and identification of the plasma membrane Ca(++)-transporting ATPase isoform 2 gene that resides in the von Hippel-Lindau gene region. Cancer Res 53 4 (1993) 861-867
    • (1993) Cancer Res , vol.53 , Issue.4 , pp. 861-867
    • Latif, F.1    Duh, F.M.2    Gnarra, J.3
  • 43
    • 7844234770 scopus 로고    scopus 로고
    • Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene
    • Stolle C., Glenn G., Zbar B., et al. Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene. Hum Mutat 12 6 (1998) 417-423
    • (1998) Hum Mutat , vol.12 , Issue.6 , pp. 417-423
    • Stolle, C.1    Glenn, G.2    Zbar, B.3
  • 44
    • 0028072991 scopus 로고
    • Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
    • Herman J.G., Latif F., Weng Y., et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A 91 21 (1994) 9700-9704
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.21 , pp. 9700-9704
    • Herman, J.G.1    Latif, F.2    Weng, Y.3
  • 45
    • 0029843950 scopus 로고    scopus 로고
    • Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
    • Herman J.G., Graff J.R., Myohanen S., et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 93 18 (1996) 9821-9826
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.18 , pp. 9821-9826
    • Herman, J.G.1    Graff, J.R.2    Myohanen, S.3
  • 46
    • 0031776704 scopus 로고    scopus 로고
    • Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis
    • Clifford S.C., Prowse A.H., Affara N.A., et al. Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis. Genes Chromosomes Cancer 22 3 (1998) 200-209
    • (1998) Genes Chromosomes Cancer , vol.22 , Issue.3 , pp. 200-209
    • Clifford, S.C.1    Prowse, A.H.2    Affara, N.A.3
  • 47
    • 0029090338 scopus 로고
    • Tumour suppression by the human von Hippel-Lindau gene product
    • Iliopoulos O., Kibel A., Gray S., et al. Tumour suppression by the human von Hippel-Lindau gene product. Nat Med 1 8 (1995) 822-826
    • (1995) Nat Med , vol.1 , Issue.8 , pp. 822-826
    • Iliopoulos, O.1    Kibel, A.2    Gray, S.3
  • 48
    • 33846876103 scopus 로고    scopus 로고
    • Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics
    • Linehan W.M., Pinto P.A., Srinivasan R., et al. Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics. Clin Cancer Res 13 2 Pt 2 (2007) 671s-679s
    • (2007) Clin Cancer Res , vol.13 , Issue.2 PART 2
    • Linehan, W.M.1    Pinto, P.A.2    Srinivasan, R.3
  • 49
    • 0027954044 scopus 로고
    • Mutations of the VHL tumour suppressor gene in renal carcinoma
    • Gnarra J.R., Tory K., Weng Y., et al. Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet 7 1 (1994) 85-90
    • (1994) Nat Genet , vol.7 , Issue.1 , pp. 85-90
    • Gnarra, J.R.1    Tory, K.2    Weng, Y.3
  • 50
    • 0028235907 scopus 로고
    • Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas
    • Shuin T., Kondo K., Torigoe S., et al. Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas. Cancer Res 54 11 (1994) 2852-2855
    • (1994) Cancer Res , vol.54 , Issue.11 , pp. 2852-2855
    • Shuin, T.1    Kondo, K.2    Torigoe, S.3
  • 51
    • 0015043748 scopus 로고
    • Mutation and cancer: statistical study of retinoblastoma
    • Knudson Jr. A.G. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 68 4 (1971) 820-823
    • (1971) Proc Natl Acad Sci U S A , vol.68 , Issue.4 , pp. 820-823
    • Knudson Jr., A.G.1
  • 52
    • 9144268968 scopus 로고    scopus 로고
    • Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location
    • Maranchie J.K., Afonso A., Albert P.S., et al. Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location. Hum Mutat 23 1 (2004) 40-46
    • (2004) Hum Mutat , vol.23 , Issue.1 , pp. 40-46
    • Maranchie, J.K.1    Afonso, A.2    Albert, P.S.3
  • 53
    • 0029126892 scopus 로고
    • Inhibition of transcription elongation by the VHL tumor suppressor protein
    • Duan D.R., Pause A., Burgess W.H., et al. Inhibition of transcription elongation by the VHL tumor suppressor protein. Science 269 5229 (1995) 1402-1406
    • (1995) Science , vol.269 , Issue.5229 , pp. 1402-1406
    • Duan, D.R.1    Pause, A.2    Burgess, W.H.3
  • 54
    • 0029147430 scopus 로고
    • Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C
    • Kibel A., Iliopoulos O., DeCaprio J.A., et al. Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C. Science 269 5229 (1995) 1444-1446
    • (1995) Science , vol.269 , Issue.5229 , pp. 1444-1446
    • Kibel, A.1    Iliopoulos, O.2    DeCaprio, J.A.3
  • 55
    • 0030953635 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
    • Pause A., Lee S., Worrell R.A., et al. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. Proc Natl Acad Sci U S A 94 6 (1997) 2156-2161
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.6 , pp. 2156-2161
    • Pause, A.1    Lee, S.2    Worrell, R.A.3
  • 56
    • 0032727343 scopus 로고    scopus 로고
    • The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2
    • Kamura T., Conrad M.N., Yan Q., et al. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2. Genes Dev 13 22 (1999) 2928-2933
    • (1999) Genes Dev , vol.13 , Issue.22 , pp. 2928-2933
    • Kamura, T.1    Conrad, M.N.2    Yan, Q.3
  • 57
    • 0029785321 scopus 로고    scopus 로고
    • Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein
    • Iliopoulos O., Levy A.P., Jiang C., et al. Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein. Proc Natl Acad Sci U S A 93 20 (1996) 10595-10599
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.20 , pp. 10595-10599
    • Iliopoulos, O.1    Levy, A.P.2    Jiang, C.3
  • 58
    • 0345164318 scopus 로고    scopus 로고
    • The VHL tumour-suppressor gene paradigm
    • Kaelin Jr. W.G., and Maher E.R. The VHL tumour-suppressor gene paradigm. Trends Genet 14 10 (1998) 423-426
    • (1998) Trends Genet , vol.14 , Issue.10 , pp. 423-426
    • Kaelin Jr., W.G.1    Maher, E.R.2
  • 59
    • 33746427905 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing
    • Kaelin W.G. The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing. Cold Spring Harb Symp Quant Biol 70 (2005) 159-166
    • (2005) Cold Spring Harb Symp Quant Biol , vol.70 , pp. 159-166
    • Kaelin, W.G.1
  • 60
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell P.H., Wiesener M.S., Chang G.W., et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 6733 (1999) 271-275
    • (1999) Nature , vol.399 , Issue.6733 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 61
    • 17944375360 scopus 로고    scopus 로고
    • C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
    • Epstein A.C., Gleadle J.M., McNeill L.A., et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107 1 (2001) 43-54
    • (2001) Cell , vol.107 , Issue.1 , pp. 43-54
    • Epstein, A.C.1    Gleadle, J.M.2    McNeill, L.A.3
  • 62
    • 0033776536 scopus 로고    scopus 로고
    • Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
    • Ohh M., Park C.W., Ivan M., et al. Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat Cell Biol 2 7 (2000) 423-427
    • (2000) Nat Cell Biol , vol.2 , Issue.7 , pp. 423-427
    • Ohh, M.1    Park, C.W.2    Ivan, M.3
  • 63
    • 23644448721 scopus 로고    scopus 로고
    • HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability
    • Isaacs J.S., Jung Y.J., Mole D.R., et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell 8 2 (2005) 143-153
    • (2005) Cancer Cell , vol.8 , Issue.2 , pp. 143-153
    • Isaacs, J.S.1    Jung, Y.J.2    Mole, D.R.3
  • 64
    • 0034682783 scopus 로고    scopus 로고
    • Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
    • Cockman M.E., Masson N., Mole D.R., et al. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J Biol Chem 275 33 (2000) 25733-25741
    • (2000) J Biol Chem , vol.275 , Issue.33 , pp. 25733-25741
    • Cockman, M.E.1    Masson, N.2    Mole, D.R.3
  • 65
    • 0036138398 scopus 로고    scopus 로고
    • Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing
    • Mole D.R., Maxwell P.H., Pugh C.W., et al. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing. IUBMB Life 52 1-2 (2001) 43-47
    • (2001) IUBMB Life , vol.52 , Issue.1-2 , pp. 43-47
    • Mole, D.R.1    Maxwell, P.H.2    Pugh, C.W.3
  • 66
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P., Mole D.R., Tian Y.M., et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292 5516 (2001) 468-472
    • (2001) Science , vol.292 , Issue.5516 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3
  • 67
    • 0035917313 scopus 로고    scopus 로고
    • HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
    • Ivan M., Kondo K., Yang H., et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292 5516 (2001) 464-468
    • (2001) Science , vol.292 , Issue.5516 , pp. 464-468
    • Ivan, M.1    Kondo, K.2    Yang, H.3
  • 68
    • 0037326037 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
    • Pugh C.W., and Ratcliffe P.J. The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Semin Cancer Biol 13 1 (2003) 83-89
    • (2003) Semin Cancer Biol , vol.13 , Issue.1 , pp. 83-89
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 69
    • 0034641615 scopus 로고    scopus 로고
    • Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex
    • Kamura T., Sato S., Iwai K., et al. Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex. Proc Natl Acad Sci U S A 97 19 (2000) 10430-10435
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.19 , pp. 10430-10435
    • Kamura, T.1    Sato, S.2    Iwai, K.3
  • 70
    • 0035852630 scopus 로고    scopus 로고
    • Role of transforming growth factor-alpha in von Hippel-Lindau (VHL) (-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis
    • de Paulsen N., Brychzy A., Fournier M.C., et al. Role of transforming growth factor-alpha in von Hippel-Lindau (VHL) (-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis. Proc Natl Acad Sci U S A 98 4 (2001) 1387-1392
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.4 , pp. 1387-1392
    • de Paulsen, N.1    Brychzy, A.2    Fournier, M.C.3
  • 71
    • 0036527785 scopus 로고    scopus 로고
    • The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma
    • Maranchie J.K., Vasselli J.R., Riss J., et al. The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma. Cancer Cell 1 3 (2002) 247-255
    • (2002) Cancer Cell , vol.1 , Issue.3 , pp. 247-255
    • Maranchie, J.K.1    Vasselli, J.R.2    Riss, J.3
  • 72
    • 0036528246 scopus 로고    scopus 로고
    • Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
    • Kondo K., Klco J., Nakamura E., et al. Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. Cancer Cell 1 3 (2002) 237-246
    • (2002) Cancer Cell , vol.1 , Issue.3 , pp. 237-246
    • Kondo, K.1    Klco, J.2    Nakamura, E.3
  • 73
    • 2342597973 scopus 로고    scopus 로고
    • Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth
    • Kondo K., Kim W.Y., Lechpammer M., et al. Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth. PLoS Biol 1 3 (2003) E83
    • (2003) PLoS Biol , vol.1 , Issue.3
    • Kondo, K.1    Kim, W.Y.2    Lechpammer, M.3
  • 74
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • Motzer R.J., Michaelson M.D., Redman B.G., et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 24 1 (2006) 16-24
    • (2006) J Clin Oncol , vol.24 , Issue.1 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 75
    • 1242271198 scopus 로고    scopus 로고
    • Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications
    • Rapisarda A., Uranchimeg B., Sordet O., et al. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res 64 4 (2004) 1475-1482
    • (2004) Cancer Res , vol.64 , Issue.4 , pp. 1475-1482
    • Rapisarda, A.1    Uranchimeg, B.2    Sordet, O.3
  • 76
    • 0037119415 scopus 로고    scopus 로고
    • Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway
    • Isaacs J.S., Jung Y.J., Mimnaugh E.G., et al. Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway. J Biol Chem 277 33 (2002) 29936-29944
    • (2002) J Biol Chem , vol.277 , Issue.33 , pp. 29936-29944
    • Isaacs, J.S.1    Jung, Y.J.2    Mimnaugh, E.G.3
  • 77
    • 0025741681 scopus 로고
    • Von Hippel-Lindau disease: a genetic study
    • Maher E.R., Iselius L., Yates J.R., et al. Von Hippel-Lindau disease: a genetic study. J Med Genet 28 7 (1991) 443-447
    • (1991) J Med Genet , vol.28 , Issue.7 , pp. 443-447
    • Maher, E.R.1    Iselius, L.2    Yates, J.R.3
  • 78
    • 0025863170 scopus 로고
    • Clustering of features of von Hippel-Lindau syndrome: evidence for a complex genetic locus
    • Neumann H.P., and Wiestler O.D. Clustering of features of von Hippel-Lindau syndrome: evidence for a complex genetic locus. Lancet 337 8749 (1991) 1052-1054
    • (1991) Lancet , vol.337 , Issue.8749 , pp. 1052-1054
    • Neumann, H.P.1    Wiestler, O.D.2
  • 79
    • 0029065453 scopus 로고
    • Treatment of renal cell carcinoma in von Hippel-Lindau disease: a multicenter study
    • Steinbach F., Novick A.C., Zincke H., et al. Treatment of renal cell carcinoma in von Hippel-Lindau disease: a multicenter study. J Urol 153 6 (1995) 1812-1816
    • (1995) J Urol , vol.153 , Issue.6 , pp. 1812-1816
    • Steinbach, F.1    Novick, A.C.2    Zincke, H.3
  • 80
    • 0026146897 scopus 로고
    • von Hippel-Lindau disease: a genetic condition predisposing tumor formation
    • Martz C.H. von Hippel-Lindau disease: a genetic condition predisposing tumor formation. Oncol Nurs Forum 18 3 (1991) 545-551
    • (1991) Oncol Nurs Forum , vol.18 , Issue.3 , pp. 545-551
    • Martz, C.H.1
  • 81
    • 0017155917 scopus 로고
    • Von Hippel-Lindau disease: clinical and pathological manifestations in nine families with 50 affected members
    • Horton W.A., Wong V., and Eldridge R. Von Hippel-Lindau disease: clinical and pathological manifestations in nine families with 50 affected members. Arch Intern Med 136 7 (1976) 769-777
    • (1976) Arch Intern Med , vol.136 , Issue.7 , pp. 769-777
    • Horton, W.A.1    Wong, V.2    Eldridge, R.3
  • 83
    • 0026078219 scopus 로고
    • Central nervous system involvement in von Hippel-Lindau disease
    • Filling-Katz M.R., Choyke P.L., Oldfield E., et al. Central nervous system involvement in von Hippel-Lindau disease. Neurology 41 1 (1991) 41-46
    • (1991) Neurology , vol.41 , Issue.1 , pp. 41-46
    • Filling-Katz, M.R.1    Choyke, P.L.2    Oldfield, E.3
  • 84
    • 0026658308 scopus 로고
    • Central nervous system lesions in von Hippel-Lindau syndrome
    • Neumann H.P., Eggert H.R., Scheremet R., et al. Central nervous system lesions in von Hippel-Lindau syndrome. J Neurol Neurosurg Psychiatry 55 10 (1992) 898-901
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , Issue.10 , pp. 898-901
    • Neumann, H.P.1    Eggert, H.R.2    Scheremet, R.3
  • 85
    • 0027971964 scopus 로고
    • Evaluation of color Doppler intraoperative ultrasound in parenchymal sparing renal surgery
    • Walther M.M., Choyke P.L., Hayes W., et al. Evaluation of color Doppler intraoperative ultrasound in parenchymal sparing renal surgery. J Urol 152 6 Pt 1 (1994) 1984-1987
    • (1994) J Urol , vol.152 , Issue.6 PART 1 , pp. 1984-1987
    • Walther, M.M.1    Choyke, P.L.2    Hayes, W.3
  • 86
    • 0025909364 scopus 로고
    • von Hippel-Lindau disease: inadequacy of angiography for identification of renal cancers
    • Miller D.L., Choyke P.L., Walther M.M., et al. von Hippel-Lindau disease: inadequacy of angiography for identification of renal cancers. Radiology 179 3 (1991) 833-836
    • (1991) Radiology , vol.179 , Issue.3 , pp. 833-836
    • Miller, D.L.1    Choyke, P.L.2    Walther, M.M.3
  • 87
    • 0019157375 scopus 로고
    • A plea for conservation of kidney in renal adenocarcinoma associated with von Hippel-Lindau disease
    • Pearson J.C., Weiss J., and Tanagho E.A. A plea for conservation of kidney in renal adenocarcinoma associated with von Hippel-Lindau disease. J Urol 124 6 (1980) 910-912
    • (1980) J Urol , vol.124 , Issue.6 , pp. 910-912
    • Pearson, J.C.1    Weiss, J.2    Tanagho, E.A.3
  • 88
    • 0022487177 scopus 로고
    • Urological management of patients with von Hippel-Lindau's disease
    • Loughlin K.R., and Gittes R.F. Urological management of patients with von Hippel-Lindau's disease. J Urol 136 4 (1986) 789-791
    • (1986) J Urol , vol.136 , Issue.4 , pp. 789-791
    • Loughlin, K.R.1    Gittes, R.F.2
  • 89
    • 0023614752 scopus 로고
    • Renal cell carcinoma in von Hippel-Lindau syndrome
    • Malek R.S., Omess P.J., Benson Jr. R.C., et al. Renal cell carcinoma in von Hippel-Lindau syndrome. Am J Med 82 2 (1987) 236-238
    • (1987) Am J Med , vol.82 , Issue.2 , pp. 236-238
    • Malek, R.S.1    Omess, P.J.2    Benson Jr., R.C.3
  • 90
    • 0028188645 scopus 로고
    • Renal lesions and pheochromocytoma in von Hippel-Lindau disease
    • Richard S., Chauveau D., Chretien Y., et al. Renal lesions and pheochromocytoma in von Hippel-Lindau disease. Adv Nephrol Necker Hosp 23 (1994) 1-27
    • (1994) Adv Nephrol Necker Hosp , vol.23 , pp. 1-27
    • Richard, S.1    Chauveau, D.2    Chretien, Y.3
  • 91
    • 0032322491 scopus 로고    scopus 로고
    • Prevalence, morphology and biology of renal cell carcinoma in von Hippel-Lindau disease compared to sporadic renal cell carcinoma
    • Neumann H.P., Bender B.U., Berger D.P., et al. Prevalence, morphology and biology of renal cell carcinoma in von Hippel-Lindau disease compared to sporadic renal cell carcinoma. J Urol 160 4 (1998) 1248-1254
    • (1998) J Urol , vol.160 , Issue.4 , pp. 1248-1254
    • Neumann, H.P.1    Bender, B.U.2    Berger, D.P.3
  • 92
    • 0028800884 scopus 로고
    • Prevalence of microscopic lesions in grossly normal renal parenchyma from patients with von Hippel-Lindau disease, sporadic renal cell carcinoma and no renal disease: clinical implications
    • [discussion: 2014-5]
    • Walther M.M., Lubensky I.A., Venzon D., et al. Prevalence of microscopic lesions in grossly normal renal parenchyma from patients with von Hippel-Lindau disease, sporadic renal cell carcinoma and no renal disease: clinical implications. J Urol 154 6 (1995) 2010-2014 [discussion: 2014-5]
    • (1995) J Urol , vol.154 , Issue.6 , pp. 2010-2014
    • Walther, M.M.1    Lubensky, I.A.2    Venzon, D.3
  • 93
    • 0029446541 scopus 로고
    • Enucleation procedures in patients with multiple hereditary renal tumors
    • Walther M.M., Thompson N., and Linehan W. Enucleation procedures in patients with multiple hereditary renal tumors. World J Urol 13 4 (1995) 248-250
    • (1995) World J Urol , vol.13 , Issue.4 , pp. 248-250
    • Walther, M.M.1    Thompson, N.2    Linehan, W.3
  • 94
    • 3242765340 scopus 로고    scopus 로고
    • The relationship between renal tumor size and metastases in patients with von Hippel-Lindau disease
    • Duffey B.G., Choyke P.L., Glenn G., et al. The relationship between renal tumor size and metastases in patients with von Hippel-Lindau disease. J Urol 172 1 (2004) 63-65
    • (2004) J Urol , vol.172 , Issue.1 , pp. 63-65
    • Duffey, B.G.1    Choyke, P.L.2    Glenn, G.3
  • 95
    • 0017371320 scopus 로고
    • Bilateral renal cell carcinoma in von Hippel-Lindau syndrome: treatment with staged bilateral nephrectomy and hemodialysis
    • Fetner C.D., Barilla D.E., Scott T., et al. Bilateral renal cell carcinoma in von Hippel-Lindau syndrome: treatment with staged bilateral nephrectomy and hemodialysis. J Urol 117 4 (1977) 534-536
    • (1977) J Urol , vol.117 , Issue.4 , pp. 534-536
    • Fetner, C.D.1    Barilla, D.E.2    Scott, T.3
  • 96
    • 0020699755 scopus 로고
    • Diagnosis and management of asymptomatic renal cell carcinomas in von Hippel-Lindau syndrome
    • Levine E., Weigel J.W., and Collins D.L. Diagnosis and management of asymptomatic renal cell carcinomas in von Hippel-Lindau syndrome. Urology 21 2 (1983) 146-150
    • (1983) Urology , vol.21 , Issue.2 , pp. 146-150
    • Levine, E.1    Weigel, J.W.2    Collins, D.L.3
  • 97
    • 0023864590 scopus 로고
    • Surgical treatment of localized renal cell carcinoma in von Hippel-Lindau's disease
    • Spencer W.F., Novick A.C., Montie J.E., et al. Surgical treatment of localized renal cell carcinoma in von Hippel-Lindau's disease. J Urol 139 3 (1988) 507-509
    • (1988) J Urol , vol.139 , Issue.3 , pp. 507-509
    • Spencer, W.F.1    Novick, A.C.2    Montie, J.E.3
  • 98
    • 0031463374 scopus 로고    scopus 로고
    • Results of renal transplantation in patients with renal cell carcinoma and von Hippel-Lindau disease
    • Goldfarb D.A., Neumann H.P., Penn I., et al. Results of renal transplantation in patients with renal cell carcinoma and von Hippel-Lindau disease. Transplantation 64 12 (1997) 1726-1729
    • (1997) Transplantation , vol.64 , Issue.12 , pp. 1726-1729
    • Goldfarb, D.A.1    Neumann, H.P.2    Penn, I.3
  • 99
    • 0141919747 scopus 로고    scopus 로고
    • Nephron sparing surgery for renal cell carcinoma and von Hippel-Lindau's disease: a single center experience
    • Roupret M., Hopirtean V., Mejean A., et al. Nephron sparing surgery for renal cell carcinoma and von Hippel-Lindau's disease: a single center experience. J Urol 170 5 (2003) 1752-1755
    • (2003) J Urol , vol.170 , Issue.5 , pp. 1752-1755
    • Roupret, M.1    Hopirtean, V.2    Mejean, A.3
  • 100
    • 34848864569 scopus 로고    scopus 로고
    • Local recurrence after nephron-sparing surgery in von-Hippel-Lindau disease
    • Ploussard G., Droupy S., Ferlicot S., et al. Local recurrence after nephron-sparing surgery in von-Hippel-Lindau disease. Urology 70 3 (2007) 435-439
    • (2007) Urology , vol.70 , Issue.3 , pp. 435-439
    • Ploussard, G.1    Droupy, S.2    Ferlicot, S.3
  • 101
    • 36849078165 scopus 로고    scopus 로고
    • Salvage partial nephrectomy for hereditary renal cancer: feasibility and outcomes
    • Bratslavsky G., Liu J.J., Ferlicot S., et al. Salvage partial nephrectomy for hereditary renal cancer: feasibility and outcomes. J Urol 179 1 (2008) 67-70
    • (2008) J Urol , vol.179 , Issue.1 , pp. 67-70
    • Bratslavsky, G.1    Liu, J.J.2    Ferlicot, S.3
  • 102
    • 39149126670 scopus 로고    scopus 로고
    • Analysis of repeat nephron sparing surgery as a treatment option in patients with a solid mass in a renal remnant
    • Magera Jr. J.S., Frank I., Lohse C.M., et al. Analysis of repeat nephron sparing surgery as a treatment option in patients with a solid mass in a renal remnant. J Urol 179 3 (2008) 853-856
    • (2008) J Urol , vol.179 , Issue.3 , pp. 853-856
    • Magera Jr., J.S.1    Frank, I.2    Lohse, C.M.3
  • 103
    • 2442555973 scopus 로고    scopus 로고
    • Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience
    • [quiz 2435]
    • Patard J.J., Shvarts O., Lam J.S., et al. Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience. J Urol 171 6 Pt 1 (2004) 2181-2185 [quiz 2435]
    • (2004) J Urol , vol.171 , Issue.6 PART 1 , pp. 2181-2185
    • Patard, J.J.1    Shvarts, O.2    Lam, J.S.3
  • 104
    • 23744489542 scopus 로고    scopus 로고
    • Complications of contemporary open nephron sparing surgery: a single institution experience
    • Thompson R.H., Leibovich B.C., Lohse C.M., et al. Complications of contemporary open nephron sparing surgery: a single institution experience. J Urol 174 3 (2005) 855-858
    • (2005) J Urol , vol.174 , Issue.3 , pp. 855-858
    • Thompson, R.H.1    Leibovich, B.C.2    Lohse, C.M.3
  • 105
    • 40849102328 scopus 로고    scopus 로고
    • Excise, ablate or observe: the small renal mass dilemma-a meta-analysis and review
    • Kunkle D.A., Egleston B.L., and Uzzo R.G. Excise, ablate or observe: the small renal mass dilemma-a meta-analysis and review. J Urol 179 4 (2008) 1227-1233
    • (2008) J Urol , vol.179 , Issue.4 , pp. 1227-1233
    • Kunkle, D.A.1    Egleston, B.L.2    Uzzo, R.G.3
  • 106
    • 33845586263 scopus 로고    scopus 로고
    • Minimally invasive nephron-sparing surgery (MINSS) for renal tumours. Part II: probe ablative therapy
    • Aron M., and Gill I.S. Minimally invasive nephron-sparing surgery (MINSS) for renal tumours. Part II: probe ablative therapy. Eur Urol 51 2 (2007) 348-357
    • (2007) Eur Urol , vol.51 , Issue.2 , pp. 348-357
    • Aron, M.1    Gill, I.S.2
  • 107
    • 4444234207 scopus 로고    scopus 로고
    • Radiofrequency ablation of renal tumors
    • Mahnken A.H., Gunther R.W., and Tacke J. Radiofrequency ablation of renal tumors. Eur Radiol 14 8 (2004) 1449-1455
    • (2004) Eur Radiol , vol.14 , Issue.8 , pp. 1449-1455
    • Mahnken, A.H.1    Gunther, R.W.2    Tacke, J.3
  • 108
    • 6544234532 scopus 로고    scopus 로고
    • Clinical and genetic characterization of pheochromocytoma in von Hippel-Lindau families: comparison with sporadic pheochromocytoma gives insight into natural history of pheochromocytoma
    • Walther M.M., Reiter R., Keiser H.R., et al. Clinical and genetic characterization of pheochromocytoma in von Hippel-Lindau families: comparison with sporadic pheochromocytoma gives insight into natural history of pheochromocytoma. J Urol 162 3 Pt 1 (1999) 659-664
    • (1999) J Urol , vol.162 , Issue.3 PART 1 , pp. 659-664
    • Walther, M.M.1    Reiter, R.2    Keiser, H.R.3
  • 109
    • 0025807163 scopus 로고
    • Von Hippel-Lindau (VHL) disease: distinct phenotypes suggest more than one mutant allele at the VHL locus
    • Glenn G.M., Daniel L.N., Choyke P., et al. Von Hippel-Lindau (VHL) disease: distinct phenotypes suggest more than one mutant allele at the VHL locus. Hum Genet 87 2 (1991) 207-210
    • (1991) Hum Genet , vol.87 , Issue.2 , pp. 207-210
    • Glenn, G.M.1    Daniel, L.N.2    Choyke, P.3
  • 110
    • 0028981766 scopus 로고
    • Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype
    • Chen F., Kishida T., Yao M., et al. Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype. Hum Mutat 5 1 (1995) 66-75
    • (1995) Hum Mutat , vol.5 , Issue.1 , pp. 66-75
    • Chen, F.1    Kishida, T.2    Yao, M.3
  • 111
    • 0028205824 scopus 로고
    • Silent adrenal nodules in von Hippel-Lindau disease suggest pheochromocytoma
    • Aprill B.S., Drake III A.J., Lasseter D.H., et al. Silent adrenal nodules in von Hippel-Lindau disease suggest pheochromocytoma. Ann Intern Med 120 6 (1994) 485-487
    • (1994) Ann Intern Med , vol.120 , Issue.6 , pp. 485-487
    • Aprill, B.S.1    Drake III, A.J.2    Lasseter, D.H.3
  • 112
    • 0024951884 scopus 로고
    • Quality of life after bilateral adrenalectomy in MEN 2
    • Telenius-Berg M., Ponder M.A., Berg B., et al. Quality of life after bilateral adrenalectomy in MEN 2. Henry Ford Hosp Med J 37 3-4 (1989) 160-163
    • (1989) Henry Ford Hosp Med J , vol.37 , Issue.3-4 , pp. 160-163
    • Telenius-Berg, M.1    Ponder, M.A.2    Berg, B.3
  • 113
    • 0033072719 scopus 로고    scopus 로고
    • Management of hereditary pheochromocytoma in von Hippel-Lindau kindreds with partial adrenalectomy
    • Walther M.M., Keiser H.R., Choyke P.L., et al. Management of hereditary pheochromocytoma in von Hippel-Lindau kindreds with partial adrenalectomy. J Urol 161 2 (1999) 395-398
    • (1999) J Urol , vol.161 , Issue.2 , pp. 395-398
    • Walther, M.M.1    Keiser, H.R.2    Choyke, P.L.3
  • 114
    • 0003079013 scopus 로고
    • Papillary cystadenomas of the epididymis and spermatic cord
    • Meyer J.S., Roth L.M., and Silverman J.L. Papillary cystadenomas of the epididymis and spermatic cord. Cancer 17 (1964) 1241-1247
    • (1964) Cancer , vol.17 , pp. 1241-1247
    • Meyer, J.S.1    Roth, L.M.2    Silverman, J.L.3
  • 115
    • 0015062093 scopus 로고
    • Papillary cystadenoma of the epididymis. A clinicopathologic analysis of 20 cases
    • Price Jr. E.B. Papillary cystadenoma of the epididymis. A clinicopathologic analysis of 20 cases. Arch Pathol 91 5 (1971) 456-470
    • (1971) Arch Pathol , vol.91 , Issue.5 , pp. 456-470
    • Price Jr., E.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.