MAPK signaling regulates endothelial cell assembly into networks and expression of MT1-MMP and MMP-2

American Journal of Physiology - Cell Physiology

Volumn 288, Issue 3 57-3, 2005, Pages

  Boyd, Pamela J ^a   Doyle, Jennifer ^a   Gee, Eric ^a   Pallan, Shelley ^a   Haas, Tara L ^a  

^a YORK UNIVERSITY   (Canada)

Author keywords

Angiogenesis; Extracellular matrix; Matrix metalloproteinases; Membrane type 1; Mitogen activated protein kinase; Transcriptional control

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COLLAGEN; GELATINASE A; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL AGGREGATION; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; COLLAGEN TYPE I; DNA-BINDING PROTEINS; EARLY GROWTH RESPONSE PROTEIN 1; ENDOTHELIAL CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IMMEDIATE-EARLY PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 13644259000     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00211.2004     Document Type: Article

References (48)

1. Aplin AE, Stewart SA, Assoian RK, and Juliano RL. Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1. J Cell Biol 153: 273-282, 2001.
2. Ausprunk D and Folkman J. Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc Res 14: 53-65, 1977.
3. Berra E, Milanini J, Richard DE, Le Gall M, Vinals F, Gothie E, Roux D, Pages G, and Pouyssegur J. Signaling angiogenesis via p42/p44 MAP kinase and hypoxia. Biochem Pharmacol 60: 1171-1178, 2000.
4. Birkedal-Hansen H. Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 7: 728-735, 1995.
5. Bogatcheva NV, Dudek SM, Garcia JGN, and Verin AD. Mitogen-activated protein kinases in endothelial pathophysiology. J Investig Med 51: 341-352, 2003.
6. Cukierman E, Pankov R, and Yamada KM. Cell interactions with three-dimensional matrices. Curr Opin Cell Biol 14: 633-639, 2002.
7. Davis GE and Camarillo CW. Regulation of endothelial cell morphogenesis by integrins, mechanical forces, and matrix guidance pathways. Exp Cell Res 216: 113-123, 1995.
8. Eliceiri BP, Klemke R, Stromblad S, and Cheresh DA. Integrin αvβ3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J Cell Biol 140: 1255-1263, 1998.
9. Fincham VJ, James M, Frame MC, and Winder SJ. Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src. EMBO J 19: 2911-2923, 2000.
10. Galvez BG, Matias-Roman S, Yanez-Mo M, Sanchez-Madrid F, and Arroyo AG. ECM regulates MT1-MMP localization with β1 or αvβ3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells. J Cell Biol 159: 509-521, 2002.
11. Haas TL, Davis SJ, and Madri JA. Three dimensional type I collagen lattices induce coordinate expression of matrix metalloproteinases MT1-MMP and MMP-2 in microvascular endothelial cells. J Biol Chem 273: 3604-3610, 1998.
12. Haas TL, Stitelman D, Davis SJ, Apte SS, and Madri JA. Egr-1 mediates extracellular matrix-driven transcription of membrane type 1 matrix metalloproteinase in endothelium. J Biol Chem 274: 22679-22685, 1999.
13. Huang C, Rajfur Z, Borchers C, Schaller MD, and Jacobson K. JNK phosphorylates paxillin and regulates cell migration. Nature 424: 219-223, 2003.
14. Hudlicka O. Mechanical factors involved in the growth of the heart and its blood vessels. Cell Mol Biol Res 40: 143-152, 1994.
15. Hudlicka O, Brown MD, and Egginton S. Angiogenesis in skeletal and cardiac muscle. Physiol Rev 72: 369-417, 1992.
16. Ingber DE and Folkman J. How does extracellular matrix control capillary morphogenesis? Cell 58: 803-805, 1989.
17. Issbrucker K, Marti HH, Hippenstiel S, Springmann G, Voswinckel R, Gaumann A, Breier G, Drexler HC, Suttorp N, and Clauss M. p38 MAP kinase-a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability. FASEB J 17: 262-264, 2003.
18. Javelaud D, Laboureau J, Gabison E, Verrecchia F, and Mauviel A. Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing. J Biol Chem 278: 24624-24628, 2003.
19. Kawamura S, Miyamoto S, and Brown JH. Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation. J Biol Chem 278: 31111-31117, 2003.
20. Khalil RA, Menice CB, Wang CL, and Morgan KG. Phosphotyrosine-dependent targeting of mitogen-activated protein kinase in differentiated contractile vascular cells. Circ Res 76: 1101-1108, 1995.
21. Kleiner DE and Stetler-Stevenson WG. Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem 218: 325-329, 1994.
22. Kurata H, Thant AA, Matsuo S, Senga T, Okazaki K, Hotta N, and Hamaguchi M. Constitutive activation of MAP kinase kinase (MEK1) is critical and sufficient for the activation of MMP-2. Exp Cell Res 254: 180-188, 2000.
23. Lambert CA, Colige AC, Munaut C, Lapiere CM, and Nusgens BV. Distinct pathways in the over-expression of matrix metalloproteinases in human fibroblasts by relaxation of mechanical tension. Matrix Biol 20: 397-408, 2001.
24. Langlois S, Gingras D, and Beliveau R. Membrane type 1-matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1-phosphate to induce endothelial cell migration and morphogenic differentiation. Blood 103: 3020-3028, 2004.
25. Leinweber BD, Leavis PC, Grabarek Z, Wang CL, and Morgan KG. Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of actin-binding proteins. Biochem J 344: 117-123, 1999.
26. Lewis TS, Shapiro PS, and Ahn NG. Signal transduction through MAP kinase cascades. Adv Cancer Res 74: 49-139, 1998.
27. Madri JA and Pratt BM. Endothelial cell-matrix interactions: in vitro models of angiogenesis. J Histochem Cytochem 34: 85-91, 1986.
28. Madri JA and Williams SK. Capillary endothelial cell cultures: phenotypic modulation by matrix components. J Cell Biol 97: 153-165, 1983.
29. Matsumoto T, Turesson I, Book M, Gerwins P, and Claesson-Welsh L. p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis. J Cell Biol 156: 149-160, 2002.
30. Montesano R, Soriano JV, Hosseini G, Pepper MS, and Schramek H. Constitutively active mitogen-activated protein kinase kinase MEK1 disrupts morphogenesis and induces an invasive phenotype in Madin-Darby canine kidney epithelial cells. Cell Growth Differ 10: 317-332, 1999.
31. Nguyen M, Arkell J, and Jackson CJ. Human endothelial gelatinases and angiogenesis. Int J Biochem Cell Biol 33: 960-970, 2001.
32. Ohno-Matsui K, Uetama T, Yoshida T, Hayano M, Itoh T, Morita I, and Mochizuki M. Reduced retinal angiogenesis in MMP-2-deficient mice. Invest Ophthalmol Vis Sci 44: 5370-5375, 2003.
33. Pepper MS and Mandriota SJ. Regulation of vascular endothelial growth factor receptor-2 (Flk-1) expression in vascular endothelial cells. Exp Cell Res 241: 414-425, 1998.
34. Rivilis I, Milkiewicz M, Boyd P, Goldstein J, Brown MD, Egginton S, Hansen FM, Hudlicka O, and Haas TL. Differential involvement of MMP-2 and VEGF during muscle stretch- versus shear stress-induced angiogenesis. Am J Physiol Heart Circ Physiol 283: H1430-H1438, 2002.
35. Shin EY, Kim SY, and Kim EG. c-Jun N-terminal kinase is involved in motility of endothelial cell. Ex Mol Med 33: 276-283, 2001.
36. Singh RP, Dhawan P, Golden C, Kapoor GS, and Mehta KD. One-way cross-talk between p38(MAPK) and p42/44(MAPK). Inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade. J Biol Chem 274: 19593-19600, 1999.
37. Stromblad S and Cheresh DA. Cell adhesion and angiogenesis. Trends Cell Biol 6: 462-468, 1996.
38. Tokuda H, Hirade K, Wang X, Oiso Y, and Kozawa O. Involvement of SAPK/JNK in basic fibrpblast growth factor-induced vascular endothelial growth factor release in osteoblasts. J Endocrinol 177: 101-107, 2003.
39. Vernon RB, Angello JC, Iruela-Arispe ML, Lane TF, and Sage EH. Reorganization of basement membrane matrices by cellular traction promotes the formation of cellular networks in vitro. Lab Invest 66: 536-547, 1992.
40. Vernon RB and Sage EH. Between molecules and morphology. Extracellular matrix and creation of vascular form. Am J Pathol 147: 873-883, 1995.
41. Vernon RB and Sage EH. Contraction of fibrillar type I collagen by endothelial cells: a study in vitro. J Cell Biochem 60: 185-197, 1996.
42. Wang X, Tokuda H, Hirade K, and Kozawa O. Stress-activated protein kinase/c-Jun N-terminal kinase (JNK) plays a part in endothelin-1-induced vascular endothelial growth factor synthesis in osteoblasts. J Cell Biochem 87: 417-423, 2002.
43. Woessner JF Jr. The family of matrix metalloproteinases. Ann NY Acad Sci 732: 11-21, 1994.
44. Wung BS, Cheng JJ, Chao YJ, Hsieh HJ, and Wang DL. Modulation of Ras/Raf/extracellular signal-regulated kinase pathway by reactive oxygen species is involved in cyclic strain-induced early growth response-1 gene expression in endothelial cells. Circ Res 84: 804-812, 1999.
45. Yang B, Cao DJ, Sainz I, Colman RW, and Guo YL. Different roles of ERK and p38 MAP kinases during tube formation from endothelial cells cultured in 3-dimensional collagen matrices. J Cell Physiol 200: 360-369, 2004.
46. Zentrich E, Han SY, Pessoa-Brandao L, Butterfield L, and Heasley LE. Collaboration of JNKs and ERKs in nerve growth factor regulation of the neurofilament light chain promoter in PC12 cells. J Biol Chem 277: 4110-4118, 2002.
47. Zhang C, Baumgartner RA, Yamada K, and Beaven MA. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells. Indications of communication between p38 and p42 MAP kinases. J Biol Chem 272: 13397-13402, 1997.
48. Zhang H, Shi X, Hampong M, Blanis L, and Pelech S. Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase. J Biol Chem 276: 6905-6908, 2001.