-
1
-
-
8844264504
-
Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity
-
Aithal G.P. Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity. Expert Opin. Drug Saf. 3 (2004) 519-523
-
(2004)
Expert Opin. Drug Saf.
, vol.3
, pp. 519-523
-
-
Aithal, G.P.1
-
2
-
-
2342541211
-
Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity
-
Aithal G.P., Ramsay L., Daly A.K., Sonchit N., Leathart J.B., Alexander G., Kenna J.G., Caldwell J., and Day C.P. Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity. Hepatology 39 (2004) 1430-1440
-
(2004)
Hepatology
, vol.39
, pp. 1430-1440
-
-
Aithal, G.P.1
Ramsay, L.2
Daly, A.K.3
Sonchit, N.4
Leathart, J.B.5
Alexander, G.6
Kenna, J.G.7
Caldwell, J.8
Day, C.P.9
-
3
-
-
19544375394
-
Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1
-
Alvarez L., Jara P., Sanchez-Sabate E., Hierro L., Larrauri J., Diaz M.C., Camarena C., De la Vega A., Frauca E., Lopez-Collazo E., and Lapunzina P. Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1. Hum. Mol. Genet. 13 (2004) 2451-2460
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2451-2460
-
-
Alvarez, L.1
Jara, P.2
Sanchez-Sabate, E.3
Hierro, L.4
Larrauri, J.5
Diaz, M.C.6
Camarena, C.7
De la Vega, A.8
Frauca, E.9
Lopez-Collazo, E.10
Lapunzina, P.11
-
4
-
-
2542627509
-
HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease
-
Andrade R.J., Lucena M.I., Alonso A., Garcia-Cortes M., Garcia-Ruiz E., Benitez R., Fernandez M.C., Pelaez G., Romero M., Corpas R., Duran J.A., Jimenez M., Rodrigo L., Nogueras F., Martin-Vivaldi R., Navarro J.M., Salmeron J., de la Cuesta F.S., and Hidalgo R. HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease. Hepatology 39 (2004) 1603-1612
-
(2004)
Hepatology
, vol.39
, pp. 1603-1612
-
-
Andrade, R.J.1
Lucena, M.I.2
Alonso, A.3
Garcia-Cortes, M.4
Garcia-Ruiz, E.5
Benitez, R.6
Fernandez, M.C.7
Pelaez, G.8
Romero, M.9
Corpas, R.10
Duran, J.A.11
Jimenez, M.12
Rodrigo, L.13
Nogueras, F.14
Martin-Vivaldi, R.15
Navarro, J.M.16
Salmeron, J.17
de la Cuesta, F.S.18
Hidalgo, R.19
-
5
-
-
30844460667
-
OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia
-
Ballatori N., Christian W.V., Lee J.Y., Dawson P.A., Soroka C.J., Boyer J.L., Madejczyk M.S., and Li N. OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology 42 (2005) 1270-1279
-
(2005)
Hepatology
, vol.42
, pp. 1270-1279
-
-
Ballatori, N.1
Christian, W.V.2
Lee, J.Y.3
Dawson, P.A.4
Soroka, C.J.5
Boyer, J.L.6
Madejczyk, M.S.7
Li, N.8
-
6
-
-
22344446049
-
Analysis of the in vivo functions of Mrp3
-
Belinsky M.G., Dawson P.A., Shchaveleva I., Bain L.J., Wang R., Ling V., Chen Z.S., Grinberg A., Westphal H., Klein-Szanto A., Lerro A., and Kruh G.D. Analysis of the in vivo functions of Mrp3. Mol. Pharmacol. 68 (2005) 160-168
-
(2005)
Mol. Pharmacol.
, vol.68
, pp. 160-168
-
-
Belinsky, M.G.1
Dawson, P.A.2
Shchaveleva, I.3
Bain, L.J.4
Wang, R.5
Ling, V.6
Chen, Z.S.7
Grinberg, A.8
Westphal, H.9
Klein-Szanto, A.10
Lerro, A.11
Kruh, G.D.12
-
7
-
-
0036256463
-
Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions
-
Bohan A., and Boyer J.L. Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions. Semin. Liver Dis. 22 (2002) 123-136
-
(2002)
Semin. Liver Dis.
, vol.22
, pp. 123-136
-
-
Bohan, A.1
Boyer, J.L.2
-
8
-
-
0036247148
-
Hepatotoxicity of antimicrobial agents
-
Brown S.J., and Desmond P.V. Hepatotoxicity of antimicrobial agents. Semin. Liver Dis. 22 (2002) 157-167
-
(2002)
Semin. Liver Dis.
, vol.22
, pp. 157-167
-
-
Brown, S.J.1
Desmond, P.V.2
-
9
-
-
0031907132
-
A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis
-
Bull L.N., van Eijk M.J., Pawlikowska L., DeYoung J.A., Juijn J.A., Liao M., Klomp L.W., Lomri N., Berger R., Scharschmidt B.F., Knisely A.S., Houwen R.H., and Freimer N.B. A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis. Nat. Genet. 18 (1998) 219-224
-
(1998)
Nat. Genet.
, vol.18
, pp. 219-224
-
-
Bull, L.N.1
van Eijk, M.J.2
Pawlikowska, L.3
DeYoung, J.A.4
Juijn, J.A.5
Liao, M.6
Klomp, L.W.7
Lomri, N.8
Berger, R.9
Scharschmidt, B.F.10
Knisely, A.S.11
Houwen, R.H.12
Freimer, N.B.13
-
10
-
-
27444444430
-
Immunochemical detection of flucloxacillin adduct formation in livers of treated rats
-
Carey M.A., and van Pelt F.N. Immunochemical detection of flucloxacillin adduct formation in livers of treated rats. Toxicology 216 (2005) 41-48
-
(2005)
Toxicology
, vol.216
, pp. 41-48
-
-
Carey, M.A.1
van Pelt, F.N.2
-
11
-
-
0036668184
-
Bile acid regulation of gene expression: roles of nuclear hormone receptors
-
Chiang J.Y. Bile acid regulation of gene expression: roles of nuclear hormone receptors. Endocr. Rev. 23 (2002) 443-463
-
(2002)
Endocr. Rev.
, vol.23
, pp. 443-463
-
-
Chiang, J.Y.1
-
13
-
-
33846230114
-
Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes
-
Daly A.K., Aithal G.P., Leathart J.B., Swainsbury R.A., Dang T.S., and Day C.P. Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology 132 (2007) 272-281
-
(2007)
Gastroenterology
, vol.132
, pp. 272-281
-
-
Daly, A.K.1
Aithal, G.P.2
Leathart, J.B.3
Swainsbury, R.A.4
Dang, T.S.5
Day, C.P.6
-
15
-
-
0028845801
-
Flucloxacillin associated cholestatic hepatitis. An Australian and Swedish epidemic?
-
Devereaux B.M., Crawford D.H., Purcell P., Powell L.W., and Roeser H.P. Flucloxacillin associated cholestatic hepatitis. An Australian and Swedish epidemic?. Eur. J. Clin. Pharmacol. 49 (1995) 81-85
-
(1995)
Eur. J. Clin. Pharmacol.
, vol.49
, pp. 81-85
-
-
Devereaux, B.M.1
Crawford, D.H.2
Purcell, P.3
Powell, L.W.4
Roeser, H.P.5
-
16
-
-
32044444072
-
The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease
-
(quiz 592)
-
Dring M.M., Goulding C.A., Trimble V.I., Keegan D., Ryan A.W., Brophy K.M., Smyth C.M., Keeling P.W., O'Donoghue D., O'Sullivan M., O'Morain C., Mahmud N., Wikstrom A.C., Kelleher D., and McManus R. The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease. Gastroenterology 130 (2006) 341-348 (quiz 592)
-
(2006)
Gastroenterology
, vol.130
, pp. 341-348
-
-
Dring, M.M.1
Goulding, C.A.2
Trimble, V.I.3
Keegan, D.4
Ryan, A.W.5
Brophy, K.M.6
Smyth, C.M.7
Keeling, P.W.8
O'Donoghue, D.9
O'Sullivan, M.10
O'Morain, C.11
Mahmud, N.12
Wikstrom, A.C.13
Kelleher, D.14
McManus, R.15
-
17
-
-
0037407770
-
Cholestasis
-
ii42-8
-
Elferink R.O. Cholestasis. Gut 52 Suppl. 2 (2003) ii42-8
-
(2003)
Gut
, vol.52
, Issue.SUPPL. 2
-
-
Elferink, R.O.1
-
18
-
-
0034798633
-
FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte
-
Eppens E.F., van Mil S.W., de Vree J.M., Mok K.S., Juijn J.A., Oude Elferink R.P., Berger R., Houwen R.H., and Klomp L.W. FIC1, the protein affected in two forms of hereditary cholestasis, is localized in the cholangiocyte and the canalicular membrane of the hepatocyte. J. Hepatol. 35 (2001) 436-443
-
(2001)
J. Hepatol.
, vol.35
, pp. 436-443
-
-
Eppens, E.F.1
van Mil, S.W.2
de Vree, J.M.3
Mok, K.S.4
Juijn, J.A.5
Oude Elferink, R.P.6
Berger, R.7
Houwen, R.H.8
Klomp, L.W.9
-
19
-
-
0027507344
-
Risk factors for development of flucloxacillin associated jaundice
-
Fairley C.K., McNeil J.J., Desmond P., Smallwood R., Young H., Forbes A., Purcell P., and Boyd I. Risk factors for development of flucloxacillin associated jaundice. BMJ 306 (1993) 233-235
-
(1993)
BMJ
, vol.306
, pp. 233-235
-
-
Fairley, C.K.1
McNeil, J.J.2
Desmond, P.3
Smallwood, R.4
Young, H.5
Forbes, A.6
Purcell, P.7
Boyd, I.8
-
20
-
-
0030027622
-
+/bile acid cotransporter in extrahepatic cholestasis
-
+/bile acid cotransporter in extrahepatic cholestasis. Gastroenterology 110 (1996) 199-209
-
(1996)
Gastroenterology
, vol.110
, pp. 199-209
-
-
Gartung, C.1
Ananthanarayanan, M.2
Rahman, M.A.3
Schuele, S.4
Nundy, S.5
Soroka, C.J.6
Stolz, A.7
Suchy, F.J.8
Boyer, J.L.9
-
21
-
-
6944234902
-
Regulation of CYP3A4 by the bile acid receptor FXR: evidence for functional binding sites in the CYP3A4 gene
-
Gnerre C., Blattler S., Kaufmann M.R., Looser R., and Meyer U.A. Regulation of CYP3A4 by the bile acid receptor FXR: evidence for functional binding sites in the CYP3A4 gene. Pharmacogenetics 14 (2004) 635-645
-
(2004)
Pharmacogenetics
, vol.14
, pp. 635-645
-
-
Gnerre, C.1
Blattler, S.2
Kaufmann, M.R.3
Looser, R.4
Meyer, U.A.5
-
22
-
-
0032738987
-
HLA association of amoxicillin-clavulanate-induced hepatitis
-
Hautekeete M.L., Horsmans Y., Van Waeyenberge C., Demanet C., Henrion J., Verbist L., Brenard R., Sempoux C., Michielsen P.P., Yap P.S., Rahier J., and Geubel A.P. HLA association of amoxicillin-clavulanate-induced hepatitis. Gastroenterology 117 (1999) 1181-1186
-
(1999)
Gastroenterology
, vol.117
, pp. 1181-1186
-
-
Hautekeete, M.L.1
Horsmans, Y.2
Van Waeyenberge, C.3
Demanet, C.4
Henrion, J.5
Verbist, L.6
Brenard, R.7
Sempoux, C.8
Michielsen, P.P.9
Yap, P.S.10
Rahier, J.11
Geubel, A.P.12
-
23
-
-
33644879162
-
Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin
-
Huwyler J., Wright M.B., Gutmann H., and Drewe J. Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin. Curr. Drug Metab. 7 (2006) 119-126
-
(2006)
Curr. Drug Metab.
, vol.7
, pp. 119-126
-
-
Huwyler, J.1
Wright, M.B.2
Gutmann, H.3
Drewe, J.4
-
24
-
-
20844444779
-
Idiosyncratic drug hepatotoxicity
-
Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat. Rev. Drug Discov. 4 (2005) 489-499
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 489-499
-
-
Kaplowitz, N.1
-
26
-
-
33646016599
-
Bile acid reabsorption inhibitors (BARI): novel hypolipidemic drugs
-
Kramer W G.H. Bile acid reabsorption inhibitors (BARI): novel hypolipidemic drugs. Curr. Med. Chem. 13 (2006) 997-1061
-
(2006)
Curr. Med. Chem.
, vol.13
, pp. 997-1061
-
-
Kramer W, G.H.1
-
27
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
Kuehl P., Zhang J., Lin Y., Lamba J., Assem M., Schuetz J., Watkins P.B., Daly A., Wrighton S.A., Hall S.D., Maurel P., Relling M., Brimer C., Yasuda K., Venkataramanan R., Strom S., Thummel K., Boguski M.S., and Schuetz E. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat. Genet. 27 (2001) 383-391
-
(2001)
Nat. Genet.
, vol.27
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
Lamba, J.4
Assem, M.5
Schuetz, J.6
Watkins, P.B.7
Daly, A.8
Wrighton, S.A.9
Hall, S.D.10
Maurel, P.11
Relling, M.12
Brimer, C.13
Yasuda, K.14
Venkataramanan, R.15
Strom, S.16
Thummel, K.17
Boguski, M.S.18
Schuetz, E.19
-
28
-
-
0034973781
-
Indirect cytotoxicity of flucloxacillin toward human biliary epithelium via metabolite formation in hepatocytes
-
Lakehal F., Dansette P.M., Becquemont L., Lasnier E., Delelo R., Balladur P., Poupon R., Beaune P.H., and Housset C. Indirect cytotoxicity of flucloxacillin toward human biliary epithelium via metabolite formation in hepatocytes. Chem. Res. Toxicol. 14 (2001) 694-701
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 694-701
-
-
Lakehal, F.1
Dansette, P.M.2
Becquemont, L.3
Lasnier, E.4
Delelo, R.5
Balladur, P.6
Poupon, R.7
Beaune, P.H.8
Housset, C.9
-
29
-
-
33645876468
-
MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype
-
Lamba J., Strom S., Venkataramanan R., Thummel K.E., Lin Y.S., Liu W., Cheng C., Lamba V., Watkins P.B., and Schuetz E. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype. Clin. Pharmacol. Ther. 79 (2006) 325-338
-
(2006)
Clin. Pharmacol. Ther.
, vol.79
, pp. 325-338
-
-
Lamba, J.1
Strom, S.2
Venkataramanan, R.3
Thummel, K.E.4
Lin, Y.S.5
Liu, W.6
Cheng, C.7
Lamba, V.8
Watkins, P.B.9
Schuetz, E.10
-
30
-
-
33846589652
-
Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury
-
Lang C., Meier Y., Stieger B., Beuers U., Lang T., Kerb R., Kullak-Ublick G.A., Meier P.J., and Pauli-Magnus C. Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury. Pharmacogenet. Genom. 17 (2007) 47-60
-
(2007)
Pharmacogenet. Genom.
, vol.17
, pp. 47-60
-
-
Lang, C.1
Meier, Y.2
Stieger, B.3
Beuers, U.4
Lang, T.5
Kerb, R.6
Kullak-Ublick, G.A.7
Meier, P.J.8
Pauli-Magnus, C.9
-
31
-
-
33845478161
-
Investigations toward enhanced understanding of hepatic idiosyncratic drug reactions
-
Liguori M.J., and Waring J.F. Investigations toward enhanced understanding of hepatic idiosyncratic drug reactions. Expert Opin. Drug Metab. Toxicol. 2 (2006) 835-846
-
(2006)
Expert Opin. Drug Metab. Toxicol.
, vol.2
, pp. 835-846
-
-
Liguori, M.J.1
Waring, J.F.2
-
32
-
-
0036089341
-
Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism
-
Lin Y.S., Dowling A.L., Quigley S.D., Farin F.M., Zhang J., Lamba J., Schuetz E.G., and Thummel K.E. Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. Mol. Pharmacol. 62 (2002) 162-172
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 162-172
-
-
Lin, Y.S.1
Dowling, A.L.2
Quigley, S.D.3
Farin, F.M.4
Zhang, J.5
Lamba, J.6
Schuetz, E.G.7
Thummel, K.E.8
-
34
-
-
9844252868
-
Diagnostic value of specific T cell reactivity to drugs in 95 cases of drug induced liver injury
-
Maria V.A., and Victorino R.M. Diagnostic value of specific T cell reactivity to drugs in 95 cases of drug induced liver injury. Gut 41 (1997) 534-540
-
(1997)
Gut
, vol.41
, pp. 534-540
-
-
Maria, V.A.1
Victorino, R.M.2
-
35
-
-
0033559723
-
Postmarketing surveillance: strengths and limitations. The flucloxacillin-dicloxacillin story
-
McNeil J.J., Grabsch E.A., and McDonald M.M. Postmarketing surveillance: strengths and limitations. The flucloxacillin-dicloxacillin story. Med. J. Aust. 170 (1999) 270-273
-
(1999)
Med. J. Aust.
, vol.170
, pp. 270-273
-
-
McNeil, J.J.1
Grabsch, E.A.2
McDonald, M.M.3
-
37
-
-
21144447029
-
ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy
-
Mullenbach R., Bennett A., Tetlow N., Patel N., Hamilton G., Cheng F., Chambers J., Howard R., Taylor-Robinson S.D., and Williamson C. ATP8B1 mutations in British cases with intrahepatic cholestasis of pregnancy. Gut 54 (2005) 829-834
-
(2005)
Gut
, vol.54
, pp. 829-834
-
-
Mullenbach, R.1
Bennett, A.2
Tetlow, N.3
Patel, N.4
Hamilton, G.5
Cheng, F.6
Chambers, J.7
Howard, R.8
Taylor-Robinson, S.D.9
Williamson, C.10
-
38
-
-
21844468483
-
Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis
-
Noe J., Kullak-Ublick G.A., Jochum W., Stieger B., Kerb R., Haberl M., Mullhaupt B., Meier P.J., and Pauli-Magnus C. Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis. J. Hepatol. 43 (2005) 536-543
-
(2005)
J. Hepatol.
, vol.43
, pp. 536-543
-
-
Noe, J.1
Kullak-Ublick, G.A.2
Jochum, W.3
Stieger, B.4
Kerb, R.5
Haberl, M.6
Mullhaupt, B.7
Meier, P.J.8
Pauli-Magnus, C.9
-
39
-
-
0033756344
-
Co-amoxiclav jaundice: clinical and histological features and HLA class II association
-
O'Donohue J., Oien K.A., Donaldson P., Underhill J., Clare M., MacSween R.N., and Mills P.R. Co-amoxiclav jaundice: clinical and histological features and HLA class II association. Gut 47 (2000) 717-720
-
(2000)
Gut
, vol.47
, pp. 717-720
-
-
O'Donohue, J.1
Oien, K.A.2
Donaldson, P.3
Underhill, J.4
Clare, M.5
MacSween, R.N.6
Mills, P.R.7
-
40
-
-
44649186853
-
Analysis of IL-10, IL-4 and TNFalpha polymorphisms in drug induced liver injury (DILI)
-
Pachkoria K., Lucena M.I., Crespo E., Ruiz-Cabello F., Lopez-Ortega S., Fernandez M.C., Romero-Gomez M., Madrazo A., Duran J.A., Malcon de Dios A., Borraz Y., Navarro J.M., Andrade R.J., and Disease S.G.f.t.S.o.D.I.L. Analysis of IL-10, IL-4 and TNFalpha polymorphisms in drug induced liver injury (DILI). J. Hepatol. 49 (2008) 107-114
-
(2008)
J. Hepatol.
, vol.49
, pp. 107-114
-
-
Pachkoria, K.1
Lucena, M.I.2
Crespo, E.3
Ruiz-Cabello, F.4
Lopez-Ortega, S.5
Fernandez, M.C.6
Romero-Gomez, M.7
Madrazo, A.8
Duran, J.A.9
Malcon de Dios, A.10
Borraz, Y.11
Navarro, J.M.12
Andrade, R.J.13
-
41
-
-
0029012444
-
Apoptosis and hepatobiliary disease
-
Patel T., and Gores G.J. Apoptosis and hepatobiliary disease. Hepatology 21 (1995) 1725-1741
-
(1995)
Hepatology
, vol.21
, pp. 1725-1741
-
-
Patel, T.1
Gores, G.J.2
-
42
-
-
21844436858
-
Enterohepatic transport of bile salts and genetics of cholestasis
-
Pauli-Magnus C., Stieger B., Meier Y., Kullak-Ublick G.A., and Meier P.J. Enterohepatic transport of bile salts and genetics of cholestasis. J. Hepatol. 43 (2005) 342-357
-
(2005)
J. Hepatol.
, vol.43
, pp. 342-357
-
-
Pauli-Magnus, C.1
Stieger, B.2
Meier, Y.3
Kullak-Ublick, G.A.4
Meier, P.J.5
-
43
-
-
11144355538
-
A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion
-
Pawlikowska L., Groen A., Eppens E.F., Kunne C., Ottenhoff R., Looije N., Knisely A.S., Killeen N.P., Bull L.N., Elferink R.P., and Freimer N.B. A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion. Hum. Mol. Genet. 13 (2004) 881-892
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 881-892
-
-
Pawlikowska, L.1
Groen, A.2
Eppens, E.F.3
Kunne, C.4
Ottenhoff, R.5
Looije, N.6
Knisely, A.S.7
Killeen, N.P.8
Bull, L.N.9
Elferink, R.P.10
Freimer, N.B.11
-
44
-
-
21744447422
-
Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database
-
Russmann S., Kaye J.A., Jick S.S., and Jick H. Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database. Br. J. Clin. Pharmacol. 60 (2005) 76-82
-
(2005)
Br. J. Clin. Pharmacol.
, vol.60
, pp. 76-82
-
-
Russmann, S.1
Kaye, J.A.2
Jick, S.S.3
Jick, H.4
-
45
-
-
0030059953
-
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in the human colon carcinoma cells
-
Schuetz E.G., Beck W.T., and Schuetz J.D. Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in the human colon carcinoma cells. Mol. Pharmacol. 49 (1996) 311-318
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 311-318
-
-
Schuetz, E.G.1
Beck, W.T.2
Schuetz, J.D.3
-
46
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal C.J., Tohkin M., Miyata M., Ward J.M., Lambert G., and Gonzalez F.J. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102 (2000) 731-744
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
47
-
-
13844315320
-
Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury
-
Stedman C.A., Liddle C., Coulter S.A., Sonoda J., Alvarez J.G., Moore D.D., Evans R.M., and Downes M. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 2063-2068
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2063-2068
-
-
Stedman, C.A.1
Liddle, C.2
Coulter, S.A.3
Sonoda, J.4
Alvarez, J.G.5
Moore, D.D.6
Evans, R.M.7
Downes, M.8
-
48
-
-
0018596689
-
Identification of the active metabolites of the isoxazolyl penicillins by means of mass-spectrometry
-
Thijssen H.H. Identification of the active metabolites of the isoxazolyl penicillins by means of mass-spectrometry. J. Antibiot. 32 (1979) 1033-1037
-
(1979)
J. Antibiot.
, vol.32
, pp. 1033-1037
-
-
Thijssen, H.H.1
-
49
-
-
0019133814
-
Analysis of isoxazolyl penicillins and their metabolites in body fluids by high-performance liquid chromatography
-
Thijssen H.H. Analysis of isoxazolyl penicillins and their metabolites in body fluids by high-performance liquid chromatography. J. Chromatogr. 183 (1980) 339-345
-
(1980)
J. Chromatogr.
, vol.183
, pp. 339-345
-
-
Thijssen, H.H.1
-
50
-
-
0019998179
-
The metabolic disposition of flucloxacillin in patients with impaired kidney function
-
Thijssen H.H., and Wolters J. The metabolic disposition of flucloxacillin in patients with impaired kidney function. Eur. J. Clin. Pharmacol. 22 (1982) 429-434
-
(1982)
Eur. J. Clin. Pharmacol.
, vol.22
, pp. 429-434
-
-
Thijssen, H.H.1
Wolters, J.2
-
51
-
-
0037379362
-
Bile salt transporters: molecular characterization, function, and regulation
-
Trauner M., and Boyer J.L. Bile salt transporters: molecular characterization, function, and regulation. Physiol. Rev. 83 (2003) 633-671
-
(2003)
Physiol. Rev.
, vol.83
, pp. 633-671
-
-
Trauner, M.1
Boyer, J.L.2
-
52
-
-
0035025946
-
Genetic disorders and molecular mechanisms in cholestatic liver disease-a clinical approach
-
Trauner M., Fickert P., and Zollner G. Genetic disorders and molecular mechanisms in cholestatic liver disease-a clinical approach. Semin. Gastrointest. Dis. 12 (2001) 66-88
-
(2001)
Semin. Gastrointest. Dis.
, vol.12
, pp. 66-88
-
-
Trauner, M.1
Fickert, P.2
Zollner, G.3
-
54
-
-
34547515667
-
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy
-
Van Mil S.W., Milona A., Dixon P.H., Mullenbach R., Geenes V.L., Chambers J., Shevchuk V., Moore G.E., Lammert F., Glantz A.G., Mattsson L.A., Whittaker J., Parker M.G., White R., and Williamson C. Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. Gastroenterology 133 (2007) 507-516
-
(2007)
Gastroenterology
, vol.133
, pp. 507-516
-
-
Van Mil, S.W.1
Milona, A.2
Dixon, P.H.3
Mullenbach, R.4
Geenes, V.L.5
Chambers, J.6
Shevchuk, V.7
Moore, G.E.8
Lammert, F.9
Glantz, A.G.10
Mattsson, L.A.11
Whittaker, J.12
Parker, M.G.13
White, R.14
Williamson, C.15
-
56
-
-
18844373318
-
Role of metabolism in drug-induced idiosyncratic hepatotoxicity
-
Walgren J.L., Mitchell M.D., and Thompson D.C. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Crit. Rev. Toxicol. 35 (2005) 325-361
-
(2005)
Crit. Rev. Toxicol.
, vol.35
, pp. 325-361
-
-
Walgren, J.L.1
Mitchell, M.D.2
Thompson, D.C.3
-
57
-
-
21144438395
-
Proteomic identification of potential susceptibility factors in drug-induced liver disease
-
Welch K.D., Wen B., Goodlett D.R., Yi E.C., Lee H., Reilly T.P., Nelson S.D., and Pohl L.R. Proteomic identification of potential susceptibility factors in drug-induced liver disease. Chem. Res. Toxicol. 18 (2005) 924-933
-
(2005)
Chem. Res. Toxicol.
, vol.18
, pp. 924-933
-
-
Welch, K.D.1
Wen, B.2
Goodlett, D.R.3
Yi, E.C.4
Lee, H.5
Reilly, T.P.6
Nelson, S.D.7
Pohl, L.R.8
-
58
-
-
0034785945
-
The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants
-
Zhang J., Kuehl P., Green E.D., Touchman J.W., Watkins P.B., Daly A., Hall S.D., Maurel P., Relling M., Brimer C., Yasuda K., Wrighton S.A., Hancock M., Kim R.B., Strom S., Thummel K., Russell C.G., Hudson Jr. J.R., Schuetz E.G., and Boguski M.S. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants. Pharmacogenetics 11 (2001) 555-572
-
(2001)
Pharmacogenetics
, vol.11
, pp. 555-572
-
-
Zhang, J.1
Kuehl, P.2
Green, E.D.3
Touchman, J.W.4
Watkins, P.B.5
Daly, A.6
Hall, S.D.7
Maurel, P.8
Relling, M.9
Brimer, C.10
Yasuda, K.11
Wrighton, S.A.12
Hancock, M.13
Kim, R.B.14
Strom, S.15
Thummel, K.16
Russell, C.G.17
Hudson Jr., J.R.18
Schuetz, E.G.19
Boguski, M.S.20
more..
-
59
-
-
0034424966
-
Drug-induced liver disease
-
Zimmerman H.J. Drug-induced liver disease. Clin. Liver Dis. 4 (2000) 73-96
-
(2000)
Clin. Liver Dis.
, vol.4
, pp. 73-96
-
-
Zimmerman, H.J.1
-
60
-
-
27444434833
-
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver
-
Zollner G., Wagner M., Fickert P., Geier A., Fuchsbichler A., Silbert D., Gumhold J., Zatloukal K., Kaser A., Tilg H., Denk H., and Trauner M. Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver. Am. J. Physiol. Gastrointest. Liver Physiol. 289 (2005) G798-G805
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.289
-
-
Zollner, G.1
Wagner, M.2
Fickert, P.3
Geier, A.4
Fuchsbichler, A.5
Silbert, D.6
Gumhold, J.7
Zatloukal, K.8
Kaser, A.9
Tilg, H.10
Denk, H.11
Trauner, M.12
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