-
1
-
-
0030014002
-
T-cell-receptor affinity and thymocyte positive selection
-
Alam S.M., Travers P.J., Wung J.L., Nasholds W., Redpath S., Jameson S.C., and Gascoigne N.R. T-cell-receptor affinity and thymocyte positive selection. Nature 381 (1996) 616-620
-
(1996)
Nature
, vol.381
, pp. 616-620
-
-
Alam, S.M.1
Travers, P.J.2
Wung, J.L.3
Nasholds, W.4
Redpath, S.5
Jameson, S.C.6
Gascoigne, N.R.7
-
2
-
-
0842325739
-
PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells
-
Blank C., Brown I., Peterson A.C., Spiotto M., Iwai Y., Honjo T., and Gajewski T.F. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res. 64 (2004) 1140-1145
-
(2004)
Cancer Res.
, vol.64
, pp. 1140-1145
-
-
Blank, C.1
Brown, I.2
Peterson, A.C.3
Spiotto, M.4
Iwai, Y.5
Honjo, T.6
Gajewski, T.F.7
-
3
-
-
3042844293
-
Cancer immunotherapy: a treatment for the masses
-
Blattman J.N., and Greenberg P.D. Cancer immunotherapy: a treatment for the masses. Science 305 (2004) 200-205
-
(2004)
Science
, vol.305
, pp. 200-205
-
-
Blattman, J.N.1
Greenberg, P.D.2
-
4
-
-
0030994634
-
Yeast surface display for screening combinatorial polypeptide libraries
-
Boder E.T., and Wittrup K.D. Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotechnol. 15 (1997) 553-557
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 553-557
-
-
Boder, E.T.1
Wittrup, K.D.2
-
5
-
-
28344437532
-
Stable, soluble, high-affinity, engineered T cell receptors: novel antibody-like proteins for specific targeting of peptide antigens
-
Boulter J.M., and Jakobsen B.K. Stable, soluble, high-affinity, engineered T cell receptors: novel antibody-like proteins for specific targeting of peptide antigens. Clin. Exp. Immunol. 142 (2005) 454-460
-
(2005)
Clin. Exp. Immunol.
, vol.142
, pp. 454-460
-
-
Boulter, J.M.1
Jakobsen, B.K.2
-
6
-
-
17644395663
-
The T cell receptor: critical role of the membrane environment in receptor assembly and function
-
Call M.E., and Wucherpfennig K.W. The T cell receptor: critical role of the membrane environment in receptor assembly and function. Annu. Rev. Immunol. 23 (2005) 101-125
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 101-125
-
-
Call, M.E.1
Wucherpfennig, K.W.2
-
7
-
-
0015861774
-
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
-
Cheng Y., and Prusoff W.H. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 22 (1973) 3099-3108
-
(1973)
Biochem. Pharmacol.
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.1
Prusoff, W.H.2
-
8
-
-
0035852736
-
Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor
-
Cho B.K., Lian K.C., Lee P., Brunmark A., McKinley C., Chen J., Kranz D.M., and Eisen H.N. Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 1723-1727
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 1723-1727
-
-
Cho, B.K.1
Lian, K.C.2
Lee, P.3
Brunmark, A.4
McKinley, C.5
Chen, J.6
Kranz, D.M.7
Eisen, H.N.8
-
9
-
-
0034677055
-
Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
-
Daniels M.A., and Jameson S.C. Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers. J. Exp. Med. 191 (2000) 335-346
-
(2000)
J. Exp. Med.
, vol.191
, pp. 335-346
-
-
Daniels, M.A.1
Jameson, S.C.2
-
10
-
-
33845607123
-
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
-
Daniels M.A., Teixeiro E., Gill J., Hausmann B., Roubaty D., Holmberg K., Werlen G., Hollander G.A., Gascoigne N.R., and Palmer E. Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling. Nature 444 (2006) 724-729
-
(2006)
Nature
, vol.444
, pp. 724-729
-
-
Daniels, M.A.1
Teixeiro, E.2
Gill, J.3
Hausmann, B.4
Roubaty, D.5
Holmberg, K.6
Werlen, G.7
Hollander, G.A.8
Gascoigne, N.R.9
Palmer, E.10
-
11
-
-
17344362313
-
Ligand recognition by alpha beta T cell receptors
-
Davis M.M., Boniface J.J., Reich Z., Lyons D., Hampl J., Arden B., and Chien Y. Ligand recognition by alpha beta T cell receptors. Annu. Rev. Immunol. 16 (1998) 523-544
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 523-544
-
-
Davis, M.M.1
Boniface, J.J.2
Reich, Z.3
Lyons, D.4
Hampl, J.5
Arden, B.6
Chien, Y.7
-
12
-
-
0033679767
-
A functional hot spot for antigen recognition in a superagonist TCR/MHC complex
-
Degano M., Garcia K.C., Apostolopoulos V., Rudolph M.G., Teyton L., and Wilson I.A. A functional hot spot for antigen recognition in a superagonist TCR/MHC complex. Immunity 12 (2000) 251-261
-
(2000)
Immunity
, vol.12
, pp. 251-261
-
-
Degano, M.1
Garcia, K.C.2
Apostolopoulos, V.3
Rudolph, M.G.4
Teyton, L.5
Wilson, I.A.6
-
13
-
-
0141688283
-
Adoptive-cell-transfer therapy for the treatment of patients with cancer
-
Dudley M.E., and Rosenberg S.A. Adoptive-cell-transfer therapy for the treatment of patients with cancer. Nat. Rev., Cancer 3 (2003) 666-675
-
(2003)
Nat. Rev., Cancer
, vol.3
, pp. 666-675
-
-
Dudley, M.E.1
Rosenberg, S.A.2
-
14
-
-
33847322059
-
Redirecting T lymphocyte specificity by T cell receptor gene transfer-a new era for immunotherapy
-
Engels B., and Uckert W. Redirecting T lymphocyte specificity by T cell receptor gene transfer-a new era for immunotherapy. Mol. Aspects Med. 28 (2007) 115-142
-
(2007)
Mol. Aspects Med.
, vol.28
, pp. 115-142
-
-
Engels, B.1
Uckert, W.2
-
15
-
-
34648832245
-
Yeast surface display for protein engineering and characterization
-
Gai S.A., and Wittrup K.D. Yeast surface display for protein engineering and characterization. Curr. Opin. Struct. Biol. 17 (2007) 467-473
-
(2007)
Curr. Opin. Struct. Biol.
, vol.17
, pp. 467-473
-
-
Gai, S.A.1
Wittrup, K.D.2
-
16
-
-
33645071052
-
Central tolerance: good but imperfect
-
Gallegos A.M., and Bevan M.J. Central tolerance: good but imperfect. Immunol. Rev. 209 (2006) 290-296
-
(2006)
Immunol. Rev.
, vol.209
, pp. 290-296
-
-
Gallegos, A.M.1
Bevan, M.J.2
-
17
-
-
0031283279
-
Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization
-
Garcia K.C., Tallquist M.D., Pease L.R., Brunmark A., Scott C.A., Degano M., Stura E.A., Peterson P.A., Wilson I.A., and Teyton L. Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 13838-13843
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13838-13843
-
-
Garcia, K.C.1
Tallquist, M.D.2
Pease, L.R.3
Brunmark, A.4
Scott, C.A.5
Degano, M.6
Stura, E.A.7
Peterson, P.A.8
Wilson, I.A.9
Teyton, L.10
-
19
-
-
0028220953
-
Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping. Correlation with immune status
-
Gorski J., Yassai M., Zhu X., Kissela B., Kissella B., Keever C., and Flomenberg N. Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping. Correlation with immune status. J. Immunol. 152 (1994) 5109-5119
-
(1994)
J. Immunol.
, vol.152
, pp. 5109-5119
-
-
Gorski, J.1
Yassai, M.2
Zhu, X.3
Kissela, B.4
Kissella, B.5
Keever, C.6
Flomenberg, N.7
-
20
-
-
1542404892
-
Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction
-
Ho W.Y., Blattman J.N., Dossett M.L., Yee C., and Greenberg P.D. Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction. Cancer Cell 3 (2003) 431-437
-
(2003)
Cancer Cell
, vol.3
, pp. 431-437
-
-
Ho, W.Y.1
Blattman, J.N.2
Dossett, M.L.3
Yee, C.4
Greenberg, P.D.5
-
22
-
-
0037331525
-
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation
-
Holler P.D., and Kranz D.M. Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. Immunity 18 (2003) 255-264
-
(2003)
Immunity
, vol.18
, pp. 255-264
-
-
Holler, P.D.1
Kranz, D.M.2
-
23
-
-
0034624983
-
In vitro evolution of a T cell receptor with high affinity for peptide/MHC
-
Holler P.D., Holman P.O., Shusta E.V., O'Herrin S., Wittrup K.D., and Kranz D.M. In vitro evolution of a T cell receptor with high affinity for peptide/MHC. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 5387-5392
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5387-5392
-
-
Holler, P.D.1
Holman, P.O.2
Shusta, E.V.3
O'Herrin, S.4
Wittrup, K.D.5
Kranz, D.M.6
-
24
-
-
0035887216
-
CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation
-
Holler P.D., Lim A.R., Cho B.K., Rund L.A., and Kranz D.M. CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. J. Exp. Med. 194 (2001) 1043-1052
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1043-1052
-
-
Holler, P.D.1
Lim, A.R.2
Cho, B.K.3
Rund, L.A.4
Kranz, D.M.5
-
25
-
-
0037234768
-
TCRs with high affinity for foreign pMHC show self-reactivity
-
Holler P.D., Chlewicki L.K., and Kranz D.M. TCRs with high affinity for foreign pMHC show self-reactivity. Nat. Immunol. 4 (2003) 55-62
-
(2003)
Nat. Immunol.
, vol.4
, pp. 55-62
-
-
Holler, P.D.1
Chlewicki, L.K.2
Kranz, D.M.3
-
26
-
-
33748751008
-
Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld
-
Jones L.L., Brophy S.E., Bankovich A.J., Colf L.A., Hanick N.A., Garcia K.C., and Kranz D.M. Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld. J. Biol. Chem. 281 (2006) 25734-25744
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 25734-25744
-
-
Jones, L.L.1
Brophy, S.E.2
Bankovich, A.J.3
Colf, L.A.4
Hanick, N.A.5
Garcia, K.C.6
Kranz, D.M.7
-
27
-
-
55749090111
-
-
Jones, L.L., Colf, L.A., Stone, J.D.,Garcia, K.C., Kranz, D.M., in press. Distinct CDR3 conformations in T cell receptors determine the level of cross-reactivity for diverse antigens, but not the docking orientation. J. Immunol.
-
Jones, L.L., Colf, L.A., Stone, J.D.,Garcia, K.C., Kranz, D.M., in press. Distinct CDR3 conformations in T cell receptors determine the level of cross-reactivity for diverse antigens, but not the docking orientation. J. Immunol.
-
-
-
-
28
-
-
0023663430
-
T cell tolerance by clonal elimination in the thymus
-
Kappler J.W., Roehm N., and Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 49 (1987) 273-280
-
(1987)
Cell
, vol.49
, pp. 273-280
-
-
Kappler, J.W.1
Roehm, N.2
Marrack, P.3
-
29
-
-
0028986924
-
TCR alpha-CD3 delta epsilon association is the initial step in alpha beta dimer formation in murine T cells and is limiting in immature CD4+ CD8+ thymocytes
-
Kearse K.P., Roberts J.L., and Singer A. TCR alpha-CD3 delta epsilon association is the initial step in alpha beta dimer formation in murine T cells and is limiting in immature CD4+ CD8+ thymocytes. Immunity 2 (1995) 391-399
-
(1995)
Immunity
, vol.2
, pp. 391-399
-
-
Kearse, K.P.1
Roberts, J.L.2
Singer, A.3
-
30
-
-
0034687706
-
Changing T cell specificity by retroviral T cell receptor display
-
Kessels H.W., van Den Boom M.D., Spits H., Hooijberg E., and Schumacher T.N. Changing T cell specificity by retroviral T cell receptor display. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 14578-14583
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 14578-14583
-
-
Kessels, H.W.1
van Den Boom, M.D.2
Spits, H.3
Hooijberg, E.4
Schumacher, T.N.5
-
31
-
-
0033545862
-
Selection of functional T cell receptor mutants from a yeast surface-display library
-
Kieke M.C., Shusta E.V., Boder E.T., Teyton L., Wittrup K.D., and Kranz D.M. Selection of functional T cell receptor mutants from a yeast surface-display library. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 5651-5656
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 5651-5656
-
-
Kieke, M.C.1
Shusta, E.V.2
Boder, E.T.3
Teyton, L.4
Wittrup, K.D.5
Kranz, D.M.6
-
32
-
-
0021713437
-
Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes
-
Kranz D.M., Tonegawa S., and Eisen H.N. Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 81 (1984) 7922-7926
-
(1984)
Proc. Natl. Acad. Sci. U. S. A.
, vol.81
, pp. 7922-7926
-
-
Kranz, D.M.1
Tonegawa, S.2
Eisen, H.N.3
-
33
-
-
32244435875
-
Deconstructing the form and function of the TCR/CD3 complex
-
Kuhns M.S., Davis M.M., and Garcia K.C. Deconstructing the form and function of the TCR/CD3 complex. Immunity 24 (2006) 133-139
-
(2006)
Immunity
, vol.24
, pp. 133-139
-
-
Kuhns, M.S.1
Davis, M.M.2
Garcia, K.C.3
-
34
-
-
0024845198
-
Derivation of a T cell hybridoma variant deprived of functional T cell receptor alpha and beta chain transcripts reveals a nonfunctional alpha-mRNA of BW5147 origin
-
Letourneur F., and Malissen B. Derivation of a T cell hybridoma variant deprived of functional T cell receptor alpha and beta chain transcripts reveals a nonfunctional alpha-mRNA of BW5147 origin. Eur. J. Immunol. 19 (1989) 2269-2274
-
(1989)
Eur. J. Immunol.
, vol.19
, pp. 2269-2274
-
-
Letourneur, F.1
Malissen, B.2
-
35
-
-
21444445173
-
Directed evolution of human T-cell receptors with picomolar affinities by phage display
-
Li Y., Moysey R., Molloy P.E., Vuidepot A.L., Mahon T., Baston E., Dunn S., Liddy N., Jacob J., Jakobsen B.K., and Boulter J.M. Directed evolution of human T-cell receptors with picomolar affinities by phage display. Nat. Biotechnol. 23 (2005) 349-354
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 349-354
-
-
Li, Y.1
Moysey, R.2
Molloy, P.E.3
Vuidepot, A.L.4
Mahon, T.5
Baston, E.6
Dunn, S.7
Liddy, N.8
Jacob, J.9
Jakobsen, B.K.10
Boulter, J.M.11
-
36
-
-
34247098240
-
Evolution of an interloop disulfide bond in high-affinity antibody mimics based on fibronectin type III domain and selected by yeast surface display: molecular convergence with single-domain camelid and shark antibodies
-
Lipovsek D., Lippow S.M., Hackel B.J., Gregson M.W., Cheng P., Kapila A., and Wittrup K.D. Evolution of an interloop disulfide bond in high-affinity antibody mimics based on fibronectin type III domain and selected by yeast surface display: molecular convergence with single-domain camelid and shark antibodies. J. Mol. Biol. 368 (2007) 1024-1041
-
(2007)
J. Mol. Biol.
, vol.368
, pp. 1024-1041
-
-
Lipovsek, D.1
Lippow, S.M.2
Hackel, B.J.3
Gregson, M.W.4
Cheng, P.5
Kapila, A.6
Wittrup, K.D.7
-
37
-
-
0028589333
-
Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness
-
Matsui K., Boniface J.J., Steffner P., Reay P.A., and Davis M.M. Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 12862-12866
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 12862-12866
-
-
Matsui, K.1
Boniface, J.J.2
Steffner, P.3
Reay, P.A.4
Davis, M.M.5
-
39
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan R.A., Dudley M.E., Wunderlich J.R., Hughes M.S., Yang J.C., Sherry R.M., Royal R.E., Topalian S.L., Kammula U.S., Restifo N.P., Zheng Z., Nahvi A., de Vries C.R., Rogers-Freezer L.J., Mavroukakis S.A., and Rosenberg S.A. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314 (2006) 126-129
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
Royal, R.E.7
Topalian, S.L.8
Kammula, U.S.9
Restifo, N.P.10
Zheng, Z.11
Nahvi, A.12
de Vries, C.R.13
Rogers-Freezer, L.J.14
Mavroukakis, S.A.15
Rosenberg, S.A.16
-
40
-
-
34548592046
-
Display, engineering, and applications of antigen-specific T cell receptors
-
Richman S.A., and Kranz D.M. Display, engineering, and applications of antigen-specific T cell receptors. Biomol. Eng. 24 (2007) 361-373
-
(2007)
Biomol. Eng.
, vol.24
, pp. 361-373
-
-
Richman, S.A.1
Kranz, D.M.2
-
41
-
-
59249094502
-
-
Richman, S.A., Aggen, D.H., Dossett, M.L., Donermeyer, D.L., Allen, P.M., Greenberg, P.D., Kranz, D.M., 2008. Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain VαVβ fragments. Mol. Immunol. doi:10.1016/j.molimm.2008.09.021.
-
Richman, S.A., Aggen, D.H., Dossett, M.L., Donermeyer, D.L., Allen, P.M., Greenberg, P.D., Kranz, D.M., 2008. Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain VαVβ fragments. Mol. Immunol. doi:10.1016/j.molimm.2008.09.021.
-
-
-
-
42
-
-
44449128698
-
Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions
-
Robbins P.F., Li Y.F., El-Gamil M., Zhao Y., Wargo J.A., Zheng Z., Xu H., Morgan R.A., Feldman S.A., Johnson L.A., Bennett A.D., Dunn S.M., Mahon T.M., Jakobsen B.K., and Rosenberg S.A. Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions. J. Immunol. 180 (2008) 6116-6131
-
(2008)
J. Immunol.
, vol.180
, pp. 6116-6131
-
-
Robbins, P.F.1
Li, Y.F.2
El-Gamil, M.3
Zhao, Y.4
Wargo, J.A.5
Zheng, Z.6
Xu, H.7
Morgan, R.A.8
Feldman, S.A.9
Johnson, L.A.10
Bennett, A.D.11
Dunn, S.M.12
Mahon, T.M.13
Jakobsen, B.K.14
Rosenberg, S.A.15
-
43
-
-
41149097574
-
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
-
Rosenberg S.A., Restifo N.P., Yang J.C., Morgan R.A., and Dudley M.E. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat. Rev., Cancer 8 (2008) 299-308
-
(2008)
Nat. Rev., Cancer
, vol.8
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
Morgan, R.A.4
Dudley, M.E.5
-
44
-
-
33646181088
-
How TCRs bind MHCs, peptides, and coreceptors
-
Rudolph M.G., Stanfield R.L., and Wilson I.A. How TCRs bind MHCs, peptides, and coreceptors. Annu. Rev. Immunol. 24 (2006) 419-466
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 419-466
-
-
Rudolph, M.G.1
Stanfield, R.L.2
Wilson, I.A.3
-
45
-
-
0027172622
-
Retroviral vectors displaying functional antibody fragments
-
Russell S.J., Hawkins R.E., and Winter G. Retroviral vectors displaying functional antibody fragments. Nucleic Acids Res. 21 (1993) 1081-1085
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 1081-1085
-
-
Russell, S.J.1
Hawkins, R.E.2
Winter, G.3
-
46
-
-
0030219704
-
Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity
-
Schodin B.A., Tsomides T.J., and Kranz D.M. Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity. Immunity 5 (1996) 137-146
-
(1996)
Immunity
, vol.5
, pp. 137-146
-
-
Schodin, B.A.1
Tsomides, T.J.2
Kranz, D.M.3
-
47
-
-
0036635506
-
T-cell-receptor gene therapy
-
Schumacher T.N. T-cell-receptor gene therapy. Nat. Rev., Immunol. 2 (2002) 512-519
-
(2002)
Nat. Rev., Immunol.
, vol.2
, pp. 512-519
-
-
Schumacher, T.N.1
-
48
-
-
0033926329
-
Directed evolution of a stable scaffold for T-cell receptor engineering
-
Shusta E.V., Holler P.D., Kieke M.C., Kranz D.M., and Wittrup K.D. Directed evolution of a stable scaffold for T-cell receptor engineering. Nat. Biotechnol. 18 (2000) 754-759
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 754-759
-
-
Shusta, E.V.1
Holler, P.D.2
Kieke, M.C.3
Kranz, D.M.4
Wittrup, K.D.5
-
49
-
-
0036911269
-
Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells
-
Spiotto M.T., Yu P., Rowley D.A., Nishimura M.I., Meredith S.C., Gajewski T.F., Fu Y.X., and Schreiber H. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity 17 (2002) 737-747
-
(2002)
Immunity
, vol.17
, pp. 737-747
-
-
Spiotto, M.T.1
Yu, P.2
Rowley, D.A.3
Nishimura, M.I.4
Meredith, S.C.5
Gajewski, T.F.6
Fu, Y.X.7
Schreiber, H.8
-
50
-
-
0028410566
-
Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes
-
Sykulev Y., Brunmark A., Jackson M., Cohen R.J., Peterson P.A., and Eisen H.N. Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity 1 (1994) 15-22
-
(1994)
Immunity
, vol.1
, pp. 15-22
-
-
Sykulev, Y.1
Brunmark, A.2
Jackson, M.3
Cohen, R.J.4
Peterson, P.A.5
Eisen, H.N.6
-
51
-
-
46449122768
-
Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold
-
Tereshko V., Uysal S., Koide A., Margalef K., Koide S., and Kossiakoff A.A. Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold. Protein Sci. 17 (2008) 1175-1187
-
(2008)
Protein Sci.
, vol.17
, pp. 1175-1187
-
-
Tereshko, V.1
Uysal, S.2
Koide, A.3
Margalef, K.4
Koide, S.5
Kossiakoff, A.A.6
-
52
-
-
45849084617
-
Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors
-
Thomas D.L., Kranz D.M., and Roy E.J. Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors. Cancer Immunol. Immunother. 57 (2008) 1323-1333
-
(2008)
Cancer Immunol. Immunother.
, vol.57
, pp. 1323-1333
-
-
Thomas, D.L.1
Kranz, D.M.2
Roy, E.J.3
-
53
-
-
0029902364
-
Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone
-
Udaka K., Wiesmuller K.H., Kienle S., Jung G., and Walden P. Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone. J Immunol 157 (1996) 670-678
-
(1996)
J Immunol
, vol.157
, pp. 670-678
-
-
Udaka, K.1
Wiesmuller, K.H.2
Kienle, S.3
Jung, G.4
Walden, P.5
-
54
-
-
26644448210
-
Selection of functional human antibodies from retroviral display libraries
-
Urban J.H., Schneider R.M., Compte M., Finger C., Cichutek K., Alvarez-Vallina L., and Buchholz C.J. Selection of functional human antibodies from retroviral display libraries. Nucleic Acids Res. 33 (2005) e35
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Urban, J.H.1
Schneider, R.M.2
Compte, M.3
Finger, C.4
Cichutek, K.5
Alvarez-Vallina, L.6
Buchholz, C.J.7
-
55
-
-
0042971650
-
Molecular interactions mediating T cell antigen recognition
-
van der Merwe P.A., and Davis S.J. Molecular interactions mediating T cell antigen recognition. Annu. Rev. Immunol. 21 (2003) 659-684
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 659-684
-
-
van der Merwe, P.A.1
Davis, S.J.2
-
56
-
-
30044449525
-
Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function
-
Weber K.S., Donermeyer D.L., Allen P.M., and Kranz D.M. Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 19033-19038
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 19033-19038
-
-
Weber, K.S.1
Donermeyer, D.L.2
Allen, P.M.3
Kranz, D.M.4
-
57
-
-
0026544338
-
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules
-
Wegener A.M., Letourneur F., Hoeveler A., Brocker T., Luton F., and Malissen B. The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell 68 (1992) 83-95
-
(1992)
Cell
, vol.68
, pp. 83-95
-
-
Wegener, A.M.1
Letourneur, F.2
Hoeveler, A.3
Brocker, T.4
Luton, F.5
Malissen, B.6
-
58
-
-
33846429184
-
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells
-
Zhang B., Bowerman N.A., Salama J.K., Schmidt H., Spiotto M.T., Schietinger A., Yu P., Fu Y.X., Weichselbaum R.R., Rowley D.A., Kranz D.M., and Schreiber H. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. J. Exp. Med. 204 (2007) 49-55
-
(2007)
J. Exp. Med.
, vol.204
, pp. 49-55
-
-
Zhang, B.1
Bowerman, N.A.2
Salama, J.K.3
Schmidt, H.4
Spiotto, M.T.5
Schietinger, A.6
Yu, P.7
Fu, Y.X.8
Weichselbaum, R.R.9
Rowley, D.A.10
Kranz, D.M.11
Schreiber, H.12
-
59
-
-
41849103115
-
IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers
-
Zhang B., Karrison T., Rowley D.A., and Schreiber H. IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers. J. Clin. Invest. 118 (2008) 1398-1404
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1398-1404
-
-
Zhang, B.1
Karrison, T.2
Rowley, D.A.3
Schreiber, H.4
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