메뉴 건너뛰기




Volumn 97, Issue 9, 2005, Pages 632-642

Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

GESTAGEN; GLUCOCORTICOID RECEPTOR; HORMONE RECEPTOR; MEDROXYPROGESTERONE ACETATE; NUCLEOSIDE DIPHOSPHATE KINASE A; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; COMPLEMENTARY DNA; NUCLEOSIDE DIPHOSPHATE KINASE; TUMOR MARKER;

EID: 20444447134     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/dji111     Document Type: Article
Times cited : (111)

References (70)
  • 1
    • 0037264812 scopus 로고    scopus 로고
    • Metastasis suppressors alter the signal transduction of cancer cells
    • Steeg P. Metastasis suppressors alter the signal transduction of cancer cells. Nat Cancer Rev 2003;3:55-63.
    • (2003) Nat. Cancer Rev. , vol.3 , pp. 55-63
    • Steeg, P.1
  • 3
    • 0037980379 scopus 로고    scopus 로고
    • Metastasis suppressor pathways - An evolving paradigm
    • Shevde L, Welch D. Metastasis suppressor pathways - an evolving paradigm. Cancer Lett 2003; 198:1-20.
    • (2003) Cancer Lett. , vol.198 , pp. 1-20
    • Shevde, L.1    Welch, D.2
  • 5
    • 0025753514 scopus 로고
    • Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells
    • Leone A, Flatow U, King CR, Sandeen MA, Margulies IM, Liotta LA, et al. Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells. Cell 1991;65:25-35.
    • (1991) Cell , vol.65 , pp. 25-35
    • Leone, A.1    Flatow, U.2    King, C.R.3    Sandeen, M.A.4    Margulies, I.M.5    Liotta, L.A.6
  • 7
    • 0027304816 scopus 로고
    • Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: Effects on tumor metastatic potential, colonization, and enzymatic activity
    • Leone A, Flatow U, VanHoutte K, Steeg PS. Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: Effects on tumor metastatic potential, colonization, and enzymatic activity. Oncogene 1993;8:2325-33.
    • (1993) Oncogene , vol.8 , pp. 2325-2333
    • Leone, A.1    Flatow, U.2    VanHoutte, K.3    Steeg, P.S.4
  • 8
    • 0032900276 scopus 로고    scopus 로고
    • Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A 31P nuclear magnetic resonance study in vivo and in vitro
    • Bhujwalla Z, Aboagye E, Gilles R, Chack V, Mendola C, Backer J. Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: a 31P nuclear magnetic resonance study in vivo and in vitro. Magnetic Res Med 1999;41:897-903.
    • (1999) Magnetic Res. Med. , vol.41 , pp. 897-903
    • Bhujwalla, Z.1    Aboagye, E.2    Gilles, R.3    Chack, V.4    Mendola, C.5    Backer, J.6
  • 9
    • 0030615195 scopus 로고    scopus 로고
    • nm23 - Relationship to the metastatic potential of breast carcinoma cell lines, primary human xenografts and lymph node negative breast carcinoma patients
    • Russell R, Geisinger K, Mehta R, White W, Shelton B, Kute T. nm23 - Relationship to the metastatic potential of breast carcinoma cell lines, primary human xenografts and lymph node negative breast carcinoma patients. Cancer 1997;79:1158-65.
    • (1997) Cancer , vol.79 , pp. 1158-1165
    • Russell, R.1    Geisinger, K.2    Mehta, R.3    White, W.4    Shelton, B.5    Kute, T.6
  • 10
    • 13344283439 scopus 로고    scopus 로고
    • Metastatic potential of rat mammary adenocarcinoma cells associated with decreased expression of nucleoside diphosphate kinase/nm23: Reduction by transfection of NDP Kinase a isoform, an nm23-H2 gene homolog
    • Fukuda M, Ishii A, Yasutomo Y, Shimada N, Ishikawa N, Hanai N, et al. Metastatic potential of rat mammary adenocarcinoma cells associated with decreased expression of nucleoside diphosphate kinase/nm23: reduction by transfection of NDP Kinase a isoform, an nm23-H2 gene homolog. Int J Cancer 1996;65:531-7.
    • (1996) Int. J. Cancer , vol.65 , pp. 531-537
    • Fukuda, M.1    Ishii, A.2    Yasutomo, Y.3    Shimada, N.4    Ishikawa, N.5    Hanai, N.6
  • 11
    • 0028953272 scopus 로고
    • Two isotypes of murine nm23/nucleoside diphosphate kinase, nm23-M1 and nm23-M2, are involved in metastatic suppression of a murine melanoma line
    • Baba H, Urano T, Okada K, Furukawa K, Nakayama E, Tanaka H, et al. Two isotypes of murine nm23/nucleoside diphosphate kinase, nm23-M1 and nm23-M2, are involved in metastatic suppression of a murine melanoma line. Cancer Res 1995;55:1977-81.
    • (1995) Cancer Res. , vol.55 , pp. 1977-1981
    • Baba, H.1    Urano, T.2    Okada, K.3    Furukawa, K.4    Nakayama, E.5    Tanaka, H.6
  • 12
    • 0031002950 scopus 로고    scopus 로고
    • Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (nm23)
    • Miele ME, Rosa AD, Lee JH, Hicks DJ, Dennis JU, Steeg PS, et al. Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (nm23). Clin Exp Metastasis 1997;15:259-65.
    • (1997) Clin. Exp. Metastasis , vol.15 , pp. 259-265
    • Miele, M.E.1    Rosa, A.D.2    Lee, J.H.3    Hicks, D.J.4    Dennis, J.U.5    Steeg, P.S.6
  • 13
    • 0028948137 scopus 로고
    • Effects of cytokine mediated modulation of Nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells
    • Parhar RS, Shi Y, Zou M, Farid NR, Ernst P, Al-Sedairy S. Effects of cytokine mediated modulation of Nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells. Int J Cancer 1995;60:204-10.
    • (1995) Int. J. Cancer , vol.60 , pp. 204-210
    • Parhar, R.S.1    Shi, Y.2    Zou, M.3    Farid, N.R.4    Ernst, P.5    Al-Sedairy, S.6
  • 14
    • 0032107072 scopus 로고    scopus 로고
    • Reduced metastatic potential and c-myc overexpression of colon adenocarcinoma cells (Colon 26 line) transfected with nm23-R2 rat nucleoside diphosphate kinase a isoform
    • Tagashira H, Hamazaki K, Tanaka N, Gao C, Namba M. Reduced metastatic potential and c-myc overexpression of colon adenocarcinoma cells (Colon 26 line) transfected with nm23-R2 rat nucleoside diphosphate kinase a isoform. Int J Mol Med 1998;2:65-8.
    • (1998) Int. J. Mol. Med. , vol.2 , pp. 65-68
    • Tagashira, H.1    Hamazaki, K.2    Tanaka, N.3    Gao, C.4    Namba, M.5
  • 15
    • 18744421905 scopus 로고    scopus 로고
    • Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent proliferative activity in culture
    • Miyazaki H, Fukuda M, Ishijima Y, Negishi A, Hirayama R, Ishikawa N, et al. Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent proliferative activity in culture. Clin Cancer Res 1999;5:4301-7.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 4301-4307
    • Miyazaki, H.1    Fukuda, M.2    Ishijima, Y.3    Negishi, A.4    Hirayama, R.5    Ishikawa, N.6
  • 16
    • 0347382319 scopus 로고    scopus 로고
    • nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation
    • Suzuki E, Ota T, Tsukuda K, Okita A, Matsuoka K, Murakami M, et al. nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation. Int J Cancer 2004;108:207-11.
    • (2004) Int. J. Cancer , vol.108 , pp. 207-211
    • Suzuki, E.1    Ota, T.2    Tsukuda, K.3    Okita, A.4    Matsuoka, K.5    Murakami, M.6
  • 17
    • 0027193360 scopus 로고
    • Inhibition of cell motility after nm23 transfection of human and murine tumor cells
    • Kantor JD, McCormick B, Steeg PS, Zetter BR. Inhibition of cell motility after nm23 transfection of human and murine tumor cells. Cancer Res 1993;53:1971-3.
    • (1993) Cancer Res. , vol.53 , pp. 1971-1973
    • Kantor, J.D.1    McCormick, B.2    Steeg, P.S.3    Zetter, B.R.4
  • 18
    • 0028576840 scopus 로고
    • A novel function for Nm23: Overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest
    • Howlett AR, Petersen OW, Steeg PS, Bissell MJ. A novel function for Nm23: overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest. J Natl Cancer Inst 1994;86: 1838-44.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1838-1844
    • Howlett, A.R.1    Petersen, O.W.2    Steeg, P.S.3    Bissell, M.J.4
  • 19
    • 7344257797 scopus 로고    scopus 로고
    • Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines
    • Russell R, Pedersen A, Kantor J, Geisinger K, Long R, Zbieranski N, et al. Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines. Br J Cancer 1998;78:710-7.
    • (1998) Br. J. Cancer , vol.78 , pp. 710-717
    • Russell, R.1    Pedersen, A.2    Kantor, J.3    Geisinger, K.4    Long, R.5    Zbieranski, N.6
  • 20
    • 0034234253 scopus 로고    scopus 로고
    • Reproductive state of rat mammary gland stroma modulates human breast cancer cell migration and invasion
    • Bemis L, Schedin P. Reproductive state of rat mammary gland stroma modulates human breast cancer cell migration and invasion. Cancer Res 2000;60:3414-8.
    • (2000) Cancer Res. , vol.60 , pp. 3414-3418
    • Bemis, L.1    Schedin, P.2
  • 21
    • 0345736991 scopus 로고    scopus 로고
    • Restoring functions of tumor suppressors with small molecules
    • Smukste I, Stockwell B. Restoring functions of tumor suppressors with small molecules. Cancer Cell 2003;4:419-20.
    • (2003) Cancer Cell , vol.4 , pp. 419-420
    • Smukste, I.1    Stockwell, B.2
  • 22
    • 0028018356 scopus 로고
    • NME1 protein expression and loss of heterozygosity mutations in primary human breast tumors
    • Cropp C, Lidereau R, Leone A, Liscia D, Cappa A, Campbell G, et al. NME1 protein expression and loss of heterozygosity mutations in primary human breast tumors. J Natl Cancer Inst 1994;86:1167-9.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1167-1169
    • Cropp, C.1    Lidereau, R.2    Leone, A.3    Liscia, D.4    Cappa, A.5    Campbell, G.6
  • 23
    • 0035266181 scopus 로고    scopus 로고
    • Elevation of breast carcinoma nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition
    • Hartsough M, Clare S, Mair M, Elkahloun A, Sgroi D, Osborne C, et al. Elevation of breast carcinoma nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition. Cancer Res 2001;61:2320-7.
    • (2001) Cancer Res. , vol.61 , pp. 2320-2327
    • Hartsough, M.1    Clare, S.2    Mair, M.3    Elkahloun, A.4    Sgroi, D.5    Osborne, C.6
  • 24
    • 0036155880 scopus 로고    scopus 로고
    • Activation of antimetastatic Nm23-H1 gene expression by estrogen and its a-receptor
    • Lin K, Wang W, Wu Y, Cheng S. Activation of antimetastatic Nm23-H1 gene expression by estrogen and its a-receptor. Endocrinology 2002;143:467-75.
    • (2002) Endocrinology , vol.143 , pp. 467-475
    • Lin, K.1    Wang, W.2    Wu, Y.3    Cheng, S.4
  • 25
    • 0033971620 scopus 로고    scopus 로고
    • Effects of all-trans retinoic acid and epidermal growth factor on the expression of nm23-H1 in human hepatocarcinoma cells
    • Liu F, Qi HL, Chen HL. Effects of all-trans retinoic acid and epidermal growth factor on the expression of nm23-H1 in human hepatocarcinoma cells. J Cancer Res Clin Oncol 2000;126:85-90.
    • (2000) J. Cancer Res. Clin. Oncol. , vol.126 , pp. 85-90
    • Liu, F.1    Qi, H.L.2    Chen, H.L.3
  • 26
    • 0031933938 scopus 로고
    • The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells
    • Jiang W, Hiscox S, Bryce R, Horrobin D, Mansel R. The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells. Br J Cancer 1988;77:731-8.
    • (1988) Br. J. Cancer , vol.77 , pp. 731-738
    • Jiang, W.1    Hiscox, S.2    Bryce, R.3    Horrobin, D.4    Mansel, R.5
  • 27
    • 6444244601 scopus 로고    scopus 로고
    • The effects of acetylsalicylic acid on proliferation, apoptosis, and invasion of cyclooxygenase-2 negative colon cancer cells
    • Yu HG, Huang JA, Yang YN, Huang H, Luo HS, Yu JP, et al. The effects of acetylsalicylic acid on proliferation, apoptosis, and invasion of cyclooxygenase-2 negative colon cancer cells. Eur J Clin Invest 2002;32:838-46.
    • (2002) Eur. J. Clin. Invest. , vol.32 , pp. 838-846
    • Yu, H.G.1    Huang, J.A.2    Yang, Y.N.3    Huang, H.4    Luo, H.S.5    Yu, J.P.6
  • 28
    • 0036186431 scopus 로고    scopus 로고
    • MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines
    • Ouatas T, Clare S, Hartsough M, DeLaRosa A, Steeg P. MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines. Clin Exp Metastasis 2002;19:35-42.
    • (2002) Clin. Exp. Metastasis , vol.19 , pp. 35-42
    • Ouatas, T.1    Clare, S.2    Hartsough, M.3    DeLaRosa, A.4    Steeg, P.5
  • 29
    • 0141568002 scopus 로고    scopus 로고
    • Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor expression in metastatic human breast carcinoma cells: New uses for old compounds
    • Ouatas T, Halverson D, Steeg P. Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor expression in metastatic human breast carcinoma cells: new uses for old compounds. Clin Cancer Res 2003;9:3763-72.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3763-3772
    • Ouatas, T.1    Halverson, D.2    Steeg, P.3
  • 30
    • 0028946370 scopus 로고
    • Depot medroxyprogesterone acetate and breast cancer. A pooled analysis of the World Health Organization and New Zealand studies
    • Skegg D, Noonan E, Paul C, Spears G, Meirik O, Thomas D. Depot medroxyprogesterone acetate and breast cancer. A pooled analysis of the World Health Organization and New Zealand studies. JAMA 1995;273: 799-804.
    • (1995) JAMA , vol.273 , pp. 799-804
    • Skegg, D.1    Noonan, E.2    Paul, C.3    Spears, G.4    Meirik, O.5    Thomas, D.6
  • 31
    • 0034079089 scopus 로고    scopus 로고
    • Systematic reviews of chemotherapy and endocrine therapy in metastatic breast cancer
    • Stockler M, Wilcken N, Ghersi D, Simes R. Systematic reviews of chemotherapy and endocrine therapy in metastatic breast cancer. Cancer Treat Rev 2000;26:151-68.
    • (2000) Cancer Treat. Rev. , vol.26 , pp. 151-168
    • Stockler, M.1    Wilcken, N.2    Ghersi, D.3    Simes, R.4
  • 32
    • 17844390913 scopus 로고    scopus 로고
    • Adjuvant high dose medroxyprogesterone acetate for early breast cancer: 13 years update in a multicentre randomized trial
    • Focan C, Beauduin M, Salamon E, Greve JD, deWasch G, Lobelle J, et al. Adjuvant high dose medroxyprogesterone acetate for early breast cancer: 13 years update in a multicentre randomized trial. Br J Cancer 2001;85:1-8.
    • (2001) Br. J. Cancer , vol.85 , pp. 1-8
    • Focan, C.1    Beauduin, M.2    Salamon, E.3    Greve, J.D.4    deWasch, G.5    Lobelle, J.6
  • 33
    • 17344390833 scopus 로고    scopus 로고
    • A randomized study comparing oral and standard regimens for metastatic breast cancer
    • Hori T, Kodama H, Nishimura S, Hatano T, Okamura R, Fujii K, et al. A randomized study comparing oral and standard regimens for metastatic breast cancer. Oncol Rep 2001;8:1067-71.
    • (2001) Oncol. Rep. , vol.8 , pp. 1067-1071
    • Hori, T.1    Kodama, H.2    Nishimura, S.3    Hatano, T.4    Okamura, R.5    Fujii, K.6
  • 34
    • 0030814481 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate addition or substitution for tamoxifen in advanced tamoxifen-resistant breast cancer: A Phase III randomized trial
    • Bryne M, Gebski V, Forbes J, Tattersall M, Simes R, Coates A, et al. Medroxyprogesterone acetate addition or substitution for tamoxifen in advanced tamoxifen-resistant breast cancer: A Phase III randomized trial. J Clin Oncol 1997;15:3141-8.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3141-3148
    • Bryne, M.1    Gebski, V.2    Forbes, J.3    Tattersall, M.4    Simes, R.5    Coates, A.6
  • 35
    • 0032768738 scopus 로고    scopus 로고
    • Androgen receptor agonist activity of the synthetic progestin medroxyprogesterone acetate, in human breast cancer cells
    • Bentel J, Birrell S, Pickering M, Holds D, Horsfall D, Tilley W. Androgen receptor agonist activity of the synthetic progestin medroxyprogesterone acetate, in human breast cancer cells. Mol Cell Endocrinol 1999; 154:11-20.
    • (1999) Mol. Cell Endocrinol. , vol.154 , pp. 11-20
    • Bentel, J.1    Birrell, S.2    Pickering, M.3    Holds, D.4    Horsfall, D.5    Tilley, W.6
  • 36
    • 0029863026 scopus 로고    scopus 로고
    • Binding specificity of medroxyprogesterone acetate and proligestone for the progesterone and glucocorticoid receptor in the dog
    • Selman P, Wolfswinkel J, Mol J. Binding specificity of medroxyprogesterone acetate and proligestone for the progesterone and glucocorticoid receptor in the dog. Steroids 1996;61:133-7.
    • (1996) Steroids , vol.61 , pp. 133-137
    • Selman, P.1    Wolfswinkel, J.2    Mol, J.3
  • 37
    • 0033310360 scopus 로고    scopus 로고
    • Dissociative glucocorticoid activity of medroxyprogesterone acetate in normal human lymphocytes
    • Bamberger C, Else T, Bamberger A, Beil F, Shulte H. Dissociative glucocorticoid activity of medroxyprogesterone acetate in normal human lymphocytes. J Biol Chem 1999;84:4055-61.
    • (1999) J. Biol. Chem. , vol.84 , pp. 4055-4061
    • Bamberger, C.1    Else, T.2    Bamberger, A.3    Beil, F.4    Shulte, H.5
  • 38
    • 0032820637 scopus 로고    scopus 로고
    • Progesterone mediates decreases in uterine smooth muscle cell interelukin-1a by a mechanism involving decreased stability of IL-1a mRNA
    • Lan L, Vinci J, Melendez J, Jeffrey J, Wilcox B. Progesterone mediates decreases in uterine smooth muscle cell interelukin-1a by a mechanism involving decreased stability of IL-1a mRNA. Mol Cell Endocrinol 1999;155:123-33.
    • (1999) Mol. Cell Endocrinol. , vol.155 , pp. 123-133
    • Lan, L.1    Vinci, J.2    Melendez, J.3    Jeffrey, J.4    Wilcox, B.5
  • 39
    • 0034802111 scopus 로고    scopus 로고
    • Up-regulation of p27Kip1 by progestins is involved in the growth suppression of the normal and malignant human endometrial glandular cells
    • Shiozawa T, Horiuchi A, Kato K, Obinata M, Konishi I, Fuji S, et al. Up-regulation of p27Kip1 by progestins is involved in the growth suppression of the normal and malignant human endometrial glandular cells. Endocrinology 2001;142:4182-8.
    • (2001) Endocrinology , vol.142 , pp. 4182-4188
    • Shiozawa, T.1    Horiuchi, A.2    Kato, K.3    Obinata, M.4    Konishi, I.5    Fuji, S.6
  • 40
    • 0035141188 scopus 로고    scopus 로고
    • Adjuvant chemo-hormonal therapy with cyclophosphamide, doxorubicin and 5-fluroruacil (CAF) with or without medroxyprogesterone acetate (MPA) for node-positive cancer patients, update at 12 years follow up
    • Hupperets P, Wils J, Volovics L, Schouten L, Fickers M, Bron H, et al. Adjuvant chemo-hormonal therapy with cyclophosphamide, doxorubicin and 5-fluroruacil (CAF) with or without medroxyprogesterone acetate (MPA) for node-positive cancer patients, update at 12 years follow up. The Breast 2001;10:35-7.
    • (2001) The Breast , vol.10 , pp. 35-37
    • Hupperets, P.1    Wils, J.2    Volovics, L.3    Schouten, L.4    Fickers, M.5    Bron, H.6
  • 41
    • 0034242440 scopus 로고    scopus 로고
    • Precision and accuracy of dual-energy X-ray absorptiometry for determining in vivo body composition of mice
    • Nagy T, Clair A. Precision and accuracy of dual-energy X-ray absorptiometry for determining in vivo body composition of mice. Obes Res 2000;8:392-8.
    • (2000) Obes. Res. , vol.8 , pp. 392-398
    • Nagy, T.1    Clair, A.2
  • 42
    • 33645762226 scopus 로고
    • A sharper Bonferroni procedure for multiple tests of significance
    • Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometrika 1988;75:800-2.
    • (1988) Biometrika , vol.75 , pp. 800-802
    • Hochberg, Y.1
  • 43
    • 0001822394 scopus 로고
    • The misuse of ratios, indices, and percentages in ecophysiological research
    • Packard G, Boardman T. The misuse of ratios, indices, and percentages in ecophysiological research. Physiol Zool 1988;61:1-9.
    • (1988) Physiol. Zool. , vol.61 , pp. 1-9
    • Packard, G.1    Boardman, T.2
  • 44
    • 0030859398 scopus 로고    scopus 로고
    • Predictive value of serum medroxyprogesterone acetate concentration for response in advanced or recurrent breast cancer
    • Nishimura R, Nagao K, Matsuda M, Baba K, Matsuoka Y, Yamashita H, et al. Predictive value of serum medroxyprogesterone acetate concentration for response in advanced or recurrent breast cancer. Eur J Cancer 1997;33:1407-12.
    • (1997) Eur. J. Cancer , vol.33 , pp. 1407-1412
    • Nishimura, R.1    Nagao, K.2    Matsuda, M.3    Baba, K.4    Matsuoka, Y.5    Yamashita, H.6
  • 45
    • 0026684209 scopus 로고
    • Pharmacokinetics and pharmacodynamics of medroxyprogesterone acetate in advance breast cancer patients
    • Etienne M, Milano G, Frenay M, Renee N, Francois E, Thyss A, et al. Pharmacokinetics and pharmacodynamics of medroxyprogesterone acetate in advance breast cancer patients. J Clin Oncol 1992;10:1176-82.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1176-1182
    • Etienne, M.1    Milano, G.2    Frenay, M.3    Renee, N.4    Francois, E.5    Thyss, A.6
  • 46
    • 0023929173 scopus 로고
    • Clinical trial of high dose oral medroxyprogesterone acetate in the treatment of metastatic breast cancer and review of the literature
    • Davila E, Vogel C, East D, Cairns V, Hilsenbeck S. Clinical trial of high dose oral medroxyprogesterone acetate in the treatment of metastatic breast cancer and review of the literature. Cancer 1988;61:2161-7.
    • (1988) Cancer , vol.61 , pp. 2161-2167
    • Davila, E.1    Vogel, C.2    East, D.3    Cairns, V.4    Hilsenbeck, S.5
  • 47
    • 0023582881 scopus 로고
    • High dose versus low dose medroxyprogesterone acetate: A randomized trial in advanced breast cancer
    • Gallagher CJ, Cairnduff F, Smith IE. High dose versus low dose medroxyprogesterone acetate: a randomized trial in advanced breast cancer. Eur J Cancer Clin Oncol 1987;23:1895-900.
    • (1987) Eur. J. Cancer Clin. Oncol. , vol.23 , pp. 1895-1900
    • Gallagher, C.J.1    Cairnduff, F.2    Smith, I.E.3
  • 48
    • 0033006547 scopus 로고    scopus 로고
    • A randomized controlled comparative study of oral medroxyprogesterone acetate 1,200 and 600 mg in patients with advanced or recurrent breast cancer
    • Koyama H, Tominaga T, Asaishi K, Abe R, Iino Y, Enomoto K, et al. A randomized controlled comparative study of oral medroxyprogesterone acetate 1,200 and 600 mg in patients with advanced or recurrent breast cancer. Oncology 1999;56:283-90.
    • (1999) Oncology , vol.56 , pp. 283-290
    • Koyama, H.1    Tominaga, T.2    Asaishi, K.3    Abe, R.4    Iino, Y.5    Enomoto, K.6
  • 49
    • 0036345830 scopus 로고    scopus 로고
    • Pharmacologic doses of medroxyprogesterone may cause bone loss through glucocorticoid activity: An hypothesis
    • Ishida Y, Heersche J. Pharmacologic doses of medroxyprogesterone may cause bone loss through glucocorticoid activity: an hypothesis. Osteoporos Int 2002;13:601-5.
    • (2002) Osteoporos. Int. , vol.13 , pp. 601-605
    • Ishida, Y.1    Heersche, J.2
  • 50
    • 0031878398 scopus 로고    scopus 로고
    • Promoter effect of medroxyprogesterone acetate (MPA) in N-methyl-N-nitrosourea (MNU) induced mammary tumors in BALB/c mice
    • Pazos P, Lanari C, Elizalde P, Montecchia F, Charreau E, Molinolo A. Promoter effect of medroxyprogesterone acetate (MPA) in N-methyl-N-nitrosourea (MNU) induced mammary tumors in BALB/c mice. Carcinogenesis 1998;19:529-31.
    • (1998) Carcinogenesis , vol.19 , pp. 529-531
    • Pazos, P.1    Lanari, C.2    Elizalde, P.3    Montecchia, F.4    Charreau, E.5    Molinolo, A.6
  • 51
    • 0022975342 scopus 로고
    • Induction of mammary adenocarcinomas by medroxyprogesterone acetate in BALB/c mice
    • Lanari C, Molonolo A, Pasqualini C. Induction of mammary adenocarcinomas by medroxyprogesterone acetate in BALB/c mice. Cancer Lett 1986;33:215-33.
    • (1986) Cancer Lett. , vol.33 , pp. 215-233
    • Lanari, C.1    Molonolo, A.2    Pasqualini, C.3
  • 53
    • 0142206316 scopus 로고    scopus 로고
    • Metastasis suppressed C8161 melanoma cells arrest in lung but fail to proliferate
    • Goldberg S, Harms J, Quon K, Welch D. Metastasis suppressed C8161 melanoma cells arrest in lung but fail to proliferate. Clin Exp Metastasis 1999;58:4963-9.
    • (1999) Clin. Exp. Metastasis , vol.58 , pp. 4963-4969
    • Goldberg, S.1    Harms, J.2    Quon, K.3    Welch, D.4
  • 54
    • 1442299105 scopus 로고    scopus 로고
    • Glucocorticoid and mineralocorticoid cross-talk with progesterone receptor to induce focal adhesions and growth inhibition in breast cancer cells
    • Leo J, Guo C, Woon C, Aw S, Lin V. Glucocorticoid and mineralocorticoid cross-talk with progesterone receptor to induce focal adhesions and growth inhibition in breast cancer cells. Endocrinology 2004;145:1314-21.
    • (2004) Endocrinology , vol.145 , pp. 1314-1321
    • Leo, J.1    Guo, C.2    Woon, C.3    Aw, S.4    Lin, V.5
  • 55
    • 0037568442 scopus 로고    scopus 로고
    • Progesterone induces cellular differentiation in MDA-MB-231 breast cancer cells transfected with progesterone receptor complementary DNA
    • Lin V, Jin R, Tan PH, Aw SE, Woon CT, Bay BH. Progesterone induces cellular differentiation in MDA-MB-231 breast cancer cells transfected with progesterone receptor complementary DNA. Am J Pathol 2003;162: 1781-7.
    • (2003) Am. J. Pathol. , vol.162 , pp. 1781-1787
    • Lin, V.1    Jin, R.2    Tan, P.H.3    Aw, S.E.4    Woon, C.T.5    Bay, B.H.6
  • 56
    • 0034059206 scopus 로고    scopus 로고
    • Cooperation of p27Kip1 and p18Ink4c in progestin-mediated cell cycle arrest in T-47D breast cancer cells
    • Swarbrick A, Lee C, Sutherland R, Musgrove E. Cooperation of p27Kip1 and p18Ink4c in progestin-mediated cell cycle arrest in T-47D breast cancer cells. Mol Cell Biol 2000;20:2581-91.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 2581-2591
    • Swarbrick, A.1    Lee, C.2    Sutherland, R.3    Musgrove, E.4
  • 57
    • 0142151083 scopus 로고    scopus 로고
    • Overexpression of wild-type p53 gene renders MCF-7 breast cancer cells more sensitive to the antiproliferative effect of progesterone
    • Alkhalaf M, El-Mowafy A. Overexpression of wild-type p53 gene renders MCF-7 breast cancer cells more sensitive to the antiproliferative effect of progesterone. J Endocrinol 2003;179:55-62.
    • (2003) J. Endocrinol. , vol.179 , pp. 55-62
    • Alkhalaf, M.1    El-Mowafy, A.2
  • 58
    • 0036721112 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 is critical for a progestin-induced growth inhibition in MCF-7 breast cancer cells
    • Ahola T, Manninen T, Alkio N, Ylikomi T. G protein-coupled receptor 30 is critical for a progestin-induced growth inhibition in MCF-7 breast cancer cells. Endocrinology 2002;143:3376-84.
    • (2002) Endocrinology , vol.143 , pp. 3376-3384
    • Ahola, T.1    Manninen, T.2    Alkio, N.3    Ylikomi, T.4
  • 59
    • 0032880979 scopus 로고    scopus 로고
    • Suppression of parathyroid hormone-related protein messenger RNA expression by medroxyprogesterone acetate in breast cancer tissues
    • Sugimoto T, Shiba E, Watanabe T, Takai S. Suppression of parathyroid hormone-related protein messenger RNA expression by medroxyprogesterone acetate in breast cancer tissues. Breast Cancer Res Treat 1999;56: 11-23.
    • (1999) Breast Cancer Res. Treat. , vol.56 , pp. 11-23
    • Sugimoto, T.1    Shiba, E.2    Watanabe, T.3    Takai, S.4
  • 60
    • 0033729438 scopus 로고    scopus 로고
    • Biphasic effect of medroxyprogesterone acetate (MPA) treatment on proliferation and cyclin D1 gene transcription in T47D breast cancer cells
    • Thuneke I, Shulte H, Bamberger A. Biphasic effect of medroxyprogesterone acetate (MPA) treatment on proliferation and cyclin D1 gene transcription in T47D breast cancer cells. Breast Cancer Res Treat 2000; 63:243-8.
    • (2000) Breast Cancer Res. Treat. , vol.63 , pp. 243-248
    • Thuneke, I.1    Shulte, H.2    Bamberger, A.3
  • 61
    • 0025868089 scopus 로고
    • Effects of tamoxifen, medroxyprogesterone acetate and estradiol on tumor growth and oncogene expression in MCF-7 breast cancer cell line transplanted into nude mice
    • Mizukami Y, Tajiri K, Nonomura A, Nogichi M, Taniya T, Koyasaki N, et al. Effects of tamoxifen, medroxyprogesterone acetate and estradiol on tumor growth and oncogene expression in MCF-7 breast cancer cell line transplanted into nude mice. Anticancer Res 1991;11:1333-8.
    • (1991) Anticancer Res. , vol.11 , pp. 1333-1338
    • Mizukami, Y.1    Tajiri, K.2    Nonomura, A.3    Nogichi, M.4    Taniya, T.5    Koyasaki, N.6
  • 62
    • 0032888381 scopus 로고    scopus 로고
    • Anti-angiogenic activity of a novel synthetic agent, 9-a-flurormedroxyprogesterone acetate
    • Yamaji T, Tsuboi H, Murata N, Uchida M, Kohno T, Sugino E, et al. Anti-angiogenic activity of a novel synthetic agent, 9-a-flurormedroxyprogesterone acetate. Cancer Lett 1999;145:107-14.
    • (1999) Cancer Lett. , vol.145 , pp. 107-114
    • Yamaji, T.1    Tsuboi, H.2    Murata, N.3    Uchida, M.4    Kohno, T.5    Sugino, E.6
  • 63
    • 0042122478 scopus 로고    scopus 로고
    • The effects of epirubicin hydrochloride (EPI) plus pretreatment of medroxyprogesterone acetate (MPA) on FM3A breast cancer cells transplanted in female C3H/He mice
    • Yuyama Y, Yagihashi A, Hirata K, Suzuki Y, Ohmura T, Okazaki M, et al. The effects of epirubicin hydrochloride (EPI) plus pretreatment of medroxyprogesterone acetate (MPA) on FM3A breast cancer cells transplanted in female C3H/He mice. In Vivo 2003;17:251-4.
    • (2003) Vivo , vol.17 , pp. 251-254
    • Yuyama, Y.1    Yagihashi, A.2    Hirata, K.3    Suzuki, Y.4    Ohmura, T.5    Okazaki, M.6
  • 64
    • 0021966814 scopus 로고
    • Endocrine effects of medroxyprogesterone acetate: Relation between plasma levels and suppression of adrenal steroids in patients with breast cancer
    • vanVeelen H, Willemse P, Sleijfer D, Sluiter W, Doorenbos H. Endocrine effects of medroxyprogesterone acetate: relation between plasma levels and suppression of adrenal steroids in patients with breast cancer. Cancer Treat Rep 1985;9:977-83.
    • (1985) Cancer Treat. Rep. , vol.9 , pp. 977-983
    • vanVeelen, H.1    Willemse, P.2    Sleijfer, D.3    Sluiter, W.4    Doorenbos, H.5
  • 65
    • 0036323295 scopus 로고    scopus 로고
    • Hepatocyte growth factor is required for progestin-induced epithelial cell proliferation and alveolar-like morphogenesis in serum-free culture of normal mammary epithelial cells
    • Sunil N, Bennett J, Haslam S. Hepatocyte growth factor is required for progestin-induced epithelial cell proliferation and alveolar-like morphogenesis in serum-free culture of normal mammary epithelial cells. Endocrinology 2002;143:2953-60.
    • (2002) Endocrinology , vol.143 , pp. 2953-2960
    • Sunil, N.1    Bennett, J.2    Haslam, S.3
  • 66
    • 0037371863 scopus 로고    scopus 로고
    • Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells
    • Ballare C, Uhrig M, Bechtold T, Sancho E, DiDomenico M, Migliaccio A, et al. Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells. Mol Cell Biol 2003;23:1994-2008.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 1994-2008
    • Ballare, C.1    Uhrig, M.2    Bechtold, T.3    Sancho, E.4    DiDomenico, M.5    Migliaccio, A.6
  • 67
    • 0038583811 scopus 로고    scopus 로고
    • The effect of progesterone and synthetic progestins on serum-and estradiol-stimulated proliferation of human breast cancer cells
    • Seeger H, Wallwiener D, Mueck A. The effect of progesterone and synthetic progestins on serum-and estradiol-stimulated proliferation of human breast cancer cells. Horm Metab Res 2003;35:76-80.
    • (2003) Horm. Metab. Res. , vol.35 , pp. 76-80
    • Seeger, H.1    Wallwiener, D.2    Mueck, A.3
  • 68
    • 85047682043 scopus 로고    scopus 로고
    • Overlapping but distinct gene regulation profiles by glucocorticoids and progestins in human breast cancer cells
    • Wan Y, Nordeen S. Overlapping but distinct gene regulation profiles by glucocorticoids and progestins in human breast cancer cells. Mol Endocrinol 2002;16:1204-14.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1204-1214
    • Wan, Y.1    Nordeen, S.2
  • 69
    • 0036668765 scopus 로고    scopus 로고
    • Differential activation of the IkBa and mouse mammary tumor virus promoters by progesterone and glucocorticoid receptors
    • Deroo B, Archer T. Differential activation of the IkBa and mouse mammary tumor virus promoters by progesterone and glucocorticoid receptors. J Steroid Biochem Mol Biol 2002;81:309-17.
    • (2002) J. Steroid Biochem. Mol. Biol. , vol.81 , pp. 309-317
    • Deroo, B.1    Archer, T.2
  • 70
    • 0035816687 scopus 로고    scopus 로고
    • Transactivation specificity of glucocorticoid versus progesterone receptors
    • Song LN, Huse B, Rusconi Simons SS Jr. Transactivation specificity of glucocorticoid versus progesterone receptors. J Biol Chem 2001; 276:24806-16.
    • (2001) J. Biol. Chem. , vol.276 , pp. 24806-24816
    • Song, L.N.1    Huse, B.2    Rusconi Simons Jr., S.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.