메뉴 건너뛰기




Volumn 118, Issue 4, 2008, Pages 1398-1404

IFN-γ- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; PERFORIN; TUMOR NECROSIS FACTOR;

EID: 41849103115     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI33522     Document Type: Article
Times cited : (131)

References (63)
  • 1
    • 0024383883 scopus 로고
    • Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells
    • Ward, P.L., Koeppen, H., Hurteau, T., and Schreiber, H. 1989. Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells. J. Exp. Med. 170:217-232.
    • (1989) J. Exp. Med , vol.170 , pp. 217-232
    • Ward, P.L.1    Koeppen, H.2    Hurteau, T.3    Schreiber, H.4
  • 2
    • 0029924107 scopus 로고    scopus 로고
    • Human tumor antigens recognized by T lymphocytes
    • Boon, T., and van der Bruggen, P. 1996. Human tumor antigens recognized by T lymphocytes. J. Exp. Med. 183:725-729.
    • (1996) J. Exp. Med , vol.183 , pp. 725-729
    • Boon, T.1    van der Bruggen, P.2
  • 3
    • 0019977370 scopus 로고
    • Immunoselection of tumor cell variants by mice suppressed with ultraviolet radiation
    • Urban, J.L., Holland, J.M., Kripke, M.L., and Schreiber, H. 1982. Immunoselection of tumor cell variants by mice suppressed with ultraviolet radiation. J. Exp. Med. 156:1025-1041.
    • (1982) J. Exp. Med , vol.156 , pp. 1025-1041
    • Urban, J.L.1    Holland, J.M.2    Kripke, M.L.3    Schreiber, H.4
  • 4
    • 0020546609 scopus 로고
    • Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression
    • Uyttenhove, C., Maryanski, J., and Boon, T. 1983. Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression. J. Exp. Med. 157:1040-1052.
    • (1983) J. Exp. Med , vol.157 , pp. 1040-1052
    • Uyttenhove, C.1    Maryanski, J.2    Boon, T.3
  • 5
    • 0025288256 scopus 로고
    • Mechanisms of neutrophil-mediated killing of endothelial cells
    • Ward, P.A., and Varani, J. 1990. Mechanisms of neutrophil-mediated killing of endothelial cells. J. Leukoc. Biol. 48:97-102.
    • (1990) J. Leukoc. Biol , vol.48 , pp. 97-102
    • Ward, P.A.1    Varani, J.2
  • 6
    • 0037058993 scopus 로고    scopus 로고
    • Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
    • Yee, C., et al. 2002. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells. Proc. Natl. Acad. Sci. U. S. A. 99:16168-16173.
    • (2002) Proc. Natl. Acad. Sci. U. S. A , vol.99 , pp. 16168-16173
    • Yee, C.1
  • 7
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
    • Marincola, F.M., Jaffee, E.M., Hicklin, D.J., and Ferrone, S. 2000. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv. Immunol. 74:181-273.
    • (2000) Adv. Immunol , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 8
    • 2342485077 scopus 로고    scopus 로고
    • Bystander elimination of antigen loss variants in established tumors
    • Spiotto, M.T., Rowley, D.A., and Schreiber, H. 2004. Bystander elimination of antigen loss variants in established tumors. Nat. Med. 10:294-298.
    • (2004) Nat. Med , vol.10 , pp. 294-298
    • Spiotto, M.T.1    Rowley, D.A.2    Schreiber, H.3
  • 9
    • 85047690959 scopus 로고    scopus 로고
    • Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes
    • Bai, X.F., Liu, J., Li, O., Zheng, P., and Liu, Y. 2003. Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes. J. Clin. Invest. 111:1487-1496.
    • (2003) J. Clin. Invest , vol.111 , pp. 1487-1496
    • Bai, X.F.1    Liu, J.2    Li, O.3    Zheng, P.4    Liu, Y.5
  • 10
    • 33748051700 scopus 로고    scopus 로고
    • Different lineages of P1A-expressing cancer cells use divergent modes of immune evasion for T-cell adoptive therapy
    • Bai, X.F., et al. 2006. Different lineages of P1A-expressing cancer cells use divergent modes of immune evasion for T-cell adoptive therapy. Cancer Res. 66:8241-8249.
    • (2006) Cancer Res , vol.66 , pp. 8241-8249
    • Bai, X.F.1
  • 11
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell, P.C. 1976. The clonal evolution of tumor cell populations. Science. 194:23-28.
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 12
    • 0026547421 scopus 로고
    • Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells
    • Singh, S., Ross, S.R., Acena, M., Rowley, D.A., and Schreiber, H. 1992. Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells. J. Exp. Med. 175:139-146.
    • (1992) J. Exp. Med , vol.175 , pp. 139-146
    • Singh, S.1    Ross, S.R.2    Acena, M.3    Rowley, D.A.4    Schreiber, H.5
  • 13
    • 0033514923 scopus 로고    scopus 로고
    • Immune surveillance against a solid tumor fails because of immunological ignorance
    • Ochsenbein, A.F., et al. 1999. Immune surveillance against a solid tumor fails because of immunological ignorance. Proc. Natl. Acad. Sci. U. S. A. 96:2233-2238.
    • (1999) Proc. Natl. Acad. Sci. U. S. A , vol.96 , pp. 2233-2238
    • Ochsenbein, A.F.1
  • 14
    • 0035963379 scopus 로고    scopus 로고
    • Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction
    • Ochsenbein, A.F., et al. 2001. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature. 411:1058-1064.
    • (2001) Nature , vol.411 , pp. 1058-1064
    • Ochsenbein, A.F.1
  • 15
    • 0035153878 scopus 로고    scopus 로고
    • Presence of genetic alterations in microdissected stroma of human colon and breast cancers
    • Wernert, N., Locherbach, C., Wellmann, A., Behrens, P., and Hugel, A. 2001. Presence of genetic alterations in microdissected stroma of human colon and breast cancers. Anticancer Res. 21:2259-2264.
    • (2001) Anticancer Res , vol.21 , pp. 2259-2264
    • Wernert, N.1    Locherbach, C.2    Wellmann, A.3    Behrens, P.4    Hugel, A.5
  • 16
    • 0043236148 scopus 로고    scopus 로고
    • Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma
    • Matsumoto, N., Yoshida, T., Yamashita, K., Numata, Y., and Okayasu, I. 2003. Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma. Br. J. Cancer. 89:707-712.
    • (2003) Br. J. Cancer , vol.89 , pp. 707-712
    • Matsumoto, N.1    Yoshida, T.2    Yamashita, K.3    Numata, Y.4    Okayasu, I.5
  • 17
    • 23044499067 scopus 로고    scopus 로고
    • Distinct epigenetic changes in the stromal cells of breast cancers
    • Hu, M., et al. 2005. Distinct epigenetic changes in the stromal cells of breast cancers. Nat. Genet. 37:899-905.
    • (2005) Nat. Genet , vol.37 , pp. 899-905
    • Hu, M.1
  • 18
    • 34248564820 scopus 로고    scopus 로고
    • Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma
    • Fukino, K., Shen, L., Patocs, A., Mutter, G.L., and Eng, C. 2007. Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma. JAMA. 297:2103-2111.
    • (2007) JAMA , vol.297 , pp. 2103-2111
    • Fukino, K.1    Shen, L.2    Patocs, A.3    Mutter, G.L.4    Eng, C.5
  • 19
    • 33646249638 scopus 로고    scopus 로고
    • Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas
    • Ishiguro, K., Yoshida, T., Yagishita, H., Numata, Y., and Okayasu, T. 2006. Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas. Gut. 55:695-702.
    • (2006) Gut , vol.55 , pp. 695-702
    • Ishiguro, K.1    Yoshida, T.2    Yagishita, H.3    Numata, Y.4    Okayasu, T.5
  • 20
    • 2442621619 scopus 로고    scopus 로고
    • Case history: Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara, N., Hillan, K.J., Gerber, H.P., and Novotny, W. 2004. Case history: Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat. Rev. Drug Discov. 3:391-400.
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.P.3    Novotny, W.4
  • 21
    • 0037143764 scopus 로고    scopus 로고
    • VEGF-Trap: A VEGF blocker with potent antitumor effects
    • Holash, J., et al. 2002. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc. Natl. Acad. Sci. U. S. A. 99:11393-11398.
    • (2002) Proc. Natl. Acad. Sci. U. S. A , vol.99 , pp. 11393-11398
    • Holash, J.1
  • 22
    • 0043245914 scopus 로고    scopus 로고
    • Synergy between tumor immunotherapy and antiangiogenic therapy
    • Nair, S., et al. 2003. Synergy between tumor immunotherapy and antiangiogenic therapy. Blood. 102:964-971.
    • (2003) Blood , vol.102 , pp. 964-971
    • Nair, S.1
  • 23
    • 0037189380 scopus 로고    scopus 로고
    • Tumor regression by targeted gene delivery to the neovasculature
    • Hood, J.D., et al. 2002. Tumor regression by targeted gene delivery to the neovasculature. Science. 296:2404-2407.
    • (2002) Science , vol.296 , pp. 2404-2407
    • Hood, J.D.1
  • 24
    • 33749005405 scopus 로고    scopus 로고
    • Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors
    • Shaked, Y., et al. 2006. Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science. 313:1785-1787.
    • (2006) Science , vol.313 , pp. 1785-1787
    • Shaked, Y.1
  • 25
    • 0036913333 scopus 로고    scopus 로고
    • A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth
    • Niethammer, A.G., et al. 2002. A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth. Nat. Med. 8:1369-1375.
    • (2002) Nat. Med , vol.8 , pp. 1369-1375
    • Niethammer, A.G.1
  • 26
    • 28244447726 scopus 로고    scopus 로고
    • Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts
    • Lee, J., Fassnacht, M., Nair, S., Boczkowski, D., and Gilboa, E. 2005. Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts. Cancer Res. 65:11156-11163.
    • (2005) Cancer Res , vol.65 , pp. 11156-11163
    • Lee, J.1    Fassnacht, M.2    Nair, S.3    Boczkowski, D.4    Gilboa, E.5
  • 27
    • 23044481201 scopus 로고    scopus 로고
    • Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: Implication for cancer immunotherapy
    • Fassnacht, M., et al. 2005. Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy. Clin. Cancer Res. 11:5566-5571.
    • (2005) Clin. Cancer Res , vol.11 , pp. 5566-5571
    • Fassnacht, M.1
  • 28
    • 33746548452 scopus 로고    scopus 로고
    • Predicting benefit from anti-angiogenic agents in malignancy
    • Jubb, A.M., Oates, A.J., Holden, S., and Koeppen, H. 2006. Predicting benefit from anti-angiogenic agents in malignancy. Nat. Rev. Cancer. 6:626-635.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 626-635
    • Jubb, A.M.1    Oates, A.J.2    Holden, S.3    Koeppen, H.4
  • 29
    • 0037076297 scopus 로고    scopus 로고
    • Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors
    • Niederman, T.M., et al. 2002. Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors. Proc. Natl. Acad. Sci. U. S. A. 99:7009-7014.
    • (2002) Proc. Natl. Acad. Sci. U. S. A , vol.99 , pp. 7009-7014
    • Niederman, T.M.1
  • 30
    • 0028110345 scopus 로고
    • Immune function in mice lacking the perforin gene
    • Walsh, C.M., et al. 1994. Immune function in mice lacking the perforin gene. Proc. Natl. Acad. Sci. U. S. A. 91:10854-10858.
    • (1994) Proc. Natl. Acad. Sci. U. S. A , vol.91 , pp. 10854-10858
    • Walsh, C.M.1
  • 31
    • 18744399115 scopus 로고    scopus 로고
    • Neoplasia
    • 7th edition. V. Kumar, A. Abbas, and N. Fausto, editors. W.B. Saunders/Elsevier. Philadelphia, Pennsylvania, USA
    • Kumar, V., Fausto, N., and Abbas, A. 2004. Neoplasia. In Robbins and Cotran pathologic basis of disease. 7th edition. V. Kumar, A. Abbas, and N. Fausto, editors. W.B. Saunders/Elsevier. Philadelphia, Pennsylvania, USA. 269-342.
    • (2004) Robbins and Cotran pathologic basis of disease , pp. 269-342
    • Kumar, V.1    Fausto, N.2    Abbas, A.3
  • 32
    • 33744534978 scopus 로고    scopus 로고
    • Cancer immunotherapy and preclinical studies: Why we are not wasting our time with animal experiments
    • Schreiber, K., Rowley, D.A., Riethmuller, G., and Schreiber, H. 2006. Cancer immunotherapy and preclinical studies: why we are not wasting our time with animal experiments. Hematol. Oncol. Clin. North Am. 20:567-584.
    • (2006) Hematol. Oncol. Clin. North Am , vol.20 , pp. 567-584
    • Schreiber, K.1    Rowley, D.A.2    Riethmuller, G.3    Schreiber, H.4
  • 33
    • 0022592335 scopus 로고
    • Laboratory models: Some historical perspective
    • Skipper, H.E. 1986. Laboratory models: some historical perspective. Cancer Treat. Rep. 70:3-7.
    • (1986) Cancer Treat. Rep , vol.70 , pp. 3-7
    • Skipper, H.E.1
  • 34
    • 0003804879 scopus 로고
    • John Wiley. New York, New York, USA. 55 pp
    • Lewin, B. 1987. Genes III. John Wiley. New York, New York, USA. 55 pp.
    • (1987) Genes III
    • Lewin, B.1
  • 35
    • 0015388148 scopus 로고
    • Specificity of homograft rejection in vivo, assessed by inoculation of artificially mixed compatible and imcompatible tumor cells
    • Klein, E., and Klein, G. 1972. Specificity of homograft rejection in vivo, assessed by inoculation of artificially mixed compatible and imcompatible tumor cells. Cell Immunol. 5:201-208.
    • (1972) Cell Immunol , vol.5 , pp. 201-208
    • Klein, E.1    Klein, G.2
  • 36
    • 0015845909 scopus 로고
    • Tumor immunity in vivo: Evidence that immune destruction of tumor leaves "bystander" cells intact
    • Weissman, I.L. 1973. Tumor immunity in vivo: evidence that immune destruction of tumor leaves "bystander" cells intact. J. Natl. Cancer Inst. 51:443-448.
    • (1973) J. Natl. Cancer Inst , vol.51 , pp. 443-448
    • Weissman, I.L.1
  • 37
    • 0015593296 scopus 로고
    • Destruction of tumor as an "innocent bystander" in an immune response specifically directed against nontumor antigens
    • Prehn, R.T. 1973. Destruction of tumor as an "innocent bystander" in an immune response specifically directed against nontumor antigens. Isr. J. Med. Sci. 9:375-379.
    • (1973) Isr. J. Med. Sci , vol.9 , pp. 375-379
    • Prehn, R.T.1
  • 38
    • 0036911269 scopus 로고    scopus 로고
    • Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells
    • Spiotto, M.T., et al. 2002. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 17:737-747.
    • (2002) Immunity , vol.17 , pp. 737-747
    • Spiotto, M.T.1
  • 39
    • 33846429184 scopus 로고    scopus 로고
    • Induced sensitization of tumor stroma leads to eradication of established cancer by T cells
    • Zhang, B., et al. 2007. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. J. Exp. Med. 204:49-55.
    • (2007) J. Exp. Med , vol.204 , pp. 49-55
    • Zhang, B.1
  • 40
    • 0023092146 scopus 로고
    • Inhibition of tumor-induced migration of bovine capillary endothelial cells by mouse and rabbit tumor necrosis factor
    • Mano-Hirano, Y., et al. 1987. Inhibition of tumor-induced migration of bovine capillary endothelial cells by mouse and rabbit tumor necrosis factor. J. Natl. Cancer Inst. 78:115-120.
    • (1987) J. Natl. Cancer Inst , vol.78 , pp. 115-120
    • Mano-Hirano, Y.1
  • 41
    • 0022578656 scopus 로고
    • Actions of tumor necrosis factor on cultured vascular endothelial cells: Morphologic modulation, growth inhibition, and cytotoxicity
    • Sato, N., et al. 1986. Actions of tumor necrosis factor on cultured vascular endothelial cells: morphologic modulation, growth inhibition, and cytotoxicity. J. Natl. Cancer Inst. 76:1113-1121.
    • (1986) J. Natl. Cancer Inst , vol.76 , pp. 1113-1121
    • Sato, N.1
  • 42
    • 0023118633 scopus 로고
    • Inhibition of endothelial cell proliferation by gamma-interferon
    • Friesel, R., Komoriya, A., and Maciag, T. 1987. Inhibition of endothelial cell proliferation by gamma-interferon. J. Cell Biol. 104:689-696.
    • (1987) J. Cell Biol , vol.104 , pp. 689-696
    • Friesel, R.1    Komoriya, A.2    Maciag, T.3
  • 43
    • 0025037064 scopus 로고
    • IFN-gamma enhances endothelial activation induced by tumor necrosis factor but not IL-1
    • Doukas, J., and Pober, J.S. 1990. IFN-gamma enhances endothelial activation induced by tumor necrosis factor but not IL-1. J. Immunol. 145:1727-1733.
    • (1990) J. Immunol , vol.145 , pp. 1727-1733
    • Doukas, J.1    Pober, J.S.2
  • 44
    • 0040887215 scopus 로고    scopus 로고
    • Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma
    • Ruegg, C., et al. 1998. Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma. Nat. Med. 4:408-414.
    • (1998) Nat. Med , vol.4 , pp. 408-414
    • Ruegg, C.1
  • 45
    • 0020502358 scopus 로고
    • Identification of interferon-g as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity
    • Nathan, C., Murray, W., Wiebe, M.E., and Rubin, B.Y. 1983. Identification of interferon-g as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J. Exp. Med. 158:670-681.
    • (1983) J. Exp. Med , vol.158 , pp. 670-681
    • Nathan, C.1    Murray, W.2    Wiebe, M.E.3    Rubin, B.Y.4
  • 46
    • 0018949599 scopus 로고
    • Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)
    • Mannel, D.N., Moore, R.N., and Mergenhagen, S.E. 1980. Macrophages as a source of tumoricidal activity (tumor-necrotizing factor). Infect. Immun. 30:523-530.
    • (1980) Infect. Immun , vol.30 , pp. 523-530
    • Mannel, D.N.1    Moore, R.N.2    Mergenhagen, S.E.3
  • 49
    • 0037442129 scopus 로고    scopus 로고
    • TNF plays an essential role in tumor regression after adoptive transfer of perforin/IFN-gamma double knockout effector T cells
    • Poehlein, C.H., et al. 2003. TNF plays an essential role in tumor regression after adoptive transfer of perforin/IFN-gamma double knockout effector T cells. J. Immunol. 170:2004-2013.
    • (2003) J. Immunol , vol.170 , pp. 2004-2013
    • Poehlein, C.H.1
  • 50
    • 0030046658 scopus 로고    scopus 로고
    • Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection
    • Walsh, C.M., et al. 1996. Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection. J. Immunol. 156:1436-1441.
    • (1996) J. Immunol , vol.156 , pp. 1436-1441
    • Walsh, C.M.1
  • 51
    • 0042173089 scopus 로고    scopus 로고
    • A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8+ T cells
    • Qin, Z., Schwartzkopff, J., et al. 2003. A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8+ T cells. Cancer Res. 63:4095-4100.
    • (2003) Cancer Res , vol.63 , pp. 4095-4100
    • Qin, Z.1    Schwartzkopff, J.2
  • 52
    • 0343183120 scopus 로고    scopus 로고
    • Crucial role of TNF-alpha in CD8 T cell-mediated elimination of 3LL-A9 Lewis lung carcinoma cells in vivo
    • Prevost-Blondel, A., Roth, E., Rosenthal, F.M., and Pircher, H. 2000. Crucial role of TNF-alpha in CD8 T cell-mediated elimination of 3LL-A9 Lewis lung carcinoma cells in vivo. J. Immunol. 164:3645-3651.
    • (2000) J. Immunol , vol.164 , pp. 3645-3651
    • Prevost-Blondel, A.1    Roth, E.2    Rosenthal, F.M.3    Pircher, H.4
  • 53
    • 0034672005 scopus 로고    scopus 로고
    • T cell-mediated tumor rejection displays diverse dependence upon perforin and IFN-gamma mechanisms that cannot be predicted from in vitro T cell characteristics
    • Peng, L., et al. 2000. T cell-mediated tumor rejection displays diverse dependence upon perforin and IFN-gamma mechanisms that cannot be predicted from in vitro T cell characteristics. J. Immunol. 165:7116-7124.
    • (2000) J. Immunol , vol.165 , pp. 7116-7124
    • Peng, L.1
  • 54
    • 0032853311 scopus 로고    scopus 로고
    • Tumor regression after adoptive transfer of effector T cells is independent of perforin or Fas ligand (APO-1L/CD95L)
    • Winter, H., Hu, H.M., Urba, W.J., and Fox, B.A. 1999. Tumor regression after adoptive transfer of effector T cells is independent of perforin or Fas ligand (APO-1L/CD95L). J. Immunol. 163:4462-4472.
    • (1999) J. Immunol , vol.163 , pp. 4462-4472
    • Winter, H.1    Hu, H.M.2    Urba, W.J.3    Fox, B.A.4
  • 55
    • 3242771187 scopus 로고    scopus 로고
    • The rate of the CD8-dependent initial reduction in tumor volume is not limited by contact-dependent perforin, Fas ligand, or TNF-mediated cytolysis
    • Hollenbaugh, J.A., Reome, J., Dobrzanski, M., and Dutton, R.W. 2004. The rate of the CD8-dependent initial reduction in tumor volume is not limited by contact-dependent perforin, Fas ligand, or TNF-mediated cytolysis. J. Immunol. 173:1738-1743.
    • (2004) J. Immunol , vol.173 , pp. 1738-1743
    • Hollenbaugh, J.A.1    Reome, J.2    Dobrzanski, M.3    Dutton, R.W.4
  • 56
    • 0037406702 scopus 로고    scopus 로고
    • Cutting edge: CD8+ effector T cells reject tumors by direct antigen recognition but indirect action on host cells
    • Schuler, T., and Blankenstein, T. 2003. Cutting edge: CD8+ effector T cells reject tumors by direct antigen recognition but indirect action on host cells. J. Immunol. 170:4427-4431.
    • (2003) J. Immunol , vol.170 , pp. 4427-4431
    • Schuler, T.1    Blankenstein, T.2
  • 57
    • 0035182194 scopus 로고    scopus 로고
    • Immunopotentiating role of IFN-gamma in early and late stages of type 1 CD8 effector cell-mediated tumor rejection
    • Dobrzanski, M.J., Reome, J.B., and Dutton, R.W. 2001. Immunopotentiating role of IFN-gamma in early and late stages of type 1 CD8 effector cell-mediated tumor rejection. Clin. Immunol. 98:70-84.
    • (2001) Clin. Immunol , vol.98 , pp. 70-84
    • Dobrzanski, M.J.1    Reome, J.B.2    Dutton, R.W.3
  • 58
    • 0010733302 scopus 로고
    • Purification, characterization, and antitumor activity of nonrecombinant mouse tumor necrosis factor
    • Haranaka, K., et al. 1986. Purification, characterization, and antitumor activity of nonrecombinant mouse tumor necrosis factor. Proc. Natl. Acad. Sci. U. S. A. 83:3949-3953.
    • (1986) Proc. Natl. Acad. Sci. U. S. A , vol.83 , pp. 3949-3953
    • Haranaka, K.1
  • 59
    • 0033847207 scopus 로고    scopus 로고
    • Tumor necrosis factor induces tumor necrosis via tumor necrosis factor receptor type 1-expressing endothelial cells of the tumor vasculature
    • Stoelcker, B., et al. 2000. Tumor necrosis factor induces tumor necrosis via tumor necrosis factor receptor type 1-expressing endothelial cells of the tumor vasculature. Am. J. Pathol. 156:1171-1176.
    • (2000) Am. J. Pathol , vol.156 , pp. 1171-1176
    • Stoelcker, B.1
  • 60
    • 0023940875 scopus 로고
    • The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity
    • Havell, E.A., Fiers, W., and North, R.J. 1988. The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity. J. Exp. Med. 167:1067-1085.
    • (1988) J. Exp. Med , vol.167 , pp. 1067-1085
    • Havell, E.A.1    Fiers, W.2    North, R.J.3
  • 61
    • 0029642299 scopus 로고
    • Anti-tumor activity of tumor necrosis factor in combination with interferon-gamma is not affected by prior tolerization
    • Takahashi, N., Fiers, W., and Brouckaert, P. 1995. Anti-tumor activity of tumor necrosis factor in combination with interferon-gamma is not affected by prior tolerization. Int. J. Cancer. 63:846-854.
    • (1995) Int. J. Cancer , vol.63 , pp. 846-854
    • Takahashi, N.1    Fiers, W.2    Brouckaert, P.3
  • 62
    • 23044450840 scopus 로고    scopus 로고
    • Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells
    • Spiotto, M.T., and Schreiber, H. 2005. Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells. Cancer Immun. 5:8.
    • (2005) Cancer Immun , vol.5 , pp. 8
    • Spiotto, M.T.1    Schreiber, H.2
  • 63
    • 0032534058 scopus 로고    scopus 로고
    • Differentiation of naive CTL to effector and memory CTL: Correlation of effector function with phenotype and cell division
    • Oehen, S., and Brduscha-Riem, K. 1998. Differentiation of naive CTL to effector and memory CTL: correlation of effector function with phenotype and cell division. J. Immunol. 161:5338-5346.
    • (1998) J. Immunol , vol.161 , pp. 5338-5346
    • Oehen, S.1    Brduscha-Riem, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.