메뉴 건너뛰기




Volumn 12, Issue 11, 2008, Pages 1419-1430

Nm23-H 1/nucleoside diphosphate kinase as a key molecule in breast tumor angiogenesis

Author keywords

Angiogenesis; Breast cancer; Nm23 H1 NDP

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; ANTIINFECTIVE AGENT; BASIC FIBROBLAST GROWTH FACTOR; BEVACIZUMAB; DOCETAXEL; ENDOSTATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; GEFITINIB; NUCLEOSIDE DIPHOSPHATE KINASE A; PAZOPANIB; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHODIESTERASE I; PROTEIN BCL 2; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SERINE THREONINE KINASE RECEPTOR ASSOCIATED PROTEIN; SORAFENIB; SPLEEN EXONUCLEASE; SUNITINIB; THROMBOSPONDIN 1; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; VANDETANIB; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VATALANIB; ANTINEOPLASTIC AGENT; NUCLEOSIDE DIPHOSPHATE KINASE NM23;

EID: 56249133012     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.12.11.1419     Document Type: Review
Times cited : (13)

References (118)
  • 1
    • 0003964363 scopus 로고    scopus 로고
    • Available from:, Last accessed 26 September 2008
    • Cancer Fact & Figures 2008. Available from: http://www.cancer.org/ downloads/STT/2008CAFFfinalsecured.pdf [Last accessed 26 September 2008]
    • Cancer Fact & Figures 2008
  • 2
    • 43049117148 scopus 로고    scopus 로고
    • The molecular journey from ductal carcinoma in situ. to invasive breast cancer
    • Wiechmann L, Kuerer HM. The molecular journey from ductal carcinoma in situ. to invasive breast cancer. Cancer 2008;112(10):2130-42
    • (2008) Cancer , vol.112 , Issue.10 , pp. 2130-2142
    • Wiechmann, L.1    Kuerer, H.M.2
  • 3
    • 0034767957 scopus 로고    scopus 로고
    • Cancer burden in the year 2000. The global picture
    • Parkin DM, Bray FI, Devesa SS, et al. Cancer burden in the year 2000. The global picture. Eur J Cancer 2001;37(Suppl 8):S4-66
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL. 8
    • Parkin, D.M.1    Bray, F.I.2    Devesa, S.S.3
  • 4
    • 0028942008 scopus 로고
    • Breast cancer incidence in Asian migrants to the United States and their descendants
    • Stanford JL, Herrinton LJ, Schwartz SM, et al. Breast cancer incidence in Asian migrants to the United States and their descendants. Epidemiology 1995;6(2):181-3
    • (1995) Epidemiology , vol.6 , Issue.2 , pp. 181-183
    • Stanford, J.L.1    Herrinton, L.J.2    Schwartz, S.M.3
  • 5
    • 0027500144 scopus 로고
    • Breast cancer risk associated with proliferative breast disease and atypical hyperplasia
    • Dupont WD, Parl FF, Hartmann WH, et al. Breast cancer risk associated with proliferative breast disease and atypical hyperplasia. Cancer 1993;71(4):1258-65
    • (1993) Cancer , vol.71 , Issue.4 , pp. 1258-1265
    • Dupont, W.D.1    Parl, F.F.2    Hartmann, W.H.3
  • 6
    • 0023682278 scopus 로고
    • A prospective study of the development of breast cancer in 16,692 women with benign breast disease
    • Carter CL, Corle DK, Micozzi MS, et al. A prospective study of the development of breast cancer in 16,692 women with benign breast disease. Am J Epidemiol 1988;128(3):467-77
    • (1988) Am J Epidemiol , vol.128 , Issue.3 , pp. 467-477
    • Carter, C.L.1    Corle, D.K.2    Micozzi, M.S.3
  • 7
    • 0032694152 scopus 로고    scopus 로고
    • Genetic alterations in normal luminal and myoepithelial cells of the breast
    • Lakhani SR, Chaggar R, Davies S, et al. Genetic alterations in normal luminal and myoepithelial cells of the breast. J Pathol 1999;189(4):496-503
    • (1999) J Pathol , vol.189 , Issue.4 , pp. 496-503
    • Lakhani, S.R.1    Chaggar, R.2    Davies, S.3
  • 8
    • 0032490119 scopus 로고    scopus 로고
    • Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci
    • O'Connell P, Pekkel V, Fuqua SA, et al. Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci. J Natl Cancer Inst 1998;90(9):697-703
    • (1998) J Natl Cancer Inst , vol.90 , Issue.9 , pp. 697-703
    • O'Connell, P.1    Pekkel, V.2    Fuqua, S.A.3
  • 9
    • 4143087052 scopus 로고    scopus 로고
    • Patterns of chromosomal alterations in breast ductal carcinoma in situ
    • Hwang ES, DeVries S, Chew KL, et al. Patterns of chromosomal alterations in breast ductal carcinoma in situ. Clin Cancer Res 2004;10(15):5160-7
    • (2004) Clin Cancer Res , vol.10 , Issue.15 , pp. 5160-5167
    • Hwang, E.S.1    DeVries, S.2    Chew, K.L.3
  • 10
    • 0034121291 scopus 로고    scopus 로고
    • Genetic relation of lobular carcinoma in situ, ductal carcinoma in situ, and associated invasive carcinoma of the breast
    • Buerger H, Simon R, Schafer KL, et al. Genetic relation of lobular carcinoma in situ, ductal carcinoma in situ, and associated invasive carcinoma of the breast. Mol Pathol 2000;53(3):118-21
    • (2000) Mol Pathol , vol.53 , Issue.3 , pp. 118-121
    • Buerger, H.1    Simon, R.2    Schafer, K.L.3
  • 11
    • 0030785841 scopus 로고    scopus 로고
    • Amplification of CCND1 and expression of its protein product, cyclin D1, in ductal carcinoma in situ of the breast
    • Simpson JF, Quan DE, O'Malley F, et al. Amplification of CCND1 and expression of its protein product, cyclin D1, in ductal carcinoma in situ of the breast. Am J Pathol 1997;151(1):161-8
    • (1997) Am J Pathol , vol.151 , Issue.1 , pp. 161-168
    • Simpson, J.F.1    Quan, D.E.2    O'Malley, F.3
  • 12
    • 0034990662 scopus 로고    scopus 로고
    • Ductal invasive G2 and G3 carcinomas of the breast are the end stages of at least two different lines of genetic evolution
    • Buerger H, Mommers EC, Littmann R, et al. Ductal invasive G2 and G3 carcinomas of the breast are the end stages of at least two different lines of genetic evolution. J Pathol 2001;194(2):165-70
    • (2001) J Pathol , vol.194 , Issue.2 , pp. 165-170
    • Buerger, H.1    Mommers, E.C.2    Littmann, R.3
  • 13
    • 0035167343 scopus 로고    scopus 로고
    • Ductal epithelial proliferations of the breast: A biological continuum Comparative genomic hybridization and high-molecular-weight cytokeratin expression patterns
    • Boecker W, Buerger H, Schmitz K, et al. Ductal epithelial proliferations of the breast: a biological continuum Comparative genomic hybridization and high-molecular-weight cytokeratin expression patterns. J Pathol 2001;195(4):415-21
    • (2001) J Pathol , vol.195 , Issue.4 , pp. 415-421
    • Boecker, W.1    Buerger, H.2    Schmitz, K.3
  • 14
    • 34548462626 scopus 로고    scopus 로고
    • Mechanisms of disease: Angiogenesis and the management of breast cancer
    • Banerjee S, Dowsett M, Ashworth A, et al. Mechanisms of disease: angiogenesis and the management of breast cancer. Nat Clin Pract Oncol 2007;4(9):536-50
    • (2007) Nat Clin Pract Oncol , vol.4 , Issue.9 , pp. 536-550
    • Banerjee, S.1    Dowsett, M.2    Ashworth, A.3
  • 15
    • 0030512608 scopus 로고    scopus 로고
    • Hanahan D, Christofori G, Naik P, et al. Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models. Eur J Cancer 1996;32A14:2386-93
    • Hanahan D, Christofori G, Naik P, et al. Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models. Eur J Cancer 1996;32A14:2386-93
  • 16
    • 0030701960 scopus 로고    scopus 로고
    • Halting angiogenesis suppresses carcinoma cell invasion
    • Skobe M, Rockwell P, Goldstein N, et al. Halting angiogenesis suppresses carcinoma cell invasion. Nat Med 1997;3(11):1222-7
    • (1997) Nat Med , vol.3 , Issue.11 , pp. 1222-1227
    • Skobe, M.1    Rockwell, P.2    Goldstein, N.3
  • 17
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285(21):1182-6
    • (1971) N Engl J Med , vol.285 , Issue.21 , pp. 1182-1186
    • Folkman, J.1
  • 18
    • 33344468704 scopus 로고    scopus 로고
    • Pericytes and vascular stability
    • von Tell D, Armulik A, Betsholtz C, et al. Pericytes and vascular stability. Exp Cell Res 2006;312(5):623-9
    • (2006) Exp Cell Res , vol.312 , Issue.5 , pp. 623-629
    • von Tell, D.1    Armulik, A.2    Betsholtz, C.3
  • 19
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005;23(5):1011-27
    • (2005) J Clin Oncol , vol.23 , Issue.5 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 20
    • 0036831559 scopus 로고    scopus 로고
    • Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy
    • Rafii S, Lyden D, Benezra R, et al. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy Nat Rev Cancer 2002;2(11):826-35
    • (2002) Nat Rev Cancer , vol.2 , Issue.11 , pp. 826-835
    • Rafii, S.1    Lyden, D.2    Benezra, R.3
  • 21
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003;3(6):401-10
    • (2003) Nat Rev Cancer , vol.3 , Issue.6 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 22
    • 0028968307 scopus 로고
    • Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells
    • Mandriota SJ, Seghezzi G, Vassalli JD, et al. Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells. J Biol Chem 1995;270(17):9709-16
    • (1995) J Biol Chem , vol.270 , Issue.17 , pp. 9709-9716
    • Mandriota, S.J.1    Seghezzi, G.2    Vassalli, J.D.3
  • 23
    • 0026321129 scopus 로고
    • Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells
    • Pepper MS, Ferrara N, Orci L, et al. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 1991;181(2):902-6
    • (1991) Biochem Biophys Res Commun , vol.181 , Issue.2 , pp. 902-906
    • Pepper, M.S.1    Ferrara, N.2    Orci, L.3
  • 24
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
    • Gerber HP, McMurtrey A, Kowalski J, et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 1998;273(46):30336-43
    • (1998) J Biol Chem , vol.273 , Issue.46 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3
  • 25
    • 0036006171 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF), a survival factor for tumour cells: Implications for anti-angiogenic therapy
    • Harmey JH, Bouchier-Hayes D. Vascular endothelial growth factor (VEGF), a survival factor for tumour cells: implications for anti-angiogenic therapy. Bioessays 2002;24(3):280-3
    • (2002) Bioessays , vol.24 , Issue.3 , pp. 280-283
    • Harmey, J.H.1    Bouchier-Hayes, D.2
  • 26
    • 0037007037 scopus 로고    scopus 로고
    • A role for survivin in chemoresistance of endothelial cells mediated by VEGF
    • Tran J, Master Z, Yu JL, et al. A role for survivin in chemoresistance of endothelial cells mediated by VEGF. Proc Natl Acad Sci USA 2002;99(7):4349-54
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.7 , pp. 4349-4354
    • Tran, J.1    Master, Z.2    Yu, J.L.3
  • 27
    • 0033708398 scopus 로고    scopus 로고
    • Complete inhibition of rhabdomyosarcoma xenograft growth and neovascularization requires blockade of both tumor and host vascular endothelial growth factor
    • Gerber HP, Kowalski J, Sherman D, et al. Complete inhibition of rhabdomyosarcoma xenograft growth and neovascularization requires blockade of both tumor and host vascular endothelial growth factor. Cancer Res 2000;60(22):6253-8
    • (2000) Cancer Res , vol.60 , Issue.22 , pp. 6253-6258
    • Gerber, H.P.1    Kowalski, J.2    Sherman, D.3
  • 28
    • 0034650744 scopus 로고    scopus 로고
    • Oncogenes and tumor angiogenesis: Differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts
    • Rak J, Mitsuhashi Y, Sheehan C, et al. Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts. Cancer Res 2000;60(2):490-8
    • (2000) Cancer Res , vol.60 , Issue.2 , pp. 490-498
    • Rak, J.1    Mitsuhashi, Y.2    Sheehan, C.3
  • 29
    • 0028834638 scopus 로고
    • Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells
    • Grugel S, Finkenzeller G, Weindel K, et al. Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells. J Biol Chem 1995;270(43):25915-9
    • (1995) J Biol Chem , vol.270 , Issue.43 , pp. 25915-25919
    • Grugel, S.1    Finkenzeller, G.2    Weindel, K.3
  • 30
    • 0030869787 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element
    • Mazure NM, Chen EY, Laderoute KR, et al. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 1997;90(9):3322-31
    • (1997) Blood , vol.90 , Issue.9 , pp. 3322-3331
    • Mazure, N.M.1    Chen, E.Y.2    Laderoute, K.R.3
  • 31
    • 0030893967 scopus 로고    scopus 로고
    • Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity
    • Volpert OV, Dameron KM, Bouck N, et al. Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity. Oncogene 1997;14(12):1495-502
    • (1997) Oncogene , vol.14 , Issue.12 , pp. 1495-1502
    • Volpert, O.V.1    Dameron, K.M.2    Bouck, N.3
  • 32
    • 8544249876 scopus 로고    scopus 로고
    • Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia
    • Enholm B, Paavonen K, Ristimaki A, et al. Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia. Oncogene 1997;14(20):2475-83
    • (1997) Oncogene , vol.14 , Issue.20 , pp. 2475-2483
    • Enholm, B.1    Paavonen, K.2    Ristimaki, A.3
  • 33
    • 0027739807 scopus 로고
    • Biological activity of a K-ras mutant that contains the 12R/59T/116Y mutations
    • Ogiso Y, Hwang YW, Shih TY, et al. Biological activity of a K-ras mutant that contains the 12R/59T/116Y mutations. Cancer Lett 1993;75(1):19-26
    • (1993) Cancer Lett , vol.75 , Issue.1 , pp. 19-26
    • Ogiso, Y.1    Hwang, Y.W.2    Shih, T.Y.3
  • 34
    • 0030447757 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels
    • Larcher F, Robles AI, Duran H, et al. Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels. Cancer Res 1996;56(23):5391-6
    • (1996) Cancer Res , vol.56 , Issue.23 , pp. 5391-5396
    • Larcher, F.1    Robles, A.I.2    Duran, H.3
  • 35
    • 33751074452 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 in human breast and prostate cancer
    • Kimbro KS, Simons JW. Hypoxia-inducible factor-1 in human breast and prostate cancer. Endocr Relat Cancer 2006;13(3):739-49
    • (2006) Endocr Relat Cancer , vol.13 , Issue.3 , pp. 739-749
    • Kimbro, K.S.1    Simons, J.W.2
  • 36
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235(4785):177-82
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 37
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005;353(16):1659-72
    • (2005) N Engl J Med , vol.353 , Issue.16 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 38
    • 33750584030 scopus 로고    scopus 로고
    • HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: Implications for HER2-targeted antibody therapy
    • Wen XF, Yang G, Mao W, et al. HER2 signaling modulates the equilibrium between pro- and antiangiogenic factors via distinct pathways: implications for HER2-targeted antibody therapy. Oncogene 2006;25(52):6986-96
    • (2006) Oncogene , vol.25 , Issue.52 , pp. 6986-6996
    • Wen, X.F.1    Yang, G.2    Mao, W.3
  • 39
    • 33644529055 scopus 로고    scopus 로고
    • ErbB2 increases vascular endothelial grown factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells
    • Klos KS, Wyszomierski SL, Sun M, et al. ErbB2 increases vascular endothelial grown factor protein synthesis via activation of mammalian target of rapamycin/p70S6K leading to increased angiogenesis and spontaneous metastasis of human breast cancer cells. Cancer Res 2006;66(4):2028-37
    • (2006) Cancer Res , vol.66 , Issue.4 , pp. 2028-2037
    • Klos, K.S.1    Wyszomierski, S.L.2    Sun, M.3
  • 40
    • 0034896362 scopus 로고    scopus 로고
    • Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
    • Ciardiello F, Caputo R, Bianco R, et al. Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor. Clin Cancer Res 2001;7(5):1459-65
    • (2001) Clin Cancer Res , vol.7 , Issue.5 , pp. 1459-1465
    • Ciardiello, F.1    Caputo, R.2    Bianco, R.3
  • 41
    • 20444431504 scopus 로고    scopus 로고
    • The antitumor and antiangiogenic activity of vascular endothelial growth factor receptor inhibition is potentiated by ErbB1 blockade
    • Sini P, Wyder L, Schnell C, et al. The antitumor and antiangiogenic activity of vascular endothelial growth factor receptor inhibition is potentiated by ErbB1 blockade. Clin Cancer Res 2005;11(12):4521-32
    • (2005) Clin Cancer Res , vol.11 , Issue.12 , pp. 4521-4532
    • Sini, P.1    Wyder, L.2    Schnell, C.3
  • 42
    • 0037149539 scopus 로고    scopus 로고
    • Tumour biology: Herceptin acts as an anti-angiogenic cocktail
    • Izumi Y, Xu L, di Tomaso E, et al. Tumour biology: herceptin acts as an anti-angiogenic cocktail. Nature 2002;416(6878):279-80
    • (2002) Nature , vol.416 , Issue.6878 , pp. 279-280
    • Izumi, Y.1    Xu, L.2    di Tomaso, E.3
  • 43
    • 0035870297 scopus 로고    scopus 로고
    • The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors
    • Sweeney CJ, Miller KD, Sissons SE, et al. The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 2001;61(8):3369-72
    • (2001) Cancer Res , vol.61 , Issue.8 , pp. 3369-3372
    • Sweeney, C.J.1    Miller, K.D.2    Sissons, S.E.3
  • 44
    • 0034032882 scopus 로고    scopus 로고
    • Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
    • Browder T, Butterfield CE, Kraling BM, et al. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 2000;60(7):1878-86
    • (2000) Cancer Res , vol.60 , Issue.7 , pp. 1878-1886
    • Browder, T.1    Butterfield, C.E.2    Kraling, B.M.3
  • 45
    • 0034087691 scopus 로고    scopus 로고
    • Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity
    • Klement G, Baruchel S, Rak J, et al. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J Clin Invest 2000;105(8):R15-24
    • (2000) J Clin Invest , vol.105 , Issue.8
    • Klement, G.1    Baruchel, S.2    Rak, J.3
  • 46
    • 0037093209 scopus 로고    scopus 로고
    • Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water
    • Man S, Bocci G, Francis G, et al. Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water. Cancer Res 2002;62(10):2731-5
    • (2002) Cancer Res , vol.62 , Issue.10 , pp. 2731-2735
    • Man, S.1    Bocci, G.2    Francis, G.3
  • 47
    • 0036897097 scopus 로고    scopus 로고
    • Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs
    • Bocci G, Nicolaou KC, Kerbel RS, et al. Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Res 2002;62(23):6938-43
    • (2002) Cancer Res , vol.62 , Issue.23 , pp. 6938-6943
    • Bocci, G.1    Nicolaou, K.C.2    Kerbel, R.S.3
  • 48
    • 1642368865 scopus 로고    scopus 로고
    • Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression
    • Hamano Y, Sugimoto H, Soubasakos MA, et al. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res 2004;64(5):1570-4
    • (2004) Cancer Res , vol.64 , Issue.5 , pp. 1570-1574
    • Hamano, Y.1    Sugimoto, H.2    Soubasakos, M.A.3
  • 49
    • 0242331613 scopus 로고    scopus 로고
    • Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
    • Bocci G, Francis G, Man S, et al. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci USA 2003;100(22):12917-22
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.22 , pp. 12917-12922
    • Bocci, G.1    Francis, G.2    Man, S.3
  • 50
    • 20444490772 scopus 로고    scopus 로고
    • Targeting angiogenesis in cancer: Clinical development of bevacizumab
    • Kerr DJ. Targeting angiogenesis in cancer: clinical development of bevacizumab. Nat Cljn Pract Oncol 2004;1(1):39-43
    • (2004) Nat Cljn Pract Oncol , vol.1 , Issue.1 , pp. 39-43
    • Kerr, D.J.1
  • 51
    • 0028170817 scopus 로고
    • Receptor protein-tyrosine kinases and their signal transduction pathways
    • van der Geer P, Hunter T, Lindberg RA, et al. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol 1994;10:251-337
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 251-337
    • van der Geer, P.1    Hunter, T.2    Lindberg, R.A.3
  • 52
    • 0029021904 scopus 로고
    • Endothelial receptor tyrosine kinases involved in angiogenesis
    • Mustonen T, Alitalo K. Endothelial receptor tyrosine kinases involved in angiogenesis. J Cell Biol 1995;129(4):895-8
    • (1995) J Cell Biol , vol.129 , Issue.4 , pp. 895-898
    • Mustonen, T.1    Alitalo, K.2
  • 53
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005;307(5706):58-62
    • (2005) Science , vol.307 , Issue.5706 , pp. 58-62
    • Jain, R.K.1
  • 55
    • 0036289066 scopus 로고    scopus 로고
    • 1 gene transfer on in vivo growth of human breast cancer cells
    • 1 gene transfer on in vivo growth of human breast cancer cells. Gene Ther 2002; 9(13):867-78
    • (2002) Gene Ther , vol.9 , Issue.13 , pp. 867-878
    • Indraccolo, S.1    Gola, E.2    Rosato, A.3
  • 56
    • 28444476260 scopus 로고    scopus 로고
    • Angiogenic inhibitors: A new therapeutic strategy in oncology
    • Gasparini G, Longo R, Toi M, et al. Angiogenic inhibitors: a new therapeutic strategy in oncology. Nat Clin Pract Oncol 2005;2(11):562-77
    • (2005) Nat Clin Pract Oncol , vol.2 , Issue.11 , pp. 562-577
    • Gasparini, G.1    Longo, R.2    Toi, M.3
  • 57
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100(1):57-70
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 58
    • 0037264812 scopus 로고    scopus 로고
    • Metastasis suppressors alter the signal transduction of cancer cells
    • Steeg PS. Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 2003;3(1):55-63
    • (2003) Nat Rev Cancer , vol.3 , Issue.1 , pp. 55-63
    • Steeg, P.S.1
  • 59
    • 0035999133 scopus 로고    scopus 로고
    • Critical determinants of metastasis
    • Fidler IJ. Critical determinants of metastasis. Semin Cancer Biol 2002;12(2):89-96
    • (2002) Semin Cancer Biol , vol.12 , Issue.2 , pp. 89-96
    • Fidler, I.J.1
  • 60
    • 0023937268 scopus 로고
    • Evidence for a novel gene associated with low tumor metastatic potential
    • Steeg PS, Bevilacqua G, Kopper L, et al. Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst 1988;80(3):200-4
    • (1988) J Natl Cancer Inst , vol.80 , Issue.3 , pp. 200-204
    • Steeg, P.S.1    Bevilacqua, G.2    Kopper, L.3
  • 61
    • 0025287814 scopus 로고
    • Functional cloning of a nucleoside diphosphate kinase from Dictyostelium discoideum
    • Lacombe ML, Wallet V, Troll H, et al. Functional cloning of a nucleoside diphosphate kinase from Dictyostelium discoideum. J Biol Chem 1990;265(17):10012-8
    • (1990) J Biol Chem , vol.265 , Issue.17 , pp. 10012-10018
    • Lacombe, M.L.1    Wallet, V.2    Troll, H.3
  • 62
    • 0025291302 scopus 로고
    • Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development
    • Wallet V, Mutzel R, Troll H, et al. Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development. J Natl Cancer Inst 1990;82(14):1199-202
    • (1990) J Natl Cancer Inst , vol.82 , Issue.14 , pp. 1199-1202
    • Wallet, V.1    Mutzel, R.2    Troll, H.3
  • 63
    • 0033804737 scopus 로고    scopus 로고
    • The human Nm23/nucleoside diphosphate kinases
    • Lacombe ML, Milon L, Munier A, et al. The human Nm23/nucleoside diphosphate kinases. J Bioenerg Biomembr 2000;32(3):247-58
    • (2000) J Bioenerg Biomembr , vol.32 , Issue.3 , pp. 247-258
    • Lacombe, M.L.1    Milon, L.2    Munier, A.3
  • 64
    • 0017873959 scopus 로고
    • Nucleoside diphosphokinase from human erythrocytes
    • Agarwal RP, Robison B, Parks RE Jr, et al. Nucleoside diphosphokinase from human erythrocytes. Methods Enzymol 1978;51:376-386
    • (1978) Methods Enzymol , vol.51 , pp. 376-386
    • Agarwal, R.P.1    Robison, B.2    Parks Jr, R.E.3
  • 65
    • 0029170669 scopus 로고
    • Nm23/nucleoside diphosphate kinase: Toward a structural and biochemical understanding of its biological functions
    • de la Rosa A, Williams RL, Steeg PS, et al. Nm23/nucleoside diphosphate kinase: toward a structural and biochemical understanding of its biological functions. Bioessays 1995;17(1):53-62
    • (1995) Bioessays , vol.17 , Issue.1 , pp. 53-62
    • de la Rosa, A.1    Williams, R.L.2    Steeg, P.S.3
  • 66
    • 0025914104 scopus 로고
    • Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme
    • Gilles AM, Presecan E, Vonica A, et al. Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme. J Biol Chem 1991;266(14):8784-9
    • (1991) J Biol Chem , vol.266 , Issue.14 , pp. 8784-8789
    • Gilles, A.M.1    Presecan, E.2    Vonica, A.3
  • 67
    • 0014473526 scopus 로고
    • Kinetic studies of yeast nucleoside diphosphate kinase
    • Garces E, Cleland WW. Kinetic studies of yeast nucleoside diphosphate kinase. Biochem 1969;8(2):633-40
    • (1969) Biochem , vol.8 , Issue.2 , pp. 633-640
    • Garces, E.1    Cleland, W.W.2
  • 68
    • 20444447134 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer
    • Palmieri D, Halverson DO, Ouatas T, et al. Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer. J Natl Cancer Inst 2005;97(9):632-42
    • (2005) J Natl Cancer Inst , vol.97 , Issue.9 , pp. 632-642
    • Palmieri, D.1    Halverson, D.O.2    Ouatas, T.3
  • 69
    • 0141568002 scopus 로고    scopus 로고
    • Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: New uses for old compounds
    • Ouatas T, Halverson D, Steeg PS, et al. Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: new uses for old compounds. Clin Cancer Res 2003;9(10 Pt 1):3763-72
    • (2003) Clin Cancer Res , vol.9 , Issue.10 PART 1 , pp. 3763-3772
    • Ouatas, T.1    Halverson, D.2    Steeg, P.S.3
  • 70
    • 0031041899 scopus 로고    scopus 로고
    • Site-directed mutation of Nm23-H1. Mutations lacking motility suppressive capacity upon transfection are deficient in histidine dependent protein phosphotransferase pathways in vitro
    • Freije JM, Blay P, MacDonald NJ, et al. Site-directed mutation of Nm23-H1. Mutations lacking motility suppressive capacity upon transfection are deficient in histidine dependent protein phosphotransferase pathways in vitro. J Biol Chem 1997;272(9):5525-32
    • (1997) J Biol Chem , vol.272 , Issue.9 , pp. 5525-5532
    • Freije, J.M.1    Blay, P.2    MacDonald, N.J.3
  • 71
    • 0022450555 scopus 로고
    • Primary rat embryo cells transformed by one or two oncogenes show different metastatic potentials
    • Pozzatti R, Muschel R, Williams J, et al. Primary rat embryo cells transformed by one or two oncogenes show different metastatic potentials. Science 1986;232(4747):223-7
    • (1986) Science , vol.232 , Issue.4747 , pp. 223-227
    • Pozzatti, R.1    Muschel, R.2    Williams, J.3
  • 72
    • 16844376315 scopus 로고    scopus 로고
    • Oncogenic Ras in tumour progression and metastasis
    • Giehl K. Oncogenic Ras in tumour progression and metastasis. Biol Chem 2005;386(3):193-205
    • (2005) Biol Chem , vol.386 , Issue.3 , pp. 193-205
    • Giehl, K.1
  • 74
    • 13444278768 scopus 로고    scopus 로고
    • Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells
    • Salerno M, Palmieri D, Bouadis A, et al. Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells. Mol Cell Biol 2005;25(4):1379-88
    • (2005) Mol Cell Biol , vol.25 , Issue.4 , pp. 1379-1388
    • Salerno, M.1    Palmieri, D.2    Bouadis, A.3
  • 75
    • 0033805226 scopus 로고    scopus 로고
    • NM23/nucleoside diphosphate kinase and signal transduction
    • Otero AS. NM23/nucleoside diphosphate kinase and signal transduction. J Bioenerg Biomembr 2000;32(3):269-75
    • (2000) J Bioenerg Biomembr , vol.32 , Issue.3 , pp. 269-275
    • Otero, A.S.1
  • 76
    • 0025612249 scopus 로고
    • A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase
    • Biggs J, Hersperger E, Steeg PS, et al. A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase. Cell 1990;63(5):933-40
    • (1990) Cell , vol.63 , Issue.5 , pp. 933-940
    • Biggs, J.1    Hersperger, E.2    Steeg, P.S.3
  • 77
    • 0033080406 scopus 로고    scopus 로고
    • Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: Specific nuclear localization of the B subunit
    • Pinon VP, Millot G, Munier A et al. Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit. Exp Cell Res 1999;246(2):355-67
    • (1999) Exp Cell Res , vol.246 , Issue.2 , pp. 355-367
    • Pinon, V.P.1    Millot, G.2    Munier, A.3
  • 78
    • 0031850378 scopus 로고    scopus 로고
    • Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts
    • Eckes B, Dogic D, Colucci-Guyon E, et al. Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts. J Cell Sci 1998;111(Pt 13):1897-1907
    • (1998) J Cell Sci , vol.111 , Issue.PART 13 , pp. 1897-1907
    • Eckes, B.1    Dogic, D.2    Colucci-Guyon, E.3
  • 79
    • 0033373537 scopus 로고    scopus 로고
    • Vimentin contributes to human mammary epithelial cell migration
    • Gilles C, Polette M, Zahm JM, et al. Vimentin contributes to human mammary epithelial cell migration. J Cell Sci 1999;112(Pt 24):4615-25
    • (1999) J Cell Sci , vol.112 , Issue.PART 24 , pp. 4615-4625
    • Gilles, C.1    Polette, M.2    Zahm, J.M.3
  • 80
    • 0037532411 scopus 로고    scopus 로고
    • Basic and translational advances in cancer metastasis: Nm23
    • Ouatas T, Salerno M, Palmieri D, et al. Basic and translational advances in cancer metastasis: Nm23. J Bioenerg Biomembr 2003;35(1):73-79
    • (2003) J Bioenerg Biomembr , vol.35 , Issue.1 , pp. 73-79
    • Ouatas, T.1    Salerno, M.2    Palmieri, D.3
  • 81
    • 22144481597 scopus 로고    scopus 로고
    • Expression of c-myc, erbB-2, p53 and nm23-H1 gene product in benign and malignant breast lesions: Coexpression and correlation with clinicopathologic parameters
    • Sirotkovic-Skerlev M, Krizanac S, Kapitanovic S, et al. Expression of c-myc, erbB-2, p53 and nm23-H1 gene product in benign and malignant breast lesions: coexpression and correlation with clinicopathologic parameters. Exp Mol Pathol 2005;79(1):42-50
    • (2005) Exp Mol Pathol , vol.79 , Issue.1 , pp. 42-50
    • Sirotkovic-Skerlev, M.1    Krizanac, S.2    Kapitanovic, S.3
  • 82
    • 0032535654 scopus 로고    scopus 로고
    • Expression of nm23 in gastric carcinoma: Association with tumor progression and poor prognosis
    • Muller W, Schneiders A, Hommel G, et al. Expression of nm23 in gastric carcinoma: association with tumor progression and poor prognosis. Cancer 1998;83(12):2481-7
    • (1998) Cancer , vol.83 , Issue.12 , pp. 2481-2487
    • Muller, W.1    Schneiders, A.2    Hommel, G.3
  • 83
    • 0030432708 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi
    • Lee CS, Pirdas A, Lee MW, et al. Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi. Pathology 1996;28(3):220-224
    • (1996) Pathology , vol.28 , Issue.3 , pp. 220-224
    • Lee, C.S.1    Pirdas, A.2    Lee, M.W.3
  • 84
    • 10044228613 scopus 로고    scopus 로고
    • nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma
    • Kapitanovic S, Cacev T, Berkovic M, et al. nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma. J Clin Pathol 2004;57(12):1312-8
    • (2004) J Clin Pathol , vol.57 , Issue.12 , pp. 1312-1318
    • Kapitanovic, S.1    Cacev, T.2    Berkovic, M.3
  • 85
    • 0027169499 scopus 로고
    • High levels of Nm23 gene expression in advanced stage of thyroid carcinomas
    • Zou M, Shi Y, al-Sedairy S, et al. High levels of Nm23 gene expression in advanced stage of thyroid carcinomas. Br J Cancer 1993;68(2):385-8
    • (1993) Br J Cancer , vol.68 , Issue.2 , pp. 385-388
    • Zou, M.1    Shi, Y.2    al-Sedairy, S.3
  • 86
    • 20044396717 scopus 로고    scopus 로고
    • Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors
    • Ferenc T, Lewinski A, Lange D, et al. Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors. Pol J Pathol 2004;55(4):149-53
    • (2004) Pol J Pathol , vol.55 , Issue.4 , pp. 149-153
    • Ferenc, T.1    Lewinski, A.2    Lange, D.3
  • 87
    • 0027465480 scopus 로고
    • Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas
    • Leone A, Seeger RC, Hong CM, et al. Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas. Oncogene 1993;8(4):855-65
    • (1993) Oncogene , vol.8 , Issue.4 , pp. 855-865
    • Leone, A.1    Seeger, R.C.2    Hong, C.M.3
  • 88
    • 0033938552 scopus 로고    scopus 로고
    • Comparison of histological changes and hanges in nm23 and c-MET expression between primary and metastatic sites in osteosarcoma: A clinicopathologic and immunohistochemical study
    • Oda Y, Naka T, Takeshita M, et al. Comparison of histological changes and hanges in nm23 and c-MET expression between primary and metastatic sites in osteosarcoma: a clinicopathologic and immunohistochemical study. Hum Pathol 2000;31(6):709-16
    • (2000) Hum Pathol , vol.31 , Issue.6 , pp. 709-716
    • Oda, Y.1    Naka, T.2    Takeshita, M.3
  • 89
    • 0036029850 scopus 로고    scopus 로고
    • Immunoexpression of nm23 in advanced esophageal squamous cell carcinoma
    • Szumilo J, Skomra D, Chibowski D, et al. Immunoexpression of nm23 in advanced esophageal squamous cell carcinoma. Folia Histochem Cytobiol 2002;40(4):377-80
    • (2002) Folia Histochem Cytobiol , vol.40 , Issue.4 , pp. 377-380
    • Szumilo, J.1    Skomra, D.2    Chibowski, D.3
  • 90
    • 0037428893 scopus 로고    scopus 로고
    • Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer
    • Steeg PS, Palmieri D, Ouatas T, et al. Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancer. Cancer Lett 2003;190(1):1-12
    • (2003) Cancer Lett , vol.190 , Issue.1 , pp. 1-12
    • Steeg, P.S.1    Palmieri, D.2    Ouatas, T.3
  • 92
    • 0037199995 scopus 로고    scopus 로고
    • Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway
    • Hartsough MT, Morrison DK, Salerno M, et al. Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway. J Biol Chem 2002;277(35):32389-99
    • (2002) J Biol Chem , vol.277 , Issue.35 , pp. 32389-32399
    • Hartsough, M.T.1    Morrison, D.K.2    Salerno, M.3
  • 93
    • 33745501366 scopus 로고    scopus 로고
    • The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death
    • Chowdhury D, Beresford PJ, Zhu P, et al. The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death. Mol Cell 2006;23(1):133-42
    • (2006) Mol Cell , vol.23 , Issue.1 , pp. 133-142
    • Chowdhury, D.1    Beresford, P.J.2    Zhu, P.3
  • 94
    • 0037423932 scopus 로고    scopus 로고
    • Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
    • Fan Z, Beresford PJ, Oh DY, et al. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell 2003;112(5):659-72
    • (2003) Cell , vol.112 , Issue.5 , pp. 659-672
    • Fan, Z.1    Beresford, P.J.2    Oh, D.Y.3
  • 95
    • 0141629512 scopus 로고    scopus 로고
    • Nuclear war: The granzyme A-bomb
    • Lieberman J, Fan Z. Nuclear war: the granzyme A-bomb. Curr Opin Immunol 2003;15(5):553-9
    • (2003) Curr Opin Immunol , vol.15 , Issue.5 , pp. 553-559
    • Lieberman, J.1    Fan, Z.2
  • 96
    • 0031953260 scopus 로고    scopus 로고
    • The mutation rate and cancer
    • Jackson AL, Loeb LA. The mutation rate and cancer. Genetics 1998;148(4):1483-90
    • (1998) Genetics , vol.148 , Issue.4 , pp. 1483-1490
    • Jackson, A.L.1    Loeb, L.A.2
  • 97
    • 0035836637 scopus 로고    scopus 로고
    • Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1
    • Otsuki Y, Tanaka M, Yoshii S, et al. Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1. Proc Natl Acad Sci USA 2001;98(8):4385-90
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.8 , pp. 4385-4390
    • Otsuki, Y.1    Tanaka, M.2    Yoshii, S.3
  • 98
    • 44449149146 scopus 로고    scopus 로고
    • JNK as a positive regulator of angiogenic potential in endothelial cells
    • Uchida C, Gee E, Ispanovic E, et al. JNK as a positive regulator of angiogenic potential in endothelial cells. Cell Biol Int 2008;32(7):769-776
    • (2008) Cell Biol Int , vol.32 , Issue.7 , pp. 769-776
    • Uchida, C.1    Gee, E.2    Ispanovic, E.3
  • 99
    • 13644259000 scopus 로고    scopus 로고
    • MAPK signaling regulates endothelial cell assembly into networks and expression of MT1-MMP and MMP-2
    • Boyd PJ, Doyle J, Gee E, et al. MAPK signaling regulates endothelial cell assembly into networks and expression of MT1-MMP and MMP-2. Am J Physiol Cell Physiol 2005;288(3):C659-68
    • (2005) Am J Physiol Cell Physiol , vol.288 , Issue.3
    • Boyd, P.J.1    Doyle, J.2    Gee, E.3
  • 100
    • 33749315900 scopus 로고    scopus 로고
    • JNK and PI3K differentially regulate MMP-2 and MT1-MMP mRNA and protein in response to actin cytoskeleton reorganization in endothelial cells
    • Ispanovic E, Haas TL. JNK and PI3K differentially regulate MMP-2 and MT1-MMP mRNA and protein in response to actin cytoskeleton reorganization in endothelial cells. Am J Physiol Cell Physiol 2006;291(4):C579-88
    • (2006) Am J Physiol Cell Physiol , vol.291 , Issue.4
    • Ispanovic, E.1    Haas, T.L.2
  • 101
    • 36148931807 scopus 로고    scopus 로고
    • Purinergic regulation of angiogenesis by human breast carcinoma-secreted nucleoside diphosphate kinase
    • Rumjahn SM, Javed MA, Wong N, et al. Purinergic regulation of angiogenesis by human breast carcinoma-secreted nucleoside diphosphate kinase. Br J Cancer 2007;97(1):1372-80
    • (2007) Br J Cancer , vol.97 , Issue.1 , pp. 1372-1380
    • Rumjahn, S.M.1    Javed, M.A.2    Wong, N.3
  • 102
    • 0035810936 scopus 로고    scopus 로고
    • Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin
    • Moser TL, Kenan DJ, Ashley TA, et al. Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proc Natl Acad Sci USA 2001;98(12):6656-61
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.12 , pp. 6656-6661
    • Moser, T.L.1    Kenan, D.J.2    Ashley, T.A.3
  • 103
    • 0035099271 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: A molecular link to cancer metastasis
    • Subramanian C, Cotter MA, 2nd, Robertson ES, et al. Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis. Nat Med 2001;7(3):350-5
    • (2001) Nat Med , vol.7 , Issue.3 , pp. 350-355
    • Subramanian, C.1    Cotter 2nd, M.A.2    Robertson, E.S.3
  • 104
    • 33745928756 scopus 로고    scopus 로고
    • Expression of alpha V integrin is modulated by Epstein-Barr virus nuclear antigen 3C and the metastasis suppressor Nm23-H1 through interaction with the GATA-1 and Sp1 transcription factors
    • Choudhuri T, Verma SC, Lan K, et al. Expression of alpha V integrin is modulated by Epstein-Barr virus nuclear antigen 3C and the metastasis suppressor Nm23-H1 through interaction with the GATA-1 and Sp1 transcription factors. Virology 2006;351(1):58-72
    • (2006) Virology , vol.351 , Issue.1 , pp. 58-72
    • Choudhuri, T.1    Verma, S.C.2    Lan, K.3
  • 105
    • 2942511783 scopus 로고    scopus 로고
    • An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1
    • Elkin M, Orgel A, Kleinman HK, et al. An angiogenic switch in breast cancer involves estrogen and soluble vascular endothelial growth factor receptor 1. J Natl Cancer Inst 2004;96(11):875-8
    • (2004) J Natl Cancer Inst , vol.96 , Issue.11 , pp. 875-878
    • Elkin, M.1    Orgel, A.2    Kleinman, H.K.3
  • 106
    • 0028281416 scopus 로고
    • Tumor angiogenesis in node-negative breast carcinomas - relationship with epidermal growth factor receptor, estrogen receptor, and survival
    • Fox SB, Leek RD, Smith K, et al. Tumor angiogenesis in node-negative breast carcinomas - relationship with epidermal growth factor receptor, estrogen receptor, and survival. Breast Cancer Res Treat 1994;29(1):109-16
    • (1994) Breast Cancer Res Treat , vol.29 , Issue.1 , pp. 109-116
    • Fox, S.B.1    Leek, R.D.2    Smith, K.3
  • 107
    • 35948976905 scopus 로고    scopus 로고
    • Interaction of the tumor metastasis suppressor nonmerastatic protein 23 homologue H1 and estrogen receptor α alters estrogen-responsive gene expression
    • Curtis CD, Likhite VS, McLeod IX, et al. Interaction of the tumor metastasis suppressor nonmerastatic protein 23 homologue H1 and estrogen receptor α alters estrogen-responsive gene expression. Cancer Res 2007;67(21):10600-7
    • (2007) Cancer Res , vol.67 , Issue.21 , pp. 10600-10607
    • Curtis, C.D.1    Likhite, V.S.2    McLeod, I.X.3
  • 108
    • 36849054976 scopus 로고    scopus 로고
    • NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function
    • Jung H, Seong HA, Ha H, et al. NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function. J Biol Chem 2007;282(48):35293-307
    • (2007) J Biol Chem , vol.282 , Issue.48 , pp. 35293-35307
    • Jung, H.1    Seong, H.A.2    Ha, H.3
  • 109
    • 0842333147 scopus 로고    scopus 로고
    • Prognostic significance of transforming growth factor β receptor II in estrogen receptor-negative breast cancer patients
    • Buck MB, Fritz P, Dippon J, et al. Prognostic significance of transforming growth factor β receptor II in estrogen receptor-negative breast cancer patients. Clin Cancer Res 2004; 10(2):491-8
    • (2004) Clin Cancer Res , vol.10 , Issue.2 , pp. 491-498
    • Buck, M.B.1    Fritz, P.2    Dippon, J.3
  • 110
    • 0037474223 scopus 로고    scopus 로고
    • Autocrine transforming growth factor-β signaling mediates Smad-independent motility in human cancer cells
    • Dumont N, Bakin AV, Arteaga CL, et al. Autocrine transforming growth factor-β signaling mediates Smad-independent motility in human cancer cells. J Biol Chem 2003;278(5):3275-85
    • (2003) J Biol Chem , vol.278 , Issue.5 , pp. 3275-3285
    • Dumont, N.1    Bakin, A.V.2    Arteaga, C.L.3
  • 111
    • 0033592951 scopus 로고    scopus 로고
    • Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation
    • Zhu J, Tseng YH, Kantor JD, et al. Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation. Proc Natl Acad Sci USA 1999;96(26):14911-8
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.26 , pp. 14911-14918
    • Zhu, J.1    Tseng, Y.H.2    Kantor, J.D.3
  • 112
    • 33746956118 scopus 로고    scopus 로고
    • Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK
    • Kim SH, Kim J. Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK. Biochim Biophys Acta 2006;1763(8):823-32
    • (2006) Biochim Biophys Acta , vol.1763 , Issue.8 , pp. 823-832
    • Kim, S.H.1    Kim, J.2
  • 113
    • 41149180629 scopus 로고    scopus 로고
    • Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility
    • Garzia L, D'Angelo A, Amoresano A, et al. Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility. Oncogene 2008;27(13):1853-64
    • (2008) Oncogene , vol.27 , Issue.13 , pp. 1853-1864
    • Garzia, L.1    D'Angelo, A.2    Amoresano, A.3
  • 114
    • 0037115829 scopus 로고    scopus 로고
    • The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1
    • Du J, Hannon GJ. The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1. Nucleic Acids Res 2002;30(24):5465-75
    • (2002) Nucleic Acids Res , vol.30 , Issue.24 , pp. 5465-5475
    • Du, J.1    Hannon, G.J.2
  • 115
    • 13744251264 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migration
    • Murakami M, Lan K, Subramanian C, et al. Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migration. J Virol 2005;79(3):1559-68
    • (2005) J Virol , vol.79 , Issue.3 , pp. 1559-1568
    • Murakami, M.1    Lan, K.2    Subramanian, C.3
  • 116
    • 34249674439 scopus 로고    scopus 로고
    • NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-β (TGF-β) receptor-interacting protein, and negatively regulates TGF-β signaling
    • Seong HA, Jung H, Ha H, et al. NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-β (TGF-β) receptor-interacting protein, and negatively regulates TGF-β signaling. J Biol Chem 2007; 282(16):12075-96
    • (2007) J Biol Chem , vol.282 , Issue.16 , pp. 12075-12096
    • Seong, H.A.1    Jung, H.2    Ha, H.3
  • 117
    • 10744220955 scopus 로고    scopus 로고
    • Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis
    • D'Angelo A, Garzia L, Andre A, et al. Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis. Cancer Cell 2004;5(2):137-49
    • (2004) Cancer Cell , vol.5 , Issue.2 , pp. 137-149
    • D'Angelo, A.1    Garzia, L.2    Andre, A.3
  • 118
    • 33845703203 scopus 로고    scopus 로고
    • H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis
    • Garzia L, Roma C, Tata N, et al. H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis. J Bioenerg Biomembr 2006;38(3-4):205-13
    • (2006) J Bioenerg Biomembr , vol.38 , Issue.3-4 , pp. 205-213
    • Garzia, L.1    Roma, C.2    Tata, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.