Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia

Journal of Neuroscience

Volumn 24, Issue 41, 2004, Pages 9161-9173

  Guo, Wei ^a   Wei, Feng ^a   Zou, Shiping ^a   Robbins, Meredith T ^a   Sugiyo, Shinichi ^a   Ikeda, Tetsuya ^a   Tu, Jian Cheng ^b   Worley, Paul F ^b   Dubner, Ronald ^a   Ren, Ke ^a,c  

^a UNIVERSITY OF MARYLAND   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Department of Biomedical Sciences ^*  (United States)

Author keywords

CPCCOEt; Hyperalgesia; Inflammation; IP3; mGluR; MPEP; PKC; Src

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 2 AMINOETHOXYDIPHENYLBORANE; 4 AMINOPYRIDINE DERIVATIVE; 4 AMINOPYRROLIDINE 2,3 DICARBOXYLATE; 7 (HYDROXYIMINO)CYCLOPRA[B]CHROMEN 1A CARBOXYLATE ETHYL ESTER; CALCIUM; CELL PROTEIN; CGP 77675; DIHYDROXYPHENYLGLYCINE; FREUND ADJUVANT; GLUTAMATE RECEPTOR AGONIST; INOSITOL PHOSPHATE RECEPTOR AGONIST; INOSITOL PHOSPHATE RECEPTOR ANTAGONIST; IONOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 1 BLOCKING AGENT; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE C; PROTEIN SHANK; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE INHIBITOR; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; HYPERALGESIA; IMMUNOPRECIPITATION; INFLAMMATION; INHIBITION KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR DENSITY; REGULATORY MECHANISM; SPINAL CORD DORSAL HORN; SRC HOMOLOGY DOMAIN;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FREUND'S ADJUVANT; HINDLIMB; HYPERALGESIA; INFLAMMATION; MALE; PHOSPHORYLATION; POSTERIOR HORN CELLS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TYROSINE;

EID: 5644256896     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3422-04.2004     Document Type: Article

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