-
1
-
-
33846205638
-
Nikolai N. Anichkov and his theory of atherosclerosis
-
Konstantinov, I.E., Mejevoi, N., and Anichkov, N.M. 2006. Nikolai N. Anichkov and his theory of atherosclerosis. Tex. Heart Inst. J. 33:417-423.
-
(2006)
Tex. Heart Inst. J
, vol.33
, pp. 417-423
-
-
Konstantinov, I.E.1
Mejevoi, N.2
Anichkov, N.M.3
-
2
-
-
0030931962
-
Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase
-
Weinstock, P.H., et al. 1997. Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase. Proc. Natl. Acad. Sci. U. S. A. 94:10261-10266.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A
, vol.94
, pp. 10261-10266
-
-
Weinstock, P.H.1
-
3
-
-
0036460675
-
Lipoprotein lipase: Structure, function, regulation, and role in disease
-
Mead, J.R., Irvine, S.A., and Ramji, D.P. 2002. Lipoprotein lipase: structure, function, regulation, and role in disease. J. Mol. Med. 80:753-769.
-
(2002)
J. Mol. Med
, vol.80
, pp. 753-769
-
-
Mead, J.R.1
Irvine, S.A.2
Ramji, D.P.3
-
4
-
-
34447511196
-
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
-
Nordestgaard, B.G., Benn, M., Schnohr, P., and Tybjaerg-Hansen, A. 2007. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA. 298:299-308.
-
(2007)
JAMA
, vol.298
, pp. 299-308
-
-
Nordestgaard, B.G.1
Benn, M.2
Schnohr, P.3
Tybjaerg-Hansen, A.4
-
5
-
-
0037200065
-
Identification of the proteoglycan binding site in apolipoprotein B48
-
Flood, C., et al. 2002. Identification of the proteoglycan binding site in apolipoprotein B48. J. Biol. Chem. 277:32228-32233.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 32228-32233
-
-
Flood, C.1
-
6
-
-
0029299438
-
The response-toretention hypothesis of early atherogenesis
-
Williams, K.J., and Tabas, I. 1995. The response-toretention hypothesis of early atherogenesis. Arterioscler. Thromb. Vasc. Biol. 15:551-561.
-
(1995)
Arterioscler. Thromb. Vasc. Biol
, vol.15
, pp. 551-561
-
-
Williams, K.J.1
Tabas, I.2
-
7
-
-
0029005963
-
Postprandial lipoprotein metabolism and atherosclerosis
-
Karpe, F., and Hamsten, A. 1995. Postprandial lipoprotein metabolism and atherosclerosis. Curr. Opin. Lipidol. 6:123-129.
-
(1995)
Curr. Opin. Lipidol
, vol.6
, pp. 123-129
-
-
Karpe, F.1
Hamsten, A.2
-
8
-
-
46249093117
-
Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome
-
Adiels, M., Olofsson, S.-O., Taskinen, M.-R., and Borén, J. 2008. Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome. Arterioscler. Thromb. Vasc. Biol. 28:1225-1236.
-
(2008)
Arterioscler. Thromb. Vasc. Biol
, vol.28
, pp. 1225-1236
-
-
Adiels, M.1
Olofsson, S.-O.2
Taskinen, M.-R.3
Borén, J.4
-
9
-
-
0037071843
-
Subendothelial retention of atherogenic lipoproteins in early atherosclerosis
-
Skålén, K., et al. 2002. Subendothelial retention of atherogenic lipoproteins in early atherosclerosis. Nature. 417:750-754.
-
(2002)
Nature
, vol.417
, pp. 750-754
-
-
Skålén, K.1
-
10
-
-
34247393620
-
Early human atherosclerosis: Accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration
-
Nakashima, Y., Fujii, H., Sumiyoshi, S., Wight, T.N., and Sueishi, K. 2007. Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration. Arterioscler. Thromb. Vasc. Biol. 27:1159-1165.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 1159-1165
-
-
Nakashima, Y.1
Fujii, H.2
Sumiyoshi, S.3
Wight, T.N.4
Sueishi, K.5
-
11
-
-
37349021003
-
Subendothelial lipoprotein retention as the initiating process in atherosclerosis: Update and therapeutic implications
-
Tabas, I., Williams, K.J., and Borén, J. 2007. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation. 116:1832-1844.
-
(2007)
Circulation
, vol.116
, pp. 1832-1844
-
-
Tabas, I.1
Williams, K.J.2
Borén, J.3
-
12
-
-
38649110177
-
Rapid regression of atherosclerosis: Insights from the clinical and experimental literature
-
Williams, K.J., Feig, J.E., and Fisher, E.A. 2008. Rapid regression of atherosclerosis: insights from the clinical and experimental literature. Nat. Clin. Pract. Cardiovasc. Med. 5:91-102.
-
(2008)
Nat. Clin. Pract. Cardiovasc. Med
, vol.5
, pp. 91-102
-
-
Williams, K.J.1
Feig, J.E.2
Fisher, E.A.3
-
13
-
-
34447520136
-
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
-
Bansal, S., et al. 2007. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA. 298:309-316.
-
(2007)
JAMA
, vol.298
, pp. 309-316
-
-
Bansal, S.1
-
14
-
-
33644878249
-
Cardiovascular disease in the developing world and its cost-effective management
-
Gaziano, T.A. 2005. Cardiovascular disease in the developing world and its cost-effective management. Circulation. 112:3547-3553.
-
(2005)
Circulation
, vol.112
, pp. 3547-3553
-
-
Gaziano, T.A.1
-
15
-
-
33745310797
-
Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: Evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine
-
Federico, L.M., Naples, M., Taylor, D., and Adeli, K. 2006. Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine. Diabetes. 55:1316-1326.
-
(2006)
Diabetes
, vol.55
, pp. 1316-1326
-
-
Federico, L.M.1
Naples, M.2
Taylor, D.3
Adeli, K.4
-
16
-
-
0346731237
-
The discovery of ezetimibe: A view from outside the receptor
-
Clader, J.W. 2004. The discovery of ezetimibe: a view from outside the receptor. J. Med. Chem. 47:1-9.
-
(2004)
J. Med. Chem
, vol.47
, pp. 1-9
-
-
Clader, J.W.1
-
17
-
-
20444371945
-
The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
-
Garcia-Calvo, M., et al. 2005. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc. Natl. Acad. Sci. U. S. A. 102:8132-8137.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 8132-8137
-
-
Garcia-Calvo, M.1
-
18
-
-
33750219268
-
NPC1L1: Evolution from pharmacological target to physiological sterol transporter
-
Huff, M.W., Pollex, R.L., and Hegele, R.A. 2006. NPC1L1: Evolution from pharmacological target to physiological sterol transporter. Arterioscler. Thromb. Vasc. Biol. 26:2433-2438.
-
(2006)
Arterioscler. Thromb. Vasc. Biol
, vol.26
, pp. 2433-2438
-
-
Huff, M.W.1
Pollex, R.L.2
Hegele, R.A.3
-
19
-
-
10744221008
-
Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption
-
Altmann, S.W., et al. 2004. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science. 303:1201-1204.
-
(2004)
Science
, vol.303
, pp. 1201-1204
-
-
Altmann, S.W.1
-
20
-
-
16844376244
-
Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia
-
Davies, J.P., Scott, C., Oishi, K., Liapis, A., and Ioannou, Y.A. 2005. Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia. J. Biol. Chem. 280:12710-12720.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 12710-12720
-
-
Davies, J.P.1
Scott, C.2
Oishi, K.3
Liapis, A.4
Ioannou, Y.A.5
-
21
-
-
46249103255
-
Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes
-
Fahmi, S., Yang, C., Esmail, S., Hobbs, H.H., and Cohen, J.C. 2008. Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes. Hum. Mol. Genet. 17:2101-2107.
-
(2008)
Hum. Mol. Genet
, vol.17
, pp. 2101-2107
-
-
Fahmi, S.1
Yang, C.2
Esmail, S.3
Hobbs, H.H.4
Cohen, J.C.5
-
22
-
-
33646564118
-
Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake
-
Yu, L., et al. 2006. Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake. J. Biol. Chem. 281:6616-6624.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 6616-6624
-
-
Yu, L.1
-
23
-
-
34548644843
-
Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane
-
Knopfel, M., et al. 2007. Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane. Biochim. Biophys. Acta. 1771:1140-1147.
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 1140-1147
-
-
Knopfel, M.1
-
24
-
-
34548182369
-
Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells
-
Field, F.J., Watt, K., and Mathur, S.N. 2007. Ezetimibe interferes with cholesterol trafficking from the plasma membrane to the endoplasmic reticulum in CaCo-2 cells. J. Lipid Res. 48:1735-1745.
-
(2007)
J. Lipid Res
, vol.48
, pp. 1735-1745
-
-
Field, F.J.1
Watt, K.2
Mathur, S.N.3
-
25
-
-
34447120058
-
Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe
-
Temel, R.E., et al. 2007. Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe. J. Clin. Invest. 117:1968-1978.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 1968-1978
-
-
Temel, R.E.1
-
26
-
-
55849141276
-
Inhibition of cholesterol absorption with ezetimibe promotes macrophage to feces reverse cholesterol transport in mice [abstract]
-
159-II-160
-
Briand, F., Millar, J., Billheimer, J., Rothblat, G., and Rader, D. 2007. Inhibition of cholesterol absorption with ezetimibe promotes macrophage to feces reverse cholesterol transport in mice [abstract]. Circulation. II-159-II-160.
-
(2007)
Circulation
, vol.2
-
-
Briand, F.1
Millar, J.2
Billheimer, J.3
Rothblat, G.4
Rader, D.5
-
27
-
-
46249110108
-
Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages
-
Sehayek, E., and Hazen, S.L. 2008. Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages. Arterioscler. Thromb. Vasc. Biol. 28:1296-1297.
-
(2008)
Arterioscler. Thromb. Vasc. Biol
, vol.28
, pp. 1296-1297
-
-
Sehayek, E.1
Hazen, S.L.2
-
28
-
-
33846829068
-
Genes that affect cholesterol synthesis, cholesterol absorption, and chylomicron assembly: The relationship between the liver and intestine in control and streptozotosin diabetic rats
-
Lally, S., Owens, D., and Tomkin, G.H. 2007. Genes that affect cholesterol synthesis, cholesterol absorption, and chylomicron assembly: the relationship between the liver and intestine in control and streptozotosin diabetic rats. Metabolism. 56:430-438.
-
(2007)
Metabolism
, vol.56
, pp. 430-438
-
-
Lally, S.1
Owens, D.2
Tomkin, G.H.3
-
29
-
-
34447623211
-
Markers of absorption and synthesis of cholesterol in men with type 1 diabetes
-
Gylling, H., et al. 2007. Markers of absorption and synthesis of cholesterol in men with type 1 diabetes. Diabetes Metab. Res. Rev. 23:372-377.
-
(2007)
Diabetes Metab. Res. Rev
, vol.23
, pp. 372-377
-
-
Gylling, H.1
-
30
-
-
33646412333
-
Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: The role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein
-
Lally, S., Tan, C.Y., Owens, D., and Tomkin, G.H. 2006. Messenger RNA levels of genes involved in dysregulation of postprandial lipoproteins in type 2 diabetes: the role of Niemann-Pick C1-like 1, ATP-binding cassette, transporters G5 and G8, and of microsomal triglyceride transfer protein. Diabetologia. 49:1008-1016.
-
(2006)
Diabetologia
, vol.49
, pp. 1008-1016
-
-
Lally, S.1
Tan, C.Y.2
Owens, D.3
Tomkin, G.H.4
-
31
-
-
0030601714
-
Cholesterol absorption and lipoprotein metabolism in type II diabetes mellitus with and without coronary artery disease
-
Gylling, H., and Miettinen, T.A. 1996. Cholesterol absorption and lipoprotein metabolism in type II diabetes mellitus with and without coronary artery disease. Atherosclerosis. 126:325-332.
-
(1996)
Atherosclerosis
, vol.126
, pp. 325-332
-
-
Gylling, H.1
Miettinen, T.A.2
-
32
-
-
34247209263
-
Deficiency of Niemann-Pick C1 like 1 prevents atherosclerosis in apoE-/-mice
-
Davis, H.R., Jr., et al. 2007. Deficiency of Niemann-Pick C1 like 1 prevents atherosclerosis in apoE-/-mice. Arterioscler. Thromb. Vasc. Biol. 27:841-849.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 841-849
-
-
Davis Jr., H.R.1
-
33
-
-
41649107358
-
Simvastatin with or without ezetimibe in familial hypercholesterolemia
-
Kastelein, J.J., et al. 2008. Simvastatin with or without ezetimibe in familial hypercholesterolemia. N. Engl. J. Med. 358:1431-1443.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 1431-1443
-
-
Kastelein, J.J.1
-
34
-
-
0037058995
-
Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
-
Yu, L., et al. 2002. Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion. Proc. Natl. Acad. Sci. U. S. A. 99:16237-16242.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A
, vol.99
, pp. 16237-16242
-
-
Yu, L.1
-
35
-
-
0348111456
-
ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion
-
Graf, G.A., et al. 2003. ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. J. Biol. Chem. 278:48275-48282.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 48275-48282
-
-
Graf, G.A.1
-
36
-
-
0038614979
-
Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8
-
Yu, L., et al. 2003. Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8. J. Biol. Chem. 278:15565-15570.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 15565-15570
-
-
Yu, L.1
-
37
-
-
0030866533
-
Normal intestinal dietary fat and cholesterol absorption, intestinal apolipoprotein B (apoB) mRNA levels, and apoB-48 synthesis in a hypobetalipoproteinemic kindred without any apoB truncation
-
Pulai, J.I., et al. 1997. Normal intestinal dietary fat and cholesterol absorption, intestinal apolipoprotein B (apoB) mRNA levels, and apoB-48 synthesis in a hypobetalipoproteinemic kindred without any apoB truncation. Metabolism. 46:1095-1100.
-
(1997)
Metabolism
, vol.46
, pp. 1095-1100
-
-
Pulai, J.I.1
-
38
-
-
0016816559
-
The mechanims of assimilation of consitutents of chylomicrons, very low density lipoproteins and remnants - a new theory
-
Felts, J.M., Itakura, H., and Crane, R.T. 1975. The mechanims of assimilation of consitutents of chylomicrons, very low density lipoproteins and remnants - a new theory. Biochem. Biophys. Res. Commun. 66:1467-1475.
-
(1975)
Biochem. Biophys. Res. Commun
, vol.66
, pp. 1467-1475
-
-
Felts, J.M.1
Itakura, H.2
Crane, R.T.3
-
39
-
-
0026717599
-
Mechanisms by which lipoprotein lipase alters cellular metabolism of lipoprotein(a), low density lipoprotein, and nascent lipoproteins. Roles for low density lipoprotein receptors and heparan sulfate proteoglycans
-
Williams, K.J., et al. 1992. Mechanisms by which lipoprotein lipase alters cellular metabolism of lipoprotein(a), low density lipoprotein, and nascent lipoproteins. Roles for low density lipoprotein receptors and heparan sulfate proteoglycans. J. Biol. Chem. 267:13284-13292.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 13284-13292
-
-
Williams, K.J.1
-
40
-
-
0030803636
-
The syndecan family of proteoglycans: Novel receptors mediating internalization of atherogenic lipoproteins in vitro
-
Fuki, I.V., et al. 1997. The syndecan family of proteoglycans: novel receptors mediating internalization of atherogenic lipoproteins in vitro. J. Clin. Invest. 100:1611-1622.
-
(1997)
J. Clin. Invest
, vol.100
, pp. 1611-1622
-
-
Fuki, I.V.1
-
41
-
-
33646689532
-
Lipoprotein lipase bound to apolipoprotein B lipoproteins accelerates clearance of postprandial lipoproteins in humans
-
Zheng, C., Murdoch, S.J., Brunzell, J.D., and Sacks, F.M. 2006. Lipoprotein lipase bound to apolipoprotein B lipoproteins accelerates clearance of postprandial lipoproteins in humans. Arterioscler. Thromb. Vasc. Biol. 26:891-896.
-
(2006)
Arterioscler. Thromb. Vasc. Biol
, vol.26
, pp. 891-896
-
-
Zheng, C.1
Murdoch, S.J.2
Brunzell, J.D.3
Sacks, F.M.4
-
42
-
-
0034522037
-
In vivo evidence of a role for hepatic lipase in human apoB-containing lipoprotein metabolism, independent of its lipolytic activity
-
Zambon, A., Deeb, S.S., Bensadoun, A., Foster, K.E., and Brunzell, J.D. 2000. In vivo evidence of a role for hepatic lipase in human apoB-containing lipoprotein metabolism, independent of its lipolytic activity. J. Lipid Res. 41:2094-2099.
-
(2000)
J. Lipid Res
, vol.41
, pp. 2094-2099
-
-
Zambon, A.1
Deeb, S.S.2
Bensadoun, A.3
Foster, K.E.4
Brunzell, J.D.5
-
43
-
-
33645530765
-
Postprandial lipoprotein metabolism, genes and risk of cardiovascular disease
-
López-Miranda, J., et al. 2006. Postprandial lipoprotein metabolism, genes and risk of cardiovascular disease. Curr. Opin. Lipidol. 17:132-138.
-
(2006)
Curr. Opin. Lipidol
, vol.17
, pp. 132-138
-
-
López-Miranda, J.1
-
44
-
-
0028339789
-
Variable heparan sulfate proteoglycan binding of apolipoprotein E variants may modulate the expression of type III hyperlipoproteinemia
-
Ji, Z.S., Fazio, S., and Mahley, R.W. 1994. Variable heparan sulfate proteoglycan binding of apolipoprotein E variants may modulate the expression of type III hyperlipoproteinemia. J. Biol. Chem. 269:13421-13428.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 13421-13428
-
-
Ji, Z.S.1
Fazio, S.2
Mahley, R.W.3
-
45
-
-
0028939751
-
Apolipoprotein E isoforms and rare mutations: Parallel reduction in binding to cells and to heparin reflects severity of associated type III hyperlipoproteinemia
-
Mann, W.A., et al. 1995. Apolipoprotein E isoforms and rare mutations: parallel reduction in binding to cells and to heparin reflects severity of associated type III hyperlipoproteinemia. J. Lipid Res. 36:517-525.
-
(1995)
J. Lipid Res
, vol.36
, pp. 517-525
-
-
Mann, W.A.1
-
46
-
-
0028827449
-
Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway
-
Mortimer, B.C., Beveridge, D.J., Martins, I.J., and Redgrave, T.G. 1995. Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway. J. Biol. Chem. 270:28767-28776.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 28767-28776
-
-
Mortimer, B.C.1
Beveridge, D.J.2
Martins, I.J.3
Redgrave, T.G.4
-
47
-
-
38649110731
-
A treasure trove for lipoprotein biology
-
Lusis, A.J., and Pajukanta, P. 2008. A treasure trove for lipoprotein biology. Nat. Genet. 40:129-130.
-
(2008)
Nat. Genet
, vol.40
, pp. 129-130
-
-
Lusis, A.J.1
Pajukanta, P.2
-
48
-
-
38349186574
-
Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation?
-
Lo, C.M., et al. 2008. Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation? Am. J. Physiol. 294:G344-G352.
-
(2008)
Am. J. Physiol
, vol.294
-
-
Lo, C.M.1
-
49
-
-
0037124084
-
Complexity in the secretory pathway: The assembly and secretion of apolipoprotein B-containing lipoproteins
-
Fisher, E.A., and Ginsberg, H.N. 2002. Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins. J. Biol. Chem. 277:17377-17380.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 17377-17380
-
-
Fisher, E.A.1
Ginsberg, H.N.2
-
50
-
-
0035958917
-
The triple threat to nascent apolipoprotein-B: Evidence for multiple, distinct degradative pathways
-
Fisher, E.A., et al. 2001. The triple threat to nascent apolipoprotein-B: evidence for multiple, distinct degradative pathways. J. Biol. Chem. 276:27855-27863.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 27855-27863
-
-
Fisher, E.A.1
-
51
-
-
0035930622
-
Direct evidence for a two-step assembly of apoB48-containing lipoproteins in the lumen of the smooth endoplasmic reticulum of rabbit enterocytes
-
Cartwright, I.J., and Higgins, J.A. 2001. Direct evidence for a two-step assembly of apoB48-containing lipoproteins in the lumen of the smooth endoplasmic reticulum of rabbit enterocytes. J. Biol. Chem. 276:48048-48057.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 48048-48057
-
-
Cartwright, I.J.1
Higgins, J.A.2
-
52
-
-
0346220266
-
Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER
-
Gusarova, V., Brodsky, J.L., and Fisher, E.A. 2003. Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER. J. Biol. Chem. 278:48051-48058.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 48051-48058
-
-
Gusarova, V.1
Brodsky, J.L.2
Fisher, E.A.3
-
53
-
-
11244315379
-
Relation of the size and intracellular sorting of apoB to the formation of VLDL1 and VLDL2
-
Stillemark-Billton, P., Beck, C., Borén, J., and Olofsson, S.O. 2005. Relation of the size and intracellular sorting of apoB to the formation of VLDL1 and VLDL2. J. Lipid Res. 46:104-114.
-
(2005)
J. Lipid Res
, vol.46
, pp. 104-114
-
-
Stillemark-Billton, P.1
Beck, C.2
Borén, J.3
Olofsson, S.O.4
-
54
-
-
0034635552
-
Apolipoprotein B, a paradigm for proteins regulated by intracellular degradation, does not undergo intracellular degradation in CaCo2 cells
-
Liao, W., and Chan, L. 2000. Apolipoprotein B, a paradigm for proteins regulated by intracellular degradation, does not undergo intracellular degradation in CaCo2 cells. J. Biol. Chem. 275:3950-3956.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 3950-3956
-
-
Liao, W.1
Chan, L.2
-
55
-
-
0026470990
-
Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia
-
Wetterau, J.R., et al. 1992. Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. Science. 258:999-1001.
-
(1992)
Science
, vol.258
, pp. 999-1001
-
-
Wetterau, J.R.1
-
56
-
-
33846151732
-
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia
-
Cuchel, M., et al. 2007. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. N. Engl. J. Med. 356:148-156.
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 148-156
-
-
Cuchel, M.1
-
57
-
-
20744453153
-
Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants
-
Jiang, X.C., et al. 2005. Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants. J. Biol. Chem. 280:18336-18340.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 18336-18340
-
-
Jiang, X.C.1
-
58
-
-
34548312474
-
Diurnal regulation of microsomal triglyceride transfer protein and plasma lipid levels
-
Pan, X., and Hussain, M.M. 2007. Diurnal regulation of microsomal triglyceride transfer protein and plasma lipid levels. J. Biol. Chem. 34:24707-24719.
-
(2007)
J. Biol. Chem
, vol.34
, pp. 24707-24719
-
-
Pan, X.1
Hussain, M.M.2
-
59
-
-
44449090993
-
Pre-secretory oxidation, aggregation, and autophagic destruction of apolipoprotein-B: A pathway for late-stage quality control
-
Pan, M., et al. 2008. Pre-secretory oxidation, aggregation, and autophagic destruction of apolipoprotein-B: a pathway for late-stage quality control. Proc. Natl. Acad. Sci. U. S. A. 105:5862-5867.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A
, vol.105
, pp. 5862-5867
-
-
Pan, M.1
-
60
-
-
0025064543
-
The unstirred water layer as a site of control of apolipoprotein B secretion
-
Williams, K.J., Brocia, R.W., and Fisher, E.A. 1990. The unstirred water layer as a site of control of apolipoprotein B secretion. J. Biol. Chem. 265:16741-16744.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 16741-16744
-
-
Williams, K.J.1
Brocia, R.W.2
Fisher, E.A.3
-
61
-
-
0027233887
-
Fish oil reduces postprandial triglyceride concentrations without accelerating lipid-emulsion removal rates
-
Harris, W.S., and Muzio, F. 1993. Fish oil reduces postprandial triglyceride concentrations without accelerating lipid-emulsion removal rates. Am. J. Clin. Nutr. 58:68-74.
-
(1993)
Am. J. Clin. Nutr
, vol.58
, pp. 68-74
-
-
Harris, W.S.1
Muzio, F.2
-
62
-
-
0023732825
-
Intracellular apoA-I and apoB distribution in rat intestine is altered by lipid feeding
-
Magun, A.M., Mish, B., and Glickman, R.M. 1988. Intracellular apoA-I and apoB distribution in rat intestine is altered by lipid feeding. J. Lipid Res. 29:1107-1116.
-
(1988)
J. Lipid Res
, vol.29
, pp. 1107-1116
-
-
Magun, A.M.1
Mish, B.2
Glickman, R.M.3
-
63
-
-
0035097314
-
Effect of the apolipoprotein A-IV Q360H polymorphism on postprandial plasma triglyceride clearance
-
Hockey, K.J., Anderson, R.A., Cook, V.R., Hantgan, R.R., and Weinberg, R.B. 2001. Effect of the apolipoprotein A-IV Q360H polymorphism on postprandial plasma triglyceride clearance. J. Lipid Res. 42:211-217.
-
(2001)
J. Lipid Res
, vol.42
, pp. 211-217
-
-
Hockey, K.J.1
Anderson, R.A.2
Cook, V.R.3
Hantgan, R.R.4
Weinberg, R.B.5
-
64
-
-
34547114033
-
Liver fatty acid-binding protein initiates budding of pre-chylomicron transport vesicles from intestinal endoplasmic reticulum
-
Neeli, I., et al. 2007. Liver fatty acid-binding protein initiates budding of pre-chylomicron transport vesicles from intestinal endoplasmic reticulum. J. Biol. Chem. 282:17974-17984.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 17974-17984
-
-
Neeli, I.1
-
65
-
-
0037656344
-
Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders
-
Jones, B., et al. 2003. Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders. Nat. Genet. 34:29-31.
-
(2003)
Nat. Genet
, vol.34
, pp. 29-31
-
-
Jones, B.1
-
66
-
-
37049038447
-
Anderson or chylomicron retention disease: Molecular impact of five mutations in the SAR1B gene on the structure and the functionality of Sar1b protein
-
Charcosset, M., et al. 2008. Anderson or chylomicron retention disease: Molecular impact of five mutations in the SAR1B gene on the structure and the functionality of Sar1b protein. Mol. Genet. Metab. 93:74-84.
-
(2008)
Mol. Genet. Metab
, vol.93
, pp. 74-84
-
-
Charcosset, M.1
-
67
-
-
34548155292
-
Evidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes
-
Hogue, J.C., et al. 2007. Evidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes. J. Lipid Res. 48:1336-1342.
-
(2007)
J. Lipid Res
, vol.48
, pp. 1336-1342
-
-
Hogue, J.C.1
-
68
-
-
20544456374
-
Evidence for multiple complementary pathways for efficient cholesterol absorption in mice
-
Iqbal, J., and Hussain, M.M. 2005. Evidence for multiple complementary pathways for efficient cholesterol absorption in mice. J. Lipid Res. 46:1491-1501.
-
(2005)
J. Lipid Res
, vol.46
, pp. 1491-1501
-
-
Iqbal, J.1
Hussain, M.M.2
-
69
-
-
27444432557
-
Intestinal cholesterol absorption is substantially reduced in mice deficient in both ABCA1 and ACAT2
-
Temel, R.E., et al. 2005. Intestinal cholesterol absorption is substantially reduced in mice deficient in both ABCA1 and ACAT2. J. Lipid Res. 46:2423-2431.
-
(2005)
J. Lipid Res
, vol.46
, pp. 2423-2431
-
-
Temel, R.E.1
-
70
-
-
0029836411
-
Effects of lipid administration on lymphatic apolipoprotein A-IV and B output and synthesis
-
Nishimura, M., Seishima, M., Ohashi, H., and Noma, A. 1996. Effects of lipid administration on lymphatic apolipoprotein A-IV and B output and synthesis. Am. J. Physiol. 271:G322-G329.
-
(1996)
Am. J. Physiol
, vol.271
-
-
Nishimura, M.1
Seishima, M.2
Ohashi, H.3
Noma, A.4
-
71
-
-
34548572892
-
Bile acid transporters: Structure, function, regulation and pathophysiological implications
-
Alrefai, W.A., and Gill, R.K. 2007. Bile acid transporters: structure, function, regulation and pathophysiological implications. Pharm. Res. 24:1803-1823.
-
(2007)
Pharm. Res
, vol.24
, pp. 1803-1823
-
-
Alrefai, W.A.1
Gill, R.K.2
-
72
-
-
55849112223
-
-
Olivecrona, T., and Bengtsson-Olivecrona, G. 1987. Lipoprotein lipase from milk - the model enzyme in lipoprotein lipase research. In Lipoprotein lipase. J. Borensztajn, editor. Evener. Chicago, Illinois, USA. 15-58.
-
Olivecrona, T., and Bengtsson-Olivecrona, G. 1987. Lipoprotein lipase from milk - the model enzyme in lipoprotein lipase research. In Lipoprotein lipase. J. Borensztajn, editor. Evener. Chicago, Illinois, USA. 15-58.
-
-
-
-
73
-
-
0026580349
-
Structure and functional properties of lipoprotein lipase
-
Wang, C.-S., Hartsuck, J., and McConathy, W.J. 1992. Structure and functional properties of lipoprotein lipase. Biochim. Biophys. Acta. 1123:1-17.
-
(1992)
Biochim. Biophys. Acta
, vol.1123
, pp. 1-17
-
-
Wang, C.-S.1
Hartsuck, J.2
McConathy, W.J.3
-
74
-
-
0030775796
-
Cell-surface heparan sulfate proteoglycans: Dynamic molecules mediating ligand catabolism
-
Williams, K.J., and Fuki, I.V. 1997. Cell-surface heparan sulfate proteoglycans: dynamic molecules mediating ligand catabolism. Curr. Opin. Lipidol. 8:253-262.
-
(1997)
Curr. Opin. Lipidol
, vol.8
, pp. 253-262
-
-
Williams, K.J.1
Fuki, I.V.2
-
75
-
-
36048975597
-
Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650)
-
Wang, J., et al. 2007. Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650). Arterioscler. Thromb. Vasc. Biol. 27:2450-2455.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 2450-2455
-
-
Wang, J.1
-
76
-
-
0035937846
-
Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor
-
Obunike, J.C., et al. 2001. Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor. J. Biol. Chem. 276:8934-8941.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 8934-8941
-
-
Obunike, J.C.1
-
77
-
-
0030853681
-
Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase
-
Jensen, D.R., et al. 1997. Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase. Am. J. Physiol. 273:R683-R689.
-
(1997)
Am. J. Physiol
, vol.273
-
-
Jensen, D.R.1
-
78
-
-
0024383973
-
Lipoprotein lipase in myocytes and capillary endothelium of heart: Immunocytochemical study
-
Blanchette-Mackie, E.J., Masuno, H., Dwyer, N.K., Olivecrona, T., and Scow, R.O. 1989. Lipoprotein lipase in myocytes and capillary endothelium of heart: immunocytochemical study. Am. J. Physiol. 256:E818-E828.
-
(1989)
Am. J. Physiol
, vol.256
-
-
Blanchette-Mackie, E.J.1
Masuno, H.2
Dwyer, N.K.3
Olivecrona, T.4
Scow, R.O.5
-
79
-
-
35748941921
-
Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease
-
Hamilton, M.T., Hamilton, D.G., and Zderic, T.W. 2007. Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease. Diabetes. 56:2655-2667.
-
(2007)
Diabetes
, vol.56
, pp. 2655-2667
-
-
Hamilton, M.T.1
Hamilton, D.G.2
Zderic, T.W.3
-
80
-
-
33646708939
-
Non-exercise activity thermogenesis: The Crouching Tiger Hidden Dragon of societal weight gain
-
Levine, J.A., Vander Weg, M.W., Hill, J.O., and Klesges, R.C. 2006. Non-exercise activity thermogenesis: the Crouching Tiger Hidden Dragon of societal weight gain. Arterioscler. Thromb. Vasc. Biol. 26:729-736.
-
(2006)
Arterioscler. Thromb. Vasc. Biol
, vol.26
, pp. 729-736
-
-
Levine, J.A.1
Vander Weg, M.W.2
Hill, J.O.3
Klesges, R.C.4
-
81
-
-
34547657857
-
The real contribution of added sugars and fats to obesity
-
Drewnowski, A. 2007. The real contribution of added sugars and fats to obesity. Epidemiol. Rev. 29:160-171.
-
(2007)
Epidemiol. Rev
, vol.29
, pp. 160-171
-
-
Drewnowski, A.1
-
82
-
-
36549038120
-
Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia
-
Péterfy, M., et al. 2007. Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat. Genet. 39:1483-1487.
-
(2007)
Nat. Genet
, vol.39
, pp. 1483-1487
-
-
Péterfy, M.1
-
83
-
-
0024534976
-
Secretion and degradation of lipoprotein lipase in cultured adipocytes. Binding of lipoprotein lipase to membrane heparan sulfate proteoglycans is necessary for degradation
-
Cisar, L.A., Hoogewerf, A.J., Cupp, M., Rapport, C.A., and Bensadoun, A. 1989. Secretion and degradation of lipoprotein lipase in cultured adipocytes. Binding of lipoprotein lipase to membrane heparan sulfate proteoglycans is necessary for degradation. J. Biol. Chem. 264:1767-1774.
-
(1989)
J. Biol. Chem
, vol.264
, pp. 1767-1774
-
-
Cisar, L.A.1
Hoogewerf, A.J.2
Cupp, M.3
Rapport, C.A.4
Bensadoun, A.5
-
84
-
-
33751213896
-
Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue
-
Sukonina, V., Lookene, A., Olivecrona, T., and Olivecrona, G. 2006. Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. Proc. Natl. Acad. Sci. U. S. A. 103:17450-17455.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 17450-17455
-
-
Sukonina, V.1
Lookene, A.2
Olivecrona, T.3
Olivecrona, G.4
-
85
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
Backhed, F., et al. 2004. The gut microbiota as an environmental factor that regulates fat storage. Proc. Natl. Acad. Sci. U. S. A. 101:15718-15723.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 15718-15723
-
-
Backhed, F.1
-
86
-
-
38949161524
-
Determinants of intramyocellular triglyceride turnover: Implications for insulin sensitivity
-
Moro, C., Bajpeyi, S., and Smith, S.R. 2008. Determinants of intramyocellular triglyceride turnover: Implications for insulin sensitivity. Am. J. Physiol. 294:E203-E213.
-
(2008)
Am. J. Physiol
, vol.294
-
-
Moro, C.1
Bajpeyi, S.2
Smith, S.R.3
-
87
-
-
0035912744
-
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
-
Kim, J.K., et al. 2001. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc. Natl. Acad. Sci. U. S. A. 98:7522-7527.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A
, vol.98
, pp. 7522-7527
-
-
Kim, J.K.1
-
88
-
-
0042160182
-
The role of intramuscular lipid in insulin resistance
-
Hegarty, B.D., Furler, S.M., Ye, J., Cooney, G.J., and Kraegen, E.W. 2003. The role of intramuscular lipid in insulin resistance. Acta Physiol. Scand. 178:373-383.
-
(2003)
Acta Physiol. Scand
, vol.178
, pp. 373-383
-
-
Hegarty, B.D.1
Furler, S.M.2
Ye, J.3
Cooney, G.J.4
Kraegen, E.W.5
-
89
-
-
0028346379
-
Liver heparan sulfate structure. A novel molecular design
-
Lyon, M., Deakin, J.A., and Gallagher, J.T. 1994. Liver heparan sulfate structure. A novel molecular design. J. Biol. Chem. 269:11208- 11215.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 11208-11215
-
-
Lyon, M.1
Deakin, J.A.2
Gallagher, J.T.3
-
90
-
-
33947573537
-
Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons
-
Beigneux, A.P., et al. 2007. Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab. 5:279-291.
-
(2007)
Cell Metab
, vol.5
, pp. 279-291
-
-
Beigneux, A.P.1
-
91
-
-
36049022385
-
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice
-
Hofmann, S.M., et al. 2007. Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J. Clin. Invest. 117:3271-3282.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 3271-3282
-
-
Hofmann, S.M.1
-
92
-
-
0035812707
-
An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing
-
Pennacchio, L.A., et al. 2001. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science. 294:169-173.
-
(2001)
Science
, vol.294
, pp. 169-173
-
-
Pennacchio, L.A.1
-
93
-
-
26444617632
-
Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment
-
Marcais, C., et al. 2005. Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment. J. Clin. Invest. 115:2862-2869.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 2862-2869
-
-
Marcais, C.1
-
94
-
-
20144375048
-
Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase
-
Merkel, M., et al. 2005. Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase. J. Biol. Chem. 280:21553-21560.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 21553-21560
-
-
Merkel, M.1
-
95
-
-
34447314745
-
GPIHBP1: An endothelial cell molecule important for the lipolytic processing of chylomicrons
-
Young, S.G., et al. 2007. GPIHBP1: an endothelial cell molecule important for the lipolytic processing of chylomicrons. Curr. Opin. Lipidol. 18:389-396.
-
(2007)
Curr. Opin. Lipidol
, vol.18
, pp. 389-396
-
-
Young, S.G.1
-
96
-
-
0037470185
-
Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1
-
Ioka, R.X., et al. 2003. Expression cloning and characterization of a novel glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein, GPI-HBP1. J. Biol. Chem. 278:7344-7349.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 7344-7349
-
-
Ioka, R.X.1
-
97
-
-
0037040994
-
Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities
-
Razani, B., et al. 2002. Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities. J. Biol. Chem. 277:8635-8647.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 8635-8647
-
-
Razani, B.1
-
98
-
-
38349059093
-
Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution
-
Gin, P., et al. 2007. Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution. Biochim. Biophys. Acta. 1771:1464-1468.
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 1464-1468
-
-
Gin, P.1
-
99
-
-
0034331817
-
Transmembrane and cytoplasmic domains of syndecan mediate a multi-step endocytic pathway involving detergent-insoluble membrane rafts
-
Fuki, I.V., Meyer, M.E., and Williams, K.J. 2000. Transmembrane and cytoplasmic domains of syndecan mediate a multi-step endocytic pathway involving detergent-insoluble membrane rafts. Biochem. J. 351:607-612.
-
(2000)
Biochem. J
, vol.351
, pp. 607-612
-
-
Fuki, I.V.1
Meyer, M.E.2
Williams, K.J.3
-
100
-
-
4344682721
-
Fibroblast growth factor 2 endocytosis in endothelial cells proceed via syndecan-4-dependent activation of Rac1 and a Cdc42-dependent macropinocytic pathway
-
Tkachenko, E., Lutgens, E., Stan, R.V., and Simons, M. 2004. Fibroblast growth factor 2 endocytosis in endothelial cells proceed via syndecan-4-dependent activation of Rac1 and a Cdc42-dependent macropinocytic pathway. J. Cell Sci. 117:3189-3199.
-
(2004)
J. Cell Sci
, vol.117
, pp. 3189-3199
-
-
Tkachenko, E.1
Lutgens, E.2
Stan, R.V.3
Simons, M.4
-
101
-
-
0028000605
-
Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking
-
Mayor, S., Rothberg, K.G., and Maxfield, F.R. 1994. Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science. 264:1948-1951.
-
(1994)
Science
, vol.264
, pp. 1948-1951
-
-
Mayor, S.1
Rothberg, K.G.2
Maxfield, F.R.3
-
102
-
-
0030855789
-
Regulation of FAT/CD36 gene expression: Further evidence in support of a role of the protein in fatty acid binding/transport
-
Sfeir, Z., Ibrahimi, A., Amri, E., Grimaldi, P., and Abumrad, N. 1997. Regulation of FAT/CD36 gene expression: further evidence in support of a role of the protein in fatty acid binding/transport. Prostaglandins Leukot. Essent. Fatty Acids. 57:17-21.
-
(1997)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.57
, pp. 17-21
-
-
Sfeir, Z.1
Ibrahimi, A.2
Amri, E.3
Grimaldi, P.4
Abumrad, N.5
-
103
-
-
33744454918
-
The fatty acid transporter FAT/CD36 is upregulated in subcutaneous and visceral adipose tissues in human obesity and type 2 diabetes
-
Bonen, A., Tandon, N.N., Glatz, J.F., Luiken, J.J., and Heigenhauser, G.J. 2006. The fatty acid transporter FAT/CD36 is upregulated in subcutaneous and visceral adipose tissues in human obesity and type 2 diabetes. Int. J. Obes. (Lond.) 30:877-883.
-
(2006)
Int. J. Obes. (Lond.)
, vol.30
, pp. 877-883
-
-
Bonen, A.1
Tandon, N.N.2
Glatz, J.F.3
Luiken, J.J.4
Heigenhauser, G.J.5
-
104
-
-
11144325698
-
FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts
-
Pohl, J., Ring, A., Korkmaz, U., Ehehalt, R., and Stremmel, W. 2005. FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts. Mol. Biol. Cell. 16:24-31.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 24-31
-
-
Pohl, J.1
Ring, A.2
Korkmaz, U.3
Ehehalt, R.4
Stremmel, W.5
-
105
-
-
41549146084
-
Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy
-
Kim, C.A., et al. 2008. Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy. J. Clin. Endocrinol. Metab. 93:1129-1134.
-
(2008)
J. Clin. Endocrinol. Metab
, vol.93
, pp. 1129-1134
-
-
Kim, C.A.1
-
106
-
-
0348038758
-
Hepatic uptake of chylomicron remnants in WHHL rabbits: A mechanism genetically distinct from the low density lipoprotein receptor
-
Kita, T., et al. 1982. Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. Proc. Natl. Acad. Sci. U. S. A. 79:3623-3627.
-
(1982)
Proc. Natl. Acad. Sci. U. S. A
, vol.79
, pp. 3623-3627
-
-
Kita, T.1
-
107
-
-
0025095799
-
Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects
-
Rubinsztein, D.C., et al. 1990. Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects. J. Clin. Invest. 86:1306-1312.
-
(1990)
J. Clin. Invest
, vol.86
, pp. 1306-1312
-
-
Rubinsztein, D.C.1
-
108
-
-
0029076825
-
Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor
-
Herz, J., et al. 1995. Initial hepatic removal of chylomicron remnants is unaffected but endocytosis is delayed in mice lacking the low density lipoprotein receptor. Proc. Natl. Acad. Sci. U. S. A. 92:4611-4615.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A
, vol.92
, pp. 4611-4615
-
-
Herz, J.1
-
109
-
-
0032004972
-
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants
-
Rohlmann, A., Gotthardt, M., Hammer, R.E., and Herz, J. 1998. Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants. J. Clin. Invest. 101:689-695.
-
(1998)
J. Clin. Invest
, vol.101
, pp. 689-695
-
-
Rohlmann, A.1
Gotthardt, M.2
Hammer, R.E.3
Herz, J.4
-
110
-
-
0025990629
-
Recognition of chylomicron remnants and beta-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver alpha 2-macroglobulin- recognition site
-
van Dijk, M.C.M., et al. 1991. Recognition of chylomicron remnants and beta-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver alpha 2-macroglobulin- recognition site. Biochem. J. 279:863-870.
-
(1991)
Biochem. J
, vol.279
, pp. 863-870
-
-
van Dijk, M.C.M.1
-
111
-
-
33846012847
-
Liver heparan sulfate proteoglycans mediate clearance of triglyceriderich lipoproteins independently of LDL receptor family members
-
MacArthur, J.M., et al. 2007. Liver heparan sulfate proteoglycans mediate clearance of triglyceriderich lipoproteins independently of LDL receptor family members. J. Clin. Invest. 117:153-164.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 153-164
-
-
MacArthur, J.M.1
-
112
-
-
33846024331
-
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia
-
Jones, C., et al. 2007. Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. J. Clin. Invest. 117:165-174.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 165-174
-
-
Jones, C.1
-
113
-
-
0033917880
-
Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice
-
Ebara, T., et al. 2000. Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice. J. Clin. Invest. 105:1807-1818.
-
(2000)
J. Clin. Invest
, vol.105
, pp. 1807-1818
-
-
Ebara, T.1
-
114
-
-
33749641662
-
Syndecan-1 mediates internalization of apoE-VLDL through a low density lipoprotein receptor-related protein (LRP)-independent, nonclathrin-mediated pathway
-
Wilsie, L.C., Gonzales, A.M., and Orlando, R.A. 2006. Syndecan-1 mediates internalization of apoE-VLDL through a low density lipoprotein receptor-related protein (LRP)-independent, nonclathrin-mediated pathway. Lipids Health Dis. 5:23.
-
(2006)
Lipids Health Dis
, vol.5
, pp. 23
-
-
Wilsie, L.C.1
Gonzales, A.M.2
Orlando, R.A.3
-
115
-
-
0034682850
-
Perlecan heparan sulfate proteoglycan: A novel receptor that mediates a distinct pathway for ligand catabolism
-
Fuki, I.V., Iozzo, R.V., and Williams, K.J. 2000. Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism. J. Biol. Chem. 275:25742-25750.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 25742-25750
-
-
Fuki, I.V.1
Iozzo, R.V.2
Williams, K.J.3
-
116
-
-
9644270384
-
The perlecan heparan sulfate proteoglycan mediates cellular uptake of HIV-1 Tat through a pathway responsible for biological activity
-
Argyris, E.G., et al. 2004. The perlecan heparan sulfate proteoglycan mediates cellular uptake of HIV-1 Tat through a pathway responsible for biological activity. Virology. 330:481-486.
-
(2004)
Virology
, vol.330
, pp. 481-486
-
-
Argyris, E.G.1
-
117
-
-
0345689423
-
Glypican-1 is a vehicle for polyamine uptake in mammalian cells: A pivital role for nitrosothiol-derived nitric oxide
-
Belting, M., et al. 2003. Glypican-1 is a vehicle for polyamine uptake in mammalian cells: a pivital role for nitrosothiol-derived nitric oxide. J. Biol. Chem. 278:47181-47189.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 47181-47189
-
-
Belting, M.1
-
118
-
-
0028948718
-
Heparan sulfate proteoglycan expression in normal human liver
-
Roskams, T., et al. 1995. Heparan sulfate proteoglycan expression in normal human liver. Hepatology. 21:950-958.
-
(1995)
Hepatology
, vol.21
, pp. 950-958
-
-
Roskams, T.1
-
119
-
-
0031830711
-
The short and long forms of type XVIII collagen show clear tissue specificities in their expression and location in basement membrane zones in humans
-
Saarela, J., Rehn, M., Oikarinen, A., Autio-Harmainen, H., and Pihlajaniemi, T. 1998. The short and long forms of type XVIII collagen show clear tissue specificities in their expression and location in basement membrane zones in humans. Am. J. Pathol. 153:611-626.
-
(1998)
Am. J. Pathol
, vol.153
, pp. 611-626
-
-
Saarela, J.1
Rehn, M.2
Oikarinen, A.3
Autio-Harmainen, H.4
Pihlajaniemi, T.5
-
120
-
-
31144473655
-
A focused microarray approach to functional glycomics: Transcriptional regulation of the glycome
-
Comelli, E.M., et al. 2006. A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology. 16:117-131.
-
(2006)
Glycobiology
, vol.16
, pp. 117-131
-
-
Comelli, E.M.1
-
121
-
-
0037380270
-
Chylomicron remnant metabolism studied with a new breath test in postmenopausal women with and without type 2 diabetes mellitus
-
Dane-Stewart, C.A., et al. 2003. Chylomicron remnant metabolism studied with a new breath test in postmenopausal women with and without type 2 diabetes mellitus. Clin. Endocrinol. (Oxf.) 58:415-420.
-
(2003)
Clin. Endocrinol. (Oxf.)
, vol.58
, pp. 415-420
-
-
Dane-Stewart, C.A.1
-
122
-
-
15944370936
-
Loss of heparan N-sulfotransferase in diabetic liver: Role of angiotensin II
-
Williams, K.J., et al. 2005. Loss of heparan N-sulfotransferase in diabetic liver: role of angiotensin II. Diabetes. 54:1116-1122.
-
(2005)
Diabetes
, vol.54
, pp. 1116-1122
-
-
Williams, K.J.1
-
123
-
-
0020660914
-
Reduced sulfation of liver heparan sulfate in experimentally diabetic rats
-
Kjellén, L., Bielefeld, D., and Hook, M. 1983. Reduced sulfation of liver heparan sulfate in experimentally diabetic rats. Diabetes. 32:337-342.
-
(1983)
Diabetes
, vol.32
, pp. 337-342
-
-
Kjellén, L.1
Bielefeld, D.2
Hook, M.3
-
124
-
-
0035462464
-
Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance
-
Olsson, U., et al. 2001. Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance. Diabetes. 50:2126-2132.
-
(2001)
Diabetes
, vol.50
, pp. 2126-2132
-
-
Olsson, U.1
-
125
-
-
1842527650
-
Glucose regulates the expression of the farnesoid X receptor in liver
-
Duran-Sandoval, D., et al. 2004. Glucose regulates the expression of the farnesoid X receptor in liver. Diabetes. 53:890-898.
-
(2004)
Diabetes
, vol.53
, pp. 890-898
-
-
Duran-Sandoval, D.1
-
126
-
-
0038482184
-
Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor
-
Anisfeld, A.M., et al. 2003. Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor. J. Biol. Chem. 278:20420-20428.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 20420-20428
-
-
Anisfeld, A.M.1
-
127
-
-
0036170674
-
Food restriction normalizes chylomicron remnant metabolism in murine models of obesity as assessed by a novel stable isotope breath test
-
Martins, I.J., Tran, J.M., and Redgrave, T.G. 2002. Food restriction normalizes chylomicron remnant metabolism in murine models of obesity as assessed by a novel stable isotope breath test. J. Nutr. 132:176-181.
-
(2002)
J. Nutr
, vol.132
, pp. 176-181
-
-
Martins, I.J.1
Tran, J.M.2
Redgrave, T.G.3
-
128
-
-
0035658035
-
Effects of short-term modest weight loss on fasting and post-prandial lipoprotein sub-fractions in type 2 diabetes mellitus patients
-
Ybarra, J., James, R.W., Makoundou, V., Bioletto, S., and Golay, A. 2001. Effects of short-term modest weight loss on fasting and post-prandial lipoprotein sub-fractions in type 2 diabetes mellitus patients. Diabetes Metab. 27:701-708.
-
(2001)
Diabetes Metab
, vol.27
, pp. 701-708
-
-
Ybarra, J.1
James, R.W.2
Makoundou, V.3
Bioletto, S.4
Golay, A.5
-
129
-
-
38049144162
-
Scavenger receptor BI facilitates the metabolism of very-low-density lipoproteins in vivo
-
Van Eck, M., et al. 2008. Scavenger receptor BI facilitates the metabolism of very-low-density lipoproteins in vivo. J. Lipid Res. 49:136-146.
-
(2008)
J. Lipid Res
, vol.49
, pp. 136-146
-
-
Van Eck, M.1
|